# GO NS enrichment name ratio_in_study ratio_in_pop p_uncorrected depth study_count p_fdr_bh study_items GO:0042221 BP e response to chemical 61/100 2603/19669 6.299054825176819e-29 2 61 6.673342149708525e-25 60, 196, 335, 348, 351, 383, 581, 847, 1244, 1440, 1571, 1719, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2947, 3146, 3162, 3309, 3440, 3479, 3553, 3569, 3627, 3654, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5166, 5243, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6649, 6652, 6696, 7422, 9370, 9474, 9971, 10096, 11035, 50507, 83667 GO:1901700 BP e response to oxygen-containing compound 47/100 1320/19669 8.672309486300877e-29 3 47 6.673342149708525e-25 60, 196, 348, 351, 383, 847, 1244, 1440, 1571, 1719, 2081, 2180, 2876, 2934, 3146, 3162, 3309, 3479, 3553, 3569, 3627, 3654, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 9370, 9971, 11035, 50507, 83667 GO:0009605 BP e response to external stimulus 51/100 1750/19669 1.684179150327425e-27 2 51 8.63983904117969e-24 213, 335, 348, 351, 383, 581, 847, 1244, 1401, 1440, 1571, 2023, 2180, 2243, 2876, 2934, 3075, 3146, 3162, 3309, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4217, 4524, 4780, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5836, 6347, 6622, 6652, 6696, 9370, 9474, 9971, 10383, 11035, 81631, 83667, 136319 GO:0006950 BP e response to stress 62/100 3071/19669 6.619336710055175e-26 2 62 2.4478634024368573e-22 213, 335, 348, 351, 383, 581, 821, 847, 1244, 1401, 1571, 1719, 2081, 2243, 2876, 2934, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6649, 6652, 6696, 7422, 7450, 9131, 9370, 9474, 9971, 10383, 11035, 23476, 50507, 81631, 83667, 729230 GO:0050896 BP e response to stimulus 78/100 5397/19669 7.952772587514154e-26 1 78 2.4478634024368573e-22 60, 183, 196, 213, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1401, 1440, 1571, 1719, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2947, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5166, 5243, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 7422, 7450, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 50507, 81631, 83667, 136319, 729230 GO:0010941 BP e regulation of cell death 47/100 1584/19669 2.479309596296656e-25 4 47 6.359429114500924e-22 183, 213, 348, 350, 383, 581, 847, 1440, 2023, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 9474, 9971, 11035, 50507 GO:0043067 BP e regulation of programmed cell death 45/100 1451/19669 6.753208969737121e-25 5 45 1.4847412292036326e-21 183, 213, 348, 350, 383, 581, 847, 2023, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 9474, 9971, 11035, 50507 GO:0010033 BP e response to organic substance 52/100 2097/19669 8.292957337194103e-25 3 52 1.5953576677427157e-21 60, 196, 335, 351, 383, 581, 847, 1244, 1440, 1571, 1719, 2081, 2180, 2194, 2934, 2947, 3146, 3162, 3309, 3440, 3479, 3553, 3569, 3627, 3654, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6652, 6696, 7422, 9370, 9971, 10096, 50507, 83667 GO:0042981 BP e regulation of apoptotic process 44/100 1424/19669 3.2959205582453712e-24 6 44 5.636024154599585e-21 183, 213, 348, 350, 581, 847, 2023, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 9474, 9971, 11035, 50507 GO:0070887 BP e cellular response to chemical stimulus 45/100 1654/19669 1.4606944074211216e-22 3 45 2.2022119915809904e-19 60, 196, 351, 383, 581, 847, 1244, 1440, 2081, 2194, 2876, 2934, 3146, 3162, 3309, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 4851, 5071, 5166, 5468, 5580, 5591, 5663, 6347, 6622, 6649, 6696, 7422, 9370, 9474, 9971, 10096, 11035, 50507, 83667 GO:1901701 BP e cellular response to oxygen-containing compound 34/100 807/19669 1.5740306632482709e-22 4 34 2.2022119915809904e-19 60, 196, 351, 383, 1244, 1440, 2081, 3146, 3309, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 5071, 5166, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 9370, 9971, 11035, 50507, 83667 GO:0006979 BP e response to oxidative stress 25/100 355/19669 7.86802673615306e-22 3 25 1.0090744289116299e-18 348, 351, 383, 847, 1244, 1571, 2081, 2876, 3162, 3569, 4137, 4217, 4313, 4318, 4780, 4831, 5071, 5580, 5663, 6622, 6649, 9370, 11035, 50507, 83667 GO:0065008 BP e regulation of biological quality 61/100 3587/19669 2.4737477604422156e-21 2 61 2.9285367717850534e-18 60, 183, 213, 335, 348, 350, 351, 581, 1152, 1244, 1356, 1401, 1440, 1559, 2081, 2180, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3934, 4137, 4780, 4831, 4846, 4851, 5071, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6696, 7276, 7422, 7450, 9104, 9370, 9474, 9971, 10096, 11035, 83667, 136319, 729230 GO:0043066 BP e negative regulation of apoptotic process 33/100 844/19669 7.751002969492463e-21 7 33 8.520566835749217e-18 213, 348, 350, 581, 847, 2023, 2243, 2876, 2896, 3064, 3162, 3309, 3479, 3553, 3569, 3654, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9474, 9971 GO:0043069 BP e negative regulation of programmed cell death 33/100 861/19669 1.429582890108805e-20 6 33 1.466752045251634e-17 213, 348, 350, 581, 847, 2023, 2243, 2876, 2896, 3064, 3162, 3309, 3479, 3553, 3569, 3654, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9474, 9971 GO:0051716 BP e cellular response to stimulus 54/100 2832/19669 1.7189363985243934e-20 2 54 1.6149262395346148e-17 60, 196, 213, 335, 351, 383, 581, 821, 847, 1244, 1440, 1719, 2081, 2194, 2876, 2934, 3146, 3162, 3309, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6649, 6696, 7422, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 81631, 83667, 136319 GO:0071310 BP e cellular response to organic substance 39/100 1322/19669 1.7838691404865797e-20 4 39 1.6149262395346148e-17 60, 196, 351, 383, 581, 847, 1244, 1440, 2081, 2194, 2934, 3146, 3309, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4313, 4780, 4831, 4851, 5071, 5166, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9370, 9971, 10096, 50507, 83667 GO:0060548 BP e negative regulation of cell death 34/100 949/19669 2.6716638825840945e-20 5 34 2.2842726196094007e-17 213, 348, 350, 581, 847, 1440, 2023, 2243, 2876, 2896, 3064, 3162, 3309, 3479, 3553, 3569, 3654, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5580, 5591, 5663, 6347, 6622, 7422, 9104, 9474, 9971 GO:0080134 BP e regulation of response to stress 39/100 1340/19669 2.873993079383668e-20 4 39 2.3279343943007717e-17 183, 335, 348, 350, 351, 383, 581, 1719, 2023, 2081, 2243, 2876, 2896, 3146, 3309, 3458, 3479, 3553, 3569, 4137, 4217, 4318, 4780, 4846, 5071, 5243, 5327, 5465, 5468, 5580, 5591, 6622, 6696, 7422, 9370, 9971, 23476, 83667, 729230 GO:0009719 BP e response to endogenous stimulus 34/100 969/19669 5.134274487477226e-20 2 34 3.950824218113726e-17 60, 196, 335, 351, 383, 847, 1244, 2947, 3146, 3162, 3309, 3479, 3569, 4137, 4199, 4313, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6652, 6696, 9370, 9971, 50507, 83667 GO:0006082 BP e organic acid metabolic process 31/100 867/19669 2.02002336554588e-18 3 31 1.4803885521786232e-15 229, 383, 1152, 1244, 1559, 1571, 1719, 1737, 2023, 2052, 2180, 2194, 2876, 2944, 3030, 3479, 4143, 4199, 4524, 4846, 4860, 5091, 5465, 5468, 6652, 9104, 9370, 9971, 26061, 50507, 83667 GO:1901698 BP e response to nitrogen compound 31/100 869/19669 2.1569857964120445e-18 3 31 1.5089096093991528e-15 60, 196, 351, 383, 847, 1244, 1571, 1719, 2934, 3309, 3440, 3479, 3569, 4217, 4313, 4318, 4524, 4780, 4831, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 9370, 9971, 50507, 83667 GO:0019752 BP e carboxylic acid metabolic process 30/100 801/19669 2.272580294470608e-18 5 30 1.5206526405175068e-15 229, 383, 1152, 1244, 1559, 1571, 1719, 1737, 2023, 2052, 2180, 2194, 2876, 2944, 3030, 3479, 4143, 4199, 4524, 4846, 5091, 5465, 5468, 6652, 9104, 9370, 9971, 26061, 50507, 83667 GO:0033554 BP e cellular response to stress 40/100 1613/19669 2.3812297042457472e-18 3 40 1.5269635478475857e-15 213, 335, 383, 581, 821, 847, 1719, 2081, 2876, 3146, 3162, 3309, 3569, 3627, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6649, 7422, 9131, 9474, 11035, 23476, 50507, 81631, 83667 GO:0044093 BP e positive regulation of molecular function 41/100 1726/19669 3.5084896248419714e-18 3 41 2.159826213052717e-15 183, 229, 302, 335, 348, 350, 351, 581, 847, 1440, 1719, 2081, 2180, 2896, 2934, 3064, 3146, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4846, 5071, 5243, 5468, 5580, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 11035, 50507, 136319, 729230 GO:0032268 BP e regulation of cellular protein metabolic process 47/100 2372/19669 5.4467216185472165e-18 6 47 3.2240402195939096e-15 60, 183, 302, 335, 348, 351, 581, 1440, 1719, 2023, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 4780, 5071, 5327, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9131, 9370, 9474, 11035, 23476, 50507, 83667, 136319 GO:0043436 BP e oxoacid metabolic process 30/100 834/19669 6.9300488636188325e-18 4 30 3.950127852262734e-15 229, 383, 1152, 1244, 1559, 1571, 1719, 1737, 2023, 2052, 2180, 2194, 2876, 2944, 3030, 3479, 4143, 4199, 4524, 4846, 5091, 5465, 5468, 6652, 9104, 9370, 9971, 26061, 50507, 83667 GO:0031667 BP e response to nutrient levels 23/100 412/19669 7.484343940841003e-18 4 23 4.1137161874836805e-15 213, 335, 348, 383, 847, 2180, 2934, 3162, 3309, 3627, 4217, 4524, 4780, 5166, 5465, 5468, 6652, 6696, 9370, 9474, 9971, 81631, 83667 GO:0032101 BP e regulation of response to external stimulus 32/100 984/19669 7.90302354081049e-18 4 32 4.194052837692187e-15 183, 335, 348, 350, 351, 383, 2243, 2876, 2896, 3146, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 5327, 5465, 5468, 5580, 5591, 6347, 6622, 6696, 7422, 9370, 9971, 23476, 729230 GO:0044281 BP e small molecule metabolic process 39/100 1583/19669 9.44628693689096e-18 2 39 4.8041291972925856e-15 229, 335, 348, 351, 383, 847, 1152, 1244, 1559, 1571, 1719, 1737, 2023, 2052, 2180, 2194, 2876, 2944, 3030, 3479, 4143, 4199, 4524, 4831, 4846, 4860, 5091, 5166, 5465, 5468, 6652, 6888, 7276, 9104, 9370, 9971, 26061, 50507, 83667 GO:0042592 BP e homeostatic process 38/100 1492/19669 9.676933405852512e-18 3 38 4.8041291972925856e-15 60, 213, 335, 348, 351, 581, 1152, 1244, 1356, 2081, 2876, 2896, 3064, 3146, 3162, 3553, 3569, 3627, 3934, 4780, 4831, 4846, 4851, 5071, 5166, 5468, 5591, 5663, 5836, 6347, 6622, 7422, 9104, 9370, 9971, 11035, 83667, 729230 GO:0062197 BP e cellular response to chemical stress 19/100 244/19669 1.6091247127762812e-17 4 19 7.738884165508429e-15 383, 847, 2081, 2876, 3569, 4137, 4217, 4313, 4318, 4780, 4831, 5468, 5580, 6622, 6649, 9474, 11035, 50507, 83667 GO:0009991 BP e response to extracellular stimulus 23/100 433/19669 2.2348526571766123e-17 3 23 1.0422540119378198e-14 213, 335, 348, 383, 847, 2180, 2934, 3162, 3309, 3627, 4217, 4524, 4780, 5166, 5465, 5468, 6652, 6696, 9370, 9474, 9971, 81631, 83667 GO:0010243 BP e response to organonitrogen compound 29/100 801/19669 2.3499016671328337e-17 4 29 1.0636760781521855e-14 60, 196, 351, 383, 847, 1244, 1571, 1719, 2934, 3309, 3479, 3569, 4313, 4318, 4524, 4780, 4831, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 9370, 9971, 50507, 83667 GO:0009607 BP e response to biotic stimulus 34/100 1188/19669 2.7519079291825268e-17 2 34 1.210053229431974e-14 351, 383, 581, 1244, 1401, 1440, 1571, 2023, 2243, 2876, 3075, 3146, 3309, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4217, 4846, 4851, 5468, 5580, 5591, 5836, 6347, 6622, 9370, 9474, 9971, 10383, 11035 GO:0009893 BP e positive regulation of metabolic process 56/100 3619/19669 4.134503053893711e-17 4 56 1.7675000555395615e-14 60, 183, 196, 302, 335, 348, 351, 581, 1401, 1440, 2023, 2081, 2180, 2194, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9971, 10096, 11035, 23476, 50507, 83667, 136319, 729230 GO:0019220 BP e regulation of phosphate metabolic process 38/100 1566/19669 4.873986138526137e-17 6 38 1.9739643861030856e-14 60, 183, 335, 348, 351, 581, 1440, 2023, 2081, 2180, 3064, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4846, 5071, 5166, 5465, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9971, 11035, 23476, 50507, 83667 GO:0051174 BP e regulation of phosphorus metabolic process 38/100 1566/19669 4.873986138526137e-17 5 38 1.9739643861030856e-14 60, 183, 335, 348, 351, 581, 1440, 2023, 2081, 2180, 3064, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4846, 5071, 5166, 5465, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9971, 11035, 23476, 50507, 83667 GO:0051246 BP e regulation of protein metabolic process 47/100 2522/19669 6.37468216386123e-17 5 47 2.5155476538929314e-14 60, 183, 302, 335, 348, 351, 581, 1440, 1719, 2023, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 4780, 5071, 5327, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9131, 9370, 9474, 11035, 23476, 50507, 83667, 136319 GO:0048584 BP e positive regulation of response to stimulus 43/100 2091/19669 7.82180856957904e-17 4 43 3.0094408471455364e-14 60, 183, 335, 348, 350, 351, 383, 581, 847, 1401, 1440, 2081, 2243, 2876, 2896, 3064, 3075, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4318, 4780, 4846, 4851, 5071, 5580, 5591, 5663, 6347, 6622, 7422, 9370, 9971, 10096, 11035, 23476, 729230 GO:0043207 BP e response to external biotic stimulus 33/100 1158/19669 1.0573882933809256e-16 3 33 3.9690745939347423e-14 351, 383, 581, 1244, 1401, 1440, 1571, 2023, 2243, 2876, 3075, 3146, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4217, 4846, 4851, 5468, 5580, 5591, 5836, 6347, 6622, 9370, 9474, 9971, 10383, 11035 GO:0008152 BP e metabolic process 81/100 7950/19669 1.2048247201322572e-16 1 81 4.4148220101989137e-14 60, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1152, 1244, 1356, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2941, 2944, 2947, 3030, 3146, 3162, 3309, 3479, 3553, 3569, 3654, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7450, 9104, 9370, 9474, 9971, 11035, 23476, 26061, 50507, 81631, 83667, 136319 GO:1901564 BP e organonitrogen compound metabolic process 64/100 4942/19669 2.398885113146085e-16 3 64 8.583401748014076e-14 60, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1152, 1244, 1356, 1510, 1559, 1719, 1737, 2023, 2081, 2180, 2194, 2243, 2876, 2934, 2941, 2944, 2947, 3162, 3309, 3479, 3553, 3569, 3654, 4137, 4143, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 7450, 9474, 9971, 11035, 23476, 50507, 136319 GO:0062013 BP e positive regulation of small molecule metabolic process 15/100 135/19669 2.4637069270595543e-16 5 15 8.583401748014076e-14 335, 351, 2023, 3146, 3458, 3479, 3553, 4846, 5465, 5468, 5663, 6622, 9104, 9370, 9971 GO:0034599 BP e cellular response to oxidative stress 17/100 202/19669 2.5097665929865715e-16 5 17 8.583401748014076e-14 383, 847, 2081, 2876, 3569, 4137, 4217, 4313, 4318, 4780, 4831, 5580, 6622, 6649, 11035, 50507, 83667 GO:0002376 BP e immune system process 43/100 2165/19669 2.8039523800957663e-16 1 43 9.381049376016053e-14 60, 302, 351, 383, 581, 821, 847, 1401, 1440, 1510, 2243, 2896, 2934, 3075, 3146, 3162, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4137, 4217, 4318, 4831, 4851, 4860, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 7276, 9474, 9971, 10096, 10383, 11035, 729230 GO:0071704 BP e organic substance metabolic process 78/100 7489/19669 4.356486794590847e-16 2 78 1.4265176972075134e-13 60, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1152, 1244, 1356, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2941, 2944, 2947, 3030, 3146, 3162, 3309, 3479, 3553, 3569, 3654, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6652, 6696, 6888, 7276, 7450, 9104, 9370, 9474, 9971, 11035, 23476, 26061, 50507, 83667, 136319 GO:0032879 BP e regulation of localization 47/100 2651/19669 4.599259465625215e-16 3 47 1.4746375661660848e-13 60, 183, 302, 335, 348, 350, 351, 383, 581, 1244, 1401, 2180, 2243, 2896, 2934, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4137, 4318, 4780, 4846, 4851, 5071, 5243, 5465, 5468, 5580, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9474, 9971, 11035, 50507, 83667, 729230 GO:0032787 BP e monocarboxylic acid metabolic process 23/100 499/19669 4.910584680695323e-16 6 23 1.5423244537938986e-13 229, 1152, 1244, 1559, 1571, 1737, 2023, 2052, 2180, 2194, 2876, 2944, 3030, 3479, 4199, 5091, 5465, 5468, 6652, 9370, 9971, 26061, 83667 GO:0031325 BP e positive regulation of cellular metabolic process 51/100 3156/19669 5.405170879162327e-16 5 51 1.6637115966061646e-13 183, 196, 302, 335, 348, 351, 581, 1401, 1440, 2023, 2081, 2180, 2194, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9131, 9370, 9971, 10096, 11035, 23476, 50507, 83667 GO:0051247 BP e positive regulation of protein metabolic process 36/100 1501/19669 6.39279904475962e-16 6 36 1.9291211235068733e-13 183, 348, 351, 581, 1440, 2023, 2081, 2180, 2896, 2934, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 5071, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9131, 9370, 11035, 23476, 50507, 136319 GO:0032270 BP e positive regulation of cellular protein metabolic process 35/100 1421/19669 8.344899259307682e-16 7 35 2.4697692230912544e-13 183, 348, 351, 581, 1440, 2023, 2081, 2180, 2896, 2934, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 5071, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9131, 9370, 11035, 23476, 50507 GO:0051239 BP e regulation of multicellular organismal process 46/100 2583/19669 9.70543377868734e-16 3 46 2.818238223660342e-13 183, 302, 335, 348, 350, 351, 383, 1401, 1440, 2023, 2180, 2243, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4318, 4780, 4831, 4846, 4851, 4860, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6696, 7422, 9104, 9370, 9474, 9971, 11035, 136319, 729230 GO:0010604 BP e positive regulation of macromolecule metabolic process 52/100 3341/19669 1.1135082511379957e-15 5 52 3.173498515743287e-13 60, 183, 196, 302, 348, 351, 581, 1401, 1440, 2023, 2081, 2180, 2896, 2934, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9971, 10096, 11035, 23476, 50507, 83667, 136319, 729230 GO:0001932 BP e regulation of protein phosphorylation 32/100 1176/19669 1.3086244955946648e-15 8 32 3.661769270400344e-13 60, 183, 335, 348, 351, 581, 1440, 2081, 2180, 3064, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4318, 5071, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 11035, 23476, 50507, 83667 GO:0042325 BP e regulation of phosphorylation 34/100 1363/19669 1.7052231494879718e-15 7 34 4.686318619753551e-13 60, 183, 335, 348, 351, 581, 1440, 2081, 2180, 3064, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 5071, 5465, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 11035, 23476, 50507, 83667 GO:0048583 BP e regulation of response to stimulus 56/100 3926/19669 1.7836418790028258e-15 3 56 4.815833073307629e-13 60, 183, 335, 348, 350, 351, 383, 581, 847, 1401, 1440, 1719, 2023, 2081, 2243, 2876, 2896, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4780, 4846, 4851, 5071, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319, 729230 GO:0043269 BP e regulation of ion transport 33/100 1278/19669 1.8768716204279186e-15 5 33 4.911607478344399e-13 60, 183, 302, 335, 348, 351, 383, 581, 1244, 2180, 2243, 3064, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 5071, 5243, 5465, 5468, 5580, 5663, 6347, 6622, 6696, 9104, 9370, 9474, 9971, 729230 GO:0044237 BP e cellular metabolic process 76/100 7254/19669 1.882942438091745e-15 2 76 4.911607478344399e-13 60, 196, 213, 229, 335, 348, 350, 351, 383, 581, 847, 1152, 1244, 1356, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2941, 2944, 2947, 3030, 3146, 3162, 3309, 3479, 3569, 3654, 4137, 4143, 4199, 4217, 4313, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 9104, 9370, 9474, 9971, 11035, 23476, 26061, 50507, 81631, 83667, 136319 GO:0050727 BP e regulation of inflammatory response 19/100 322/19669 2.7438384076606546e-15 6 19 7.037945515649579e-13 183, 335, 348, 351, 2876, 2896, 3458, 3479, 3553, 3569, 4318, 5465, 5468, 5580, 6622, 9370, 9971, 23476, 729230 GO:0042127 BP e regulation of cell population proliferation 36/100 1579/19669 3.0983588546473318e-15 4 36 7.817007011970892e-13 183, 196, 348, 350, 351, 383, 581, 1401, 1440, 2081, 2876, 2896, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4313, 4318, 4831, 4846, 4851, 4860, 5468, 5591, 6347, 7422, 9104, 9370, 11035, 50507, 729230 GO:0010942 BP e positive regulation of cell death 24/100 609/19669 3.398809451718593e-15 5 24 8.436722171282121e-13 183, 383, 581, 2896, 2934, 3064, 3146, 3162, 3458, 3569, 4137, 4217, 4318, 4851, 5468, 5580, 5591, 5663, 6347, 6622, 9131, 9370, 11035, 50507 GO:0031399 BP e regulation of protein modification process 36/100 1587/19669 3.623542455983849e-15 7 36 8.83728229677116e-13 60, 183, 335, 348, 351, 581, 1440, 2081, 2180, 3064, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 5071, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 11035, 23476, 50507, 83667 GO:0043068 BP e positive regulation of programmed cell death 23/100 548/19669 3.675023177344731e-15 6 23 8.83728229677116e-13 183, 383, 581, 2896, 2934, 3064, 3146, 3162, 3458, 3569, 4217, 4318, 4851, 5468, 5580, 5591, 5663, 6347, 6622, 9131, 9370, 11035, 50507 GO:0051049 BP e regulation of transport 37/100 1687/19669 3.7564259659099386e-15 4 37 8.894060863900608e-13 60, 183, 302, 335, 348, 351, 383, 581, 1244, 2180, 2243, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4851, 5071, 5243, 5465, 5468, 5580, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9474, 9971, 729230 GO:0065009 BP e regulation of molecular function 49/100 3082/19669 5.977702068223309e-15 2 49 1.3938914368175262e-12 60, 183, 229, 302, 335, 348, 350, 351, 581, 847, 1440, 1719, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4846, 4851, 5071, 5243, 5465, 5468, 5580, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 9971, 11035, 50507, 83667, 136319, 729230 GO:0048518 BP e positive regulation of biological process 68/100 5948/19669 7.331067500646095e-15 3 68 1.6839571467902e-12 60, 183, 196, 302, 335, 348, 350, 351, 383, 581, 847, 1401, 1440, 2023, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4217, 4313, 4318, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5243, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 26762, 50507, 83667, 136319, 729230 GO:1905952 BP e regulation of lipid localization 15/100 171/19669 8.785271845785451e-15 4 15 1.988313730979972e-12 183, 302, 335, 348, 1401, 2180, 3553, 3569, 5071, 5465, 5468, 5580, 5663, 6696, 9370 GO:0051093 BP e negative regulation of developmental process 27/100 849/19669 8.951541687085807e-15 4 27 1.996582993684791e-12 302, 350, 351, 1401, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 4137, 4318, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9104, 9370, 729230 GO:0002682 BP e regulation of immune system process 34/100 1455/19669 1.1700003719568743e-14 3 34 2.561520516665916e-12 60, 196, 335, 348, 351, 383, 581, 1401, 1440, 2876, 2896, 3075, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 4831, 4860, 5468, 5580, 5591, 5663, 6347, 7422, 9370, 9474, 10096, 11035, 26762, 729230 GO:0044419 BP e biological process involved in interspecies interaction between organisms 36/100 1649/19669 1.1817281136015595e-14 1 36 2.561520516665916e-12 302, 348, 351, 383, 581, 821, 1401, 1571, 2023, 2243, 2876, 3075, 3146, 3440, 3458, 3569, 3627, 3654, 3934, 4217, 4780, 5071, 5091, 5468, 5580, 5591, 5836, 6347, 9370, 9474, 9971, 10383, 11035, 23476, 26762, 729230 GO:0051128 BP e regulation of cellular component organization 42/100 2296/19669 1.3609153229290635e-14 4 42 2.9089565027608734e-12 183, 302, 335, 348, 351, 581, 1440, 2023, 2876, 2896, 2934, 3064, 3146, 3309, 3458, 3479, 3553, 3569, 3627, 4137, 4318, 4524, 4780, 4831, 4851, 5071, 5465, 5468, 5580, 5663, 6622, 6696, 7422, 7846, 9370, 9474, 9971, 10096, 23476, 50507, 83667, 136319 GO:2000377 BP e regulation of reactive oxygen species metabolic process 15/100 177/19669 1.4701068457603182e-14 5 15 3.0953293008179882e-12 183, 1401, 1719, 3458, 3553, 4137, 4780, 5071, 5465, 5580, 6622, 9104, 9474, 11035, 50507 GO:0048585 BP e negative regulation of response to stimulus 35/100 1563/19669 1.4883324773263882e-14 4 35 3.0953293008179882e-12 183, 335, 348, 350, 383, 581, 2023, 2243, 2876, 2896, 3064, 3162, 3309, 3440, 3479, 3553, 3569, 4318, 4780, 4846, 4851, 5071, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 9370, 9971, 83667, 729230 GO:0014070 BP e response to organic cyclic compound 25/100 724/19669 1.6772739045746053e-14 4 25 3.424597722098708e-12 60, 196, 351, 383, 847, 1244, 1719, 2180, 2934, 3146, 3309, 3440, 3553, 3569, 3627, 4524, 4851, 5071, 5468, 6347, 6622, 6696, 9370, 9971, 50507 GO:0043270 BP e positive regulation of ion transport 24/100 655/19669 1.6911593689376335e-14 6 24 3.424597722098708e-12 60, 302, 335, 348, 581, 2180, 2243, 3064, 3458, 3479, 3553, 3627, 4780, 5243, 5580, 5663, 6347, 6622, 6696, 9104, 9370, 9474, 9971, 729230 GO:0051050 BP e positive regulation of transport 27/100 875/19669 1.8576891169465532e-14 5 27 3.712965650624344e-12 60, 302, 335, 348, 581, 2180, 2243, 3064, 3458, 3479, 3553, 3627, 4780, 5071, 5243, 5468, 5580, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9474, 9971, 729230 GO:0000302 BP e response to reactive oxygen species 15/100 180/19669 1.888246258184066e-14 4 15 3.72565511710933e-12 348, 383, 847, 1571, 2081, 2876, 3162, 3569, 4137, 4217, 4313, 4318, 4780, 5580, 11035 GO:0043065 BP e positive regulation of apoptotic process 22/100 534/19669 2.331124074701556e-14 7 22 4.5412657607160675e-12 183, 581, 2896, 2934, 3064, 3146, 3162, 3458, 3569, 4217, 4318, 4851, 5468, 5580, 5591, 5663, 6347, 6622, 9131, 9370, 11035, 50507 GO:0140352 BP e export from cell 28/100 965/19669 2.526345782409152e-14 4 28 4.8600576989096056e-12 213, 302, 335, 350, 351, 383, 821, 847, 1244, 2243, 2896, 2934, 3146, 3479, 3569, 3934, 4318, 4831, 4860, 5243, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0045055 BP e regulated exocytosis 24/100 670/19669 2.7763508032233326e-14 7 24 5.275066526124332e-12 213, 302, 335, 350, 351, 383, 847, 2243, 2896, 2934, 3146, 3479, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0062012 BP e regulation of small molecule metabolic process 20/100 421/19669 2.899181501429905e-14 4 20 5.4412686959763705e-12 335, 348, 351, 2023, 2194, 3146, 3458, 3479, 3553, 4846, 5071, 5166, 5465, 5468, 5663, 6622, 9104, 9370, 9971, 83667 GO:0051240 BP e positive regulation of multicellular organismal process 32/100 1334/19669 4.429485748819439e-14 4 32 8.213227189678453e-12 183, 302, 348, 350, 351, 2023, 2180, 2243, 2896, 3146, 3162, 3458, 3479, 3553, 3569, 3654, 3934, 4137, 4780, 4831, 4846, 4851, 4860, 5468, 5591, 5663, 7422, 9370, 9474, 9971, 136319, 729230 GO:0006807 BP e nitrogen compound metabolic process 70/100 6537/19669 5.954457438790238e-14 2 70 1.0909416664640688e-11 60, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1152, 1244, 1356, 1510, 1559, 1571, 1719, 1737, 2023, 2081, 2180, 2194, 2243, 2876, 2934, 2941, 2944, 2947, 3146, 3162, 3309, 3479, 3553, 3569, 3654, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 7450, 9474, 9971, 11035, 23476, 50507, 83667, 136319 GO:0031331 BP e positive regulation of cellular catabolic process 19/100 382/19669 6.057729586142056e-14 6 19 1.0968053921261912e-11 335, 348, 351, 581, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 4780, 5071, 5465, 5580, 5663, 6622, 9104, 83667 GO:0010035 BP e response to inorganic substance 21/100 502/19669 7.322669151478046e-14 3 21 1.310417188851711e-11 351, 383, 847, 1571, 2081, 2243, 2876, 2934, 3162, 3309, 3569, 4137, 4217, 4318, 4780, 5071, 5580, 6622, 6649, 6652, 11035 GO:0030162 BP e regulation of proteolysis 24/100 709/19669 9.515174545002885e-14 6 24 1.683201566064303e-11 183, 302, 348, 351, 581, 2023, 2876, 2896, 2934, 3146, 3458, 3553, 4137, 4217, 4318, 4780, 5071, 5327, 5468, 5663, 6622, 7422, 9104, 9131 GO:0032102 BP e negative regulation of response to external stimulus 18/100 350/19669 1.6882425724892284e-13 5 18 2.952506044387412e-11 335, 348, 350, 383, 2243, 2876, 2896, 3479, 4846, 4851, 5327, 5465, 5468, 5580, 6347, 6696, 9370, 9971 GO:0051241 BP e negative regulation of multicellular organismal process 27/100 961/19669 1.756477109657161e-13 4 27 3.0373239008565956e-11 335, 348, 350, 383, 2243, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 4831, 4846, 4851, 5327, 5465, 5468, 5580, 5663, 6696, 9104, 9370, 9971, 729230 GO:0051707 BP e response to other organism 27/100 966/19669 1.9870116284721625e-13 4 27 3.3977898846873983e-11 351, 383, 581, 1401, 1571, 2023, 2243, 2876, 3075, 3146, 3440, 3458, 3569, 3627, 3654, 3934, 4217, 5468, 5580, 5591, 5836, 6347, 9370, 9474, 9971, 10383, 11035 GO:0045937 BP e positive regulation of phosphate metabolic process 27/100 968/19669 2.087048202425585e-13 7 27 3.4912686777532326e-11 183, 351, 1440, 2023, 2081, 2180, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4846, 5465, 5580, 5663, 6622, 7422, 9104, 9370, 9971, 11035, 50507 GO:0010562 BP e positive regulation of phosphorus metabolic process 27/100 968/19669 2.087048202425585e-13 6 27 3.4912686777532326e-11 183, 351, 1440, 2023, 2081, 2180, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4846, 5465, 5580, 5663, 6622, 7422, 9104, 9370, 9971, 11035, 50507 GO:0051173 BP e positive regulation of nitrogen compound metabolic process 46/100 2980/19669 2.142596299050221e-13 5 46 3.545651294879881e-11 183, 196, 348, 351, 581, 1440, 2023, 2081, 2180, 2896, 2934, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9131, 9370, 9971, 10096, 11035, 23476, 50507, 83667, 136319 GO:0045862 BP e positive regulation of proteolysis 18/100 358/19669 2.480617003089701e-13 8 18 4.061350603994733e-11 348, 351, 581, 2023, 2896, 2934, 3146, 3458, 3553, 4137, 4217, 4780, 5071, 5468, 5663, 6622, 9104, 9131 GO:0009891 BP e positive regulation of biosynthetic process 37/100 1931/19669 2.545244320280772e-13 5 37 4.1232957988548496e-11 183, 196, 335, 348, 351, 1440, 2023, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9971, 10096, 11035, 23476, 83667, 136319 GO:1902531 BP e regulation of intracellular signal transduction 35/100 1726/19669 2.816688736378692e-13 6 35 4.515504130507091e-11 183, 335, 348, 351, 581, 847, 1440, 2023, 2081, 2243, 2876, 3064, 3146, 3162, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 4851, 5071, 5465, 5580, 5663, 6347, 7422, 9104, 9370, 9971, 11035, 23476, 83667 GO:0032368 BP e regulation of lipid transport 13/100 140/19669 2.864776159102741e-13 7 13 4.5452479472774405e-11 183, 302, 335, 348, 2180, 3553, 5071, 5465, 5468, 5580, 5663, 6696, 9370 GO:0044070 BP e regulation of anion transport 25/100 823/19669 2.984629613585405e-13 6 25 4.687086709497896e-11 60, 183, 302, 335, 348, 383, 1244, 2180, 2243, 3458, 3479, 3553, 3569, 4780, 5071, 5243, 5465, 5468, 5580, 5663, 6622, 6696, 9370, 9474, 9971 GO:0006887 BP e exocytosis 24/100 749/19669 3.1123007909488297e-13 6 24 4.838213047747727e-11 213, 302, 335, 350, 351, 383, 847, 2243, 2896, 2934, 3146, 3479, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0048878 BP e chemical homeostasis 28/100 1073/19669 3.4357718328727433e-13 4 28 5.287652850791152e-11 335, 348, 351, 581, 1152, 1244, 1356, 2081, 2896, 3064, 3146, 3162, 3569, 3627, 3934, 4831, 5071, 5166, 5468, 5663, 5836, 6622, 7422, 9104, 9370, 9971, 83667, 729230 GO:0019725 BP e cellular homeostasis 25/100 831/19669 3.700354906237939e-13 4 25 5.638461584851672e-11 348, 351, 581, 1152, 1244, 1356, 2081, 2876, 2896, 3064, 3146, 3162, 3569, 3627, 3934, 4780, 4831, 4846, 5071, 5663, 6347, 6622, 9104, 9971, 729230 GO:0001775 BP e cell activation 27/100 999/19669 4.402453010515289e-13 2 27 6.606627830028432e-11 302, 351, 383, 581, 847, 2896, 2934, 3146, 3440, 3458, 3479, 3569, 3627, 3934, 4137, 4318, 4831, 4860, 5580, 5591, 5663, 5836, 6622, 7276, 7450, 10383, 11035 GO:0032940 BP e secretion by cell 26/100 917/19669 4.4215897757825126e-13 5 26 6.606627830028432e-11 213, 302, 335, 350, 351, 383, 821, 847, 2243, 2896, 2934, 3146, 3479, 3569, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0023056 BP e positive regulation of signaling 34/100 1666/19669 5.84591276302119e-13 4 34 8.542549327919772e-11 183, 302, 335, 348, 351, 581, 847, 1440, 2081, 2243, 2876, 3064, 3146, 3162, 3479, 3553, 3569, 3654, 4217, 4318, 4846, 4851, 5071, 5580, 5663, 6347, 6622, 6696, 7422, 9370, 9971, 11035, 23476, 729230 GO:0050790 BP e regulation of catalytic activity 41/100 2441/19669 5.847662260760512e-13 3 41 8.542549327919772e-11 60, 183, 229, 302, 335, 348, 350, 351, 581, 1719, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3458, 3479, 3553, 3627, 3654, 4137, 4217, 4318, 4846, 4851, 5071, 5468, 5580, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 11035, 50507, 83667, 729230 GO:0051130 BP e positive regulation of cellular component organization 28/100 1097/19669 5.883757171926548e-13 5 28 8.542549327919772e-11 183, 302, 335, 348, 351, 581, 1440, 2876, 2896, 2934, 3064, 3309, 3458, 3479, 3553, 3569, 4137, 4318, 4780, 4831, 5071, 5468, 5663, 6622, 7422, 10096, 23476, 50507 GO:0043085 BP e positive regulation of catalytic activity 31/100 1386/19669 7.971061754972157e-13 4 31 1.1464919664394531e-10 183, 229, 335, 348, 350, 351, 581, 1719, 2081, 2180, 2896, 2934, 3146, 3458, 3479, 3553, 3654, 4137, 4217, 4846, 5468, 5580, 5663, 6347, 6622, 7422, 9104, 9131, 9370, 11035, 50507 GO:0046903 BP e secretion 27/100 1028/19669 8.637054010942681e-13 4 27 1.2261624893100643e-10 213, 302, 335, 350, 351, 383, 821, 847, 1244, 2243, 2896, 2934, 3146, 3479, 3569, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0044238 BP e primary metabolic process 71/100 7004/19669 8.684321724158352e-13 2 71 1.2261624893100643e-10 60, 213, 229, 302, 335, 348, 350, 351, 383, 581, 847, 1356, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2934, 2944, 3030, 3146, 3309, 3479, 3569, 3654, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6652, 6696, 6888, 7276, 7450, 9104, 9370, 9474, 9971, 11035, 23476, 26061, 50507, 83667 GO:0048522 BP e positive regulation of cellular process 62/100 5409/19669 9.23146829615032e-13 4 62 1.291566337070486e-10 183, 196, 302, 335, 348, 351, 383, 581, 847, 1401, 1440, 2023, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 4846, 4851, 4860, 5071, 5243, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9971, 10096, 11035, 23476, 26762, 50507, 83667, 136319, 729230 GO:0009896 BP e positive regulation of catabolic process 19/100 447/19669 9.900454347427285e-13 5 19 1.3726846162784316e-10 335, 348, 351, 581, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 4780, 5071, 5465, 5580, 5663, 6622, 9104, 83667 GO:0009628 BP e response to abiotic stimulus 27/100 1036/19669 1.0360555420044409e-12 2 27 1.4236513206650308e-10 351, 581, 847, 1244, 2876, 2934, 3162, 3309, 3479, 3553, 3627, 3654, 4137, 4313, 4318, 4524, 4846, 5465, 5468, 5580, 5591, 6649, 6652, 7422, 9370, 50507, 136319 GO:0031347 BP e regulation of defense response 22/100 647/19669 1.1067559738920577e-12 5 22 1.5073428706370591e-10 183, 335, 348, 351, 383, 2876, 2896, 3146, 3458, 3479, 3553, 3569, 4318, 5465, 5468, 5580, 5591, 6622, 9370, 9971, 23476, 729230 GO:1901699 BP e cellular response to nitrogen compound 19/100 456/19669 1.4058069319188053e-12 4 19 1.8978393580903867e-10 60, 196, 351, 383, 3309, 3479, 4217, 4313, 4780, 5071, 5468, 5580, 5591, 5663, 6622, 9370, 9971, 50507, 83667 GO:0043549 BP e regulation of kinase activity 25/100 884/19669 1.44988207248106e-12 8 25 1.940320443085523e-10 60, 183, 348, 351, 2081, 2180, 3064, 3146, 3458, 3479, 3553, 3627, 3654, 4137, 4217, 5071, 5580, 5663, 6622, 7422, 9104, 9370, 11035, 50507, 83667 GO:0050793 BP e regulation of developmental process 40/100 2393/19669 1.5229844534102548e-12 3 40 2.0205802360330878e-10 183, 302, 335, 348, 350, 351, 581, 1401, 1440, 2243, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 4137, 4217, 4318, 4780, 4831, 4846, 4851, 4860, 5071, 5465, 5468, 5591, 5663, 6347, 6696, 7422, 9104, 9370, 9971, 136319, 729230 GO:0048660 BP e regulation of smooth muscle cell proliferation 12/100 125/19669 1.6603610945953108e-12 5 12 2.1840134398138315e-10 2081, 3162, 3458, 3479, 3569, 3654, 4217, 4313, 4318, 5468, 5591, 9370 GO:0034764 BP e positive regulation of transmembrane transport 14/100 203/19669 2.010695487007502e-12 6 14 2.6003868525248277e-10 581, 2180, 3064, 3458, 3479, 3627, 4780, 5243, 5663, 6347, 6622, 9104, 9370, 729230 GO:0034767 BP e positive regulation of ion transmembrane transport 14/100 203/19669 2.010695487007502e-12 7 14 2.6003868525248277e-10 581, 2180, 3064, 3458, 3479, 3627, 4780, 5243, 5663, 6347, 6622, 9104, 9370, 729230 GO:0051338 BP e regulation of transferase activity 26/100 989/19669 2.466632415064309e-12 4 26 3.1634560723199764e-10 60, 183, 348, 351, 2081, 2180, 3064, 3146, 3458, 3479, 3553, 3627, 3654, 4137, 4217, 5071, 5468, 5580, 5663, 6622, 7422, 9104, 9370, 11035, 50507, 83667 GO:0051098 BP e regulation of binding 17/100 354/19669 2.5505962792282705e-12 3 17 3.2358424246771686e-10 60, 302, 348, 351, 581, 1440, 3146, 3162, 3458, 3479, 4318, 5071, 5465, 5468, 5580, 5663, 9370 GO:0009725 BP e response to hormone 21/100 604/19669 2.5651252489318684e-12 4 21 3.2358424246771686e-10 335, 383, 847, 1244, 2947, 3146, 3162, 3569, 4199, 4780, 4831, 4846, 4851, 5465, 5468, 5580, 5591, 6652, 6696, 9370, 83667 GO:0071495 BP e cellular response to endogenous stimulus 22/100 679/19669 2.873922697686864e-12 3 22 3.5959081558862473e-10 60, 196, 351, 383, 1244, 3309, 3479, 4137, 4313, 4780, 4851, 5071, 5468, 5580, 5591, 5663, 6347, 6622, 9370, 9971, 50507, 83667 GO:0071417 BP e cellular response to organonitrogen compound 18/100 416/19669 3.1182107462328167e-12 5 18 3.870101885848632e-10 60, 196, 351, 383, 3309, 3479, 4313, 4780, 5071, 5468, 5580, 5591, 5663, 6622, 9370, 9971, 50507, 83667 GO:2000145 BP e regulation of cell motility 25/100 923/19669 3.729870178810706e-12 5 25 4.5922161641517414e-10 183, 348, 350, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 5468, 6347, 7422, 9104, 9370, 11035, 50507, 729230 GO:0022407 BP e regulation of cell-cell adhesion 18/100 423/19669 4.119569141128821e-12 5 18 5.031759450950201e-10 335, 383, 2243, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4851, 4860, 5465, 5580, 6347, 7422, 9370, 729230 GO:0031328 BP e positive regulation of cellular biosynthetic process 35/100 1899/19669 4.482540852472835e-12 6 35 5.43199241886275e-10 183, 196, 335, 348, 351, 1440, 2023, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9971, 10096, 11035, 23476, 83667 GO:1901652 BP e response to peptide 17/100 367/19669 4.530734770823473e-12 5 17 5.447500634607284e-10 351, 383, 847, 1244, 3479, 4313, 4318, 4780, 4831, 4851, 5465, 5468, 5580, 5591, 5663, 9370, 83667 GO:0044092 BP e negative regulation of molecular function 27/100 1105/19669 4.656615142351448e-12 3 27 5.55545015820068e-10 60, 183, 302, 335, 348, 351, 581, 847, 2876, 3162, 3458, 3553, 3654, 4137, 4318, 4851, 5071, 5465, 5468, 5580, 5663, 6622, 7422, 9104, 9370, 9971, 729230 GO:0045859 BP e regulation of protein kinase activity 23/100 775/19669 5.0852049052720516e-12 9 23 6.020100268625914e-10 60, 183, 348, 351, 2081, 2180, 3064, 3146, 3458, 3479, 3553, 3627, 3654, 4217, 5580, 5663, 6622, 7422, 9104, 9370, 11035, 50507, 83667 GO:0030334 BP e regulation of cell migration 24/100 861/19669 6.021409209465066e-12 6 24 7.074006697226516e-10 183, 348, 350, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 5468, 6347, 7422, 9370, 11035, 50507, 729230 GO:0002252 BP e immune effector process 25/100 948/19669 6.669690782658834e-12 2 25 7.776253117054504e-10 60, 302, 351, 383, 847, 1401, 2896, 2934, 3075, 3146, 3440, 3458, 3569, 3627, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10096, 10383, 11035 GO:0042493 BP e response to drug 16/100 323/19669 7.485080166180756e-12 3 16 8.661307049437731e-10 335, 383, 847, 1244, 2180, 3162, 3309, 3553, 4524, 4780, 4860, 5243, 5468, 6652, 9370, 9474 GO:0050678 BP e regulation of epithelial cell proliferation 16/100 324/19669 7.84191813236031e-12 5 16 9.006501496792922e-10 348, 350, 383, 581, 2876, 2896, 3146, 3162, 3479, 4831, 4851, 5468, 5591, 6347, 7422, 9104 GO:0040012 BP e regulation of locomotion 25/100 963/19669 9.370987831497075e-12 3 25 1.0682926127906666e-09 183, 348, 350, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 5468, 6347, 7422, 9104, 9370, 11035, 50507, 729230 GO:0048523 BP e negative regulation of cellular process 56/100 4755/19669 9.479333028248372e-12 4 56 1.0726980537113415e-09 183, 196, 213, 302, 335, 348, 350, 351, 383, 581, 847, 1401, 1440, 1719, 2023, 2081, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4318, 4780, 4831, 4846, 4851, 5071, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9474, 9971, 50507, 83667, 729230 GO:0033993 BP e response to lipid 22/100 722/19669 9.573774114988676e-12 4 22 1.0754772527713556e-09 196, 383, 847, 1244, 1440, 2180, 3146, 3553, 3569, 3627, 3654, 4831, 4846, 4851, 5166, 5465, 5468, 6347, 6622, 6696, 9370, 9971 GO:0045935 BP e positive regulation of nucleobase-containing compound metabolic process 34/100 1845/19669 1.0279559660124364e-11 6 34 1.1463943707921303e-09 183, 196, 348, 351, 581, 1440, 2023, 2081, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6696, 7422, 9971, 10096, 11035, 23476, 83667 GO:0045321 BP e leukocyte activation 24/100 884/19669 1.0462303369048396e-11 3 24 1.1583802075514732e-09 302, 351, 383, 581, 847, 2896, 2934, 3146, 3440, 3458, 3569, 3934, 4137, 4318, 4831, 4860, 5580, 5591, 5663, 5836, 6622, 7276, 10383, 11035 GO:2001233 BP e regulation of apoptotic signaling pathway 16/100 336/19669 1.3546777110134654e-11 7 16 1.489177855178374e-09 183, 581, 2023, 2243, 2876, 3064, 3162, 3479, 3553, 4318, 4780, 4846, 5071, 5580, 5663, 11035 GO:1902533 BP e positive regulation of intracellular signal transduction 25/100 983/19669 1.4604209266330763e-11 7 25 1.5940339050271663e-09 183, 335, 348, 351, 581, 847, 1440, 2081, 2243, 2876, 3146, 3162, 3479, 3553, 3569, 3654, 4217, 4851, 5071, 5663, 6347, 7422, 9370, 11035, 23476 GO:0010647 BP e positive regulation of cell communication 32/100 1659/19669 1.584233781042995e-11 5 32 1.716997034524767e-09 183, 335, 348, 351, 581, 847, 1440, 2081, 2243, 2876, 3064, 3146, 3162, 3479, 3553, 3569, 3654, 4217, 4318, 4846, 4851, 5071, 5580, 5663, 6347, 6696, 7422, 9370, 9971, 11035, 23476, 729230 GO:0051270 BP e regulation of cellular component movement 25/100 991/19669 1.7387866553789992e-11 4 25 1.8713235402994966e-09 183, 348, 350, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 5468, 6347, 7422, 9104, 9370, 11035, 50507, 729230 GO:0019222 BP e regulation of metabolic process 67/100 6706/19669 2.0142791946626084e-11 3 67 2.1527608892956627e-09 60, 183, 196, 302, 335, 348, 351, 383, 581, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2180, 2194, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4199, 4217, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5091, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 83667, 136319, 729230 GO:0006952 BP e defense response 27/100 1181/19669 2.1502668278742252e-11 3 27 2.2753763567857593e-09 351, 383, 1244, 1401, 2243, 3075, 3146, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4217, 4780, 4851, 5468, 5580, 5591, 6347, 6696, 9971, 10383, 11035, 50507, 729230 GO:0007584 BP e response to nutrient 12/100 155/19669 2.1585766607584198e-11 5 12 2.2753763567857593e-09 335, 383, 847, 2180, 2934, 3162, 3627, 4524, 5468, 6696, 9370, 9971 GO:0031329 BP e regulation of cellular catabolic process 23/100 842/19669 2.7094401554709297e-11 5 23 2.836617958686912e-09 302, 335, 348, 351, 581, 2081, 2876, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 4137, 4780, 5071, 5465, 5580, 5663, 6622, 9104, 83667 GO:0001817 BP e regulation of cytokine production 21/100 685/19669 2.7313830628664628e-11 6 21 2.840269279561814e-09 183, 335, 351, 383, 1401, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3654, 5465, 5591, 5663, 9370, 9474, 9971, 11035, 729230 GO:0071900 BP e regulation of protein serine/threonine kinase activity 18/100 481/19669 3.446831454911196e-11 10 18 3.5601836302740473e-09 60, 183, 348, 2081, 2180, 3064, 3458, 3479, 3553, 3627, 3654, 4217, 5580, 5663, 6622, 7422, 9370, 83667 GO:0010629 BP e negative regulation of gene expression 24/100 937/19669 3.510588230393096e-11 6 24 3.586080106100329e-09 335, 348, 351, 383, 1244, 1719, 2081, 3146, 3162, 3440, 3458, 3479, 3569, 4137, 4851, 5071, 5091, 5465, 5591, 5663, 7422, 9370, 9971, 83667 GO:0050865 BP e regulation of cell activation 19/100 549/19669 3.5185061469860284e-11 4 19 3.586080106100329e-09 196, 348, 383, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 4846, 4860, 5580, 5591, 6347, 11035, 26762, 729230 GO:0009967 BP e positive regulation of signal transduction 30/100 1505/19669 3.743607752170019e-11 6 30 3.766487916131354e-09 183, 335, 348, 351, 581, 847, 1440, 2081, 2243, 2876, 3064, 3146, 3162, 3479, 3553, 3569, 3654, 4217, 4318, 4846, 4851, 5071, 5580, 5663, 6347, 7422, 9370, 9971, 11035, 23476 GO:0034762 BP e regulation of transmembrane transport 19/100 551/19669 3.74446167100778e-11 5 19 3.766487916131354e-09 60, 351, 581, 2180, 3064, 3458, 3479, 3553, 3627, 4318, 4780, 5243, 5663, 6347, 6622, 9104, 9370, 9474, 729230 GO:0051094 BP e positive regulation of developmental process 27/100 1217/19669 4.2590839245371055e-11 4 27 4.256318285625069e-09 183, 335, 348, 581, 1440, 2243, 2896, 3146, 3162, 3458, 3479, 3553, 3569, 4137, 4217, 4780, 4831, 4846, 4851, 4860, 5071, 5468, 5591, 5663, 7422, 9370, 9971 GO:2000379 BP e positive regulation of reactive oxygen species metabolic process 10/100 94/19669 4.626500183082973e-11 6 10 4.593666955977223e-09 183, 1401, 3458, 3553, 4137, 4780, 5580, 6622, 11035, 50507 GO:0009968 BP e negative regulation of signal transduction 27/100 1226/19669 5.0331979932732414e-11 6 27 4.965443404902255e-09 183, 335, 348, 383, 581, 2023, 2243, 2876, 3064, 3162, 3309, 3479, 3553, 3569, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6622, 9370, 9971, 83667 GO:0009056 BP e catabolic process 34/100 1958/19669 5.270392214088752e-11 2 34 5.166327144893369e-09 229, 302, 348, 383, 847, 1244, 1559, 1571, 2023, 2052, 2081, 2180, 2876, 2944, 2947, 3030, 3146, 3162, 3309, 4143, 4313, 4318, 4780, 4846, 4860, 5071, 5836, 6652, 6696, 9370, 9474, 26061, 81631, 83667 GO:0048519 BP e negative regulation of biological process 58/100 5230/19669 5.6899064972374095e-11 3 58 5.5422570248407435e-09 183, 196, 213, 302, 335, 348, 350, 351, 383, 581, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2243, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4318, 4780, 4831, 4846, 4851, 5071, 5091, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9474, 9971, 50507, 83667, 729230 GO:0009966 BP e regulation of signal transduction 42/100 2949/19669 6.32434291975625e-11 5 42 6.121486637424445e-09 183, 335, 348, 351, 383, 581, 847, 1440, 2023, 2081, 2243, 2876, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6347, 6622, 7422, 9104, 9370, 9971, 11035, 23476, 83667, 729230 GO:0051341 BP e regulation of oxidoreductase activity 10/100 98/19669 7.048136246431913e-11 4 10 6.7794260520366965e-09 183, 348, 1719, 3458, 3553, 4846, 5071, 6622, 9104, 11035 GO:0030335 BP e positive regulation of cell migration 18/100 505/19669 7.634384739981763e-11 7 18 7.297713114802442e-09 183, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 7422, 50507, 729230 GO:0060255 BP e regulation of macromolecule metabolic process 63/100 6174/19669 7.964010952305714e-11 4 63 7.565810404690429e-09 60, 183, 196, 302, 335, 348, 351, 383, 581, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5091, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 83667, 136319, 729230 GO:2001234 BP e negative regulation of apoptotic signaling pathway 13/100 218/19669 8.096916157627447e-11 8 13 7.64487973410346e-09 581, 2023, 2243, 2876, 3064, 3162, 3479, 3553, 4318, 4780, 4846, 5071, 5663 GO:0002274 BP e myeloid leukocyte activation 19/100 580/19669 8.976039105557158e-11 4 19 8.423246453324674e-09 302, 351, 383, 847, 2896, 2934, 3146, 3458, 3934, 4137, 4318, 4831, 4860, 5580, 5663, 5836, 6622, 7276, 10383 GO:0009058 BP e biosynthetic process 37/100 2363/19669 1.0622374914395275e-10 2 37 9.907778783790505e-09 229, 335, 348, 383, 581, 1152, 1559, 1571, 1719, 1737, 2023, 2180, 2194, 2876, 2941, 2944, 2947, 3479, 3553, 4143, 4199, 4524, 4831, 4846, 4851, 4860, 5091, 5130, 5465, 5468, 5836, 6622, 6652, 6888, 9104, 9971, 50507 GO:0010632 BP e regulation of epithelial cell migration 13/100 227/19669 1.3394952839772126e-10 7 13 1.2418573747234521e-08 183, 348, 350, 2896, 3146, 3162, 3458, 4318, 4780, 4846, 4851, 5468, 7422 GO:0080090 BP e regulation of primary metabolic process 60/100 5736/19669 1.4435013667041156e-10 4 60 1.3302686247650504e-08 60, 183, 196, 302, 335, 348, 351, 581, 847, 1440, 1719, 2023, 2081, 2180, 2194, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4199, 4217, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 83667, 136319 GO:1904705 BP e regulation of vascular associated smooth muscle cell proliferation 8/100 50/19669 1.5116763462554107e-10 6 8 1.3848035100518317e-08 2081, 3162, 3479, 4217, 4313, 4318, 5468, 9370 GO:2000147 BP e positive regulation of cell motility 18/100 527/19669 1.5247742085923555e-10 6 18 1.388536986404518e-08 183, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 7422, 50507, 729230 GO:0008219 BP e cell death 22/100 841/19669 1.8028541923353488e-10 2 22 1.6321132952965306e-08 196, 351, 581, 2934, 3064, 3162, 3309, 3440, 3458, 3553, 3569, 3934, 4217, 4851, 5580, 5591, 5663, 5836, 6622, 9131, 9474, 11035 GO:0071496 BP e cellular response to external stimulus 14/100 285/19669 1.895779698867205e-10 3 14 1.7062017289804845e-08 213, 3162, 3309, 3553, 4217, 4780, 5166, 5465, 5468, 9474, 9971, 81631, 83667, 136319 GO:0045834 BP e positive regulation of lipid metabolic process 11/100 146/19669 2.0742814125195671e-10 6 11 1.8559994731788454e-08 183, 335, 348, 3458, 3553, 5465, 5468, 5580, 9104, 9370, 9971 GO:0051272 BP e positive regulation of cellular component movement 18/100 539/19669 2.1930609205419647e-10 5 18 1.9509368535919563e-08 183, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 7422, 50507, 729230 GO:0042542 BP e response to hydrogen peroxide 10/100 110/19669 2.2447424956433515e-10 5 10 1.9854360349397232e-08 383, 847, 2081, 2876, 3162, 3569, 4217, 4780, 5580, 11035 GO:0040017 BP e positive regulation of locomotion 18/100 540/19669 2.2595446015723674e-10 4 18 1.987108081039928e-08 183, 351, 2896, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4846, 4851, 7422, 50507, 729230 GO:2000026 BP e regulation of multicellular organismal development 27/100 1312/19669 2.3085393729325068e-10 4 27 2.0186602812176863e-08 350, 1440, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 4137, 4318, 4780, 4831, 4846, 4851, 4860, 5465, 5468, 5591, 5663, 6696, 7422, 9104, 9370, 729230 GO:0010648 BP e negative regulation of cell communication 27/100 1314/19669 2.3882240260721166e-10 5 27 2.076540551483044e-08 183, 335, 348, 383, 581, 2023, 2243, 2876, 3064, 3162, 3309, 3479, 3553, 3569, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6622, 9370, 9971, 83667 GO:0023051 BP e regulation of signaling 44/100 3347/19669 2.428100462264225e-10 3 44 2.095506636530724e-08 183, 302, 335, 348, 351, 383, 581, 847, 1440, 2023, 2081, 2243, 2876, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9971, 11035, 23476, 83667, 729230 GO:0010628 BP e positive regulation of gene expression 24/100 1030/19669 2.43726892747888e-10 6 24 2.095506636530724e-08 60, 183, 351, 1401, 2023, 2081, 2934, 3146, 3162, 3458, 3479, 3553, 3569, 3654, 4780, 4846, 4851, 5071, 5468, 5591, 5663, 7422, 9370, 729230 GO:0034614 BP e cellular response to reactive oxygen species 10/100 111/19669 2.456716125161403e-10 6 10 2.100492287013e-08 383, 2081, 3569, 4137, 4217, 4313, 4318, 4780, 5580, 11035 GO:0006955 BP e immune response 24/100 1031/19669 2.4856839391992007e-10 2 24 2.113518001341199e-08 351, 383, 1401, 1440, 2243, 3075, 3146, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4217, 4851, 4860, 5468, 5580, 5591, 6347, 9971, 10383, 729230 GO:0023057 BP e negative regulation of signaling 27/100 1317/19669 2.5126340553584407e-10 4 27 2.1246944017563963e-08 183, 335, 348, 383, 581, 2023, 2243, 2876, 3064, 3162, 3309, 3479, 3553, 3569, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6622, 9370, 9971, 83667 GO:1903793 BP e positive regulation of anion transport 17/100 476/19669 2.643298877823416e-10 7 17 2.2175201909313453e-08 60, 302, 335, 348, 2180, 2243, 3458, 3479, 3553, 4780, 5243, 5580, 5663, 6696, 9370, 9474, 9971 GO:0051129 BP e negative regulation of cellular component organization 20/100 695/19669 2.6512262191771764e-10 5 20 2.2175201909313453e-08 335, 348, 2876, 2934, 3146, 3309, 3479, 3553, 3627, 4137, 4851, 5071, 5580, 5663, 6622, 6696, 7422, 9370, 9474, 9971 GO:0034765 BP e regulation of ion transmembrane transport 18/100 546/19669 2.6993754451139597e-10 6 18 2.2455885459623697e-08 351, 581, 2180, 3064, 3458, 3479, 3553, 3627, 4318, 4780, 5243, 5663, 6347, 6622, 9104, 9370, 9474, 729230 GO:0031401 BP e positive regulation of protein modification process 24/100 1036/19669 2.7416187878641056e-10 8 24 2.2684684486682036e-08 183, 351, 1440, 2081, 2180, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3654, 4217, 4318, 5071, 5580, 5663, 6622, 7422, 9370, 11035, 23476, 50507 GO:0043393 BP e regulation of protein binding 12/100 194/19669 2.9671900543001997e-10 4 12 2.4419815473625712e-08 60, 302, 348, 351, 581, 1440, 4318, 5071, 5465, 5580, 5663, 9370 GO:0002263 BP e cell activation involved in immune response 19/100 623/19669 3.001591020953781e-10 3 19 2.45715350066376e-08 302, 351, 383, 847, 2896, 2934, 3146, 3440, 3458, 3569, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0071407 BP e cellular response to organic cyclic compound 15/100 354/19669 3.1800133037092585e-10 5 15 2.589439404448968e-08 60, 196, 351, 383, 1244, 3309, 3553, 5071, 5468, 6347, 6622, 6696, 9370, 9971, 50507 GO:0051353 BP e positive regulation of oxidoreductase activity 8/100 55/19669 3.357588262960142e-10 5 8 2.719646492997716e-08 183, 348, 1719, 3458, 3553, 6622, 9104, 11035 GO:0045596 BP e negative regulation of cell differentiation 19/100 628/19669 3.4321279058364847e-10 5 19 2.7654685063258383e-08 351, 1401, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 4318, 4780, 4831, 4851, 5465, 5468, 5663, 6696, 7422, 9370 GO:0031669 BP e cellular response to nutrient levels 12/100 198/19669 3.7548479624171157e-10 5 12 3.00974531987497e-08 213, 3162, 3309, 4217, 4780, 5166, 5465, 5468, 9474, 9971, 81631, 83667 GO:0045595 BP e regulation of cell differentiation 29/100 1555/19669 4.22949099439394e-10 4 29 3.3566711065997614e-08 183, 335, 351, 1401, 1440, 2243, 2896, 3146, 3440, 3458, 3479, 3553, 3569, 3627, 4137, 4217, 4318, 4780, 4831, 4851, 4860, 5465, 5468, 5591, 5663, 6696, 7422, 9370, 729230 GO:0007165 BP e signal transduction 53/100 4728/19669 4.2312813169613613e-10 4 53 3.3566711065997614e-08 60, 183, 196, 302, 335, 348, 351, 581, 821, 1244, 1440, 2081, 2180, 2243, 2896, 2934, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4217, 4313, 4318, 4780, 4831, 4846, 4851, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6696, 6888, 7276, 7422, 9131, 9370, 9971, 10096, 11035, 83667, 729230 GO:0051171 BP e regulation of nitrogen compound metabolic process 58/100 5539/19669 4.3048259110728377e-10 4 58 3.397501065200563e-08 60, 183, 196, 302, 335, 348, 351, 581, 847, 1440, 1719, 2023, 2081, 2180, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 83667, 136319 GO:0032370 BP e positive regulation of lipid transport 9/100 85/19669 4.705365978260717e-10 8 9 3.6877075972680386e-08 302, 335, 348, 2180, 3553, 5580, 5663, 6696, 9370 GO:0008284 BP e positive regulation of cell population proliferation 22/100 885/19669 4.720457418205351e-10 5 22 3.6877075972680386e-08 183, 383, 1440, 2081, 2896, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4313, 4318, 4831, 4851, 4860, 5591, 7422, 729230 GO:0098754 BP e detoxification 10/100 119/19669 4.904798515791715e-10 1 10 3.8123661190926526e-08 213, 348, 847, 2876, 2944, 2947, 4780, 4846, 6649, 83667 GO:0006109 BP e regulation of carbohydrate metabolic process 12/100 203/19669 5.00314362917181e-10 5 12 3.869265349394681e-08 351, 3146, 3458, 3479, 5071, 5166, 5465, 5663, 6622, 9104, 9370, 83667 GO:0012501 BP e programmed cell death 21/100 804/19669 5.161460565952383e-10 3 21 3.97174390550036e-08 196, 351, 581, 2934, 3064, 3309, 3440, 3458, 3553, 3569, 3934, 4217, 4851, 5580, 5591, 5663, 5836, 6622, 9131, 9474, 11035 GO:0042327 BP e positive regulation of phosphorylation 22/100 894/19669 5.707022686155714e-10 8 22 4.3697054298475844e-08 183, 351, 1440, 2081, 2180, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 5580, 5663, 6622, 7422, 9370, 11035, 50507 GO:0001934 BP e positive regulation of protein phosphorylation 21/100 810/19669 5.903323335883987e-10 9 21 4.497630996992801e-08 183, 351, 1440, 2081, 2180, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4217, 4318, 5580, 5663, 6622, 7422, 9370, 11035, 50507 GO:0060627 BP e regulation of vesicle-mediated transport 17/100 503/19669 6.14696113958395e-10 5 17 4.660183839320049e-08 302, 335, 348, 2243, 3146, 3162, 3458, 3553, 4851, 5071, 5468, 6347, 6622, 7422, 9370, 9474, 729230 GO:0002684 BP e positive regulation of immune system process 22/100 899/19669 6.335331961947544e-10 4 22 4.779448965410427e-08 60, 351, 383, 581, 1401, 3075, 3146, 3162, 3458, 3479, 3553, 3569, 3627, 4860, 5580, 5591, 5663, 6347, 7422, 10096, 26762, 729230 GO:0010557 BP e positive regulation of macromolecule biosynthetic process 31/100 1802/19669 6.405817483135576e-10 6 31 4.8090502958759297e-08 183, 196, 348, 351, 1440, 3146, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6347, 6696, 7422, 9971, 10096, 11035, 23476, 83667, 136319 GO:0010646 BP e regulation of cell communication 43/100 3311/19669 6.613477264626847e-10 4 43 4.9408453933304454e-08 183, 335, 348, 351, 383, 581, 847, 1440, 2023, 2081, 2243, 2876, 3064, 3146, 3162, 3309, 3458, 3479, 3553, 3569, 3654, 4137, 4217, 4318, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9971, 11035, 23476, 83667, 729230 GO:0051649 BP e establishment of localization in cell 35/100 2278/19669 7.147179563477653e-10 3 35 5.3137726319768643e-08 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 2243, 2896, 2934, 3064, 3146, 3309, 3479, 3934, 4137, 4318, 4831, 4860, 5071, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 7846, 9131, 10096, 10383, 26061 GO:0009894 BP e regulation of catabolic process 23/100 999/19669 7.85525155749508e-10 4 23 5.812130839896602e-08 302, 335, 348, 351, 581, 2081, 2876, 3064, 3146, 3162, 3458, 3479, 3553, 3569, 4137, 4780, 5071, 5465, 5580, 5663, 6622, 9104, 83667 GO:0050728 BP e negative regulation of inflammatory response 10/100 125/19669 7.974244256011305e-10 7 10 5.8719434976083265e-08 335, 348, 2876, 2896, 3479, 5465, 5468, 5580, 9370, 9971 GO:0010594 BP e regulation of endothelial cell migration 11/100 166/19669 8.215122394097851e-10 8 11 6.020511125960282e-08 183, 348, 350, 2896, 3146, 3162, 4780, 4846, 4851, 5468, 7422 GO:0031323 BP e regulation of cellular metabolic process 60/100 5945/19669 9.200149865819701e-10 4 60 6.710441063268494e-08 60, 183, 196, 302, 335, 348, 351, 581, 847, 1401, 1440, 1719, 2023, 2081, 2180, 2194, 2876, 2896, 2934, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4318, 4524, 4780, 4831, 4846, 4851, 5071, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9131, 9370, 9474, 9971, 10096, 11035, 23476, 50507, 83667, 136319 GO:0051248 BP e negative regulation of protein metabolic process 23/100 1008/19669 9.341569611189803e-10 6 23 6.781450769632597e-08 183, 302, 348, 351, 581, 1719, 2876, 3458, 3479, 3553, 4137, 4318, 5071, 5327, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 83667 GO:0071396 BP e cellular response to lipid 15/100 383/19669 9.411459709257076e-10 5 15 6.80011102936462e-08 196, 383, 1244, 1440, 3146, 3553, 3569, 3627, 3654, 4831, 5166, 5468, 6347, 6696, 9971 GO:1901576 BP e organic substance biosynthetic process 35/100 2306/19669 9.941838959092763e-10 3 35 7.149761756095217e-08 229, 335, 348, 383, 581, 1152, 1559, 1571, 1719, 1737, 2023, 2180, 2194, 2876, 2941, 2944, 2947, 3479, 3553, 4143, 4199, 4524, 4831, 4851, 4860, 5091, 5130, 5465, 5468, 5836, 6622, 6652, 6888, 9104, 9971 GO:0051099 BP e positive regulation of binding 11/100 170/19669 1.0584102339590186e-09 4 11 7.576248139827583e-08 302, 348, 351, 1440, 3146, 3458, 3479, 4318, 5071, 5468, 5663 GO:0031668 BP e cellular response to extracellular stimulus 12/100 217/19669 1.0739448745917715e-09 4 12 7.651857231466373e-08 213, 3162, 3309, 4217, 4780, 5166, 5465, 5468, 9474, 9971, 81631, 83667 GO:0019216 BP e regulation of lipid metabolic process 15/100 387/19669 1.085087492604313e-09 5 15 7.695620512064693e-08 183, 335, 348, 2180, 2194, 3458, 3553, 4199, 5166, 5465, 5468, 5580, 9104, 9370, 9971 GO:0019221 BP e cytokine-mediated signaling pathway 19/100 676/19669 1.169814510083941e-09 6 19 8.258461151464152e-08 302, 821, 1440, 2180, 3162, 3440, 3458, 3553, 3569, 3627, 3654, 3934, 4313, 4318, 5580, 6347, 6888, 7422, 729230 GO:0022603 BP e regulation of anatomical structure morphogenesis 22/100 933/19669 1.2656535977457107e-09 4 22 8.894250625254106e-08 183, 335, 350, 2243, 2896, 3146, 3162, 3553, 3569, 3627, 4137, 4780, 4846, 4851, 5071, 5468, 5591, 5663, 6347, 6696, 7422, 729230 GO:0032409 BP e regulation of transporter activity 13/100 275/19669 1.414239028209016e-09 3 13 9.893244838243982e-08 60, 351, 3064, 3458, 4318, 5243, 5468, 5580, 6347, 6622, 9104, 9370, 729230 GO:0034097 BP e response to cytokine 17/100 534/19669 1.5220319808875196e-09 4 17 1.0599127685909019e-07 351, 383, 1244, 1440, 2194, 2934, 3146, 3309, 3553, 3654, 4217, 4524, 4780, 6347, 6622, 9370, 10096 GO:0044087 BP e regulation of cellular component biogenesis 22/100 944/19669 1.5729193264156015e-09 4 22 1.0904156952043293e-07 183, 335, 348, 351, 581, 1440, 2934, 3064, 3146, 3309, 3458, 3553, 4137, 4851, 5071, 5580, 6622, 7422, 9474, 10096, 50507, 136319 GO:0043086 BP e negative regulation of catalytic activity 20/100 771/19669 1.6029799132503634e-09 4 20 1.1062717876647129e-07 183, 302, 335, 348, 351, 2876, 3458, 3553, 4137, 4318, 4851, 5071, 5468, 5580, 5663, 6622, 7422, 9104, 9370, 729230 GO:0032269 BP e negative regulation of cellular protein metabolic process 22/100 947/19669 1.668078832954792e-09 7 22 1.1460595196059933e-07 183, 302, 348, 351, 581, 1719, 2876, 3458, 3553, 4137, 4318, 5071, 5327, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 83667 GO:0031099 BP e regeneration 10/100 136/19669 1.8252664504265187e-09 3 10 1.248482252091739e-07 335, 1719, 2876, 2934, 3162, 3569, 4851, 5468, 9104, 136319 GO:0032496 BP e response to lipopolysaccharide 13/100 282/19669 1.918607897433953e-09 5 13 1.3065210416596698e-07 383, 1244, 1440, 3146, 3553, 3569, 3627, 3654, 4846, 4851, 6347, 6622, 9971 GO:0002366 BP e leukocyte activation involved in immune response 18/100 619/19669 1.9893543355163997e-09 4 18 1.3487296574271978e-07 302, 383, 847, 2896, 2934, 3146, 3440, 3458, 3569, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0032501 BP e multicellular organismal process 43/100 3438/19669 2.19502887995434e-09 1 43 1.4816444939691796e-07 183, 196, 213, 335, 348, 351, 383, 581, 1244, 1401, 1440, 1737, 2243, 2876, 2934, 3064, 3146, 3162, 3440, 3479, 3553, 3569, 3627, 4137, 4313, 4318, 4846, 4851, 4860, 5071, 5243, 5327, 5465, 5591, 5663, 6347, 7422, 7450, 9370, 9474, 9971, 50507, 729230 GO:0050776 BP e regulation of immune response 21/100 873/19669 2.258208834060029e-09 4 21 1.5176346705757138e-07 60, 348, 383, 581, 1401, 2876, 2896, 3075, 3146, 3162, 3440, 3458, 3553, 3569, 5468, 5580, 5591, 5663, 10096, 11035, 729230 GO:0051254 BP e positive regulation of RNA metabolic process 29/100 1673/19669 2.3050033625268518e-09 7 29 1.5423479021429678e-07 183, 196, 348, 351, 1440, 2081, 3146, 3309, 3440, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9971, 10096, 11035, 23476, 83667 GO:0010605 BP e negative regulation of macromolecule metabolic process 38/100 2764/19669 2.332213681777597e-09 5 38 1.553799504872607e-07 183, 196, 302, 335, 348, 351, 383, 581, 1244, 1719, 2023, 2081, 2876, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 4137, 4318, 4851, 5071, 5091, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 9971, 83667 GO:0050818 BP e regulation of coagulation 8/100 70/19669 2.445578718352409e-09 4 8 1.6175304470505385e-07 348, 350, 2243, 4780, 4846, 5327, 5580, 5663 GO:0010038 BP e response to metal ion 14/100 347/19669 2.4488927495956822e-09 4 14 1.6175304470505385e-07 351, 383, 847, 2243, 2934, 3162, 3309, 4137, 4318, 4780, 5071, 6622, 6649, 6652 GO:0030155 BP e regulation of cell adhesion 19/100 709/19669 2.5641628015667554e-09 4 19 1.686430150261212e-07 335, 383, 2243, 2934, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4851, 4860, 5465, 5580, 6347, 7422, 9370, 729230 GO:0071216 BP e cellular response to biotic stimulus 11/100 185/19669 2.590023602175814e-09 3 11 1.696189924999395e-07 383, 1244, 1440, 3146, 3309, 3553, 3569, 3627, 3654, 6347, 9971 GO:0055082 BP e cellular chemical homeostasis 19/100 711/19669 2.685295730235284e-09 5 19 1.7511314105220775e-07 348, 351, 581, 1152, 1244, 1356, 2081, 2896, 3064, 3146, 3162, 3627, 3934, 4831, 5663, 6622, 9104, 9971, 729230 GO:0045981 BP e positive regulation of nucleotide metabolic process 7/100 45/19669 2.749085292101715e-09 8 7 1.7776648170355205e-07 351, 2023, 3458, 3479, 4846, 5465, 5663 GO:1900544 BP e positive regulation of purine nucleotide metabolic process 7/100 45/19669 2.749085292101715e-09 9 7 1.7776648170355205e-07 351, 2023, 3458, 3479, 4846, 5465, 5663 GO:0045893 BP e positive regulation of transcription, DNA-templated 28/100 1579/19669 2.8664363087809423e-09 10 28 1.83810228300578e-07 183, 196, 348, 351, 1440, 3146, 3309, 3440, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9971, 10096, 11035, 23476, 83667 GO:1903508 BP e positive regulation of nucleic acid-templated transcription 28/100 1579/19669 2.8664363087809423e-09 9 28 1.83810228300578e-07 183, 196, 348, 351, 1440, 3146, 3309, 3440, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9971, 10096, 11035, 23476, 83667 GO:1902680 BP e positive regulation of RNA biosynthetic process 28/100 1580/19669 2.907072378918239e-09 8 28 1.8564250585706104e-07 183, 196, 348, 351, 1440, 3146, 3309, 3440, 3479, 3553, 3569, 3627, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9971, 10096, 11035, 23476, 83667 GO:1990748 BP e cellular detoxification 9/100 105/19669 3.1590967441773836e-09 2 9 2.009028879871485e-07 213, 348, 847, 2876, 2944, 2947, 4846, 6649, 83667 GO:0010638 BP e positive regulation of organelle organization 17/100 565/19669 3.5516994360945007e-09 6 17 2.249409642859851e-07 302, 335, 581, 1440, 2896, 2934, 3064, 3479, 3553, 4137, 4318, 5071, 6622, 7422, 10096, 23476, 50507 GO:0046890 BP e regulation of lipid biosynthetic process 11/100 191/19669 3.6234966672119195e-09 6 11 2.285475971655387e-07 335, 348, 2194, 3458, 3553, 5166, 5465, 5580, 9104, 9370, 9971 GO:1901214 BP e regulation of neuron death 13/100 298/19669 3.735834189340195e-09 5 13 2.346713803018188e-07 348, 581, 1440, 2896, 3162, 3458, 4137, 4217, 5071, 5465, 5663, 6347, 6622 GO:1902903 BP e regulation of supramolecular fiber organization 14/100 359/19669 3.784943425425326e-09 5 14 2.3678975332234053e-07 335, 348, 351, 1440, 2876, 2934, 4137, 5071, 5580, 5663, 6622, 10096, 50507, 136319 GO:0009611 BP e response to wounding 11/100 192/19669 3.827711346574851e-09 3 11 2.384958608250484e-07 335, 383, 581, 1719, 2934, 3162, 3479, 4217, 5465, 7450, 729230 GO:1905954 BP e positive regulation of lipid localization 9/100 108/19669 4.060721130434608e-09 5 9 2.519939443443089e-07 302, 335, 348, 2180, 3553, 5580, 5663, 6696, 9370 GO:0006629 BP e lipid metabolic process 24/100 1188/19669 4.194929115730919e-09 3 24 2.592769441409592e-07 335, 348, 350, 351, 581, 847, 1559, 1571, 2052, 2180, 2194, 2876, 2944, 3030, 5091, 5130, 5465, 5468, 6696, 7276, 9370, 9971, 26061, 83667 GO:0002237 BP e response to molecule of bacterial origin 13/100 301/19669 4.214077586973082e-09 4 13 2.5941861625406296e-07 383, 1244, 1440, 3146, 3553, 3569, 3627, 3654, 4846, 4851, 6347, 6622, 9971 GO:0045913 BP e positive regulation of carbohydrate metabolic process 8/100 75/19669 4.280450101089126e-09 6 8 2.624546894651859e-07 351, 3146, 3458, 3479, 5465, 5663, 6622, 9104 GO:0007154 BP e cell communication 20/100 817/19669 4.309598685405371e-09 2 20 2.631933482872566e-07 183, 213, 348, 3162, 3309, 3440, 3553, 3627, 4137, 4217, 4780, 5071, 5166, 5465, 5468, 6622, 9474, 9971, 81631, 83667 GO:0071222 BP e cellular response to lipopolysaccharide 10/100 150/19669 4.736932418068194e-09 6 10 2.881477862216186e-07 383, 1244, 1440, 3146, 3553, 3569, 3627, 3654, 6347, 9971 GO:0052547 BP e regulation of peptidase activity 15/100 432/19669 4.833659964017255e-09 7 15 2.928741214418329e-07 183, 302, 351, 581, 2876, 2896, 2934, 3146, 4137, 4217, 4318, 5468, 6622, 7422, 9131 GO:0006915 BP e apoptotic process 18/100 657/19669 5.057541750292236e-09 4 18 3.0523751975293145e-07 196, 351, 581, 2934, 3064, 3309, 3440, 3458, 3553, 3569, 3934, 4217, 4851, 5580, 5663, 6622, 9131, 9474 GO:1903034 BP e regulation of response to wounding 10/100 152/19669 5.3849625173952695e-09 5 10 3.237288013387235e-07 348, 350, 2243, 2896, 3146, 4780, 4846, 5327, 5580, 6696 GO:0043281 BP e regulation of cysteine-type endopeptidase activity involved in apoptotic process 11/100 199/19669 5.570175411720438e-09 10 11 3.322674402572773e-07 581, 2876, 2934, 3146, 4137, 4217, 4318, 5468, 6622, 7422, 9131 GO:0031348 BP e negative regulation of defense response 11/100 199/19669 5.570175411720438e-09 6 11 3.322674402572773e-07 335, 348, 383, 2876, 2896, 3479, 5465, 5468, 5580, 9370, 9971 GO:0009892 BP e negative regulation of metabolic process 39/100 2993/19669 6.043101697158792e-09 4 39 3.5908623598175213e-07 183, 196, 302, 335, 348, 351, 383, 581, 1244, 1719, 2023, 2081, 2876, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 4137, 4318, 4851, 5071, 5091, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 9971, 83667 GO:0002694 BP e regulation of leukocyte activation 16/100 512/19669 6.3271897158897014e-09 5 16 3.745209604905481e-07 196, 383, 2896, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 4860, 5591, 6347, 11035, 26762, 729230 GO:0050730 BP e regulation of peptidyl-tyrosine phosphorylation 12/100 254/19669 6.375525519483846e-09 9 12 3.759361599419785e-07 183, 351, 1440, 3440, 3458, 3479, 3569, 5580, 5663, 7422, 9370, 50507 GO:0009987 BP e cellular process 97/100 14867/19669 6.4125561456823505e-09 1 97 3.766764850459976e-07 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1440, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 2941, 2944, 2947, 3030, 3064, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7422, 7450, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 50507, 81631, 83667, 136319, 729230 GO:0080135 BP e regulation of cellular response to stress 18/100 669/19669 6.701213772342583e-09 5 18 3.921356652332789e-07 351, 581, 1719, 2023, 2081, 2876, 2896, 3146, 3309, 3553, 4137, 4217, 4780, 5071, 5580, 5591, 6696, 7422 GO:0016192 BP e vesicle-mediated transport 28/100 1647/19669 7.276327006068831e-09 4 28 4.236626594606118e-07 213, 302, 335, 348, 350, 351, 383, 821, 847, 2243, 2896, 2934, 3064, 3146, 3479, 3934, 4318, 4831, 4860, 5071, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 10383 GO:0033674 BP e positive regulation of kinase activity 17/100 593/19669 7.295036046592731e-09 9 17 4.236626594606118e-07 183, 2081, 2180, 3146, 3458, 3479, 3553, 3654, 4137, 4217, 5580, 5663, 6622, 7422, 9370, 11035, 50507 GO:0006631 BP e fatty acid metabolic process 13/100 316/19669 7.546366004208564e-09 7 13 4.366111759577813e-07 1559, 1571, 2052, 2180, 2194, 2876, 2944, 3030, 5465, 5468, 9370, 26061, 83667 GO:0042326 BP e negative regulation of phosphorylation 14/100 380/19669 7.80289115391243e-09 8 14 4.49762153028885e-07 183, 348, 581, 3458, 3553, 4137, 5071, 5465, 5580, 5591, 5663, 6622, 9104, 9370 GO:0045860 BP e positive regulation of protein kinase activity 16/100 520/19669 7.876084222709492e-09 10 16 4.522870753264891e-07 183, 2081, 2180, 3146, 3458, 3479, 3553, 3654, 4217, 5580, 5663, 6622, 7422, 9370, 11035, 50507 GO:0046889 BP e positive regulation of lipid biosynthetic process 8/100 81/19669 7.959132575819732e-09 7 8 4.536705568217248e-07 335, 348, 3458, 3553, 5465, 5580, 9104, 9971 GO:0048661 BP e positive regulation of smooth muscle cell proliferation 8/100 81/19669 7.959132575819732e-09 6 8 4.536705568217248e-07 2081, 3162, 3479, 3569, 3654, 4217, 4313, 4318 GO:0002275 BP e myeloid cell activation involved in immune response 16/100 521/19669 8.092400525186368e-09 5 16 4.5956473831224446e-07 302, 383, 847, 2896, 2934, 3146, 3458, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0051345 BP e positive regulation of hydrolase activity 19/100 763/19669 8.4656239403446e-09 5 19 4.789924722128801e-07 229, 335, 350, 351, 581, 2896, 2934, 3146, 3458, 4137, 4217, 5468, 5580, 6347, 6622, 7422, 9104, 9131, 11035 GO:0051046 BP e regulation of secretion 17/100 601/19669 8.895082185260792e-09 5 17 5.014480396745919e-07 183, 348, 1244, 2243, 3162, 3458, 3479, 3553, 3569, 4851, 5071, 6622, 6696, 9370, 9474, 9971, 729230 GO:0043408 BP e regulation of MAPK cascade 18/100 682/19669 9.028846965515408e-09 7 18 5.071312218951902e-07 183, 348, 351, 2081, 2243, 3146, 3479, 3553, 3569, 3654, 4217, 4851, 5071, 5580, 5663, 6347, 7422, 9370 GO:1901360 BP e organic cyclic compound metabolic process 39/100 3038/19669 9.262258969215716e-09 3 39 5.183496928590177e-07 229, 335, 348, 351, 581, 847, 1244, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2876, 2944, 2947, 3146, 3162, 4137, 4199, 4524, 4780, 4831, 4851, 4860, 5071, 5091, 5465, 5468, 5591, 6622, 6696, 7276, 9971, 83667, 136319 GO:0071219 BP e cellular response to molecule of bacterial origin 10/100 161/19669 9.3793578950349e-09 5 10 5.230011521905331e-07 383, 1244, 1440, 3146, 3553, 3569, 3627, 3654, 6347, 9971 GO:0006805 BP e xenobiotic metabolic process 9/100 119/19669 9.590825972749008e-09 3 9 5.328621361754774e-07 196, 1244, 1559, 1571, 2052, 2180, 2941, 2944, 2947 GO:0032642 BP e regulation of chemokine production 8/100 84/19669 1.0653765824904751e-08 7 8 5.876754696963588e-07 351, 3146, 3162, 3458, 3553, 3569, 9370, 9971 GO:0002718 BP e regulation of cytokine production involved in immune response 8/100 84/19669 1.0653765824904751e-08 7 8 5.876754696963588e-07 335, 383, 3162, 3440, 3553, 3569, 9474, 729230 GO:0006954 BP e inflammatory response 15/100 460/19669 1.1217768620851722e-08 4 15 6.165766395532429e-07 1244, 1401, 3146, 3440, 3458, 3553, 3569, 3627, 4780, 4851, 6347, 6696, 9971, 50507, 729230 GO:0010468 BP e regulation of gene expression 51/100 4779/19669 1.1524096160489172e-08 5 51 6.311595726331971e-07 60, 183, 196, 335, 348, 351, 383, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2876, 2934, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4137, 4217, 4780, 4831, 4846, 4851, 5071, 5091, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9370, 9474, 9971, 10096, 11035, 23476, 83667, 136319, 729230 GO:0045765 BP e regulation of angiogenesis 12/100 268/19669 1.161172406979044e-08 6 12 6.3370366465984e-07 350, 2896, 3146, 3162, 3553, 3569, 3627, 4780, 4846, 5468, 7422, 729230 GO:0098771 BP e inorganic ion homeostasis 18/100 694/19669 1.181826419555444e-08 6 18 6.426964168536496e-07 348, 351, 581, 1152, 1244, 1356, 2896, 3064, 3146, 3162, 3627, 3934, 5071, 5166, 5663, 6622, 9104, 729230 GO:0044283 BP e small molecule biosynthetic process 16/100 540/19669 1.3388940083819612e-08 3 16 7.255485489083938e-07 229, 335, 1559, 1571, 1719, 2023, 2194, 2876, 2944, 4524, 4831, 4860, 5091, 6652, 6888, 9104 GO:0098542 BP e defense response to other organism 19/100 786/19669 1.3655393394272473e-08 5 19 7.368277590805741e-07 351, 383, 1401, 2243, 3075, 3146, 3440, 3458, 3569, 3627, 3654, 3934, 4217, 5468, 5580, 5591, 9971, 10383, 11035 GO:1901342 BP e regulation of vasculature development 12/100 272/19669 1.3692835548865769e-08 5 12 7.368277590805741e-07 350, 2896, 3146, 3162, 3553, 3569, 3627, 4780, 4846, 5468, 7422, 729230 GO:0002697 BP e regulation of immune effector process 14/100 399/19669 1.4449730377094802e-08 4 14 7.748479111619826e-07 335, 383, 2896, 3075, 3146, 3162, 3440, 3458, 3553, 3569, 5591, 9474, 11035, 729230 GO:0051336 BP e regulation of hydrolase activity 24/100 1270/19669 1.5330536129694063e-08 4 24 8.192255244305265e-07 183, 229, 302, 335, 350, 351, 581, 2876, 2896, 2934, 3064, 3146, 3458, 4137, 4217, 4318, 5468, 5580, 6347, 6622, 7422, 9104, 9131, 11035 GO:0043535 BP e regulation of blood vessel endothelial cell migration 8/100 89/19669 1.6903629895928544e-08 9 8 9.00162159509828e-07 348, 3146, 3162, 4780, 4846, 4851, 5468, 7422 GO:0060284 BP e regulation of cell development 15/100 475/19669 1.7191424668297522e-08 5 15 9.12331122914134e-07 335, 2243, 2896, 3458, 3479, 3553, 3569, 4137, 4851, 5468, 5591, 5663, 6696, 7422, 9370 GO:0052548 BP e regulation of endopeptidase activity 14/100 405/19669 1.7431459988343503e-08 8 14 9.218906158783728e-07 183, 302, 351, 581, 2876, 2934, 3146, 4137, 4217, 4318, 5468, 6622, 7422, 9131 GO:0050764 BP e regulation of phagocytosis 8/100 90/19669 1.84756478519831e-08 6 8 9.737678782260956e-07 335, 3146, 3458, 3553, 5468, 6347, 9370, 9474 GO:0051348 BP e negative regulation of transferase activity 12/100 280/19669 1.8888407388439e-08 5 12 9.92124879549748e-07 183, 348, 3458, 3553, 4137, 5071, 5468, 5580, 5663, 6622, 9104, 9370 GO:2000116 BP e regulation of cysteine-type endopeptidase activity 11/100 224/19669 1.9044772638006272e-08 9 11 9.969355472752262e-07 581, 2876, 2934, 3146, 4137, 4217, 4318, 5468, 6622, 7422, 9131 GO:0010660 BP e regulation of muscle cell apoptotic process 7/100 59/19669 1.950207806941057e-08 7 7 1.0139762888115833e-06 350, 3162, 3458, 3479, 4217, 4780, 5468 GO:0032722 BP e positive regulation of chemokine production 7/100 59/19669 1.950207806941057e-08 8 7 1.0139762888115833e-06 351, 3146, 3162, 3458, 3553, 3569, 9370 GO:0003013 BP e circulatory system process 12/100 281/19669 1.9649030862950108e-08 3 12 1.0181770538074146e-06 183, 348, 1244, 1401, 2243, 2876, 3627, 4846, 5243, 7422, 9474, 50507 GO:0043312 BP e neutrophil degranulation 15/100 482/19669 2.0869534337926512e-08 9 15 1.0777923941633857e-06 302, 383, 847, 2896, 2934, 3146, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0002283 BP e neutrophil activation involved in immune response 15/100 486/19669 2.32802896512985e-08 7 15 1.1982731027875715e-06 302, 383, 847, 2896, 2934, 3146, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0002521 BP e leukocyte differentiation 12/100 287/19669 2.4819314806658106e-08 4 12 1.2732308495815609e-06 1440, 2194, 3146, 3440, 3458, 3569, 4318, 5468, 5591, 5663, 7422, 11035 GO:0048143 BP e astrocyte activation 5/100 18/19669 2.496474931485916e-08 3 5 1.2764368503511045e-06 351, 2896, 3458, 4137, 5663 GO:0045923 BP e positive regulation of fatty acid metabolic process 6/100 36/19669 2.5547228071969468e-08 7 6 1.301893510025199e-06 335, 3553, 5465, 5468, 9104, 9370 GO:0070301 BP e cellular response to hydrogen peroxide 7/100 62/19669 2.7766704179877675e-08 7 7 1.410328638047252e-06 383, 2081, 3569, 4217, 4780, 5580, 11035 GO:0032103 BP e positive regulation of response to external stimulus 15/100 494/19669 2.8878958715332512e-08 5 15 1.4619972849637084e-06 183, 350, 351, 383, 2896, 3146, 3458, 3553, 3569, 3627, 5580, 5591, 6622, 7422, 729230 GO:0042119 BP e neutrophil activation 15/100 495/19669 2.9658939612242033e-08 6 15 1.4965609201062454e-06 302, 383, 847, 2896, 2934, 3146, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0050801 BP e ion homeostasis 18/100 742/19669 3.2884236054885175e-08 5 18 1.6530242811731375e-06 348, 351, 581, 1152, 1244, 1356, 2896, 3064, 3146, 3162, 3627, 3934, 5071, 5166, 5663, 6622, 9104, 729230 GO:0036230 BP e granulocyte activation 15/100 499/19669 3.2974558435357584e-08 5 15 1.6530242811731375e-06 302, 383, 847, 2896, 2934, 3146, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:1902905 BP e positive regulation of supramolecular fiber organization 10/100 185/19669 3.535452879754933e-08 6 10 1.7665785655658578e-06 335, 348, 351, 1440, 2876, 2934, 4137, 5663, 10096, 50507 GO:0043299 BP e leukocyte degranulation 15/100 503/19669 3.6624429419729375e-08 8 15 1.8241099312933173e-06 302, 383, 847, 2896, 2934, 3146, 3934, 4318, 4831, 4860, 5580, 5663, 5836, 7276, 10383 GO:0044248 BP e cellular catabolic process 27/100 1661/19669 3.741367560813429e-08 3 27 1.8574079600296344e-06 383, 847, 1244, 1559, 1571, 2052, 2081, 2180, 2876, 2944, 2947, 3030, 3146, 3162, 3309, 4143, 4780, 4846, 4860, 5071, 5836, 6652, 9370, 9474, 26061, 81631, 83667 GO:0032680 BP e regulation of tumor necrosis factor production 9/100 140/19669 3.977638620938866e-08 8 9 1.968355574799008e-06 351, 3146, 3458, 3479, 3569, 5663, 9370, 9971, 729230 GO:0008285 BP e negative regulation of cell population proliferation 17/100 667/19669 4.0862469743597406e-08 5 17 2.015619901775526e-06 348, 350, 351, 383, 581, 1401, 3162, 3458, 3553, 3569, 4846, 4851, 5468, 6347, 9104, 9370, 50507 GO:1903580 BP e positive regulation of ATP metabolic process 6/100 39/19669 4.226934094615122e-08 5 6 2.073796273389589e-06 351, 2023, 3458, 3479, 5465, 5663 GO:0010675 BP e regulation of cellular carbohydrate metabolic process 9/100 141/19669 4.2311372959345744e-08 6 9 2.073796273389589e-06 3146, 3479, 5071, 5166, 5465, 6622, 9104, 9370, 83667 GO:0030193 BP e regulation of blood coagulation 7/100 66/19669 4.324778325956503e-08 7 7 2.11296312496732e-06 348, 350, 2243, 4780, 4846, 5327, 5580 GO:0051347 BP e positive regulation of transferase activity 17/100 671/19669 4.4556027497377546e-08 5 17 2.1699913391919e-06 183, 2081, 2180, 3146, 3458, 3479, 3553, 3654, 4137, 4217, 5580, 5663, 6622, 7422, 9370, 11035, 50507 GO:0043410 BP e positive regulation of MAPK cascade 15/100 512/19669 4.621793583067325e-08 8 15 2.2438297553124955e-06 183, 348, 351, 2081, 2243, 3146, 3479, 3553, 3569, 3654, 4217, 4851, 5663, 6347, 7422 GO:0010952 BP e positive regulation of peptidase activity 10/100 191/19669 4.7820091397089793e-08 9 10 2.314311970444062e-06 351, 581, 2896, 2934, 3146, 4137, 4217, 5468, 6622, 9131 GO:1900046 BP e regulation of hemostasis 7/100 67/19669 4.8093752182843656e-08 4 7 2.3202597056237117e-06 348, 350, 2243, 4780, 4846, 5327, 5580 GO:0044255 BP e cellular lipid metabolic process 20/100 947/19669 5.062063690602843e-08 4 20 2.434536256199305e-06 335, 348, 350, 581, 847, 1559, 1571, 2052, 2180, 2194, 2876, 2944, 3030, 5130, 5465, 5468, 7276, 9370, 26061, 83667 GO:1903555 BP e regulation of tumor necrosis factor superfamily cytokine production 9/100 144/19669 5.0782447603400276e-08 7 9 2.43470987107891e-06 351, 3146, 3458, 3479, 3569, 5663, 9370, 9971, 729230 GO:0051172 BP e negative regulation of nitrogen compound metabolic process 32/100 2291/19669 5.1231771220024995e-08 5 32 2.44862409650989e-06 183, 196, 302, 348, 351, 581, 1719, 2023, 2876, 3146, 3440, 3458, 3479, 3553, 3569, 4137, 4318, 4851, 5071, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 9971, 83667 GO:0071902 BP e positive regulation of protein serine/threonine kinase activity 12/100 308/19669 5.3928883099455656e-08 11 12 2.5695526653270048e-06 183, 2081, 2180, 3458, 3479, 3553, 3654, 4217, 5663, 6622, 7422, 9370 GO:1901215 BP e negative regulation of neuron death 10/100 194/19669 5.539713579949106e-08 6 10 2.6313639504758256e-06 348, 581, 1440, 2896, 3162, 5071, 5465, 5663, 6347, 6622 GO:0002700 BP e regulation of production of molecular mediator of immune response 9/100 146/19669 5.722005197913181e-08 6 9 2.701277913984167e-06 335, 383, 3162, 3440, 3553, 3569, 5591, 9474, 729230 GO:0010634 BP e positive regulation of epithelial cell migration 9/100 146/19669 5.722005197913181e-08 8 9 2.701277913984167e-06 183, 2896, 3146, 3162, 3458, 4318, 4780, 4846, 7422 GO:0042594 BP e response to starvation 10/100 195/19669 5.814813854824027e-08 5 10 2.736696795894244e-06 213, 3309, 4217, 4780, 5166, 5465, 5468, 9474, 81631, 83667 GO:0033673 BP e negative regulation of kinase activity 11/100 251/19669 6.114254325414828e-08 9 11 2.863847380812079e-06 183, 348, 3458, 3553, 4137, 5071, 5580, 5663, 6622, 9104, 9370 GO:0033043 BP e regulation of organelle organization 22/100 1156/19669 6.122194855667147e-08 5 22 2.863847380812079e-06 302, 335, 581, 1440, 2023, 2876, 2896, 2934, 3064, 3479, 3553, 4137, 4318, 5071, 5580, 6622, 7422, 9474, 10096, 23476, 50507, 136319 GO:0048771 BP e tissue remodeling 7/100 70/19669 6.547668238606906e-08 2 7 3.053594369459403e-06 183, 383, 581, 4313, 4846, 9474, 729230 GO:0007166 BP e cell surface receptor signaling pathway 31/100 2190/19669 6.637643666419677e-08 5 31 3.0862035053232275e-06 60, 302, 335, 351, 581, 821, 1440, 2180, 3162, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4313, 4318, 4831, 4851, 5166, 5327, 5580, 5663, 6347, 6888, 7422, 9971, 10096, 729230 GO:1903037 BP e regulation of leukocyte cell-cell adhesion 12/100 317/19669 7.38498144573928e-08 6 12 3.4233392906604675e-06 383, 3146, 3440, 3458, 3479, 3553, 3569, 3654, 4860, 5465, 6347, 729230 GO:0002683 BP e negative regulation of immune system process 13/100 384/19669 7.498018262207136e-08 4 13 3.465300331993027e-06 335, 383, 2876, 2896, 3146, 3162, 3440, 4831, 5468, 5591, 6347, 9370, 729230 GO:0065007 BP e biological regulation 86/100 12086/19669 8.126269333027195e-08 1 86 3.7444097315954658e-06 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1401, 1440, 1559, 1719, 2023, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6696, 6888, 7276, 7422, 7450, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26762, 50507, 83667, 136319, 729230 GO:1901615 BP e organic hydroxy compound metabolic process 14/100 462/19669 8.949264931133972e-08 3 14 4.111319023586621e-06 335, 348, 351, 847, 1559, 1571, 1719, 3479, 5071, 6622, 6652, 7276, 9971, 136319 GO:0031324 BP e negative regulation of cellular metabolic process 33/100 2477/19669 9.095689374412713e-08 5 33 4.166150579530108e-06 183, 196, 302, 348, 351, 581, 1719, 2023, 2876, 3146, 3162, 3440, 3458, 3479, 3553, 3569, 4137, 4318, 4851, 5071, 5327, 5465, 5468, 5580, 5591, 5663, 6622, 7422, 9104, 9370, 9474, 9971, 83667 GO:0032411 BP e positive regulation of transporter activity 8/100 111/19669 9.64239614033863e-08 6 8 4.403456278926156e-06 3064, 3458, 5243, 5580, 6347, 9104, 9370, 729230 GO:0040008 BP e regulation of growth 16/100 625/19669 1.0101062012691489e-07 3 16 4.597618251165495e-06 183, 348, 351, 2023, 3458, 3479, 4137, 4851, 5071, 5465, 5468, 5591, 6696, 7422, 83667, 136319 GO:0009267 BP e cellular response to starvation 9/100 156/19669 1.0127307258902553e-07 6 9 4.597618251165495e-06 213, 3309, 4217, 4780, 5166, 5465, 9474, 81631, 83667 GO:0051091 BP e positive regulation of DNA-binding transcription factor activity 11/100 264/19669 1.0205288903195781e-07 11 11 4.619394006475973e-06 183, 351, 847, 1440, 3553, 3569, 3654, 5468, 7422, 11035, 136319 GO:0030195 BP e negative regulation of blood coagulation 6/100 45/19669 1.029602869045798e-07 8 6 4.6468000453415925e-06 348, 350, 2243, 4846, 5327, 5580 GO:0060341 BP e regulation of cellular localization 18/100 804/19669 1.1009853537437549e-07 4 18 4.943572185867168e-06 60, 302, 581, 2934, 3064, 3162, 3458, 3553, 3627, 4137, 5071, 5580, 5663, 6622, 9370, 9474, 9971, 83667 GO:0006873 BP e cellular ion homeostasis 16/100 629/19669 1.1017837945110065e-07 6 16 4.943572185867168e-06 348, 351, 581, 1152, 1244, 1356, 2896, 3064, 3146, 3162, 3627, 3934, 5663, 6622, 9104, 729230 GO:0019219 BP e regulation of nucleobase-containing compound metabolic process 43/100 3900/19669 1.110386470482195e-07 5 43 4.967688308349123e-06 183, 196, 348, 351, 581, 847, 1440, 1719, 2023, 2081, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0045597 BP e positive regulation of cell differentiation 18/100 805/19669 1.1215891486410796e-07 5 18 5.003262897851077e-06 183, 335, 1440, 2243, 3146, 3458, 3479, 3553, 3569, 4137, 4217, 4831, 4851, 4860, 5468, 5591, 7422, 9370 GO:1903530 BP e regulation of secretion by cell 15/100 550/19669 1.1732398289333105e-07 6 15 5.218543632162903e-06 183, 348, 2243, 3162, 3458, 3479, 3553, 3569, 4851, 5071, 6622, 6696, 9370, 9971, 729230 GO:1900047 BP e negative regulation of hemostasis 6/100 46/19669 1.1791996461372132e-07 5 6 5.229937335461587e-06 348, 350, 2243, 4846, 5327, 5580 GO:0036003 BP e positive regulation of transcription from RNA polymerase II promoter in response to stress 5/100 24/19669 1.2088642261368692e-07 12 5 5.3460978276570166e-06 3309, 4780, 4851, 7422, 83667 GO:0002709 BP e regulation of T cell mediated immunity 7/100 77/19669 1.2759702016756524e-07 7 7 5.626699542632748e-06 383, 3146, 3440, 3553, 3569, 11035, 729230 GO:0001959 BP e regulation of cytokine-mediated signaling pathway 9/100 161/19669 1.3272940443696268e-07 6 9 5.836301526528159e-06 335, 383, 3458, 3569, 3654, 5071, 5468, 9370, 9971 GO:0010906 BP e regulation of glucose metabolic process 8/100 116/19669 1.3588252918014126e-07 7 8 5.957926279436962e-06 3146, 3479, 5071, 5166, 5465, 9104, 9370, 83667 GO:1900542 BP e regulation of purine nucleotide metabolic process 8/100 117/19669 1.452494697063131e-07 8 8 6.350537894261813e-06 351, 2023, 3458, 3479, 4846, 5166, 5465, 5663 GO:0001933 BP e negative regulation of protein phosphorylation 12/100 338/19669 1.4804281564927697e-07 9 12 6.45433125451097e-06 183, 348, 581, 3458, 3553, 5071, 5580, 5591, 5663, 6622, 9104, 9370 GO:0050819 BP e negative regulation of coagulation 6/100 48/19669 1.5322620252839206e-07 5 6 6.661444228564842e-06 348, 350, 2243, 4846, 5327, 5580 GO:0051101 BP e regulation of DNA binding 8/100 118/19669 1.5516560827014817e-07 4 8 6.726756933176283e-06 3146, 3162, 3458, 3479, 4318, 5071, 5468, 5663 GO:0009889 BP e regulation of biosynthetic process 44/100 4083/19669 1.6011870132203854e-07 4 44 6.921985430747676e-06 183, 196, 335, 348, 351, 847, 1440, 1719, 2023, 2194, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0006140 BP e regulation of nucleotide metabolic process 8/100 119/19669 1.656574844683811e-07 7 8 7.136545779720726e-06 351, 2023, 3458, 3479, 4846, 5166, 5465, 5663 GO:1904035 BP e regulation of epithelial cell apoptotic process 7/100 80/19669 1.6647303020920993e-07 7 7 7.136545779720726e-06 2243, 2934, 3162, 3569, 4780, 5465, 6347 GO:0033273 BP e response to vitamin 7/100 80/19669 1.6647303020920993e-07 6 7 7.136545779720726e-06 383, 847, 2934, 3627, 4524, 5468, 6696 GO:0001818 BP e negative regulation of cytokine production 11/100 278/19669 1.7177794367804855e-07 7 11 7.343507092236575e-06 335, 383, 3146, 3162, 3440, 3458, 3479, 3569, 5465, 9370, 9971 GO:0042593 BP e glucose homeostasis 9/100 166/19669 1.723736273719765e-07 6 9 7.348559903752682e-06 2081, 3569, 4831, 5166, 5468, 5836, 9370, 9971, 83667 GO:0032944 BP e regulation of mononuclear cell proliferation 10/100 220/19669 1.7980567979324388e-07 6 10 7.644224895077413e-06 196, 383, 1401, 3146, 3479, 3553, 3569, 4860, 11035, 729230 GO:0033500 BP e carbohydrate homeostasis 9/100 167/19669 1.8143324517218096e-07 5 9 7.69216981597759e-06 2081, 3569, 4831, 5166, 5468, 5836, 9370, 9971, 83667 GO:0035821 BP e modulation of process of other organism 8/100 121/19669 1.8847966361840735e-07 2 8 7.968961601888157e-06 302, 348, 383, 1401, 3458, 5071, 5091, 9474 GO:0050673 BP e epithelial cell proliferation 7/100 82/19669 1.975848240766889e-07 3 7 8.308279897650932e-06 335, 581, 2081, 3146, 3162, 3569, 5663 GO:1903035 BP e negative regulation of response to wounding 7/100 82/19669 1.975848240766889e-07 6 7 8.308279897650932e-06 348, 350, 2243, 4846, 5327, 5580, 6696 GO:0061041 BP e regulation of wound healing 8/100 122/19669 2.0086818328422643e-07 6 8 8.423327903935269e-06 348, 350, 2243, 3146, 4780, 4846, 5327, 5580 GO:1990000 BP e amyloid fibril formation 4/100 11/19669 2.019569027534623e-07 5 4 8.445969384173327e-06 351, 2934, 4137, 11035 GO:0045936 BP e negative regulation of phosphate metabolic process 14/100 494/19669 2.0278749012058227e-07 7 14 8.457722148931601e-06 183, 348, 581, 3458, 3553, 4137, 5071, 5465, 5580, 5591, 5663, 6622, 9104, 9370 GO:0010563 BP e negative regulation of phosphorus metabolic process 14/100 495/19669 2.0782657475373093e-07 6 14 8.644462122864647e-06 183, 348, 581, 3458, 3553, 4137, 5071, 5465, 5580, 5591, 5663, 6622, 9104, 9370 GO:0031349 BP e positive regulation of defense response 12/100 349/19669 2.0898431413187177e-07 6 12 8.669187586225085e-06 183, 351, 383, 2896, 3146, 3458, 3553, 3569, 5580, 5591, 6622, 729230 GO:0050729 BP e positive regulation of inflammatory response 8/100 123/19669 2.1394892972321326e-07 7 8 8.851274270000676e-06 183, 351, 2896, 3458, 3553, 3569, 6622, 729230 GO:0032092 BP e positive regulation of protein binding 7/100 83/19669 2.1489190654643881e-07 5 7 8.866451586460303e-06 302, 348, 351, 1440, 4318, 5071, 5663 GO:0034248 BP e regulation of cellular amide metabolic process 13/100 421/19669 2.164874229089665e-07 5 13 8.908399568366295e-06 348, 351, 1719, 3458, 3479, 3569, 4780, 5166, 5580, 5591, 9971, 83667, 136319 GO:0090322 BP e regulation of superoxide metabolic process 5/100 27/19669 2.268477169565909e-07 6 5 9.294046921295463e-06 1401, 1719, 4137, 4780, 5580 GO:0002576 BP e platelet degranulation 8/100 124/19669 2.277537471224123e-07 8 8 9.294046921295463e-06 213, 335, 350, 351, 2243, 3479, 7422, 7450 GO:0010720 BP e positive regulation of cell development 11/100 286/19669 2.2827483666339738e-07 6 11 9.294046921295463e-06 335, 2243, 3458, 3553, 3569, 4137, 4851, 5468, 5591, 7422, 9370 GO:0043434 BP e response to peptide hormone 11/100 286/19669 2.2827483666339738e-07 6 11 9.294046921295463e-06 383, 847, 1244, 4780, 4831, 5465, 5468, 5580, 5591, 9370, 83667 GO:0060759 BP e regulation of response to cytokine stimulus 9/100 172/19669 2.3322445860063778e-07 4 9 9.470512975893972e-06 335, 383, 3458, 3569, 3654, 5071, 5468, 9370, 9971 GO:0051090 BP e regulation of DNA-binding transcription factor activity 13/100 426/19669 2.4775569824111285e-07 10 13 1.0034105778765071e-05 183, 351, 847, 1440, 3162, 3553, 3569, 3654, 5468, 7422, 9971, 11035, 136319 GO:0042116 BP e macrophage activation 6/100 52/19669 2.50070017180892e-07 5 6 1.0101253449905322e-05 351, 2896, 3146, 3458, 4137, 6622 GO:0010332 BP e response to gamma radiation 6/100 53/19669 2.8084063801585217e-07 5 6 1.1284954096772754e-05 581, 2876, 3309, 3627, 5591, 50507 GO:0046364 BP e monosaccharide biosynthetic process 6/100 53/19669 2.8084063801585217e-07 5 6 1.1284954096772754e-05 229, 2023, 5091, 6652, 6888, 9104 GO:0051249 BP e regulation of lymphocyte activation 13/100 431/19669 2.830175195404486e-07 6 13 1.1331631620934315e-05 196, 383, 3146, 3440, 3458, 3479, 3553, 3569, 4860, 5591, 6347, 11035, 729230 GO:0005996 BP e monosaccharide metabolic process 9/100 176/19669 2.834748651110924e-07 4 9 1.1331631620934315e-05 229, 1737, 2023, 5091, 5166, 6652, 6888, 9104, 9370 GO:0048732 BP e gland development 10/100 232/19669 2.9404070221606626e-07 4 10 1.1723539914780466e-05 335, 383, 2194, 3162, 3569, 4851, 5591, 5663, 9104, 11035 GO:0022408 BP e negative regulation of cell-cell adhesion 9/100 177/19669 2.9741662246959057e-07 6 9 1.1827498242395343e-05 335, 383, 3146, 3440, 4851, 5465, 5580, 7422, 9370 GO:0042178 BP e xenobiotic catabolic process 4/100 12/19669 3.0175327215912617e-07 4 4 1.196902798589936e-05 1244, 2180, 2944, 2947 GO:0008283 BP e cell population proliferation 13/100 434/19669 3.062741272762183e-07 2 13 1.2117117786069409e-05 335, 581, 2081, 2876, 3146, 3162, 3440, 3479, 3569, 4851, 5243, 5580, 5663 GO:0006959 BP e humoral immune response 10/100 234/19669 3.182707493146343e-07 3 10 1.2559453415262107e-05 1401, 2243, 3075, 3440, 3458, 3569, 3627, 3934, 4851, 6347 GO:1903531 BP e negative regulation of secretion by cell 8/100 130/19669 3.277195246488814e-07 7 8 1.289924164794446e-05 348, 3162, 3553, 4851, 5071, 6622, 9370, 729230 GO:0001774 BP e microglial cell activation 5/100 29/19669 3.31019192733888e-07 6 5 1.2995881061669736e-05 351, 2896, 3458, 4137, 6622 GO:0055080 BP e cation homeostasis 16/100 684/19669 3.4126800493266845e-07 6 16 1.3364159277134269e-05 348, 351, 581, 1356, 2896, 3064, 3146, 3162, 3627, 3934, 5071, 5166, 5663, 6622, 9104, 729230 GO:0003018 BP e vascular process in circulatory system 10/100 236/19669 3.442357508810943e-07 4 10 1.340803288872211e-05 183, 348, 1244, 1401, 2243, 2876, 4846, 5243, 7422, 9474 GO:0032502 BP e developmental process 49/100 4971/19669 3.452316957624583e-07 1 49 1.340803288872211e-05 60, 183, 196, 302, 335, 348, 351, 383, 581, 847, 1152, 1440, 1719, 2194, 2876, 2934, 2947, 3146, 3162, 3309, 3440, 3458, 3479, 3569, 3627, 3654, 4137, 4313, 4318, 4524, 4780, 4846, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6696, 7422, 9104, 9370, 9474, 9971, 11035, 50507, 136319 GO:0044403 BP e biological process involved in symbiotic interaction 18/100 869/19669 3.472956283498018e-07 2 18 1.340803288872211e-05 302, 348, 581, 821, 1401, 2876, 3075, 3146, 3654, 4217, 4780, 5071, 5091, 6347, 9474, 23476, 26762, 729230 GO:0043280 BP e positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 8/100 131/19669 3.475844734727975e-07 12 8 1.340803288872211e-05 581, 2934, 3146, 4137, 4217, 5468, 6622, 9131 GO:0001936 BP e regulation of endothelial cell proliferation 8/100 131/19669 3.475844734727975e-07 6 8 1.340803288872211e-05 348, 350, 383, 3146, 3162, 5468, 6347, 7422 GO:0006790 BP e sulfur compound metabolic process 12/100 366/19669 3.476156674853881e-07 3 12 1.340803288872211e-05 1244, 1737, 2180, 2194, 2876, 2941, 2944, 2947, 4143, 4524, 5091, 50507 GO:0048869 BP e cellular developmental process 33/100 2623/19669 3.527777374467363e-07 2 33 1.357312344826318e-05 60, 302, 351, 581, 847, 1440, 2194, 2876, 2934, 2947, 3146, 3309, 3440, 3458, 3479, 3569, 4137, 4313, 4318, 4851, 5465, 5468, 5580, 5591, 5663, 6696, 7422, 9370, 9474, 9971, 11035, 50507, 136319 GO:0070663 BP e regulation of leukocyte proliferation 10/100 237/19669 3.579015794656955e-07 5 10 1.3705262491429892e-05 196, 383, 1401, 3146, 3479, 3553, 3569, 4860, 11035, 729230 GO:0043254 BP e regulation of protein-containing complex assembly 13/100 440/19669 3.5799321127711614e-07 5 13 1.3705262491429892e-05 348, 581, 1440, 2934, 3146, 3309, 3458, 4137, 5580, 6622, 7422, 10096, 136319 GO:0070482 BP e response to oxygen levels 11/100 300/19669 3.675927107417162e-07 3 11 1.403784570301492e-05 847, 3162, 3654, 4313, 4524, 5465, 5468, 6649, 7422, 9370, 50507 GO:0009408 BP e response to heat 7/100 90/19669 3.7565303499545705e-07 4 7 1.427481532982737e-05 1244, 3162, 3479, 3627, 3654, 4137, 4846 GO:0019217 BP e regulation of fatty acid metabolic process 7/100 90/19669 3.7565303499545705e-07 6 7 1.427481532982737e-05 335, 3553, 5166, 5465, 5468, 9104, 9370 GO:0043388 BP e positive regulation of DNA binding 6/100 56/19669 3.923363394325863e-07 5 6 1.4872059763220447e-05 3146, 3458, 3479, 4318, 5071, 5468 GO:0045920 BP e negative regulation of exocytosis 5/100 30/19669 3.956266359316321e-07 8 5 1.4959935938545006e-05 3162, 4851, 5071, 6622, 729230 GO:0010745 BP e negative regulation of macrophage derived foam cell differentiation 4/100 13/19669 4.3416525646635366e-07 6 4 1.6376968865238187e-05 1401, 5465, 5468, 9370 GO:0032768 BP e regulation of monooxygenase activity 6/100 57/19669 4.367006655870875e-07 5 6 1.6397491236980732e-05 348, 1719, 3458, 3553, 4846, 6622 GO:0098869 BP e cellular oxidant detoxification 7/100 92/19669 4.368402473789539e-07 3 7 1.6397491236980732e-05 213, 348, 847, 2876, 4846, 6649, 83667 GO:0031400 BP e negative regulation of protein modification process 14/100 527/19669 4.424693388845299e-07 8 14 1.6568377434143345e-05 183, 348, 581, 3458, 3553, 4137, 5071, 5580, 5591, 5663, 6622, 9104, 9370, 9474 GO:0043405 BP e regulation of MAP kinase activity 11/100 306/19669 4.473871778963883e-07 11 11 1.6711865698605378e-05 183, 348, 2081, 3479, 3553, 3654, 4217, 5580, 5663, 7422, 9370 GO:0051252 BP e regulation of RNA metabolic process 40/100 3640/19669 4.620652319061614e-07 6 40 1.7218363000086743e-05 183, 196, 348, 351, 847, 1440, 1719, 2023, 2081, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0010743 BP e regulation of macrophage derived foam cell differentiation 5/100 31/19669 4.698130782921818e-07 5 5 1.7464790519122412e-05 183, 1401, 5465, 5468, 9370 GO:0006796 BP e phosphate-containing compound metabolic process 26/100 1766/19669 5.022738901112488e-07 4 26 1.8626494382679805e-05 229, 335, 351, 1152, 1737, 2023, 2081, 2180, 2194, 2876, 3030, 3654, 4199, 4217, 4831, 4860, 5130, 5166, 5580, 5591, 5836, 6347, 6652, 6888, 11035, 23476 GO:0014805 BP e smooth muscle adaptation 3/100 4/19669 5.081958438412738e-07 5 3 1.866619101841815e-05 3162, 3553, 4846 GO:1905908 BP e positive regulation of amyloid fibril formation 3/100 4/19669 5.081958438412738e-07 7 3 1.866619101841815e-05 348, 351, 5663 GO:0110112 BP e regulation of lipid transporter activity 3/100 4/19669 5.081958438412738e-07 8 3 1.866619101841815e-05 5468, 5580, 9370 GO:0002265 BP e astrocyte activation involved in immune response 3/100 4/19669 5.081958438412738e-07 4 3 1.866619101841815e-05 351, 2896, 5663 GO:1904064 BP e positive regulation of cation transmembrane transport 8/100 138/19669 5.177948992427497e-07 8 8 1.8973484522252184e-05 581, 3064, 3458, 3627, 6347, 6622, 9104, 729230 GO:0046686 BP e response to cadmium ion 6/100 59/19669 5.378066482665557e-07 5 6 1.9659962747796415e-05 383, 847, 2934, 3162, 4318, 6652 GO:0050731 BP e positive regulation of peptidyl-tyrosine phosphorylation 9/100 190/19669 5.40820251692004e-07 10 9 1.972327884725105e-05 183, 1440, 3440, 3458, 3479, 3569, 7422, 9370, 50507 GO:1901566 BP e organonitrogen compound biosynthetic process 18/100 896/19669 5.424261078061987e-07 4 18 1.973507753933191e-05 335, 348, 383, 1152, 1719, 1737, 2180, 2194, 2941, 2944, 2947, 3479, 3553, 4524, 4831, 4860, 5130, 6622 GO:0002573 BP e myeloid leukocyte differentiation 7/100 95/19669 5.442070068053766e-07 5 7 1.9753174138525345e-05 1440, 2194, 3458, 4318, 5468, 5663, 7422 GO:0010467 BP e gene expression 8/100 139/19669 5.471335149861336e-07 4 8 1.9812670107380226e-05 348, 3146, 3553, 3569, 4860, 9370, 9971, 50507 GO:1904707 BP e positive regulation of vascular associated smooth muscle cell proliferation 5/100 32/19669 5.545780557682344e-07 7 5 2.003510863444396e-05 2081, 3479, 4217, 4313, 4318 GO:0008150 BP e biological_process 100/100 16984/19669 5.899709155410403e-07 0 100 2.1263822927814074e-05 60, 183, 196, 213, 229, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1152, 1244, 1356, 1401, 1440, 1510, 1559, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 2941, 2944, 2947, 3030, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4143, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5130, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6649, 6652, 6696, 6888, 7276, 7422, 7450, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 50507, 81631, 83667, 136319, 729230 GO:1903961 BP e positive regulation of anion transmembrane transport 6/100 60/19669 5.951199917452989e-07 8 6 2.129975970455849e-05 2180, 3479, 4780, 5243, 5663, 9370 GO:0070542 BP e response to fatty acid 6/100 60/19669 5.951199917452989e-07 5 6 2.129975970455849e-05 847, 2180, 4831, 5166, 9370, 9971 GO:0001960 BP e negative regulation of cytokine-mediated signaling pathway 6/100 60/19669 5.951199917452989e-07 7 6 2.129975970455849e-05 335, 383, 3569, 5468, 9370, 9971 GO:0033135 BP e regulation of peptidyl-serine phosphorylation 8/100 141/19669 6.100972324456516e-07 9 8 2.1785142476423613e-05 351, 581, 1440, 3440, 3458, 3569, 6622, 7422 GO:0050866 BP e negative regulation of cell activation 9/100 193/19669 6.168290512681951e-07 5 9 2.197453495142945e-05 348, 383, 2896, 3146, 3162, 3440, 4846, 5580, 729230 GO:0034976 BP e response to endoplasmic reticulum stress 10/100 252/19669 6.282047011467851e-07 4 10 2.2328107045378804e-05 581, 821, 2081, 3309, 4217, 4780, 5071, 6347, 9131, 83667 GO:0090066 BP e regulation of anatomical structure size 12/100 388/19669 6.456443744050365e-07 3 12 2.2895085073948185e-05 183, 348, 1401, 1440, 2243, 2876, 2934, 4846, 5580, 9474, 10096, 136319 GO:0150077 BP e regulation of neuroinflammatory response 5/100 33/19669 6.509836568236139e-07 7 5 2.2978528620448205e-05 2896, 3479, 3553, 3569, 4318 GO:0002724 BP e regulation of T cell cytokine production 5/100 33/19669 6.509836568236139e-07 8 5 2.2978528620448205e-05 383, 3440, 3553, 3569, 729230 GO:2001141 BP e regulation of RNA biosynthetic process 38/100 3369/19669 6.580920489659261e-07 7 38 2.317628520271305e-05 183, 196, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0032147 BP e activation of protein kinase activity 11/100 319/19669 6.747085781453672e-07 11 11 2.36714951061819e-05 183, 2081, 3146, 3479, 3553, 3654, 4217, 5580, 5663, 7422, 11035 GO:0003008 BP e system process 23/100 1441/19669 6.752297824310496e-07 2 23 2.36714951061819e-05 183, 348, 351, 1244, 1401, 2243, 2876, 2934, 3064, 3162, 3479, 3553, 3627, 4137, 4846, 5071, 5243, 5663, 6347, 7422, 9474, 50507, 729230 GO:0006793 BP e phosphorus metabolic process 26/100 1794/19669 6.793740884450518e-07 3 26 2.376265277538488e-05 229, 335, 351, 1152, 1737, 2023, 2081, 2180, 2194, 2876, 3030, 3654, 4199, 4217, 4831, 4860, 5130, 5166, 5580, 5591, 5836, 6347, 6652, 6888, 11035, 23476 GO:0001974 BP e blood vessel remodeling 5/100 34/19669 7.6015583363984e-07 3 5 2.6527887255594416e-05 183, 581, 4846, 9474, 729230 GO:0050863 BP e regulation of T cell activation 11/100 323/19669 7.62671262160347e-07 7 11 2.6555454128162303e-05 383, 3146, 3440, 3458, 3479, 3553, 3569, 4860, 6347, 11035, 729230 GO:0032652 BP e regulation of interleukin-1 production 7/100 100/19669 7.722128954644717e-07 7 7 2.6826989754397784e-05 335, 351, 3146, 3458, 3479, 3569, 9971 GO:0051235 BP e maintenance of location 8/100 146/19669 7.952257969590357e-07 3 8 2.756424552972874e-05 213, 335, 348, 2934, 3309, 3553, 3934, 5663 GO:0071363 BP e cellular response to growth factor stimulus 10/100 259/19669 8.063762105280065e-07 5 10 2.7887932314665213e-05 351, 383, 847, 2081, 3309, 4137, 4851, 6347, 7422, 50507 GO:2001237 BP e negative regulation of extrinsic apoptotic signaling pathway 7/100 101/19669 8.262916922792816e-07 9 7 2.851262139950256e-05 2243, 2876, 3064, 3162, 3479, 3553, 4846 GO:0009617 BP e response to bacterium 11/100 326/19669 8.351332676647063e-07 5 11 2.875324606120767e-05 1401, 1571, 2243, 2876, 3569, 3934, 5580, 5836, 6347, 9370, 9971 GO:2001056 BP e positive regulation of cysteine-type endopeptidase activity 8/100 147/19669 8.375007882551607e-07 11 8 2.87703953822476e-05 581, 2934, 3146, 4137, 4217, 5468, 6622, 9131 GO:0001558 BP e regulation of cell growth 12/100 398/19669 8.440845898987892e-07 5 12 2.8931986277377207e-05 183, 348, 2023, 3479, 4137, 5071, 5465, 5468, 6696, 7422, 83667, 136319 GO:0002685 BP e regulation of leukocyte migration 9/100 201/19669 8.664188928877199e-07 7 9 2.9631526136760026e-05 351, 3146, 3162, 3569, 3627, 6347, 7422, 11035, 729230 GO:0060761 BP e negative regulation of response to cytokine stimulus 6/100 64/19669 8.767532207219512e-07 5 6 2.9918474649469685e-05 335, 383, 3569, 5468, 9370, 9971 GO:0019538 BP e protein metabolic process 41/100 3875/19669 8.913034692829736e-07 4 41 3.034769998288709e-05 60, 213, 302, 335, 348, 350, 351, 847, 1356, 1510, 1737, 2081, 2243, 2876, 2934, 3309, 3479, 3569, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 5071, 5166, 5327, 5465, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 7450, 9474, 9971, 11035, 23476 GO:0001666 BP e response to hypoxia 10/100 262/19669 8.953511048351184e-07 5 10 3.0351219170512053e-05 847, 3162, 3654, 4313, 4524, 5465, 6649, 7422, 9370, 50507 GO:0022898 BP e regulation of transmembrane transporter activity 10/100 262/19669 8.953511048351184e-07 6 10 3.0351219170512053e-05 60, 351, 3064, 3458, 4318, 5243, 6347, 6622, 9104, 729230 GO:1904062 BP e regulation of cation transmembrane transport 11/100 331/19669 9.694579580871025e-07 7 11 3.279111642848462e-05 351, 581, 3064, 3458, 3627, 4318, 6347, 6622, 9104, 9474, 729230 GO:1902532 BP e negative regulation of intracellular signal transduction 13/100 481/19669 9.760210775536385e-07 7 13 3.2869131196493326e-05 183, 348, 2023, 2876, 3553, 4318, 4780, 5071, 5465, 5580, 9370, 9971, 83667 GO:0051048 BP e negative regulation of secretion 8/100 150/19669 9.760359296164683e-07 6 8 3.2869131196493326e-05 348, 3162, 3553, 4851, 5071, 6622, 9370, 729230 GO:0044282 BP e small molecule catabolic process 12/100 404/19669 9.876079451518025e-07 3 12 3.318621457617083e-05 229, 348, 383, 2023, 3030, 4143, 4846, 4860, 6652, 9370, 26061, 83667 GO:0010595 BP e positive regulation of endothelial cell migration 7/100 104/19669 1.0079669354978516e-06 9 7 3.372938928590409e-05 183, 2896, 3146, 3162, 4780, 4846, 7422 GO:0051179 BP e localization 47/100 4822/19669 1.0081558850887512e-06 1 47 3.372938928590409e-05 60, 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1356, 2180, 2243, 2896, 2934, 3064, 3146, 3309, 3479, 3553, 3569, 3934, 4137, 4318, 4831, 4860, 5071, 5243, 5465, 5468, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 7846, 9131, 9370, 9971, 10096, 10383, 26061, 83667 GO:2001236 BP e regulation of extrinsic apoptotic signaling pathway 8/100 151/19669 1.0263583951202482e-06 8 8 3.426389522971935e-05 183, 2243, 2876, 3064, 3162, 3479, 3553, 4846 GO:0031326 BP e regulation of cellular biosynthetic process 42/100 4001/19669 1.0492316657432666e-06 5 42 3.495167821599323e-05 183, 196, 335, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4846, 4851, 5071, 5166, 5465, 5468, 5580, 5591, 5663, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0061045 BP e negative regulation of wound healing 6/100 66/19669 1.0538385152729047e-06 7 6 3.5029319114578844e-05 348, 350, 2243, 4846, 5327, 5580 GO:1903959 BP e regulation of anion transmembrane transport 7/100 107/19669 1.2220054099372902e-06 7 7 4.044443711598902e-05 2180, 3479, 3553, 4780, 5243, 5663, 9370 GO:0033138 BP e positive regulation of peptidyl-serine phosphorylation 7/100 107/19669 1.2220054099372902e-06 10 7 4.044443711598902e-05 351, 1440, 3440, 3458, 3569, 6622, 7422 GO:0022409 BP e positive regulation of cell-cell adhesion 10/100 272/19669 1.2569774575076877e-06 6 10 4.149549925660636e-05 2243, 3146, 3458, 3479, 3553, 3569, 3654, 4860, 6347, 729230 GO:0043502 BP e regulation of muscle adaptation 6/100 68/19669 1.259155175622818e-06 6 6 4.149549925660636e-05 183, 3479, 4846, 4851, 5465, 136319 GO:0070555 BP e response to interleukin-1 7/100 108/19669 1.3013036987527063e-06 5 7 4.279287163206016e-05 351, 1244, 3553, 3654, 4524, 6347, 6622 GO:0009266 BP e response to temperature stimulus 8/100 156/19669 1.31253427506473e-06 3 8 4.307015456982132e-05 1244, 3162, 3479, 3627, 3654, 4137, 4846, 5468 GO:2000146 BP e negative regulation of cell motility 10/100 274/19669 1.3429216583792206e-06 6 10 4.388017902856944e-05 348, 350, 3146, 3162, 4780, 4851, 5468, 6347, 9104, 9370 GO:0036293 BP e response to decreased oxygen levels 10/100 274/19669 1.3429216583792206e-06 4 10 4.388017902856944e-05 847, 3162, 3654, 4313, 4524, 5465, 6649, 7422, 9370, 50507 GO:0034641 BP e cellular nitrogen compound metabolic process 36/100 3139/19669 1.3481953633043452e-06 3 36 4.3959166612826e-05 229, 351, 383, 581, 1244, 1559, 1719, 1737, 2023, 2081, 2180, 2194, 2876, 2941, 2944, 2947, 3146, 3162, 4137, 4199, 4524, 4831, 4846, 4851, 4860, 5071, 5091, 5465, 5468, 5591, 5663, 6622, 7276, 9971, 83667, 136319 GO:0048870 BP e cell motility 18/100 958/19669 1.4194745863679277e-06 3 18 4.618544161564991e-05 60, 335, 581, 2876, 3146, 3569, 3627, 4318, 4846, 4851, 5327, 5580, 5663, 6347, 6652, 7422, 10096, 729230 GO:0071637 BP e regulation of monocyte chemotactic protein-1 production 4/100 17/19669 1.422777572973316e-06 8 4 4.619524651489311e-05 3146, 3553, 9370, 9971 GO:0045785 BP e positive regulation of cell adhesion 12/100 420/19669 1.4816942841058547e-06 5 12 4.8006894805029694e-05 335, 2243, 3146, 3458, 3479, 3553, 3569, 3654, 4860, 6347, 7422, 729230 GO:0002701 BP e negative regulation of production of molecular mediator of immune response 5/100 39/19669 1.541549400931022e-06 7 5 4.984127159732863e-05 335, 383, 3162, 3440, 5591 GO:0001819 BP e positive regulation of cytokine production 12/100 423/19669 1.5955379338097443e-06 7 12 5.1478676732352126e-05 183, 351, 3146, 3162, 3458, 3553, 3569, 3654, 5591, 5663, 9370, 729230 GO:0006641 BP e triglyceride metabolic process 6/100 71/19669 1.6274811677906562e-06 7 6 5.239944596715104e-05 348, 350, 847, 1571, 2180, 2876 GO:0006355 BP e regulation of transcription, DNA-templated 37/100 3364/19669 1.6354845952122652e-06 9 37 5.254719816350055e-05 183, 196, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6622, 6696, 7422, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:1903506 BP e regulation of nucleic acid-templated transcription 37/100 3365/19669 1.6456232613193826e-06 8 37 5.276279581605271e-05 183, 196, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6622, 6696, 7422, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0006006 BP e glucose metabolic process 7/100 112/19669 1.662998730873112e-06 6 7 5.309865242352115e-05 229, 1737, 2023, 5091, 5166, 6652, 9370 GO:0072593 BP e reactive oxygen species metabolic process 7/100 112/19669 1.662998730873112e-06 3 7 5.309865242352115e-05 847, 2876, 4846, 5166, 6649, 50507, 83667 GO:0051271 BP e negative regulation of cellular component movement 10/100 281/19669 1.6854668661210883e-06 5 10 5.370462747329928e-05 348, 350, 3146, 3162, 4780, 4851, 5468, 6347, 9104, 9370 GO:0050670 BP e regulation of lymphocyte proliferation 9/100 218/19669 1.7001355734942164e-06 7 9 5.406009602495039e-05 196, 383, 3146, 3479, 3553, 3569, 4860, 11035, 729230 GO:0046688 BP e response to copper ion 5/100 40/19669 1.7546957219796226e-06 5 5 5.567993229127091e-05 351, 4780, 6622, 6649, 6652 GO:1903578 BP e regulation of ATP metabolic process 7/100 114/19669 1.8732356577051164e-06 4 7 5.9319129160662016e-05 351, 2023, 3458, 3479, 5465, 5663, 6622 GO:0006928 BP e movement of cell or subcellular component 22/100 1414/19669 1.9018225573688567e-06 2 22 6.010071695668729e-05 60, 335, 351, 581, 2876, 2934, 3064, 3146, 3569, 3627, 4137, 4318, 4846, 4851, 5327, 5580, 5663, 6347, 6652, 7422, 10096, 729230 GO:0031100 BP e animal organ regeneration 6/100 73/19669 1.918652917098964e-06 4 6 6.050833687326446e-05 335, 3162, 3569, 4851, 5468, 9104 GO:0042129 BP e regulation of T cell proliferation 8/100 165/19669 2.0003579552056253e-06 8 8 6.295605098285188e-05 383, 3146, 3479, 3553, 3569, 4860, 11035, 729230 GO:0055065 BP e metal ion homeostasis 14/100 600/19669 2.052580236568893e-06 7 14 6.446777518529648e-05 348, 351, 581, 1356, 3064, 3146, 3162, 3627, 3934, 5071, 5663, 6622, 9104, 729230 GO:0051234 BP e establishment of localization 43/100 4286/19669 2.1521686876989656e-06 2 43 6.745799613785555e-05 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1356, 2180, 2243, 2896, 2934, 3064, 3146, 3309, 3479, 3569, 3934, 4137, 4318, 4831, 4860, 5071, 5243, 5468, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 7846, 9131, 9971, 10096, 10383, 26061, 83667 GO:1901653 BP e cellular response to peptide 9/100 225/19669 2.206054763995879e-06 6 9 6.900646914206622e-05 351, 383, 3479, 4780, 5468, 5580, 5591, 5663, 9370 GO:0010042 BP e response to manganese ion 4/100 19/19669 2.29906152110372e-06 5 4 7.17698921090999e-05 351, 383, 3309, 5071 GO:0001676 BP e long-chain fatty acid metabolic process 7/100 118/19669 2.3608287439576187e-06 8 7 7.35488954848335e-05 1559, 1571, 2052, 2180, 2876, 2944, 26061 GO:0070848 BP e response to growth factor 10/100 292/19669 2.37791832624562e-06 4 10 7.393164250690928e-05 351, 383, 847, 2081, 3309, 4137, 4851, 6347, 7422, 50507 GO:0043603 BP e cellular amide metabolic process 14/100 609/19669 2.441013720631548e-06 4 14 7.574032492040226e-05 383, 1244, 1559, 1719, 1737, 2180, 2194, 2876, 2941, 2944, 2947, 4524, 5091, 5663 GO:0050794 BP e regulation of cellular process 78/100 10849/19669 2.456494435808425e-06 3 78 7.606730254948022e-05 60, 183, 196, 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 6888, 7276, 7422, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26762, 50507, 83667, 136319, 729230 GO:0035296 BP e regulation of tube diameter 7/100 119/19669 2.498026947621259e-06 5 7 7.704335616010255e-05 183, 348, 1401, 2243, 2876, 4846, 9474 GO:0097746 BP e blood vessel diameter maintenance 7/100 119/19669 2.498026947621259e-06 6 7 7.704335616010255e-05 183, 348, 1401, 2243, 2876, 4846, 9474 GO:1904783 BP e positive regulation of NMDA glutamate receptor activity 3/100 6/19669 2.522220230097134e-06 10 3 7.747898072094788e-05 3458, 6347, 729230 GO:0061419 BP e positive regulation of transcription from RNA polymerase II promoter in response to hypoxia 3/100 6/19669 2.522220230097134e-06 13 3 7.747898072094788e-05 4780, 4851, 7422 GO:0006469 BP e negative regulation of protein kinase activity 9/100 229/19669 2.5496804482379317e-06 10 9 7.816649820394774e-05 183, 348, 3458, 3553, 5580, 5663, 6622, 9104, 9370 GO:0035150 BP e regulation of tube size 7/100 120/19669 2.64182270095661e-06 4 7 8.083032081058096e-05 183, 348, 1401, 2243, 2876, 4846, 9474 GO:0044249 BP e cellular biosynthetic process 28/100 2187/19669 2.68879898366224e-06 3 28 8.210439753682911e-05 335, 348, 383, 581, 1559, 1571, 1719, 1737, 2180, 2194, 2876, 2941, 2944, 2947, 3479, 4143, 4199, 4524, 4831, 4846, 4851, 4860, 5130, 5465, 5468, 6622, 9104, 9971 GO:1903039 BP e positive regulation of leukocyte cell-cell adhesion 9/100 231/19669 2.7381314652788883e-06 7 9 8.344523415968731e-05 3146, 3458, 3479, 3553, 3569, 3654, 4860, 6347, 729230 GO:0048856 BP e anatomical structure development 36/100 3290/19669 2.7550835519388143e-06 2 36 8.379592068051057e-05 60, 183, 196, 302, 335, 351, 383, 581, 847, 1152, 1440, 1719, 2194, 2876, 2934, 2947, 3146, 3162, 3309, 3479, 3569, 3627, 4137, 4318, 4851, 5071, 5465, 5468, 5591, 5663, 6696, 7422, 9104, 9474, 11035, 136319 GO:0030003 BP e cellular cation homeostasis 14/100 616/19669 2.7872193021292027e-06 7 14 8.444838076732311e-05 348, 351, 581, 1356, 2896, 3064, 3146, 3162, 3627, 3934, 5663, 6622, 9104, 729230 GO:0010556 BP e regulation of macromolecule biosynthetic process 40/100 3847/19669 2.787509904470445e-06 5 40 8.444838076732311e-05 183, 196, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0010950 BP e positive regulation of endopeptidase activity 8/100 173/19669 2.848784466506558e-06 10 8 8.582867670265061e-05 581, 2934, 3146, 4137, 4217, 5468, 6622, 9131 GO:0090199 BP e regulation of release of cytochrome c from mitochondria 5/100 44/19669 2.849802065955456e-06 7 5 8.582867670265061e-05 581, 2876, 3479, 4318, 5071 GO:1904645 BP e response to amyloid-beta 5/100 44/19669 2.849802065955456e-06 6 5 8.582867670265061e-05 351, 3479, 4313, 4318, 5663 GO:2000479 BP e regulation of cAMP-dependent protein kinase activity 4/100 20/19669 2.862623987591079e-06 11 4 8.60464515020053e-05 3064, 3627, 9370, 83667 GO:0006810 BP e transport 42/100 4147/19669 2.9578066342159e-06 3 42 8.8734199026477e-05 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1356, 2180, 2243, 2896, 2934, 3064, 3146, 3309, 3479, 3569, 3934, 4137, 4318, 4831, 4860, 5071, 5243, 5468, 5580, 5663, 5836, 6622, 7276, 7422, 7450, 7846, 9131, 9971, 10383, 26061, 83667 GO:0006875 BP e cellular metal ion homeostasis 13/100 535/19669 3.160198845534763e-06 8 13 9.4621517962607e-05 348, 351, 581, 1356, 3064, 3146, 3162, 3627, 3934, 5663, 6622, 9104, 729230 GO:0048638 BP e regulation of developmental growth 10/100 302/19669 3.210325164384388e-06 4 10 9.593573646577811e-05 348, 351, 3479, 4137, 4851, 5071, 5465, 5591, 6696, 7422 GO:0010565 BP e regulation of cellular ketone metabolic process 8/100 176/19669 3.2374604757071347e-06 5 8 9.655914093242791e-05 335, 3553, 5166, 5465, 5468, 9104, 9370, 9971 GO:0002698 BP e negative regulation of immune effector process 7/100 124/19669 3.2880969135165707e-06 5 7 9.787971276406195e-05 335, 383, 2896, 3162, 3440, 5591, 729230 GO:0010888 BP e negative regulation of lipid storage 4/100 21/19669 3.522399333730897e-06 6 4 0.0001046519802048 1401, 3569, 5465, 5468 GO:0050789 BP e regulation of biological process 80/100 11388/19669 3.5637360402902097e-06 2 80 0.0001054018926793 60, 183, 196, 213, 302, 335, 348, 350, 351, 383, 581, 821, 847, 1244, 1401, 1440, 1719, 2023, 2081, 2180, 2194, 2243, 2876, 2896, 2934, 3064, 3075, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 3934, 4137, 4199, 4217, 4313, 4318, 4524, 4780, 4831, 4846, 4851, 4860, 5071, 5091, 5166, 5243, 5327, 5465, 5468, 5580, 5591, 5663, 6347, 6622, 6696, 6888, 7276, 7422, 7846, 9104, 9131, 9370, 9474, 9971, 10096, 10383, 11035, 23476, 26762, 50507, 83667, 136319, 729230 GO:0042304 BP e regulation of fatty acid biosynthetic process 5/100 46/19669 3.5681862304051865e-06 7 5 0.0001054018926793 335, 3553, 5166, 9104, 9370 GO:0031648 BP e protein destabilization 5/100 46/19669 3.5681862304051865e-06 4 5 0.0001054018926793 2934, 3064, 5071, 5591, 6622 GO:0040013 BP e negative regulation of locomotion 10/100 306/19669 3.608247067690369e-06 4 10 0.0001063810773405 348, 350, 3146, 3162, 4780, 4851, 5468, 6347, 9104, 9370 GO:0045087 BP e innate immune response 13/100 543/19669 3.715183454265897e-06 6 13 0.0001093244232526 351, 383, 1401, 2243, 3075, 3146, 3654, 3934, 4217, 5468, 5591, 9971, 10383 GO:1903131 BP e mononuclear cell differentiation 9/100 241/19669 3.871220597819339e-06 5 9 0.0001136224915314 2194, 3146, 3440, 3569, 5468, 5591, 5663, 7422, 11035 GO:0050878 BP e regulation of body fluid levels 11/100 382/19669 3.876010919687519e-06 3 11 0.0001136224915314 348, 350, 2243, 3440, 4780, 4846, 5327, 5580, 7422, 7450, 9474 GO:0044272 BP e sulfur compound biosynthetic process 8/100 181/19669 3.985296964295961e-06 4 8 0.0001166040309515 1737, 2180, 2194, 2941, 2944, 2947, 4143, 4524 GO:0032760 BP e positive regulation of tumor necrosis factor production 6/100 83/19669 4.083565237498684e-06 9 6 0.0001192525028559 351, 3146, 3458, 3569, 5663, 729230 GO:1901522 BP e positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 4/100 22/19669 4.288376302840397e-06 12 4 0.0001247601347839 4780, 4851, 7422, 83667 GO:0001935 BP e endothelial cell proliferation 4/100 22/19669 4.288376302840397e-06 4 4 0.0001247601347839 335, 2081, 3146, 3162 GO:0010469 BP e regulation of signaling receptor activity 8/100 183/19669 4.322968810747127e-06 6 8 0.0001255292264101 351, 3458, 5465, 5468, 5580, 5663, 6347, 729230 GO:0050679 BP e positive regulation of epithelial cell proliferation 8/100 184/19669 4.500703611902922e-06 6 8 0.0001304441216331 383, 2896, 3146, 3162, 3479, 4831, 4851, 7422 GO:0040011 BP e locomotion 18/100 1047/19669 4.9444394473762665e-06 1 18 0.0001430355697276 60, 335, 581, 2876, 3146, 3569, 3627, 4318, 4846, 4851, 5327, 5580, 5663, 6347, 6652, 7422, 10096, 729230 GO:1903557 BP e positive regulation of tumor necrosis factor superfamily cytokine production 6/100 86/19669 5.024506237138656e-06 8 6 0.000145079082532 351, 3146, 3458, 3569, 5663, 729230 GO:0071248 BP e cellular response to metal ion 8/100 187/19669 5.071541976031484e-06 5 8 0.0001461629794215 351, 2934, 3162, 3309, 4318, 4780, 5071, 6622 GO:0034391 BP e regulation of smooth muscle cell apoptotic process 4/100 23/19669 5.170963294972464e-06 8 4 0.00014874976656 350, 3458, 3479, 5468 GO:0043524 BP e negative regulation of neuron apoptotic process 7/100 133/19669 5.235327265703459e-06 8 7 0.0001503203108566 348, 581, 2896, 3162, 5071, 5663, 6347 GO:0032651 BP e regulation of interleukin-1 beta production 6/100 87/19669 5.374657132868584e-06 8 6 0.0001537471622209 335, 351, 3146, 3458, 3479, 3569 GO:0051702 BP e biological process involved in interaction with symbiont 6/100 87/19669 5.374657132868584e-06 3 6 0.0001537471622209 302, 348, 1401, 2876, 5071, 5091 GO:0097190 BP e apoptotic signaling pathway 9/100 254/19669 5.929649972276931e-06 5 9 0.0001693085585776 581, 2081, 3162, 3458, 4217, 5580, 5591, 9131, 11035 GO:0002696 BP e positive regulation of leukocyte activation 10/100 324/19669 5.976889033766681e-06 6 10 0.0001703413374623 3146, 3458, 3479, 3553, 3569, 4860, 5591, 6347, 26762, 729230 GO:0010676 BP e positive regulation of cellular carbohydrate metabolic process 5/100 51/19669 5.993082494490909e-06 7 5 0.0001704871341778 3146, 3479, 5465, 6622, 9104 GO:0030154 BP e cell differentiation 25/100 1888/19669 6.0096183576128965e-06 3 25 0.0001706421153573 581, 847, 1440, 2194, 2876, 3146, 3309, 3440, 3458, 3479, 3569, 4137, 4313, 4318, 4851, 5465, 5468, 5591, 5663, 6696, 7422, 9370, 9971, 11035, 136319 GO:0045944 BP e positive regulation of transcription by RNA polymerase II 19/100 1172/19669 6.054878913811781e-06 11 19 0.0001716106565074 351, 1440, 3146, 3309, 3479, 3569, 3627, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 7422, 9971, 10096, 23476, 83667 GO:0043470 BP e regulation of carbohydrate catabolic process 6/100 89/19669 6.134483999514618e-06 6 6 0.0001732288233991 351, 3146, 3458, 3479, 5465, 5663 GO:1901216 BP e positive regulation of neuron death 6/100 89/19669 6.134483999514618e-06 6 6 0.0001732288233991 581, 2896, 3458, 4137, 4217, 6622 GO:0045821 BP e positive regulation of glycolytic process 4/100 24/19669 6.180978669592418e-06 10 4 0.0001741817228229 351, 3458, 3479, 5663 GO:0016043 BP e cellular component organization 47/100 5128/19669 6.190864352447635e-06 3 47 0.0001741817228229 60, 183, 213, 229, 302, 335, 348, 351, 581, 847, 1440, 1719, 2243, 2896, 2934, 3064, 3146, 3569, 4137, 4143, 4313, 4318, 4524, 4846, 4851, 5071, 5243, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 7450, 7846, 9131, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 81631, 136319 GO:0051051 BP e negative regulation of transport 11/100 403/19669 6.4451703227102425e-06 5 11 0.0001810057869826 348, 3146, 3162, 3553, 4318, 4851, 5071, 6622, 9370, 9474, 729230 GO:0051651 BP e maintenance of location in cell 6/100 90/19669 6.545829068578956e-06 4 6 0.0001834978312667 213, 348, 2934, 3309, 3934, 5663 GO:0043536 BP e positive regulation of blood vessel endothelial cell migration 5/100 52/19669 6.604041268449777e-06 10 5 0.0001844577043946 3146, 3162, 4780, 4846, 7422 GO:0071320 BP e cellular response to cAMP 5/100 52/19669 6.604041268449777e-06 7 5 0.0001844577043946 196, 351, 3309, 9370, 50507 GO:0030336 BP e negative regulation of cell migration 9/100 259/19669 6.940244138485508e-06 7 9 0.0001931471198757 348, 350, 3146, 3162, 4780, 4851, 5468, 6347, 9370 GO:0046883 BP e regulation of hormone secretion 9/100 259/19669 6.940244138485508e-06 7 9 0.0001931471198757 183, 2243, 3458, 3553, 3569, 5071, 6696, 9370, 9971 GO:0010596 BP e negative regulation of endothelial cell migration 5/100 53/19669 7.2627080010154e-06 9 5 0.0002013929299741 348, 350, 3146, 4851, 5468 GO:0010611 BP e regulation of cardiac muscle hypertrophy 5/100 53/19669 7.2627080010154e-06 7 5 0.0002013929299741 183, 3479, 4851, 5465, 136319 GO:0034114 BP e regulation of heterotypic cell-cell adhesion 4/100 25/19669 7.3296411748791505e-06 6 4 0.000202883413096 335, 2243, 3553, 9370 GO:0050867 BP e positive regulation of cell activation 10/100 334/19669 7.801462776718792e-06 5 10 0.0002155556770802 3146, 3458, 3479, 3553, 3569, 4860, 5591, 6347, 26762, 729230 GO:0043170 BP e macromolecule metabolic process 51/100 5825/19669 7.869290042128866e-06 3 51 0.0002170400963232 60, 213, 302, 335, 348, 350, 351, 581, 847, 1356, 1510, 1737, 2081, 2243, 2876, 2934, 3146, 3309, 3479, 3553, 3569, 3654, 4137, 4217, 4313, 4318, 4780, 4831, 4851, 4860, 5071, 5166, 5327, 5465, 5468, 5580, 5591, 5663, 5836, 6347, 6622, 6696, 7276, 7450, 9370, 9474, 9971, 11035, 23476, 50507, 83667 GO:0071345 BP e cellular response to cytokine stimulus 11/100 413/19669 8.121413353229978e-06 5 11 0.0002235931153957 383, 1244, 1440, 2194, 2934, 3146, 3309, 4217, 4780, 6347, 10096 GO:0019637 BP e organophosphate metabolic process 16/100 876/19669 8.413832579884697e-06 4 16 0.0002312301489364 229, 335, 1152, 1737, 2023, 2180, 2194, 2876, 3030, 4199, 4831, 4860, 5130, 5836, 6652, 6888 GO:0097193 BP e intrinsic apoptotic signaling pathway 7/100 143/19669 8.439818941686945e-06 6 7 0.0002315308618762 581, 2081, 3162, 4217, 5580, 5591, 9131 GO:0002719 BP e negative regulation of cytokine production involved in immune response 4/100 26/19669 8.628560498885733e-06 8 4 0.0002362874485371 335, 383, 3162, 3440 GO:0050777 BP e negative regulation of immune response 7/100 144/19669 8.834460572517733e-06 5 7 0.0002414961779947 383, 2876, 2896, 3162, 3440, 5468, 729230 GO:0051817 BP e modulation of process of other organism involved in symbiotic interaction 6/100 96/19669 9.510205783454916e-06 3 6 0.0002595072110059 302, 348, 1401, 5071, 5091, 9474 GO:0014743 BP e regulation of muscle hypertrophy 5/100 56/19669 9.551468223420695e-06 6 5 0.0002601718512538 183, 3479, 4851, 5465, 136319 GO:0050996 BP e positive regulation of lipid catabolic process 4/100 27/19669 1.0089727939439524e-05 7 4 0.0002725888120012 335, 3553, 5465, 5580 GO:0045940 BP e positive regulation of steroid metabolic process 4/100 27/19669 1.0089727939439524e-05 7 4 0.0002725888120012 183, 335, 348, 3458 GO:0034620 BP e cellular response to unfolded protein 4/100 27/19669 1.0089727939439524e-05 6 4 0.0002725888120012 581, 2081, 3309, 5071 GO:0043500 BP e muscle adaptation 4/100 27/19669 1.0089727939439524e-05 4 4 0.0002725888120012 2934, 3162, 3553, 4846 GO:0042102 BP e positive regulation of T cell proliferation 6/100 97/19669 1.0095881925970564e-05 9 6 0.0002725888120012 3146, 3479, 3553, 3569, 4860, 729230 GO:0050778 BP e positive regulation of immune response 13/100 596/19669 1.0125811117710662e-05 5 13 0.0002729180965001 60, 581, 1401, 3075, 3146, 3458, 3553, 3569, 5580, 5591, 5663, 10096, 729230 GO:0071840 BP e cellular component organization or biogenesis 47/100 5175/19669 1.0157586109659512e-05 2 47 0.0002732958920063 60, 183, 213, 229, 302, 335, 348, 351, 581, 847, 1440, 1719, 2243, 2896, 2934, 3064, 3146, 3569, 4137, 4143, 4313, 4318, 4524, 4846, 4851, 5071, 5243, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 7450, 7846, 9131, 9474, 9971, 10096, 10383, 11035, 23476, 26061, 26762, 81631, 136319 GO:0010873 BP e positive regulation of cholesterol esterification 3/100 9/19669 1.0476293132130732e-05 8 3 0.0002813789726064 183, 335, 348 GO:0010817 BP e regulation of hormone levels 12/100 509/19669 1.0546465253183634e-05 3 12 0.0002827702094886 183, 1244, 1559, 2243, 3458, 3553, 3569, 5071, 6696, 7276, 9370, 9971 GO:0006638 BP e neutral lipid metabolic process 6/100 98/19669 1.07104225468345e-05 5 6 0.0002861691024232 348, 350, 847, 1571, 2180, 2876 GO:0006639 BP e acylglycerol metabolic process 6/100 98/19669 1.07104225468345e-05 6 6 0.0002861691024232 348, 350, 847, 1571, 2180, 2876 GO:0007162 BP e negative regulation of cell adhesion 9/100 274/19669 1.0904814163750018e-05 5 9 0.0002908580415599 335, 383, 3146, 3440, 4851, 5465, 5580, 7422, 9370 GO:0044089 BP e positive regulation of cellular component biogenesis 12/100 511/19669 1.0968283855359108e-05 5 12 0.0002920447898511 183, 335, 581, 1440, 2934, 3064, 3458, 4137, 6622, 7422, 10096, 50507 GO:0002703 BP e regulation of leukocyte mediated immunity 8/100 208/19669 1.105898185824162e-05 5 8 0.0002939511758175 383, 3146, 3162, 3440, 3553, 3569, 11035, 729230 GO:0120035 BP e regulation of plasma membrane bounded cell projection organization 13/100 602/19669 1.1263816496076171e-05 6 13 0.0002988795446114 348, 2896, 3064, 3309, 4137, 4780, 4831, 5580, 5663, 6696, 7422, 9474, 10096 GO:1904018 BP e positive regulation of vasculature development 7/100 150/19669 1.1537801565179654e-05 6 7 0.0003045742128441 2896, 3146, 3162, 3553, 4780, 4846, 7422 GO:0010821 BP e regulation of mitochondrion organization 7/100 150/19669 1.1537801565179654e-05 6 7 0.0003045742128441 581, 2876, 3064, 3479, 4137, 4318, 5071 GO:0045766 BP e positive regulation of angiogenesis 7/100 150/19669 1.1537801565179654e-05 7 7 0.0003045742128441 2896, 3146, 3162, 3553, 4780, 4846, 7422 GO:0009314 BP e response to radiation 11/100 429/19669 1.1597083622460106e-05 3 11 0.0003056149262836 351, 581, 847, 2876, 3309, 3627, 4313, 4318, 5580, 5591, 50507 GO:0050870 BP e positive regulation of T cell activation 8/100 210/19669 1.1855531786622642e-05 8 8 0.0003118916823865 3146, 3458, 3479, 3553, 3569, 4860, 6347, 729230 GO:0033559 BP e unsaturated fatty acid metabolic process 6/100 101/19669 1.2738009646785482e-05 8 6 0.0003345357823618 1559, 1571, 2052, 2180, 2876, 2944 GO:0019318 BP e hexose metabolic process 7/100 153/19669 1.3127073293293775e-05 5 7 0.0003435810509928 229, 1737, 2023, 5091, 5166, 6652, 9370 GO:0002822 BP e regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/100 153/19669 1.3127073293293775e-05 6 7 0.0003435810509928 383, 3146, 3440, 3553, 3569, 11035, 729230 GO:0016032 BP e viral process 14/100 706/19669 1.3181824891793889e-05 3 14 0.0003444283278178 302, 348, 581, 821, 3075, 3146, 3654, 4217, 4780, 5091, 6347, 9474, 23476, 729230 GO:0051851 BP e modulation by host of symbiont process 5/100 60/19669 1.3438793463423352e-05 4 5 0.0003499543678546 302, 348, 1401, 5071, 5091 GO:0032890 BP e regulation of organic acid transport 5/100 60/19669 1.3438793463423352e-05 7 5 0.0003499543678546 383, 2180, 3553, 5465, 5663 GO:0032414 BP e positive regulation of ion transmembrane transporter activity 6/100 102/19669 1.3478915703082834e-05 8 6 0.0003504062714027 3064, 3458, 5243, 6347, 9104, 729230 GO:0044788 BP e modulation by host of viral process 4/100 29/19669 1.3548625274604356e-05 5 4 0.0003510325639329 348, 1401, 5071, 5091 GO:0042311 BP e vasodilation 4/100 29/19669 1.3548625274604356e-05 7 4 0.0003510325639329 348, 2876, 4846, 9474 GO:0071241 BP e cellular response to inorganic substance 8/100 214/19669 1.3594438585802652e-05 4 8 0.0003516275795554 351, 2934, 3162, 3309, 4318, 4780, 5071, 6622 GO:2001242 BP e regulation of intrinsic apoptotic signaling pathway 7/100 154/19669 1.3695465990724411e-05 8 7 0.0003536074586872 581, 2023, 2876, 4318, 4780, 5071, 11035 GO:0051251 BP e positive regulation of lymphocyte activation 9/100 282/19669 1.3716936506581137e-05 7 9 0.0003536074586872 3146, 3458, 3479, 3553, 3569, 4860, 5591, 6347, 729230 GO:0035690 BP e cellular response to drug 5/100 61/19669 1.4579994315371328e-05 4 5 0.0003752276128989 1244, 3309, 3553, 4780, 9370 GO:0031344 BP e regulation of cell projection organization 13/100 618/19669 1.4868312049273811e-05 5 13 0.0003799301296667 348, 2896, 3064, 3309, 4137, 4780, 4831, 5580, 5663, 6696, 7422, 9474, 10096 GO:0002706 BP e regulation of lymphocyte mediated immunity 7/100 156/19669 1.4893484733678196e-05 6 7 0.0003799301296667 383, 3146, 3440, 3553, 3569, 11035, 729230 GO:0051100 BP e negative regulation of binding 7/100 156/19669 1.4893484733678196e-05 4 7 0.0003799301296667 60, 581, 3162, 5465, 5580, 5663, 9370 GO:0060353 BP e regulation of cell adhesion molecule production 3/100 10/19669 1.4910838097381376e-05 4 3 0.0003799301296667 335, 3553, 4851 GO:1903624 BP e regulation of DNA catabolic process 3/100 10/19669 1.4910838097381376e-05 7 3 0.0003799301296667 581, 3569, 9104 GO:0031639 BP e plasminogen activation 3/100 10/19669 1.4910838097381376e-05 8 3 0.0003799301296667 350, 2243, 5327 GO:0048468 BP e cell development 13/100 619/19669 1.5124016291226092e-05 3 13 0.0003847249763999 302, 351, 581, 2194, 2876, 2934, 2947, 3479, 4137, 4851, 5663, 7422, 9474 GO:0002828 BP e regulation of type 2 immune response 4/100 30/19669 1.5572163527233268e-05 5 4 0.0003954712816569 383, 3440, 3569, 729230 GO:0043467 BP e regulation of generation of precursor metabolites and energy 7/100 158/19669 1.617693623330295e-05 5 7 0.0004101532926367 351, 3146, 3458, 3479, 5465, 5663, 6622 GO:0031647 BP e regulation of protein stability 9/100 289/19669 1.6663970383144623e-05 3 9 0.0004218067503233 335, 2896, 2934, 3064, 3479, 5071, 5580, 5591, 6622 GO:0051092 BP e positive regulation of NF-kappaB transcription factor activity 7/100 159/19669 1.6852161015864745e-05 12 7 0.0004258698818294 183, 351, 847, 3553, 3654, 11035, 136319 GO:2000401 BP e regulation of lymphocyte migration 5/100 63/19669 1.7088254059511255e-05 9 5 0.000431128245862 351, 3627, 6347, 11035, 729230 GO:0046395 BP e carboxylic acid catabolic process 8/100 222/19669 1.7722455669166195e-05 6 8 0.0004456676352099 383, 3030, 4143, 4846, 6652, 9370, 26061, 83667 GO:0097305 BP e response to alcohol 8/100 222/19669 1.7722455669166195e-05 4 8 0.0004456676352099 196, 847, 1440, 1571, 2934, 5465, 5468, 9370 GO:0032373 BP e positive regulation of sterol transport 4/100 31/19669 1.780954877946047e-05 9 4 0.0004463989506773 302, 335, 348, 9370 GO:0032376 BP e positive regulation of cholesterol transport 4/100 31/19669 1.780954877946047e-05 10 4 0.0004463989506773 302, 335, 348, 9370 GO:0006725 BP e cellular aromatic compound metabolic process 31/100 2807/19669 1.7898993470192275e-05 3 31 0.0004479113975711 229, 351, 581, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2876, 2944, 2947, 3146, 3162, 4137, 4199, 4524, 4831, 4851, 4860, 5071, 5465, 5468, 5591, 6622, 7276, 9971, 83667, 136319 GO:2000112 BP e regulation of cellular macromolecule biosynthetic process 38/100 3818/19669 1.812774028788688e-05 6 38 0.0004528992256989 183, 196, 348, 351, 847, 1440, 1719, 2023, 3146, 3162, 3309, 3440, 3458, 3479, 3553, 3569, 3627, 3654, 4217, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6622, 6696, 7422, 9104, 9370, 9971, 10096, 11035, 23476, 83667, 136319 GO:0050766 BP e positive regulation of phagocytosis 5/100 64/19669 1.846211006210465e-05 7 5 0.0004605054681617 335, 3458, 3553, 5468, 6347 GO:0043618 BP e regulation of transcription from RNA polymerase II promoter in response to stress 6/100 109/19669 1.969865329151969e-05 11 6 0.0004905538416771 3162, 3309, 4780, 4851, 7422, 83667 GO:0043542 BP e endothelial cell migration 5/100 65/19669 1.992045534864625e-05 7 5 0.0004952759415438 335, 2876, 3146, 4846, 7422 GO:0034369 BP e plasma lipoprotein particle remodeling 4/100 32/19669 2.027454459712683e-05 7 4 0.00050164829799 183, 213, 335, 348 GO:0034368 BP e protein-lipid complex remodeling 4/100 32/19669 2.027454459712683e-05 6 4 0.00050164829799 183, 213, 335, 348 GO:0032770 BP e positive regulation of monooxygenase activity 4/100 32/19669 2.027454459712683e-05 6 4 0.00050164829799 348, 1719, 3458, 3553 GO:0071639 BP e positive regulation of monocyte chemotactic protein-1 production 3/100 11/19669 2.0426668546448772e-05 9 3 0.0005021827938176 3146, 3553, 9370 GO:0033197 BP e response to vitamin E 3/100 11/19669 2.0426668546448772e-05 7 3 0.0005021827938176 383, 847, 5468 GO:2000551 BP e regulation of T-helper 2 cell cytokine production 3/100 11/19669 2.0426668546448772e-05 9 3 0.0005021827938176 383, 3440, 3569 GO:0043619 BP e regulation of transcription from RNA polymerase II promoter in response to oxidative stress 3/100 11/19669 2.0426668546448772e-05 12 3 0.0005021827938176 3162, 4780, 83667 GO:0007568 BP e aging 8/100 228/19669 2.146937015590686e-05 2 8 0.0005269754492813 383, 847, 2934, 3654, 4780, 5580, 9104, 50507 GO:0005975 BP e carbohydrate metabolic process 11/100 459/19669 2.1700304234596827e-05 3 11 0.0005317956722459 229, 1737, 2023, 4199, 5091, 5166, 5836, 6652, 6888, 9104, 9370 GO:0071675 BP e regulation of mononuclear cell migration 6/100 111/19669 2.1846404067238877e-05 8 6 0.0005345248944273 351, 3146, 3627, 6347, 11035, 729230 GO:0043406 BP e positive regulation of MAP kinase activity 8/100 230/19669 2.285737324429756e-05 12 8 0.0005583729749678 183, 2081, 3479, 3553, 3654, 4217, 5663, 7422 GO:0007566 BP e embryo implantation 4/100 33/19669 2.2981242658073986e-05 2 4 0.0005587382693645 3553, 4313, 4318, 6696 GO:0070059 BP e intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 4/100 33/19669 2.2981242658073986e-05 7 4 0.0005587382693645 581, 2081, 4217, 9131 GO:0010656 BP e negative regulation of muscle cell apoptotic process 4/100 33/19669 2.2981242658073986e-05 8 4 0.0005587382693645 350, 3162, 3479, 4780 GO:0044057 BP e regulation of system process 12/100 551/19669 2.314360785093745e-05 4 12 0.0005617983041418 183, 335, 348, 351, 2023, 2243, 3479, 4846, 4851, 5465, 9370, 136319 GO:0072507 BP e divalent inorganic cation homeostasis 11/100 464/19669 2.3972354112326173e-05 7 11 0.0005809992595097 348, 351, 581, 3064, 3146, 3627, 5071, 5663, 6622, 9104, 729230 GO:0002819 BP e regulation of adaptive immune response 7/100 168/19669 2.4046514409020612e-05 5 7 0.0005818802779163 383, 3146, 3440, 3553, 3569, 11035, 729230 GO:0006090 BP e pyruvate metabolic process 5/100 68/19669 2.483894406070681e-05 7 5 0.0005999276875847 229, 1737, 2023, 4199, 5091 GO:0042176 BP e regulation of protein catabolic process 10/100 382/19669 2.487029660033012e-05 6 10 0.0005999276875847 302, 348, 2876, 3458, 3553, 4780, 5071, 5663, 6622, 9104 GO:0030099 BP e myeloid cell differentiation 7/100 169/19669 2.498217047166824e-05 4 7 0.0006007431305608 1440, 2194, 3458, 4318, 5468, 5663, 7422 GO:0010721 BP e negative regulation of cell development 7/100 169/19669 2.498217047166824e-05 6 7 0.0006007431305608 3479, 3553, 3569, 4851, 5663, 6696, 7422 GO:0016477 BP e cell migration 15/100 851/19669 2.517742767402728e-05 4 15 0.0006044939343264 335, 581, 2876, 3146, 3569, 3627, 4318, 4846, 4851, 5327, 5580, 5663, 6347, 7422, 729230 GO:0019218 BP e regulation of steroid metabolic process 6/100 114/19669 2.5418162624055443e-05 6 6 0.0006077938881997 183, 335, 348, 2194, 3458, 9971 GO:0051621 BP e regulation of norepinephrine uptake 2/100 2/19669 2.559132160840943e-05 7 2 0.0006077938881997 60, 6622 GO:0110113 BP e positive regulation of lipid transporter activity 2/100 2/19669 2.559132160840943e-05 9 2 0.0006077938881997 5580, 9370 GO:0051563 BP e smooth endoplasmic reticulum calcium ion homeostasis 2/100 2/19669 2.559132160840943e-05 11 2 0.0006077938881997 351, 5663 GO:0003169 BP e coronary vein morphogenesis 2/100 2/19669 2.559132160840943e-05 6 2 0.0006077938881997 4851, 7422 GO:0014806 BP e smooth muscle hyperplasia 2/100 2/19669 2.559132160840943e-05 6 2 0.0006077938881997 3162, 4846 GO:0014900 BP e muscle hyperplasia 2/100 2/19669 2.559132160840943e-05 5 2 0.0006077938881997 3162, 4846 GO:0071870 BP e cellular response to catecholamine stimulus 4/100 34/19669 2.5944054234174085e-05 7 4 0.0006123910961103 351, 5071, 6622, 9370 GO:0071868 BP e cellular response to monoamine stimulus 4/100 34/19669 2.5944054234174085e-05 6 4 0.0006123910961103 351, 5071, 6622, 9370 GO:0034367 BP e protein-containing complex remodeling 4/100 34/19669 2.5944054234174085e-05 5 4 0.0006123910961103 183, 213, 335, 348 GO:0035967 BP e cellular response to topologically incorrect protein 4/100 34/19669 2.5944054234174085e-05 5 4 0.0006123910961103 581, 2081, 3309, 5071 GO:0014823 BP e response to activity 5/100 69/19669 2.6672186633539598e-05 2 5 0.0006275356755267 183, 847, 3569, 5591, 9370 GO:1904427 BP e positive regulation of calcium ion transmembrane transport 5/100 69/19669 2.6672186633539598e-05 9 5 0.0006275356755267 581, 3064, 3627, 6622, 9104 GO:0043620 BP e regulation of DNA-templated transcription in response to stress 6/100 115/19669 2.6707983591296027e-05 10 6 0.0006275356755267 3162, 3309, 4780, 4851, 7422, 83667 GO:0010872 BP e regulation of cholesterol esterification 3/100 12/19669 2.713497363850245e-05 7 3 0.0006356274646827 183, 335, 348 GO:0071287 BP e cellular response to manganese ion 3/100 12/19669 2.713497363850245e-05 6 3 0.0006356274646827 351, 3309, 5071 GO:1901575 BP e organic substance catabolic process 22/100 1672/19669 2.7453898375109604e-05 3 22 0.0006421208145789 229, 302, 348, 383, 2023, 2081, 2876, 3030, 3146, 3162, 3309, 4143, 4780, 4846, 4860, 5071, 5836, 6652, 6696, 9370, 26061, 83667 GO:0031334 BP e positive regulation of protein-containing complex assembly 8/100 237/19669 2.8323606340236957e-05 6 8 0.0006604550023882 581, 1440, 2934, 3458, 4137, 6622, 7422, 10096 GO:0016054 BP e organic acid catabolic process 8/100 237/19669 2.8323606340236957e-05 4 8 0.0006604550023882 383, 3030, 4143, 4846, 6652, 9370, 26061, 83667 GO:0032880 BP e regulation of protein localization 15/100 860/19669 2.8435216074576357e-05 4 15 0.0006620544257 60, 348, 2243, 2934, 3458, 3479, 3553, 3569, 4137, 5071, 5580, 5663, 9370, 9971, 83667 GO:0070201 BP e regulation of establishment of protein localization 12/100 563/19669 2.85790389708531e-05 5 12 0.0006640868962253 348, 2243, 3458, 3479, 3553, 3569, 4137, 5071, 5580, 5663, 9370, 9971 GO:0010633 BP e negative regulation of epithelial cell migration 5/100 70/19669 2.86088117087314e-05 8 5 0.0006640868962253 348, 350, 3146, 4851, 5468 GO:0043537 BP e negative regulation of blood vessel endothelial cell migration 4/100 35/19669 2.9177701791531337e-05 10 4 0.0006762723351982 348, 3146, 4851, 5468 GO:0002688 BP e regulation of leukocyte chemotaxis 6/100 117/19669 2.9445624367430445e-05 8 6 0.0006804326711933 3146, 3569, 3627, 6347, 7422, 729230 GO:0051928 BP e positive regulation of calcium ion transport 6/100 117/19669 2.9445624367430445e-05 8 6 0.0006804326711933 581, 3064, 3627, 6347, 6622, 9104 GO:0001894 BP e tissue homeostasis 7/100 174/19669 3.012254112672435e-05 5 7 0.0006950313462373 60, 213, 581, 3569, 4846, 4851, 7422 GO:0043627 BP e response to estrogen 5/100 71/19669 3.065285190461982e-05 5 5 0.0007062086688803 335, 1244, 2947, 3162, 5468 GO:0045471 BP e response to ethanol 6/100 119/19669 3.240448415967918e-05 5 6 0.0007454484472607 847, 1440, 1571, 2934, 5465, 9370 GO:2000310 BP e regulation of NMDA receptor activity 4/100 36/19669 3.269721069258083e-05 9 4 0.0007488245127363 351, 3458, 6347, 729230 GO:0055090 BP e acylglycerol homeostasis 4/100 36/19669 3.269721069258083e-05 6 4 0.0007488245127363 335, 348, 9971, 83667 GO:0070328 BP e triglyceride homeostasis 4/100 36/19669 3.269721069258083e-05 7 4 0.0007488245127363 335, 348, 9971, 83667 GO:0010508 BP e positive regulation of autophagy 6/100 120/19669 3.3970940025782626e-05 7 6 0.0007768391783013 3064, 3146, 3162, 3458, 5071, 83667 GO:0002829 BP e negative regulation of type 2 immune response 3/100 13/19669 3.514521615417295e-05 6 3 0.0008013109283151 383, 3440, 729230 GO:0036499 BP e PERK-mediated unfolded protein response 3/100 13/19669 3.514521615417295e-05 6 3 0.0008013109283151 3309, 4780, 6347 GO:0006066 BP e alcohol metabolic process 9/100 318/19669 3.53194769790775e-05 4 9 0.0008040928264911 335, 348, 351, 847, 1559, 1719, 3479, 6652, 7276 GO:0016051 BP e carbohydrate biosynthetic process 6/100 122/19669 3.728630300333183e-05 4 6 0.0008476162529117 229, 2023, 5091, 6652, 6888, 9104 GO:0051279 BP e regulation of release of sequestered calcium ion into cytosol 5/100 74/19669 3.747105841210492e-05 9 5 0.000850559865726 581, 3064, 3627, 6622, 9474 GO:0043407 BP e negative regulation of MAP kinase activity 5/100 75/19669 3.998677684750205e-05 12 5 0.0009063276814183 183, 348, 3553, 5580, 9370 GO:0010907 BP e positive regulation of glucose metabolic process 4/100 38/19669 4.065537949033932e-05 8 4 0.0009160853445919 3146, 3479, 5465, 9104 GO:0071869 BP e response to catecholamine 4/100 38/19669 4.065537949033932e-05 6 4 0.0009160853445919 351, 5071, 6622, 9370 GO:0071867 BP e response to monoamine 4/100 38/19669 4.065537949033932e-05 5 4 0.0009160853445919 351, 5071, 6622, 9370 GO:0043491 BP e protein kinase B signaling 4/100 38/19669 4.065537949033932e-05 6 4 0.0009160853445919 3479, 3553, 6347, 83667 GO:0032412 BP e regulation of ion transmembrane transporter activity 8/100 251/19669 4.257972146228889e-05 7 8 0.0009580437329015 351, 3064, 3458, 4318, 5243, 6347, 9104, 729230 GO:0010506 BP e regulation of autophagy 9/100 326/19669 4.2841107569687694e-05 6 9 0.0009625177306532 2081, 3064, 3146, 3162, 3458, 4137, 5071, 6622, 83667 GO:0060249 BP e anatomical structure homeostasis 9/100 327/19669 4.3870176307831465e-05 4 9 0.0009842011856815 60, 213, 581, 3569, 4846, 4851, 5071, 5591, 7422 GO:0035556 BP e intracellular signal transduction 20/100 1473/19669 4.412331261362592e-05 5 20 0.0009884392738336 183, 196, 348, 581, 2081, 2934, 3162, 3479, 3553, 3654, 4217, 4846, 5580, 5591, 5663, 6347, 9131, 11035, 83667, 729230 GO:1905906 BP e regulation of amyloid fibril formation 3/100 14/19669 4.456514961346463e-05 6 3 0.0009939965979003 348, 351, 5663 GO:0001921 BP e positive regulation of receptor recycling 3/100 14/19669 4.456514961346463e-05 6 3 0.0009939965979003 302, 5663, 6622 GO:2001138 BP e regulation of phospholipid transport 3/100 14/19669 4.456514961346463e-05 8 3 0.0009939965979003 335, 348, 5580 GO:0034381 BP e plasma lipoprotein particle clearance 4/100 39/19669 4.512553150323248e-05 2 4 0.0010021384268899 335, 348, 3162, 9370 GO:1902042 BP e negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/100 39/19669 4.512553150323248e-05 10 4 0.0010021384268899 2243, 2876, 3162, 4846 GO:1900371 BP e regulation of purine nucleotide biosynthetic process 4/100 39/19669 4.512553150323248e-05 9 4 0.0010021384268899 2023, 4846, 5166, 5465 GO:0032677 BP e regulation of interleukin-8 production 5/100 77/19669 4.540929133721454e-05 7 5 0.0010055381204024 1401, 3146, 3553, 3569, 9370 GO:0048145 BP e regulation of fibroblast proliferation 5/100 77/19669 4.540929133721454e-05 5 5 0.0010055381204024 183, 581, 3479, 5468, 5591 GO:0045861 BP e negative regulation of proteolysis 9/100 329/19669 4.599118704751666e-05 8 9 0.0010169602998006 183, 302, 351, 2876, 4318, 5327, 5663, 6622, 7422 GO:0008202 BP e steroid metabolic process 8/100 255/19669 4.760919076555255e-05 4 8 0.0010512273255119 335, 348, 351, 847, 1559, 1571, 6696, 9971 GO:0006874 BP e cellular calcium ion homeostasis 10/100 413/19669 4.810213098379911e-05 9 10 0.0010605899653877 348, 351, 581, 3064, 3146, 3627, 5663, 6622, 9104, 729230 GO:0006575 BP e cellular modified amino acid metabolic process 7/100 188/19669 4.9323057658121e-05 4 7 0.0010859540162496 1152, 1719, 2876, 2941, 2944, 2947, 4524 GO:0030808 BP e regulation of nucleotide biosynthetic process 4/100 40/19669 4.994451325481218e-05 8 4 0.0010933798847675 2023, 4846, 5166, 5465 GO:0051281 BP e positive regulation of release of sequestered calcium ion into cytosol 4/100 40/19669 4.994451325481218e-05 13 4 0.0010933798847675 581, 3064, 3627, 6622 GO:0001937 BP e negative regulation of endothelial cell proliferation 4/100 40/19669 4.994451325481218e-05 7 4 0.0010933798847675 348, 350, 5468, 6347 GO:0046006 BP e regulation of activated T cell proliferation 4/100 40/19669 4.994451325481218e-05 9 4 0.0010933798847675 383, 3146, 3479, 11035 GO:0055001 BP e muscle cell development 5/100 79/19669 5.138392276159787e-05 4 5 0.0011217001011361 2876, 3479, 4851, 7422, 9474 GO:0006110 BP e regulation of glycolytic process 5/100 79/19669 5.138392276159787e-05 9 5 0.0011217001011361 351, 3458, 3479, 5465, 5663 GO:0030857 BP e negative regulation of epithelial cell differentiation 4/100 41/19669 5.512874401133685e-05 6 4 0.0012017441506154 3458, 4318, 4851, 7422 GO:0051044 BP e positive regulation of membrane protein ectodomain proteolysis 3/100 15/19669 5.550083528055165e-05 9 3 0.0012064376482594 348, 3458, 3553 GO:0030224 BP e monocyte differentiation 3/100 15/19669 5.550083528055165e-05 6 3 0.0012064376482594 2194, 5468, 7422 GO:0043523 BP e regulation of neuron apoptotic process 7/100 192/19669 5.6353160081500966e-05 7 7 0.0012232371419665 348, 581, 2896, 3162, 5071, 5663, 6347 GO:0090407 BP e organophosphate biosynthetic process 11/100 510/19669 5.654840619437783e-05 5 11 0.001225746438495 335, 1152, 1737, 2180, 2194, 4199, 4831, 4860, 5130, 5836, 6652 GO:0031346 BP e positive regulation of cell projection organization 9/100 338/19669 5.664252459467908e-05 6 9 0.001226059709581 348, 2896, 3064, 3309, 4137, 4780, 4831, 7422, 10096 GO:0048513 BP e animal organ development 18/100 1256/19669 5.672923255787796e-05 3 18 0.0012262119228451 183, 335, 383, 581, 2194, 3146, 3162, 3479, 3569, 3627, 4851, 5465, 5468, 5591, 5663, 7422, 9104, 11035 GO:0044267 BP e cellular protein metabolic process 33/100 3225/19669 5.688122956269375e-05 5 33 0.001227772963492 60, 213, 335, 348, 351, 1356, 1737, 2081, 2243, 2876, 2934, 3479, 3569, 3654, 4137, 4217, 4313, 4780, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 6347, 6622, 6696, 7276, 9474, 9971, 11035, 23476 GO:1905897 BP e regulation of response to endoplasmic reticulum stress 5/100 81/19669 5.7948659042823645e-05 6 5 0.0012444772051468 581, 2081, 3309, 4780, 5071 GO:1902882 BP e regulation of response to oxidative stress 5/100 81/19669 5.7948659042823645e-05 5 5 0.0012444772051468 1719, 2876, 4780, 5071, 83667 GO:0019395 BP e fatty acid oxidation 5/100 81/19669 5.7948659042823645e-05 8 5 0.0012444772051468 3030, 5468, 9370, 26061, 83667 GO:0032675 BP e regulation of interleukin-6 production 6/100 132/19669 5.797856764719276e-05 7 6 0.0012444772051468 351, 3146, 3458, 3553, 3569, 9971 GO:0050767 BP e regulation of neurogenesis 9/100 340/19669 5.9272846281104647e-05 6 9 0.0012704862176409 3458, 3553, 3569, 4137, 4851, 5468, 5663, 6696, 7422 GO:0050671 BP e positive regulation of lymphocyte proliferation 6/100 133/19669 6.047037427771914e-05 8 6 0.0012925542501862 3146, 3479, 3553, 3569, 4860, 729230 GO:0002687 BP e positive regulation of leukocyte migration 6/100 133/19669 6.047037427771914e-05 8 6 0.0012925542501862 351, 3146, 3569, 3627, 7422, 729230 GO:0048662 BP e negative regulation of smooth muscle cell proliferation 4/100 42/19669 6.06948984310242e-05 6 4 0.0012955540733057 3162, 3458, 5468, 9370 GO:0055074 BP e calcium ion homeostasis 10/100 426/19669 6.231926668791388e-05 8 10 0.0013280867225604 348, 351, 581, 3064, 3146, 3627, 5663, 6622, 9104, 729230 GO:0110053 BP e regulation of actin filament organization 8/100 265/19669 6.239159846726615e-05 8 8 0.0013280867225604 335, 1440, 2934, 5071, 5580, 10096, 50507, 136319 GO:0032946 BP e positive regulation of mononuclear cell proliferation 6/100 134/19669 6.304705910918358e-05 7 6 0.0013401854139369 3146, 3479, 3553, 3569, 4860, 729230 GO:0017157 BP e regulation of exocytosis 7/100 196/19669 6.418374401413321e-05 7 7 0.0013624659591413 2243, 3162, 3458, 4851, 5071, 6622, 729230 GO:0032755 BP e positive regulation of interleukin-6 production 5/100 83/19669 6.514282075616366e-05 8 5 0.0013809201259467 351, 3146, 3458, 3553, 3569 GO:2000404 BP e regulation of T cell migration 4/100 43/19669 6.665989902800467e-05 10 4 0.0014111359642929 351, 3627, 11035, 729230 GO:0010631 BP e epithelial cell migration 5/100 84/19669 6.898858616578465e-05 6 5 0.0014564257079443 335, 2876, 3146, 4846, 7422 GO:0001816 BP e cytokine production 5/100 84/19669 6.898858616578465e-05 5 5 0.0014564257079443 3146, 3553, 3569, 4860, 9971 GO:0050708 BP e regulation of protein secretion 8/100 269/19669 6.928762443437835e-05 9 8 0.0014607349863631 348, 2243, 3458, 3479, 3553, 3569, 5071, 9971 GO:0006869 BP e lipid transport 9/100 349/19669 7.242277010048816e-05 7 9 0.0015247420408297 335, 348, 350, 1244, 2180, 5243, 5468, 5663, 9971 GO:0048013 BP e ephrin receptor signaling pathway 5/100 85/19669 7.300705266091275e-05 8 5 0.0015293871908769 60, 4313, 4318, 5663, 10096 GO:0006919 BP e activation of cysteine-type endopeptidase activity involved in apoptotic process 5/100 85/19669 7.300705266091275e-05 13 5 0.0015293871908769 581, 4137, 5468, 6622, 9131 GO:0034440 BP e lipid oxidation 5/100 85/19669 7.300705266091275e-05 6 5 0.0015293871908769 3030, 5468, 9370, 26061, 83667 GO:1904036 BP e negative regulation of epithelial cell apoptotic process 4/100 44/19669 7.304090872609202e-05 8 4 0.0015293871908769 2243, 3162, 4780, 5465 GO:0072521 BP e purine-containing compound metabolic process 9/100 350/19669 7.402479590710248e-05 4 9 0.0015478826209379 229, 1737, 2023, 2180, 2194, 2876, 4831, 4860, 7276 GO:0060326 BP e cell chemotaxis 7/100 201/19669 7.520189172369949e-05 5 7 0.0015703624336875 3146, 3569, 3627, 5580, 6347, 7422, 729230 GO:2000449 BP e regulation of CD8-positive, alpha-beta T cell extravasation 2/100 3/19669 7.651892343145596e-05 12 2 0.0015870973471834 11035, 729230 GO:0060948 BP e cardiac vascular smooth muscle cell development 2/100 3/19669 7.651892343145596e-05 6 2 0.0015870973471834 4851, 7422 GO:1902263 BP e apoptotic process involved in embryonic digit morphogenesis 2/100 3/19669 7.651892343145596e-05 7 2 0.0015870973471834 581, 4851 GO:0006808 BP e regulation of nitrogen utilization 2/100 3/19669 7.651892343145596e-05 3 2 0.0015870973471834 581, 9971 GO:0060559 BP e positive regulation of calcidiol 1-monooxygenase activity 2/100 3/19669 7.651892343145596e-05 7 2 0.0015870973471834 3458, 3553 GO:1902105 BP e regulation of leukocyte differentiation 8/100 273/19669 7.6806311955663e-05 6 8 0.0015909140524867 3146, 3440, 3458, 4831, 4860, 5591, 9370, 729230 GO:1903426 BP e regulation of reactive oxygen species biosynthetic process 5/100 86/19669 7.720350614366219e-05 6 5 0.0015969918811168 3458, 3553, 5465, 6622, 9104 GO:0042246 BP e tissue regeneration 4/100 45/19669 7.985532349560274e-05 4 4 0.0016496287632178 2876, 2934, 4851, 136319 GO:0042110 BP e T cell activation 7/100 203/19669 8.002064978791706e-05 5 7 0.0016508281504504 581, 3146, 3440, 3569, 5591, 5663, 11035 GO:2001267 BP e regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 3/100 17/19669 8.233534785684358e-05 11 3 0.0016895213380224 581, 2934, 4318 GO:0140467 BP e integrated stress response signaling 3/100 17/19669 8.233534785684358e-05 4 3 0.0016895213380224 3309, 4780, 6347 GO:0090201 BP e negative regulation of release of cytochrome c from mitochondria 3/100 17/19669 8.233534785684358e-05 9 3 0.0016895213380224 2876, 3479, 5071 GO:0010544 BP e negative regulation of platelet activation 3/100 17/19669 8.233534785684358e-05 9 3 0.0016895213380224 348, 4846, 5580 GO:0031056 BP e regulation of histone modification 6/100 141/19669 8.364205126642749e-05 8 6 0.0017094969043696 3553, 4524, 6622, 7422, 9474, 23476 GO:0030856 BP e regulation of epithelial cell differentiation 6/100 141/19669 8.364205126642749e-05 5 6 0.0017094969043696 3458, 3553, 4318, 4831, 4851, 7422 GO:1903169 BP e regulation of calcium ion transmembrane transport 6/100 141/19669 8.364205126642749e-05 8 6 0.0017094969043696 581, 3064, 3627, 6622, 9104, 9474 GO:0043687 BP e post-translational protein modification 9/100 357/19669 8.609707075725348e-05 7 9 0.0017570170729544 213, 335, 348, 351, 1356, 2243, 3569, 6696, 9474 GO:0072503 BP e cellular divalent inorganic cation homeostasis 10/100 443/19669 8.619544444968048e-05 8 10 0.0017570170729544 348, 351, 581, 3064, 3146, 3627, 5663, 6622, 9104, 729230 GO:0010212 BP e response to ionizing radiation 6/100 142/19669 8.697655678341235e-05 4 6 0.0017665198624248 581, 2876, 3309, 3627, 5591, 50507 GO:0048678 BP e response to axon injury 4/100 46/19669 8.712076514492845e-05 4 4 0.0017665198624248 335, 383, 581, 1719 GO:0010823 BP e negative regulation of mitochondrion organization 4/100 46/19669 8.712076514492845e-05 7 4 0.0017665198624248 2876, 3479, 4137, 5071 GO:0050999 BP e regulation of nitric-oxide synthase activity 4/100 46/19669 8.712076514492845e-05 6 4 0.0017665198624248 348, 1719, 3553, 4846 GO:0014074 BP e response to purine-containing compound 6/100 143/19669 9.041612194005348e-05 5 6 0.0018285205212318 196, 351, 3309, 5468, 9370, 50507 GO:0009411 BP e response to UV 6/100 143/19669 9.041612194005348e-05 5 6 0.0018285205212318 581, 847, 2876, 4313, 4318, 5580 GO:0042060 BP e wound healing 5/100 89/19669 9.091486767290826e-05 4 5 0.0018361939809528 2934, 3162, 3479, 4217, 5465 GO:0051223 BP e regulation of protein transport 11/100 538/19669 9.106285954883828e-05 8 11 0.0018367724881476 348, 2243, 3458, 3479, 3553, 3569, 5071, 5580, 5663, 9370, 9971 GO:0120161 BP e regulation of cold-induced thermogenesis 6/100 144/19669 9.396315069863855e-05 4 6 0.0018927917398587 2180, 3934, 4851, 7422, 9370, 729230 GO:0051402 BP e neuron apoptotic process 4/100 47/19669 9.4855074117169e-05 5 4 0.0019057697006047 351, 581, 3309, 5663 GO:0019319 BP e hexose biosynthetic process 4/100 47/19669 9.4855074117169e-05 6 4 0.0019057697006047 229, 2023, 5091, 6652 GO:1901655 BP e cellular response to ketone 5/100 90/19669 9.587775229796342e-05 5 5 0.0019238052253789 196, 383, 1244, 5468, 6696 GO:0070665 BP e positive regulation of leukocyte proliferation 6/100 145/19669 9.76200795397826e-05 6 6 0.0019562148751526 3146, 3479, 3553, 3569, 4860, 729230 GO:0032930 BP e positive regulation of superoxide anion generation 3/100 18/19669 9.843798689715594e-05 8 3 0.001962384220657 1401, 4137, 5580 GO:0033189 BP e response to vitamin A 3/100 18/19669 9.843798689715594e-05 7 3 0.001962384220657 383, 847, 5468 GO:0002281 BP e macrophage activation involved in immune response 3/100 18/19669 9.843798689715594e-05 6 3 0.001962384220657 2896, 3146, 3458 GO:0034375 BP e high-density lipoprotein particle remodeling 3/100 18/19669 9.843798689715594e-05 8 3 0.001962384220657 213, 335, 348 GO:0002690 BP e positive regulation of leukocyte chemotaxis 5/100 91/19669 0.0001010462681396 9 5 0.002009344975948 3146, 3569, 3627, 7422, 729230 GO:0070372 BP e regulation of ERK1 and ERK2 cascade 8/100 284/19669 0.0001010547765681 8 8 0.002009344975948 348, 351, 2243, 3146, 3553, 4851, 6347, 9370 GO:0015850 BP e organic hydroxy compound transport 6/100 146/19669 0.0001013893775816 7 6 0.0020133968012659 335, 348, 1244, 5071, 6622, 9971 GO:0090257 BP e regulation of muscle system process 7/100 211/19669 0.0001018862735911 5 7 0.0020206568950616 183, 2023, 3479, 4846, 4851, 5465, 136319 GO:2000191 BP e regulation of fatty acid transport 4/100 48/19669 0.0001030763024867 8 4 0.0020416271496413 2180, 3553, 5465, 5663 GO:0008217 BP e regulation of blood pressure 6/100 147/19669 0.0001052735465604 3 6 0.0020824677140948 183, 3162, 4846, 5465, 5468, 9370 GO:0051591 BP e response to cAMP 5/100 92/19669 0.0001064261841741 6 5 0.0020998704800508 196, 351, 3309, 9370, 50507 GO:2001243 BP e negative regulation of intrinsic apoptotic signaling pathway 5/100 92/19669 0.0001064261841741 9 5 0.0020998704800508 2023, 2876, 4318, 4780, 5071 GO:0048545 BP e response to steroid hormone 7/100 213/19669 0.0001080507693051 5 7 0.0021264723012863 383, 1244, 3146, 3569, 4851, 6696, 9370 GO:0050769 BP e positive regulation of neurogenesis 7/100 213/19669 0.0001080507693051 7 7 0.0021264723012863 3458, 3553, 3569, 4137, 4851, 5468, 7422 GO:0034605 BP e cellular response to heat 4/100 49/19669 0.0001118027070075 5 4 0.0021946985469983 3162, 3627, 3654, 4137 GO:0071827 BP e plasma lipoprotein particle organization 4/100 49/19669 0.0001118027070075 6 4 0.0021946985469983 183, 213, 335, 348 GO:0010522 BP e regulation of calcium ion transport into cytosol 5/100 93/19669 0.0001120233484177 8 5 0.0021962284485969 581, 3064, 3627, 6622, 9474 GO:0046483 BP e heterocycle metabolic process 29/100 2760/19669 0.000115681356139 3 29 0.0022650586144792 229, 351, 581, 1244, 1571, 1719, 1737, 2023, 2052, 2081, 2180, 2194, 2876, 3146, 3162, 4137, 4199, 4524, 4780, 4831, 4851, 4860, 5091, 5465, 5468, 5591, 7276, 9971, 83667 GO:1904706 BP e negative regulation of vascular associated smooth muscle cell proliferation 3/100 19/19669 0.0001164640354074 7 3 0.0022745958184278 3162, 5468, 9370 GO:0007263 BP e nitric oxide mediated signal transduction 3/100 19/19669 0.0001164640354074 7 3 0.0022745958184278 183, 348, 4846 GO:0032091 BP e negative regulation of protein binding 5/100 94/19669 0.0001178436874496 5 5 0.0022957143668981 60, 581, 5465, 5580, 9370 GO:0043255 BP e regulation of carbohydrate biosynthetic process 5/100 94/19669 0.0001178436874496 6 5 0.0022957143668981 3479, 5465, 6622, 9370, 83667 GO:1905953 BP e negative regulation of lipid localization 4/100 50/19669 0.0001210527421959 5 4 0.0023552486755947 1401, 3569, 5465, 5468 GO:0050920 BP e regulation of chemotaxis 7/100 217/19669 0.0001212915833527 5 7 0.0023569159946954 3146, 3569, 3627, 4851, 6347, 7422, 729230 GO:0031960 BP e response to corticosteroid 6/100 152/19669 0.0001265073074095 6 6 0.0024520748879505 383, 1244, 3146, 3569, 4851, 9370 GO:0009743 BP e response to carbohydrate 6/100 152/19669 0.0001265073074095 4 6 0.0024520748879505 847, 2081, 4199, 4831, 9370, 83667 GO:0051047 BP e positive regulation of secretion 8/100 294/19669 0.0001283027839469 6 8 0.002483748232634 2243, 3458, 3479, 3553, 6622, 6696, 9474, 9971 GO:0032271 BP e regulation of protein polymerization 7/100 221/19669 0.0001358225487592 6 7 0.002626016363574 1440, 2934, 4137, 5580, 6622, 10096, 136319 GO:1905562 BP e regulation of vascular endothelial cell proliferation 3/100 20/19669 0.0001365113433045 7 3 0.0026261369668211 3146, 5468, 6347 GO:0090026 BP e positive regulation of monocyte chemotaxis 3/100 20/19669 0.0001365113433045 10 3 0.0026261369668211 3146, 3627, 729230 GO:0032928 BP e regulation of superoxide anion generation 3/100 20/19669 0.0001365113433045 7 3 0.0026261369668211 1401, 4137, 5580 GO:1902176 BP e negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/100 20/19669 0.0001365113433045 10 3 0.0026261369668211 2876, 4780, 5071 GO:0120162 BP e positive regulation of cold-induced thermogenesis 5/100 97/19669 0.0001367041874946 5 5 0.0026265636024261 2180, 3934, 7422, 9370, 729230 GO:0002791 BP e regulation of peptide secretion 8/100 298/19669 0.0001407795051109 8 8 0.0026950352950406 348, 2243, 3458, 3479, 3553, 3569, 5071, 9971 GO:0032868 BP e response to insulin 6/100 155/19669 0.0001407932668754 7 6 0.0026950352950406 847, 5465, 5468, 5591, 9370, 83667 GO:0000187 BP e activation of MAPK activity 6/100 155/19669 0.0001407932668754 13 6 0.0026950352950406 183, 2081, 3479, 3553, 3654, 4217 GO:0010883 BP e regulation of lipid storage 4/100 52/19669 0.0001411984713549 4 4 0.0026994341293815 1401, 3569, 5465, 5468 GO:0045807 BP e positive regulation of endocytosis 5/100 98/19669 0.0001434780458279 7 5 0.0027396118179795 302, 348, 5468, 6622, 7422 GO:0045732 BP e positive regulation of protein catabolic process 7/100 224/19669 0.0001476231440375 7 7 0.0028152666502333 348, 3458, 3553, 4780, 5071, 5663, 9104 GO:0090087 BP e regulation of peptide transport 11/100 569/19669 0.0001489631992029 7 11 0.0028373064798679 348, 2243, 3458, 3479, 3553, 3569, 5071, 5580, 5663, 9370, 9971 GO:0071214 BP e cellular response to abiotic stimulus 8/100 301/19669 0.0001507806691974 4 8 0.0028419265486754 581, 3309, 3553, 4313, 4318, 5580, 50507, 136319 GO:0104004 BP e cellular response to environmental stimulus 8/100 301/19669 0.0001507806691974 3 8 0.0028419265486754 581, 3309, 3553, 4313, 4318, 5580, 50507, 136319 GO:0071825 BP e protein-lipid complex subunit organization 4/100 53/19669 0.0001521320030616 5 4 0.0028419265486754 183, 213, 335, 348 GO:0010524 BP e positive regulation of calcium ion transport into cytosol 4/100 53/19669 0.0001521320030616 12 4 0.0028419265486754 581, 3064, 3627, 6622 GO:0002704 BP e negative regulation of leukocyte mediated immunity 4/100 53/19669 0.0001521320030616 6 4 0.0028419265486754 383, 3162, 3440, 729230 GO:0046486 BP e glycerolipid metabolic process 9/100 385/19669 0.000152279740903 5 9 0.0028419265486754 335, 348, 350, 847, 1571, 2180, 2876, 3030, 5130 GO:0042158 BP e lipoprotein biosynthetic process 2/100 4/19669 0.0001525296510205 6 2 0.0028419265486754 335, 348 GO:1904747 BP e positive regulation of apoptotic process involved in development 2/100 4/19669 0.0001525296510205 8 2 0.0028419265486754 581, 4851 GO:0051450 BP e myoblast proliferation 2/100 4/19669 0.0001525296510205 3 2 0.0028419265486754 2876, 3479 GO:0010193 BP e response to ozone 2/100 4/19669 0.0001525296510205 5 2 0.0028419265486754 847, 1571 GO:0018916 BP e nitrobenzene metabolic process 2/100 4/19669 0.0001525296510205 5 2 0.0028419265486754 2944, 2947 GO:2000552 BP e negative regulation of T-helper 2 cell cytokine production 2/100 4/19669 0.0001525296510205 10 2 0.0028419265486754 383, 3440 GO:0010903 BP e negative regulation of very-low-density lipoprotein particle remodeling 2/100 4/19669 0.0001525296510205 6 2 0.0028419265486754 335, 9971 GO:0031427 BP e response to methotrexate 2/100 4/19669 0.0001525296510205 5 2 0.0028419265486754 1244, 1719 GO:1902512 BP e positive regulation of apoptotic DNA fragmentation 2/100 4/19669 0.0001525296510205 9 2 0.0028419265486754 581, 3569 GO:1902994 BP e regulation of phospholipid efflux 2/100 4/19669 0.0001525296510205 9 2 0.0028419265486754 335, 348 GO:1902339 BP e positive regulation of apoptotic process involved in morphogenesis 2/100 4/19669 0.0001525296510205 9 2 0.0028419265486754 581, 4851 GO:1902995 BP e positive regulation of phospholipid efflux 2/100 4/19669 0.0001525296510205 10 2 0.0028419265486754 335, 348 GO:0010804 BP e negative regulation of tumor necrosis factor-mediated signaling pathway 3/100 21/19669 0.0001586761672957 8 3 0.0029316040992583 335, 9370, 9971 GO:1903306 BP e negative regulation of regulated secretory pathway 3/100 21/19669 0.0001586761672957 9 3 0.0029316040992583 3162, 4851, 729230 GO:0030810 BP e positive regulation of nucleotide biosynthetic process 3/100 21/19669 0.0001586761672957 9 3 0.0029316040992583 2023, 4846, 5465 GO:0045723 BP e positive regulation of fatty acid biosynthetic process 3/100 21/19669 0.0001586761672957 8 3 0.0029316040992583 335, 3553, 9104 GO:1900373 BP e positive regulation of purine nucleotide biosynthetic process 3/100 21/19669 0.0001586761672957 10 3 0.0029316040992583 2023, 4846, 5465 GO:0010875 BP e positive regulation of cholesterol efflux 3/100 21/19669 0.0001586761672957 11 3 0.0029316040992583 335, 348, 9370 GO:0050765 BP e negative regulation of phagocytosis 3/100 21/19669 0.0001586761672957 7 3 0.0029316040992583 3146, 9370, 9474 GO:0048639 BP e positive regulation of developmental growth 6/100 159/19669 0.0001617988649018 5 6 0.002985712866714 3479, 4137, 4851, 5071, 5591, 7422 GO:2000378 BP e negative regulation of reactive oxygen species metabolic process 4/100 54/19669 0.0001636648278558 6 4 0.003012920694619 5071, 5465, 9104, 9474 GO:0032731 BP e positive regulation of interleukin-1 beta production 4/100 54/19669 0.0001636648278558 9 4 0.003012920694619 351, 3146, 3458, 3569 GO:0002253 BP e activation of immune response 9/100 390/19669 0.000167706926429 6 9 0.0030836434859539 60, 581, 1401, 3075, 3146, 5580, 5591, 5663, 10096 GO:0009636 BP e response to toxic substance 5/100 102/19669 0.0001731774171967 3 5 0.0031804301320501 196, 383, 581, 2052, 5071 GO:0032870 BP e cellular response to hormone stimulus 8/100 308/19669 0.0001764138767541 5 8 0.0032360066308061 383, 1244, 4780, 4851, 5468, 5580, 5591, 9370 GO:0016310 BP e phosphorylation 14/100 900/19669 0.0001806289916254 5 14 0.0033093811679956 229, 351, 1152, 2023, 2081, 3654, 4217, 4831, 5166, 5580, 5591, 6347, 11035, 23476 GO:1901685 BP e glutathione derivative metabolic process 3/100 22/19669 0.0001830531869312 4 3 0.0033328282928256 2941, 2944, 2947 GO:0010288 BP e response to lead ion 3/100 22/19669 0.0001830531869312 5 3 0.0033328282928256 351, 847, 4137 GO:1901687 BP e glutathione derivative biosynthetic process 3/100 22/19669 0.0001830531869312 5 3 0.0033328282928256 2941, 2944, 2947 GO:0003015 BP e heart process 3/100 22/19669 0.0001830531869312 4 3 0.0033328282928256 2876, 9474, 50507 GO:0051924 BP e regulation of calcium ion transport 7/100 232/19669 0.0001832081049857 7 7 0.0033328282928256 581, 3064, 3627, 6347, 6622, 9104, 9474 GO:0010951 BP e negative regulation of endopeptidase activity 7/100 232/19669 0.0001832081049857 10 7 0.0033328282928256 183, 302, 351, 2876, 4318, 6622, 7422 GO:0071375 BP e cellular response to peptide hormone stimulus 6/100 163/19669 0.0001852111749505 7 6 0.0033652892355238 383, 4780, 5468, 5580, 5591, 9370 GO:0045088 BP e regulation of innate immune response 8/100 311/19669 0.0001884469698881 6 8 0.0034108633008215 348, 383, 2896, 3146, 3458, 5468, 5580, 5591 GO:0070997 BP e neuron death 4/100 56/19669 0.0001886058914229 3 4 0.0034108633008215 351, 581, 3309, 5663 GO:0032374 BP e regulation of cholesterol transport 4/100 56/19669 0.0001886058914229 9 4 0.0034108633008215 302, 335, 348, 9370 GO:0032371 BP e regulation of sterol transport 4/100 56/19669 0.0001886058914229 8 4 0.0034108633008215 302, 335, 348, 9370 GO:0001889 BP e liver development 5/100 104/19669 0.0001896807144064 5 5 0.0034262748764257 383, 3162, 3569, 4851, 9104 GO:0030968 BP e endoplasmic reticulum unfolded protein response 5/100 105/19669 0.0001983690935057 5 5 0.0035706436831026 821, 2081, 3309, 4780, 6347 GO:0120254 BP e olefinic compound metabolic process 5/100 105/19669 0.0001983690935057 3 5 0.0035706436831026 1559, 1571, 2052, 2180, 2876 GO:0032649 BP e regulation of interferon-gamma production 5/100 105/19669 0.0001983690935057 7 5 0.0035706436831026 3146, 3553, 9971, 11035, 729230 GO:0032757 BP e positive regulation of interleukin-8 production 4/100 57/19669 0.000202053287886 8 4 0.0036284715292486 3146, 3553, 3569, 9370 GO:1902041 BP e regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/100 57/19669 0.000202053287886 9 4 0.0036284715292486 2243, 2876, 3162, 4846 GO:0050804 BP e modulation of chemical synaptic transmission 9/100 400/19669 0.0002024971977327 6 9 0.0036322049803117 348, 351, 3553, 4137, 5071, 5663, 6347, 9370, 729230 GO:0043409 BP e negative regulation of MAPK cascade 6/100 166/19669 0.0002044654042798 8 6 0.0036632393153273 183, 348, 3553, 5071, 5580, 9370 GO:0099177 BP e regulation of trans-synaptic signaling 9/100 401/19669 0.0002062845539332 5 9 0.0036915340523641 348, 351, 3553, 4137, 5071, 5663, 6347, 9370, 729230 GO:0071674 BP e mononuclear cell migration 5/100 106/19669 0.0002073577064137 6 5 0.0037064286895551 3146, 3569, 3627, 6347, 729230 GO:1900120 BP e regulation of receptor binding 3/100 23/19669 0.0002097355204828 5 3 0.0037315949829253 302, 4318, 9370 GO:0001919 BP e regulation of receptor recycling 3/100 23/19669 0.0002097355204828 5 3 0.0037315949829253 302, 5663, 6622 GO:0030225 BP e macrophage differentiation 3/100 23/19669 0.0002097355204828 6 3 0.0037315949829253 3458, 4318, 7422 GO:0051043 BP e regulation of membrane protein ectodomain proteolysis 3/100 23/19669 0.0002097355204828 7 3 0.0037315949829253 348, 3458, 3553 GO:0035306 BP e positive regulation of dephosphorylation 4/100 58/19669 0.0002161782805203 8 4 0.0038329305728204 3458, 5580, 9104, 11035 GO:0014910 BP e regulation of smooth muscle cell migration 4/100 58/19669 0.0002161782805203 7 4 0.0038329305728204 3479, 4780, 9370, 50507 GO:0019369 BP e arachidonic acid metabolic process 4/100 58/19669 0.0002161782805203 9 4 0.0038329305728204 1559, 1571, 2052, 2876 GO:0071478 BP e cellular response to radiation 6/100 168/19669 0.0002181553323627 5 6 0.003863533446563 581, 3309, 4313, 4318, 5580, 50507 GO:0043122 BP e regulation of I-kappaB kinase/NF-kappaB signaling 7/100 239/19669 0.0002197656403646 7 7 0.0038875783967944 3162, 3553, 3654, 5071, 9370, 9971, 23476 GO:0009890 BP e negative regulation of biosynthetic process 19/100 1530/19669 0.000227510013303 5 19 0.0040199530479144 196, 348, 1719, 2023, 3146, 3440, 3458, 3569, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971, 83667 GO:1903706 BP e regulation of hemopoiesis 9/100 407/19669 0.0002302696912106 5 9 0.0040623016089802 1440, 3146, 3440, 3458, 4831, 4860, 5591, 9370, 729230 GO:0014015 BP e positive regulation of gliogenesis 4/100 59/19669 0.0002310008109341 8 4 0.0040623016089802 3553, 3569, 4851, 5468 GO:0002286 BP e T cell activation involved in immune response 4/100 59/19669 0.0002310008109341 6 4 0.0040623016089802 3146, 3440, 3569, 5663 GO:0010466 BP e negative regulation of peptidase activity 7/100 241/19669 0.0002312265243318 9 7 0.0040623016089802 183, 302, 351, 2876, 4318, 6622, 7422 GO:0010959 BP e regulation of metal ion transport 7/100 241/19669 0.0002312265243318 6 7 0.0040623016089802 581, 3064, 3627, 6347, 6622, 9104, 9474 GO:0045927 BP e positive regulation of growth 7/100 242/19669 0.0002371351477463 4 7 0.0041613568116489 3479, 4137, 4851, 5071, 5591, 7422, 136319 GO:0051493 BP e regulation of cytoskeleton organization 10/100 502/19669 0.0002380269170115 6 10 0.0041722485795072 335, 1440, 2934, 4137, 5071, 5580, 6622, 10096, 50507, 136319 GO:0050820 BP e positive regulation of coagulation 3/100 24/19669 0.0002388147407415 5 3 0.0041765441591052 350, 4780, 5663 GO:0010661 BP e positive regulation of muscle cell apoptotic process 3/100 24/19669 0.0002388147407415 8 3 0.0041765441591052 3458, 4217, 5468 GO:0055086 BP e nucleobase-containing small molecule metabolic process 10/100 504/19669 0.000245708453374 5 10 0.0042922282604168 229, 1737, 2023, 2180, 2194, 2876, 4199, 4831, 4860, 7276 GO:0050994 BP e regulation of lipid catabolic process 4/100 60/19669 0.000246540955035 6 4 0.0042970161925126 335, 3553, 5465, 5580 GO:0010803 BP e regulation of tumor necrosis factor-mediated signaling pathway 4/100 60/19669 0.000246540955035 7 4 0.0042970161925126 335, 5071, 9370, 9971 GO:2001257 BP e regulation of cation channel activity 6/100 172/19669 0.0002476999916957 8 6 0.0043074608725404 351, 3064, 3458, 4318, 6347, 729230 GO:0045619 BP e regulation of lymphocyte differentiation 6/100 172/19669 0.0002476999916957 7 6 0.0043074608725404 3146, 3440, 3458, 4860, 5591, 729230 GO:0120036 BP e plasma membrane bounded cell projection organization 11/100 605/19669 0.0002530719604047 5 11 0.0043278563107796 335, 348, 351, 1719, 2934, 3146, 3569, 4137, 4851, 5663, 10096 GO:1903596 BP e regulation of gap junction assembly 2/100 5/19669 0.0002533722245622 6 2 0.0043278563107796 183, 3553 GO:1905599 BP e positive regulation of low-density lipoprotein receptor activity 2/100 5/19669 0.0002533722245622 4 2 0.0043278563107796 302, 5468 GO:0051583 BP e dopamine uptake involved in synaptic transmission 2/100 5/19669 0.0002533722245622 11 2 0.0043278563107796 5071, 6622 GO:0060354 BP e negative regulation of cell adhesion molecule production 2/100 5/19669 0.0002533722245622 5 2 0.0043278563107796 335, 4851 GO:0051410 BP e detoxification of nitrogen compound 2/100 5/19669 0.0002533722245622 2 2 0.0043278563107796 2944, 2947 GO:0070458 BP e cellular detoxification of nitrogen compound 2/100 5/19669 0.0002533722245622 3 2 0.0043278563107796 2944, 2947 GO:0051934 BP e catecholamine uptake involved in synaptic transmission 2/100 5/19669 0.0002533722245622 10 2 0.0043278563107796 5071, 6622 GO:1903626 BP e positive regulation of DNA catabolic process 2/100 5/19669 0.0002533722245622 8 2 0.0043278563107796 581, 3569 GO:1904504 BP e positive regulation of lipophagy 2/100 5/19669 0.0002533722245622 9 2 0.0043278563107796 3064, 83667 GO:0010891 BP e negative regulation of sequestering of triglyceride 2/100 5/19669 0.0002533722245622 7 2 0.0043278563107796 5465, 5468 GO:1904502 BP e regulation of lipophagy 2/100 5/19669 0.0002533722245622 8 2 0.0043278563107796 3064, 83667 GO:1905563 BP e negative regulation of vascular endothelial cell proliferation 2/100 5/19669 0.0002533722245622 8 2 0.0043278563107796 5468, 6347 GO:1990962 BP e xenobiotic transport across blood-brain barrier 2/100 5/19669 0.0002533722245622 7 2 0.0043278563107796 1244, 5243 GO:0036091 BP e positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress 2/100 5/19669 0.0002533722245622 13 2 0.0043278563107796 4780, 83667 GO:2000407 BP e regulation of T cell extravasation 2/100 5/19669 0.0002533722245622 11 2 0.0043278563107796 11035, 729230 GO:0006935 BP e chemotaxis 8/100 325/19669 0.0002538933206084 3 8 0.0043319492285635 335, 3146, 3569, 3627, 5580, 6347, 7422, 729230 GO:0006690 BP e icosanoid metabolic process 5/100 111/19669 0.0002570482163326 6 5 0.0043809214278613 1559, 1571, 2052, 2876, 2944 GO:0051960 BP e regulation of nervous system development 9/100 414/19669 0.0002611415701144 5 9 0.0044457619071473 3458, 3553, 3569, 4137, 4851, 5468, 5663, 6696, 7422 GO:0031175 BP e neuron projection development 7/100 246/19669 0.0002620002869492 6 7 0.0044554523935355 335, 348, 351, 1719, 3146, 3569, 4137 GO:0032732 BP e positive regulation of interleukin-1 production 4/100 61/19669 0.0002628189171867 8 4 0.0044595183412391 351, 3146, 3458, 3569 GO:0046824 BP e positive regulation of nucleocytoplasmic transport 4/100 61/19669 0.0002628189171867 7 4 0.0044595183412391 3458, 3553, 5580, 5663 GO:0042330 BP e taxis 8/100 327/19669 0.0002646030016777 2 8 0.00448484603064 335, 3146, 3569, 3627, 5580, 6347, 7422, 729230 GO:0060334 BP e regulation of interferon-gamma-mediated signaling pathway 3/100 25/19669 0.0002703808906757 8 3 0.0045477179316938 383, 3458, 5468 GO:0048873 BP e homeostasis of number of cells within a tissue 3/100 25/19669 0.0002703808906757 6 3 0.0045477179316938 581, 4846, 4851 GO:0060330 BP e regulation of response to interferon-gamma 3/100 25/19669 0.0002703808906757 7 3 0.0045477179316938 383, 3458, 5468 GO:0032469 BP e endoplasmic reticulum calcium ion homeostasis 3/100 25/19669 0.0002703808906757 10 3 0.0045477179316938 351, 581, 5663 GO:0097300 BP e programmed necrotic cell death 3/100 25/19669 0.0002703808906757 4 3 0.0045477179316938 4217, 5836, 11035 GO:0071353 BP e cellular response to interleukin-4 3/100 25/19669 0.0002703808906757 6 3 0.0045477179316938 383, 2194, 3309 GO:0042537 BP e benzene-containing compound metabolic process 3/100 25/19669 0.0002703808906757 4 3 0.0045477179316938 1571, 2944, 2947 GO:0032872 BP e regulation of stress-activated MAPK cascade 6/100 175/19669 0.0002718570356426 8 6 0.0045675543433846 351, 3146, 3553, 4217, 5071, 7422 GO:0032874 BP e positive regulation of stress-activated MAPK cascade 5/100 113/19669 0.000279272912601 9 5 0.0046819282406639 351, 3146, 3553, 4217, 7422 GO:0051282 BP e regulation of sequestering of calcium ion 5/100 113/19669 0.000279272912601 4 5 0.0046819282406639 581, 3064, 3627, 6622, 9474 GO:0006749 BP e glutathione metabolic process 4/100 62/19669 0.0002798550244482 6 4 0.0046865819654609 2876, 2941, 2944, 2947 GO:0002695 BP e negative regulation of leukocyte activation 6/100 176/19669 0.0002803081582589 6 6 0.004689067995223 383, 2896, 3146, 3162, 3440, 729230 GO:0006163 BP e purine nucleotide metabolic process 8/100 330/19669 0.0002813596318861 8 8 0.0047015469432448 229, 1737, 2023, 2180, 2194, 2876, 4831, 4860 GO:0072329 BP e monocarboxylic acid catabolic process 5/100 114/19669 0.0002909176258944 7 5 0.0048559894387363 3030, 6652, 9370, 26061, 83667 GO:0009117 BP e nucleotide metabolic process 9/100 421/19669 0.0002953770104023 7 9 0.0049197534524803 229, 1737, 2023, 2180, 2194, 2876, 4199, 4831, 4860 GO:0010975 BP e regulation of neuron projection development 9/100 421/19669 0.0002953770104023 7 9 0.0049197534524803 348, 2896, 3309, 4137, 4780, 4831, 5663, 6696, 7422 GO:1903362 BP e regulation of cellular protein catabolic process 7/100 251/19669 0.0002959919550598 7 7 0.0049246661495897 302, 348, 2876, 4780, 5071, 5663, 9104 GO:0071677 BP e positive regulation of mononuclear cell migration 4/100 63/19669 0.0002976697207162 9 4 0.0049445464995729 351, 3146, 3627, 729230 GO:0070302 BP e regulation of stress-activated protein kinase signaling cascade 6/100 178/19669 0.0002978294090386 7 6 0.0049445464995729 351, 3146, 3553, 4217, 5071, 7422 GO:0070304 BP e positive regulation of stress-activated protein kinase signaling cascade 5/100 115/19669 0.0003029271550946 8 5 0.0050237596087349 351, 3146, 3553, 4217, 7422 GO:0070265 BP e necrotic cell death 3/100 26/19669 0.0003045224989504 3 3 0.0050339433499968 4217, 5836, 11035 GO:1900745 BP e positive regulation of p38MAPK cascade 3/100 26/19669 0.0003045224989504 10 3 0.0050339433499968 3553, 4217, 7422 GO:1901623 BP e regulation of lymphocyte chemotaxis 3/100 26/19669 0.0003045224989504 10 3 0.0050339433499968 3627, 6347, 729230 GO:1901605 BP e alpha-amino acid metabolic process 6/100 180/19669 0.0003161995868161 7 6 0.0052213644217812 383, 1719, 4143, 4524, 4846, 50507 GO:0001101 BP e response to acid chemical 5/100 117/19669 0.0003280707694993 3 5 0.0054057913732277 383, 4313, 4524, 7422, 83667 GO:1904950 BP e negative regulation of establishment of protein localization 5/100 117/19669 0.0003280707694993 6 5 0.0054057913732277 348, 3553, 4137, 5071, 9370 GO:1903036 BP e positive regulation of response to wounding 4/100 65/19669 0.0003357172077321 6 4 0.0055258693336878 350, 2896, 3146, 4780 GO:1901135 BP e carbohydrate derivative metabolic process 13/100 842/19669 0.0003361478810856 3 13 0.0055270468909282 229, 581, 1737, 2023, 2180, 2194, 3479, 3553, 4831, 4860, 5836, 6652, 6888 GO:0008203 BP e cholesterol metabolic process 5/100 118/19669 0.0003412200692297 6 5 0.0055823765167608 335, 348, 351, 847, 1559 GO:0010613 BP e positive regulation of cardiac muscle hypertrophy 3/100 27/19669 0.0003413265953393 8 3 0.0055823765167608 183, 3479, 136319 GO:0071280 BP e cellular response to copper ion 3/100 27/19669 0.0003413265953393 6 3 0.0055823765167608 351, 4780, 6622 GO:0072376 BP e protein activation cascade 3/100 27/19669 0.0003413265953393 5 3 0.0055823765167608 350, 2243, 7450 GO:0090025 BP e regulation of monocyte chemotaxis 3/100 27/19669 0.0003413265953393 9 3 0.0055823765167608 3146, 3627, 729230 GO:0046649 BP e lymphocyte activation 8/100 341/19669 0.0003504080226493 4 8 0.0057231221739346 581, 3146, 3440, 3569, 5580, 5591, 5663, 11035 GO:0006753 BP e nucleoside phosphate metabolic process 9/100 431/19669 0.0003506760370383 6 9 0.0057231221739346 229, 1737, 2023, 2180, 2194, 2876, 4199, 4831, 4860 GO:1902275 BP e regulation of chromatin organization 6/100 184/19669 0.0003556022260127 5 6 0.0057914460590811 3553, 4524, 6622, 7422, 9474, 23476 GO:0042531 BP e positive regulation of tyrosine phosphorylation of STAT protein 4/100 66/19669 0.0003559914211754 11 4 0.0057914460590811 3440, 3458, 3479, 3569 GO:0050848 BP e regulation of calcium-mediated signaling 4/100 66/19669 0.0003559914211754 7 4 0.0057914460590811 3064, 3479, 4137, 9104 GO:0051962 BP e positive regulation of nervous system development 7/100 259/19669 0.0003576822141105 6 7 0.0058128081047102 3458, 3553, 3569, 4137, 4851, 5468, 7422 GO:0032956 BP e regulation of actin cytoskeleton organization 8/100 343/19669 0.0003643344836273 7 8 0.0059146705728118 335, 1440, 2934, 5071, 5580, 10096, 50507, 136319 GO:0051346 BP e negative regulation of hydrolase activity 9/100 435/19669 0.0003750701041763 5 9 0.0060789252551348 183, 302, 335, 351, 2876, 4318, 6622, 7422, 9104 GO:1901224 BP e positive regulation of NIK/NF-kappaB signaling 4/100 67/19669 0.0003771270583268 8 4 0.0060789252551348 351, 3146, 3553, 3654 GO:0051052 BP e regulation of DNA metabolic process 8/100 345/19669 0.0003787094088144 6 8 0.0060789252551348 581, 3146, 3569, 5468, 5580, 5591, 9104, 9370 GO:0030644 BP e cellular chloride ion homeostasis 2/100 6/19669 0.0003787972267494 9 2 0.0060789252551348 1152, 1244 GO:2000121 BP e regulation of removal of superoxide radicals 2/100 6/19669 0.0003787972267494 7 2 0.0060789252551348 1719, 4780 GO:1904753 BP e negative regulation of vascular associated smooth muscle cell migration 2/100 6/19669 0.0003787972267494 9 2 0.0060789252551348 4780, 9370 GO:0010901 BP e regulation of very-low-density lipoprotein particle remodeling 2/100 6/19669 0.0003787972267494 5 2 0.0060789252551348 335, 9971 GO:0030320 BP e cellular monovalent inorganic anion homeostasis 2/100 6/19669 0.0003787972267494 8 2 0.0060789252551348 1152, 1244 GO:0035234 BP e ectopic germ cell programmed cell death 2/100 6/19669 0.0003787972267494 5 2 0.0060789252551348 581, 5591 GO:0016098 BP e monoterpenoid metabolic process 2/100 6/19669 0.0003787972267494 7 2 0.0060789252551348 1559, 1571 GO:0032803 BP e regulation of low-density lipoprotein particle receptor catabolic process 2/100 6/19669 0.0003787972267494 8 2 0.0060789252551348 302, 348 GO:1902175 BP e regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/100 28/19669 0.0003808787259054 9 3 0.0060869403859663 2876, 4780, 5071 GO:1901031 BP e regulation of response to reactive oxygen species 3/100 28/19669 0.0003808787259054 6 3 0.0060869403859663 1719, 4780, 83667 GO:0014742 BP e positive regulation of muscle hypertrophy 3/100 28/19669 0.0003808787259054 7 3 0.0060869403859663 183, 3479, 136319 GO:0035924 BP e cellular response to vascular endothelial growth factor stimulus 3/100 28/19669 0.0003808787259054 6 3 0.0060869403859663 2081, 4851, 7422 GO:0046394 BP e carboxylic acid biosynthetic process 7/100 263/19669 0.000392177037849 6 7 0.0062610006353694 1559, 1571, 1719, 2194, 2944, 4524, 9104 GO:0048872 BP e homeostasis of number of cells 5/100 122/19669 0.0003978476523809 4 5 0.0063383803003546 581, 3162, 4846, 4851, 11035 GO:0050680 BP e negative regulation of epithelial cell proliferation 5/100 122/19669 0.0003978476523809 6 5 0.0063383803003546 348, 350, 5468, 6347, 9104 GO:0006357 BP e regulation of transcription by RNA polymerase II 26/100 2514/19669 0.0003988745877623 10 26 0.0063459117330698 196, 348, 351, 1440, 2023, 3146, 3162, 3309, 3458, 3479, 3569, 3627, 4780, 4831, 4851, 5071, 5465, 5468, 5591, 5663, 6622, 7422, 9971, 10096, 23476, 83667 GO:0006986 BP e response to unfolded protein 4/100 68/19669 0.0003991450654718 5 4 0.0063459117330698 581, 2081, 3309, 5071 GO:0060251 BP e regulation of glial cell proliferation 3/100 29/19669 0.0004232629682734 5 3 0.0067016636643295 3553, 3569, 4851 GO:0072678 BP e T cell migration 3/100 29/19669 0.0004232629682734 8 3 0.0067016636643295 3627, 6347, 729230 GO:0070670 BP e response to interleukin-4 3/100 29/19669 0.0004232629682734 5 3 0.0067016636643295 383, 2194, 3309 GO:1900101 BP e regulation of endoplasmic reticulum unfolded protein response 3/100 29/19669 0.0004232629682734 7 3 0.0067016636643295 581, 2081, 3309 GO:0006721 BP e terpenoid metabolic process 5/100 124/19669 0.000428689866007 6 5 0.0067806136051886 335, 348, 1559, 1571, 7276 GO:0043154 BP e negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/100 70/19669 0.0004459123922841 12 4 0.0070385556074388 2876, 4318, 6622, 7422 GO:2001259 BP e positive regulation of cation channel activity 4/100 70/19669 0.0004459123922841 9 4 0.0070385556074388 3064, 3458, 6347, 729230 GO:0001525 BP e angiogenesis 7/100 269/19669 0.0004488680625935 3 7 0.0070779502902815 302, 2876, 3162, 4313, 4851, 6347, 7422 GO:0043903 BP e regulation of biological process involved in symbiotic interaction 6/100 193/19669 0.0004583316282403 3 6 0.0072143184637007 383, 2934, 3440, 4851, 5091, 5465 GO:0016053 BP e organic acid biosynthetic process 7/100 270/19669 0.0004589225325512 4 7 0.0072143184637007 1559, 1571, 1719, 2194, 2944, 4524, 9104 GO:1903532 BP e positive regulation of secretion by cell 7/100 270/19669 0.0004589225325512 7 7 0.0072143184637007 2243, 3458, 3479, 3553, 6622, 6696, 9971 GO:0055076 BP e transition metal ion homeostasis 5/100 126/19669 0.0004613030804973 8 5 0.007244341233524 351, 1356, 3162, 3934, 5071 GO:2000406 BP e positive regulation of T cell migration 3/100 30/19669 0.0004685619466114 11 3 0.0073327458992381 351, 3627, 729230 GO:0043534 BP e blood vessel endothelial cell migration 3/100 30/19669 0.0004685619466114 8 3 0.0073327458992381 335, 2876, 7422 GO:0090183 BP e regulation of kidney development 3/100 30/19669 0.0004685619466114 4 3 0.0073327458992381 183, 7422, 9370 GO:1903827 BP e regulation of cellular protein localization 10/100 547/19669 0.0004688383342982 5 10 0.0073327458992381 60, 2934, 3458, 3553, 4137, 5071, 5580, 5663, 9370, 83667 GO:1902652 BP e secondary alcohol metabolic process 5/100 127/19669 0.0004782941520211 5 5 0.0074730426391927 335, 348, 351, 847, 1559 GO:0015849 BP e organic acid transport 7/100 272/19669 0.000479571431075 7 7 0.0074853999231697 348, 1244, 2180, 5243, 5468, 5663, 9971 GO:0046328 BP e regulation of JNK cascade 5/100 128/19669 0.0004957524934588 9 5 0.0077301224663955 351, 3146, 3553, 4217, 5071 GO:1900407 BP e regulation of cellular response to oxidative stress 4/100 72/19669 0.0004964625703003 6 4 0.0077333592681401 1719, 2876, 4780, 5071 GO:0046683 BP e response to organophosphorus 5/100 129/19669 0.0005136863942929 4 5 0.0079774304825115 196, 351, 3309, 9370, 50507 GO:0050768 BP e negative regulation of neurogenesis 5/100 129/19669 0.0005136863942929 7 5 0.0079774304825115 3553, 3569, 4851, 5663, 6696 GO:0034284 BP e response to monosaccharide 5/100 129/19669 0.0005136863942929 5 5 0.0079774304825115 847, 2081, 4831, 9370, 83667 GO:0097421 BP e liver regeneration 3/100 31/19669 0.0005168568463754 6 3 0.0079783619515728 3162, 3569, 9104 GO:0031670 BP e cellular response to nutrient 3/100 31/19669 0.0005168568463754 6 3 0.0079783619515728 3162, 5468, 9971 GO:0010874 BP e regulation of cholesterol efflux 3/100 31/19669 0.0005168568463754 10 3 0.0079783619515728 335, 348, 9370 GO:0010574 BP e regulation of vascular endothelial growth factor production 3/100 31/19669 0.0005168568463754 7 3 0.0079783619515728 3553, 3569, 729230 GO:0007259 BP e receptor signaling pathway via JAK-STAT 3/100 31/19669 0.0005168568463754 7 3 0.0079783619515728 3458, 6347, 729230 GO:2000193 BP e positive regulation of fatty acid transport 3/100 31/19669 0.0005168568463754 9 3 0.0079783619515728 2180, 3553, 5663 GO:0010827 BP e regulation of glucose transmembrane transport 4/100 73/19669 0.0005232094015477 8 4 0.0080683293485173 3479, 3553, 4780, 9370 GO:0060336 BP e negative regulation of interferon-gamma-mediated signaling pathway 2/100 7/19669 0.0005285570904716 9 2 0.0080859777558242 383, 5468 GO:0150003 BP e regulation of spontaneous synaptic transmission 2/100 7/19669 0.0005285570904716 7 2 0.0080859777558242 351, 5071 GO:0060331 BP e negative regulation of response to interferon-gamma 2/100 7/19669 0.0005285570904716 8 2 0.0080859777558242 383, 5468 GO:0032489 BP e regulation of Cdc42 protein signal transduction 2/100 7/19669 0.0005285570904716 10 2 0.0080859777558242 335, 348 GO:0010573 BP e vascular endothelial growth factor production 2/100 7/19669 0.0005285570904716 6 2 0.0080859777558242 3553, 3569 GO:0060558 BP e regulation of calcidiol 1-monooxygenase activity 2/100 7/19669 0.0005285570904716 6 2 0.0080859777558242 3458, 3553 GO:0070841 BP e inclusion body assembly 2/100 7/19669 0.0005285570904716 5 2 0.0080859777558242 4137, 5071 GO:0034392 BP e negative regulation of smooth muscle cell apoptotic process 2/100 7/19669 0.0005285570904716 9 2 0.0080859777558242 350, 3479 GO:0006464 BP e cellular protein modification process 28/100 2884/19669 0.0005329446317328 6 28 0.0081369225023502 60, 213, 335, 348, 351, 1356, 1737, 2081, 2243, 2876, 3569, 3654, 4137, 4217, 4780, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 6347, 6696, 9474, 9971, 11035, 23476 GO:0036211 BP e protein modification process 28/100 2884/19669 0.0005329446317328 5 28 0.0081369225023502 60, 213, 335, 348, 351, 1356, 1737, 2081, 2243, 2876, 3569, 3654, 4137, 4217, 4780, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 6347, 6696, 9474, 9971, 11035, 23476 GO:0051258 BP e protein polymerization 4/100 74/19669 0.0005509658783081 7 4 0.0083961486401432 2243, 2934, 4137, 5071 GO:0031333 BP e negative regulation of protein-containing complex assembly 5/100 131/19669 0.0005510143032192 6 5 0.0083961486401432 2934, 3146, 3309, 5580, 6622 GO:0070374 BP e positive regulation of ERK1 and ERK2 cascade 6/100 200/19669 0.0005531650889423 9 6 0.0084122635561492 348, 351, 2243, 3146, 4851, 6347 GO:0030100 BP e regulation of endocytosis 6/100 200/19669 0.0005531650889423 6 6 0.0084122635561492 302, 348, 5468, 6622, 7422, 9370 GO:0006468 BP e protein phosphorylation 11/100 665/19669 0.0005616967294056 7 11 0.0085335761752749 351, 2081, 3654, 4217, 4831, 5166, 5580, 5591, 6347, 11035, 23476 GO:1904037 BP e positive regulation of epithelial cell apoptotic process 3/100 32/19669 0.0005682274293261 8 3 0.0086073032847738 2934, 3569, 6347 GO:0097696 BP e receptor signaling pathway via STAT 3/100 32/19669 0.0005682274293261 6 3 0.0086073032847738 3458, 6347, 729230 GO:0042759 BP e long-chain fatty acid biosynthetic process 3/100 32/19669 0.0005682274293261 9 3 0.0086073032847738 1559, 1571, 2944 GO:0051495 BP e positive regulation of cytoskeleton organization 6/100 202/19669 0.000582880554959 7 6 0.0088205818493798 335, 1440, 2934, 4137, 10096, 50507 GO:0006091 BP e generation of precursor metabolites and energy 8/100 370/19669 0.0006008494275879 3 8 0.009083568458329 229, 847, 2023, 4199, 5836, 6888, 9370, 50507 GO:0016125 BP e sterol metabolic process 5/100 134/19669 0.0006107831827769 5 5 0.0092156403754289 335, 348, 351, 847, 1559 GO:0051961 BP e negative regulation of nervous system development 5/100 134/19669 0.0006107831827769 6 5 0.0092156403754289 3553, 3569, 4851, 5663, 6696 GO:0019438 BP e aromatic compound biosynthetic process 14/100 1017/19669 0.0006200464181592 4 14 0.0093462432668662 581, 1719, 1737, 2180, 2194, 2876, 4199, 4831, 4851, 4860, 5465, 5468, 6622, 9971 GO:0061912 BP e selective autophagy 3/100 33/19669 0.0006227520479935 6 3 0.0093503941645073 5071, 9474, 81631 GO:0010922 BP e positive regulation of phosphatase activity 3/100 33/19669 0.0006227520479935 9 3 0.0093503941645073 3458, 9104, 11035 GO:0055006 BP e cardiac cell development 3/100 33/19669 0.0006227520479935 4 3 0.0093503941645073 4851, 7422, 9474 GO:0046320 BP e regulation of fatty acid oxidation 3/100 33/19669 0.0006227520479935 7 3 0.0093503941645073 5166, 5465, 5468 GO:0051384 BP e response to glucocorticoid 5/100 135/19669 0.0006317475076265 7 5 0.0094762126143976 383, 1244, 3146, 3569, 9370 GO:0035966 BP e response to topologically incorrect protein 4/100 77/19669 0.0006405077554644 4 4 0.0095982613014584 581, 2081, 3309, 5071 GO:0032970 BP e regulation of actin filament-based process 8/100 374/19669 0.0006445860342998 4 8 0.0096499796380108 335, 1440, 2934, 5071, 5580, 10096, 50507, 136319 GO:0071901 BP e negative regulation of protein serine/threonine kinase activity 5/100 136/19669 0.0006532468952778 11 5 0.0097701357806861 183, 348, 3553, 5580, 9370 GO:0042509 BP e regulation of tyrosine phosphorylation of STAT protein 4/100 78/19669 0.0006725176206319 10 4 0.0100388420771341 3440, 3458, 3479, 3569 GO:2000117 BP e negative regulation of cysteine-type endopeptidase activity 4/100 78/19669 0.0006725176206319 11 4 0.0100388420771341 2876, 4318, 6622, 7422 GO:0090276 BP e regulation of peptide hormone secretion 6/100 208/19669 0.0006795248188579 9 6 0.0100993374079499 2243, 3458, 3553, 3569, 5071, 9971 GO:0045601 BP e regulation of endothelial cell differentiation 3/100 34/19669 0.0006805076603017 6 3 0.0100993374079499 3553, 4851, 7422 GO:0001885 BP e endothelial cell development 3/100 34/19669 0.0006805076603017 5 3 0.0100993374079499 2194, 2876, 2947 GO:0031663 BP e lipopolysaccharide-mediated signaling pathway 3/100 34/19669 0.0006805076603017 6 3 0.0100993374079499 3553, 3654, 6347 GO:0010543 BP e regulation of platelet activation 3/100 34/19669 0.0006805076603017 5 3 0.0100993374079499 348, 4846, 5580 GO:0032692 BP e negative regulation of interleukin-1 production 3/100 34/19669 0.0006805076603017 8 3 0.0100993374079499 335, 3479, 9971 GO:1901362 BP e organic cyclic compound biosynthetic process 15/100 1152/19669 0.0006961391234086 4 15 0.0103213690840653 335, 581, 1719, 1737, 2180, 2194, 2876, 4199, 4831, 4851, 4860, 5465, 5468, 6622, 9971 GO:0048845 BP e venous blood vessel morphogenesis 2/100 8/19669 0.000702406087053 5 2 0.0103247656922125 4851, 7422 GO:1902510 BP e regulation of apoptotic DNA fragmentation 2/100 8/19669 0.000702406087053 8 2 0.0103247656922125 581, 3569 GO:0019682 BP e glyceraldehyde-3-phosphate metabolic process 2/100 8/19669 0.000702406087053 5 2 0.0103247656922125 229, 6888 GO:0002887 BP e negative regulation of myeloid leukocyte mediated immunity 2/100 8/19669 0.000702406087053 7 2 0.0103247656922125 3162, 729230 GO:0032071 BP e regulation of endodeoxyribonuclease activity 2/100 8/19669 0.000702406087053 8 2 0.0103247656922125 3146, 5580 GO:1904796 BP e regulation of core promoter binding 2/100 8/19669 0.000702406087053 6 2 0.0103247656922125 3458, 5663 GO:0060982 BP e coronary artery morphogenesis 2/100 8/19669 0.000702406087053 6 2 0.0103247656922125 4851, 7422 GO:0000423 BP e mitophagy 2/100 8/19669 0.000702406087053 8 2 0.0103247656922125 5071, 81631 GO:0034351 BP e negative regulation of glial cell apoptotic process 2/100 8/19669 0.000702406087053 8 2 0.0103247656922125 5580, 6347 GO:0030324 BP e lung development 4/100 79/19669 0.0007056447512223 4 4 0.0103624739707176 383, 3146, 4851, 7422 GO:0044260 BP e cellular macromolecule metabolic process 38/100 4502/19669 0.0007171320853745 4 38 0.0105211275442467 60, 213, 335, 348, 351, 847, 1356, 1737, 2081, 2243, 2876, 2934, 3146, 3309, 3479, 3569, 3654, 4137, 4217, 4313, 4780, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 5836, 6347, 6622, 6696, 7276, 9474, 9971, 11035, 23476, 83667 GO:0030595 BP e leukocyte chemotaxis 5/100 139/19669 0.0007210426885935 6 5 0.0105583701022411 3146, 3569, 3627, 6347, 729230 GO:0050921 BP e positive regulation of chemotaxis 5/100 139/19669 0.0007210426885935 6 5 0.0105583701022411 3146, 3569, 3627, 7422, 729230 GO:1902003 BP e regulation of amyloid-beta formation 3/100 35/19669 0.0007415698438827 7 3 0.0108280454434113 348, 3458, 3479 GO:1904646 BP e cellular response to amyloid-beta 3/100 35/19669 0.0007415698438827 7 3 0.0108280454434113 351, 3479, 5663 GO:1905898 BP e positive regulation of response to endoplasmic reticulum stress 3/100 35/19669 0.0007415698438827 7 3 0.0108280454434113 581, 2081, 4780 GO:0006720 BP e isoprenoid metabolic process 5/100 140/19669 0.000744769816529 5 5 0.0108644620629213 335, 348, 1559, 1571, 7276 GO:0099601 BP e regulation of neurotransmitter receptor activity 4/100 81/19669 0.0007753373893639 7 4 0.0112996613847639 351, 3458, 6347, 729230 GO:0030030 BP e cell projection organization 12/100 805/19669 0.0007852882451654 4 12 0.0114338562848594 60, 335, 348, 351, 1719, 2934, 3146, 3569, 4137, 4851, 5663, 10096 GO:0032892 BP e positive regulation of organic acid transport 3/100 36/19669 0.0008060128105265 8 3 0.0116798368661639 2180, 3553, 5663 GO:0042157 BP e lipoprotein metabolic process 3/100 36/19669 0.0008060128105265 5 3 0.0116798368661639 335, 348, 5465 GO:0090207 BP e regulation of triglyceride metabolic process 3/100 36/19669 0.0008060128105265 6 3 0.0116798368661639 335, 348, 9104 GO:0061564 BP e axon development 3/100 36/19669 0.0008060128105265 7 3 0.0116798368661639 335, 1719, 4137 GO:0000096 BP e sulfur amino acid metabolic process 3/100 36/19669 0.0008060128105265 4 3 0.0116798368661639 4143, 4524, 50507 GO:1903050 BP e regulation of proteolysis involved in cellular protein catabolic process 6/100 215/19669 0.0008074948944508 8 6 0.0116798368661639 348, 2876, 4780, 5071, 5663, 9104 GO:0002699 BP e positive regulation of immune effector process 6/100 215/19669 0.0008074948944508 5 6 0.0116798368661639 383, 3162, 3458, 3553, 3569, 729230 GO:0006767 BP e water-soluble vitamin metabolic process 4/100 82/19669 0.0008119462528108 4 4 0.0117331951462519 1719, 4524, 5091, 9104 GO:0045580 BP e regulation of T cell differentiation 5/100 144/19669 0.0008455582636722 8 5 0.0122074499792837 3146, 3440, 3458, 4860, 729230 GO:0010822 BP e positive regulation of mitochondrion organization 4/100 83/19669 0.0008497590847951 7 4 0.0122451238904463 581, 3064, 4318, 5071 GO:0018958 BP e phenol-containing compound metabolic process 4/100 83/19669 0.0008497590847951 4 4 0.0122451238904463 1571, 5071, 6622, 136319 GO:0009416 BP e response to light stimulus 7/100 300/19669 0.0008548397512487 4 7 0.0123068136311671 351, 581, 847, 2876, 4313, 4318, 5580 GO:1903900 BP e regulation of viral life cycle 5/100 145/19669 0.000872270341655 5 5 0.0124763135221618 2934, 3440, 4851, 5091, 5465 GO:0055088 BP e lipid homeostasis 5/100 145/19669 0.000872270341655 5 5 0.0124763135221618 335, 348, 5468, 9971, 83667 GO:0090049 BP e regulation of cell migration involved in sprouting angiogenesis 3/100 37/19669 0.0008739094202008 10 3 0.0124763135221618 3162, 4851, 7422 GO:0071398 BP e cellular response to fatty acid 3/100 37/19669 0.0008739094202008 6 3 0.0124763135221618 4831, 5166, 9971 GO:0071276 BP e cellular response to cadmium ion 3/100 37/19669 0.0008739094202008 6 3 0.0124763135221618 2934, 3162, 4318 GO:0046326 BP e positive regulation of glucose import 3/100 37/19669 0.0008739094202008 10 3 0.0124763135221618 3479, 4780, 9370 GO:0045776 BP e negative regulation of blood pressure 3/100 37/19669 0.0008739094202008 4 3 0.0124763135221618 4846, 5465, 9370 GO:0006801 BP e superoxide metabolic process 3/100 37/19669 0.0008739094202008 4 3 0.0124763135221618 4846, 6649, 50507 GO:2000403 BP e positive regulation of lymphocyte migration 3/100 37/19669 0.0008739094202008 10 3 0.0124763135221618 351, 3627, 729230 GO:0032388 BP e positive regulation of intracellular transport 6/100 219/19669 0.0008885453129915 6 6 0.0126622886934458 302, 3458, 3553, 5071, 5580, 5663 GO:0046330 BP e positive regulation of JNK cascade 4/100 84/19669 0.0008887976097343 10 4 0.0126622886934458 351, 3146, 3553, 4217 GO:0090647 BP e modulation of age-related behavioral decline 2/100 9/19669 0.000900100313881 3 2 0.0126622886934458 351, 5663 GO:0051006 BP e positive regulation of lipoprotein lipase activity 2/100 9/19669 0.000900100313881 8 2 0.0126622886934458 335, 350 GO:2000425 BP e regulation of apoptotic cell clearance 2/100 9/19669 0.000900100313881 7 2 0.0126622886934458 3146, 6347 GO:1904385 BP e cellular response to angiotensin 2/100 9/19669 0.000900100313881 8 2 0.0126622886934458 4780, 5580 GO:1900122 BP e positive regulation of receptor binding 2/100 9/19669 0.000900100313881 6 2 0.0126622886934458 302, 4318 GO:1903599 BP e positive regulation of autophagy of mitochondrion 2/100 9/19669 0.000900100313881 8 2 0.0126622886934458 3064, 5071 GO:1903589 BP e positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 2/100 9/19669 0.000900100313881 8 2 0.0126622886934458 3162, 7422 GO:0034384 BP e high-density lipoprotein particle clearance 2/100 9/19669 0.000900100313881 3 2 0.0126622886934458 335, 348 GO:0034372 BP e very-low-density lipoprotein particle remodeling 2/100 9/19669 0.000900100313881 9 2 0.0126622886934458 335, 348 GO:0010623 BP e programmed cell death involved in cell development 2/100 9/19669 0.000900100313881 4 2 0.0126622886934458 581, 5591 GO:0010887 BP e negative regulation of cholesterol storage 2/100 9/19669 0.000900100313881 7 2 0.0126622886934458 5465, 5468 GO:0034371 BP e chylomicron remodeling 2/100 9/19669 0.000900100313881 9 2 0.0126622886934458 335, 348 GO:1905459 BP e regulation of vascular associated smooth muscle cell apoptotic process 2/100 9/19669 0.000900100313881 9 2 0.0126622886934458 3479, 5468 GO:0006527 BP e arginine catabolic process 2/100 9/19669 0.000900100313881 10 2 0.0126622886934458 383, 4846 GO:0009165 BP e nucleotide biosynthetic process 6/100 220/19669 0.0009097550736962 8 6 0.0127864206248264 1737, 2180, 2194, 4199, 4831, 4860 GO:0050810 BP e regulation of steroid biosynthetic process 4/100 85/19669 0.0009290835631819 7 4 0.0130224007626328 348, 2194, 3458, 9971 GO:1900182 BP e positive regulation of protein localization to nucleus 4/100 85/19669 0.0009290835631819 7 4 0.0130224007626328 3458, 5580, 5663, 83667 GO:0034644 BP e cellular response to UV 4/100 85/19669 0.0009290835631819 7 4 0.0130224007626328 581, 4313, 4318, 5580 GO:0009615 BP e response to virus 7/100 305/19669 0.0009412728501631 5 7 0.0131812458271251 581, 2023, 3440, 3458, 3569, 3627, 11035 GO:0006953 BP e acute-phase response 3/100 38/19669 0.0009453311951136 6 3 0.0132020391041728 1401, 3553, 3569 GO:1900744 BP e regulation of p38MAPK cascade 3/100 38/19669 0.0009453311951136 9 3 0.0132020391041728 3553, 4217, 7422 GO:0042307 BP e positive regulation of protein import into nucleus 3/100 38/19669 0.0009453311951136 11 3 0.0132020391041728 3458, 5580, 5663 GO:1902904 BP e negative regulation of supramolecular fiber organization 5/100 148/19669 0.0009561879373442 6 5 0.0133294677135216 348, 2934, 5071, 5580, 6622 GO:0010976 BP e positive regulation of neuron projection development 5/100 148/19669 0.0009561879373442 8 5 0.0133294677135216 348, 2896, 3309, 4780, 4831 GO:0009895 BP e negative regulation of catabolic process 7/100 306/19669 0.0009593586885495 5 7 0.0133615658070382 302, 3162, 3553, 5465, 5663, 6622, 9104 GO:0051952 BP e regulation of amine transport 4/100 86/19669 0.0009706386879075 7 4 0.0134942451733486 383, 5071, 5663, 6622 GO:0014013 BP e regulation of gliogenesis 4/100 86/19669 0.0009706386879075 7 4 0.0134942451733486 3553, 3569, 4851, 5468 GO:1901293 BP e nucleoside phosphate biosynthetic process 6/100 223/19669 0.0009757336835165 7 6 0.0135528351889173 1737, 2180, 2194, 4199, 4831, 4860 GO:0044271 BP e cellular nitrogen compound biosynthetic process 16/100 1324/19669 0.0010136721685226 4 16 0.014067100697532 383, 581, 1719, 1737, 2180, 2194, 2876, 4199, 4831, 4846, 4851, 4860, 5465, 5468, 6622, 9971 GO:1903364 BP e positive regulation of cellular protein catabolic process 5/100 150/19669 0.0010153760312569 8 5 0.0140780514604002 348, 4780, 5071, 5663, 9104 GO:0000422 BP e autophagy of mitochondrion 3/100 39/19669 0.0010203483337557 7 3 0.0140835523376696 5071, 9474, 81631 GO:0006730 BP e one-carbon metabolic process 3/100 39/19669 0.0010203483337557 3 3 0.0140835523376696 1719, 4143, 4524 GO:0061726 BP e mitochondrion disassembly 3/100 39/19669 0.0010203483337557 6 3 0.0140835523376696 5071, 9474, 81631 GO:0006984 BP e ER-nucleus signaling pathway 3/100 39/19669 0.0010203483337557 5 3 0.0140835523376696 3309, 4780, 6347 GO:2000279 BP e negative regulation of DNA biosynthetic process 3/100 39/19669 0.0010203483337557 8 3 0.0140835523376696 5468, 9104, 9370 GO:0030522 BP e intracellular receptor signaling pathway 5/100 151/19669 0.0010459707545224 5 5 0.0144242741147853 196, 3654, 5465, 5468, 9971 GO:0051222 BP e positive regulation of protein transport 7/100 311/19669 0.0010539429279184 9 7 0.0145212011286161 2243, 3458, 3479, 3553, 5580, 5663, 9971 GO:0014068 BP e positive regulation of phosphatidylinositol 3-kinase signaling 4/100 88/19669 0.0010576434350523 8 4 0.0145591524735732 183, 847, 1440, 3479 GO:0030258 BP e lipid modification 6/100 227/19669 0.001069367423066 5 6 0.0147073857381471 1571, 3030, 5468, 9370, 26061, 83667 GO:0007169 BP e transmembrane receptor protein tyrosine kinase signaling pathway 9/100 505/19669 0.0010858032554661 7 9 0.0149201000907362 60, 3479, 4313, 4318, 5166, 5327, 5663, 7422, 10096 GO:1904591 BP e positive regulation of protein import 3/100 40/19669 0.0010990297246131 10 3 0.0150859356102845 3458, 5580, 5663 GO:0009062 BP e fatty acid catabolic process 4/100 89/19669 0.001103136544055 8 4 0.0150859356102845 3030, 9370, 26061, 83667 GO:0034612 BP e response to tumor necrosis factor 5/100 153/19669 0.0011092081953752 5 5 0.0150859356102845 1244, 4217, 4780, 6347, 9370 GO:0043301 BP e negative regulation of leukocyte degranulation 2/100 10/19669 0.0011213976827917 10 2 0.0150859356102845 3162, 729230 GO:0051712 BP e positive regulation of killing of cells of other organism 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 383, 3458 GO:0070587 BP e regulation of cell-cell adhesion involved in gastrulation 2/100 10/19669 0.0011213976827917 6 2 0.0150859356102845 335, 9370 GO:0051593 BP e response to folic acid 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 2934, 4524 GO:2000048 BP e negative regulation of cell-cell adhesion mediated by cadherin 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 4851, 7422 GO:1902337 BP e regulation of apoptotic process involved in morphogenesis 2/100 10/19669 0.0011213976827917 8 2 0.0150859356102845 581, 4851 GO:0031340 BP e positive regulation of vesicle fusion 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 302, 6622 GO:0060977 BP e coronary vasculature morphogenesis 2/100 10/19669 0.0011213976827917 5 2 0.0150859356102845 4851, 7422 GO:0035767 BP e endothelial cell chemotaxis 2/100 10/19669 0.0011213976827917 8 2 0.0150859356102845 3146, 7422 GO:0097084 BP e vascular associated smooth muscle cell development 2/100 10/19669 0.0011213976827917 5 2 0.0150859356102845 4851, 7422 GO:0002725 BP e negative regulation of T cell cytokine production 2/100 10/19669 0.0011213976827917 9 2 0.0150859356102845 383, 3440 GO:0034350 BP e regulation of glial cell apoptotic process 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 5580, 6347 GO:0070327 BP e thyroid hormone transport 2/100 10/19669 0.0011213976827917 5 2 0.0150859356102845 1244, 7276 GO:0090494 BP e dopamine uptake 2/100 10/19669 0.0011213976827917 10 2 0.0150859356102845 5071, 6622 GO:0034115 BP e negative regulation of heterotypic cell-cell adhesion 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 335, 9370 GO:0061365 BP e positive regulation of triglyceride lipase activity 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 335, 350 GO:1904748 BP e regulation of apoptotic process involved in development 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 581, 4851 GO:0032966 BP e negative regulation of collagen biosynthetic process 2/100 10/19669 0.0011213976827917 6 2 0.0150859356102845 3569, 5468 GO:0032070 BP e regulation of deoxyribonuclease activity 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 3146, 5580 GO:1990535 BP e neuron projection maintenance 2/100 10/19669 0.0011213976827917 7 2 0.0150859356102845 351, 5663 GO:0090493 BP e catecholamine uptake 2/100 10/19669 0.0011213976827917 9 2 0.0150859356102845 5071, 6622 GO:0006996 BP e organelle organization 24/100 2428/19669 0.001135956583453 4 24 0.0152684470037921 60, 302, 348, 581, 847, 2896, 2934, 3064, 3146, 4137, 4524, 4846, 4851, 5071, 5591, 5663, 6347, 7846, 9131, 9474, 10096, 10383, 26061, 81631 GO:0001938 BP e positive regulation of endothelial cell proliferation 4/100 90/19669 0.0011499857902214 7 4 0.0154435264498324 383, 3146, 3162, 7422 GO:1902991 BP e regulation of amyloid precursor protein catabolic process 3/100 41/19669 0.0011814429598986 6 3 0.0158521422431041 348, 3458, 3479 GO:0051253 BP e negative regulation of RNA metabolic process 16/100 1344/19669 0.0011867105682787 7 16 0.0159089509109849 196, 2023, 3146, 3440, 3458, 3569, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971 GO:0030307 BP e positive regulation of cell growth 5/100 156/19669 0.0012093252989807 6 5 0.0161980124902641 3479, 4137, 5071, 7422, 136319 GO:0002831 BP e regulation of response to biotic stimulus 8/100 414/19669 0.0012403207859429 4 8 0.0165987277353587 348, 383, 2896, 3146, 3458, 5468, 5580, 5591 GO:0042100 BP e B cell proliferation 3/100 42/19669 0.0012676543492785 6 3 0.0169057196147288 581, 3440, 5580 GO:1990090 BP e cellular response to nerve growth factor stimulus 3/100 42/19669 0.0012676543492785 6 3 0.0169057196147288 351, 3309, 4137 GO:0009712 BP e catechol-containing compound metabolic process 3/100 42/19669 0.0012676543492785 5 3 0.0169057196147288 5071, 6622, 136319 GO:0006584 BP e catecholamine metabolic process 3/100 42/19669 0.0012676543492785 7 3 0.0169057196147288 5071, 6622, 136319 GO:0007611 BP e learning or memory 6/100 235/19669 0.0012772318722913 5 6 0.0170187000126089 348, 351, 3064, 4137, 5071, 5663 GO:0010639 BP e negative regulation of organelle organization 7/100 322/19669 0.0012878876088352 6 7 0.0171458393598396 2876, 2934, 3479, 4137, 5071, 5580, 6622 GO:0045926 BP e negative regulation of growth 6/100 236/19669 0.0013052438769318 4 6 0.0173618870060343 2023, 4851, 5465, 5468, 6696, 83667 GO:0034250 BP e positive regulation of cellular amide metabolic process 5/100 159/19669 0.0013159828167716 6 5 0.0174896161918101 3458, 3569, 4780, 5580, 5591 GO:0044106 BP e cellular amine metabolic process 4/100 94/19669 0.0013513783184998 5 4 0.0178317482672497 1244, 5071, 6622, 136319 GO:1901222 BP e regulation of NIK/NF-kappaB signaling 4/100 94/19669 0.0013513783184998 7 4 0.0178317482672497 351, 3146, 3553, 3654 GO:0061097 BP e regulation of protein tyrosine kinase activity 4/100 94/19669 0.0013513783184998 10 4 0.0178317482672497 183, 351, 5663, 50507 GO:0006367 BP e transcription initiation from RNA polymerase II promoter 5/100 160/19669 0.0013530332647038 9 5 0.0178317482672497 581, 4851, 5465, 5468, 9971 GO:2000273 BP e positive regulation of signaling receptor activity 3/100 43/19669 0.0013577289330539 7 3 0.0178317482672497 3458, 6347, 729230 GO:0090311 BP e regulation of protein deacetylation 3/100 43/19669 0.0013577289330539 8 3 0.0178317482672497 3458, 4137, 7422 GO:0021762 BP e substantia nigra development 3/100 43/19669 0.0013577289330539 4 3 0.0178317482672497 60, 1152, 3309 GO:0048538 BP e thymus development 3/100 43/19669 0.0013577289330539 5 3 0.0178317482672497 5591, 5663, 11035 GO:0045454 BP e cell redox homeostasis 3/100 43/19669 0.0013577289330539 5 3 0.0178317482672497 2876, 4780, 4846 GO:2000113 BP e negative regulation of cellular macromolecule biosynthetic process 17/100 1434/19669 0.0013648767923844 7 17 0.0178317482672497 196, 1719, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971, 83667 GO:0010269 BP e response to selenium ion 2/100 11/19669 0.0013660579081928 4 2 0.0178317482672497 383, 2876 GO:0034975 BP e protein folding in endoplasmic reticulum 2/100 11/19669 0.0013660579081928 3 2 0.0178317482672497 821, 3309 GO:0010713 BP e negative regulation of collagen metabolic process 2/100 11/19669 0.0013660579081928 5 2 0.0178317482672497 3569, 5468 GO:0034378 BP e chylomicron assembly 2/100 11/19669 0.0013660579081928 8 2 0.0178317482672497 335, 348 GO:2001269 BP e positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2/100 11/19669 0.0013660579081928 13 2 0.0178317482672497 581, 2934 GO:2000644 BP e regulation of receptor catabolic process 2/100 11/19669 0.0013660579081928 6 2 0.0178317482672497 302, 348 GO:0010917 BP e negative regulation of mitochondrial membrane potential 2/100 11/19669 0.0013660579081928 5 2 0.0178317482672497 581, 4137 GO:1901533 BP e negative regulation of hematopoietic progenitor cell differentiation 2/100 11/19669 0.0013660579081928 6 2 0.0178317482672497 4780, 4851 GO:2001171 BP e positive regulation of ATP biosynthetic process 2/100 11/19669 0.0013660579081928 11 2 0.0178317482672497 2023, 5465 GO:1900272 BP e negative regulation of long-term synaptic potentiation 2/100 11/19669 0.0013660579081928 9 2 0.0178317482672497 348, 351 GO:0071492 BP e cellular response to UV-A 2/100 11/19669 0.0013660579081928 8 2 0.0178317482672497 4313, 4318 GO:1904951 BP e positive regulation of establishment of protein localization 7/100 327/19669 0.0014068360362141 6 7 0.0183484801672333 2243, 3458, 3479, 3553, 5580, 5663, 9971 GO:0010558 BP e negative regulation of macromolecule biosynthetic process 17/100 1445/19669 0.0014111861807727 6 17 0.0183896319408062 196, 1719, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971, 83667 GO:1901137 BP e carbohydrate derivative biosynthetic process 8/100 424/19669 0.001442719991564 4 8 0.0187846536972685 1737, 2180, 2194, 3479, 3553, 4831, 5836, 6652 GO:0010828 BP e positive regulation of glucose transmembrane transport 3/100 44/19669 0.0014517304957866 9 3 0.0188065086954185 3479, 4780, 9370 GO:0045124 BP e regulation of bone resorption 3/100 44/19669 0.0014517304957866 6 3 0.0188065086954185 3569, 5166, 6696 GO:1990089 BP e response to nerve growth factor 3/100 44/19669 0.0014517304957866 5 3 0.0188065086954185 351, 3309, 4137 GO:0006094 BP e gluconeogenesis 3/100 44/19669 0.0014517304957866 7 3 0.0188065086954185 229, 2023, 5091 GO:0017144 BP e drug metabolic process 3/100 44/19669 0.0014517304957866 3 3 0.0188065086954185 1244, 1559, 1571 GO:0010677 BP e negative regulation of cellular carbohydrate metabolic process 3/100 44/19669 0.0014517304957866 7 3 0.0188065086954185 5071, 5465, 9370 GO:0001667 BP e ameboidal-type cell migration 5/100 163/19669 0.0014688129870427 5 5 0.0190118014050365 335, 2876, 3146, 4846, 7422 GO:1902679 BP e negative regulation of RNA biosynthetic process 15/100 1243/19669 0.0014977794593769 8 15 0.0193704419158076 196, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971 GO:0031341 BP e regulation of cell killing 4/100 97/19669 0.0015177245546469 4 4 0.0195954537718264 383, 3075, 3458, 11035 GO:0016525 BP e negative regulation of angiogenesis 4/100 97/19669 0.0015177245546469 8 4 0.0195954537718264 350, 3627, 5468, 729230 GO:1903202 BP e negative regulation of oxidative stress-induced cell death 3/100 45/19669 0.0015497215794198 8 3 0.0198947281821172 2876, 4780, 5071 GO:0006111 BP e regulation of gluconeogenesis 3/100 45/19669 0.0015497215794198 8 3 0.0198947281821172 5465, 9370, 83667 GO:0048146 BP e positive regulation of fibroblast proliferation 3/100 45/19669 0.0015497215794198 6 3 0.0198947281821172 183, 3479, 5591 GO:1903053 BP e regulation of extracellular matrix organization 3/100 45/19669 0.0015497215794198 5 3 0.0198947281821172 183, 3569, 4851 GO:0035384 BP e thioester biosynthetic process 3/100 45/19669 0.0015497215794198 5 3 0.0198947281821172 1737, 2180, 2194 GO:0071616 BP e acyl-CoA biosynthetic process 3/100 45/19669 0.0015497215794198 11 3 0.0198947281821172 1737, 2180, 2194 GO:0030833 BP e regulation of actin filament polymerization 5/100 165/19669 0.0015499531572682 10 5 0.0198947281821172 1440, 2934, 5580, 10096, 136319 GO:1902106 BP e negative regulation of leukocyte differentiation 4/100 98/19669 0.0015762031295093 7 4 0.0201979734913812 3146, 3440, 4831, 9370 GO:2000181 BP e negative regulation of blood vessel morphogenesis 4/100 98/19669 0.0015762031295093 7 4 0.0201979734913812 350, 3627, 5468, 729230 GO:0072522 BP e purine-containing compound biosynthetic process 5/100 166/19669 0.0015917384911001 5 5 0.0203631383026034 1737, 2180, 2194, 4831, 4860 GO:0046390 BP e ribose phosphate biosynthetic process 5/100 166/19669 0.0015917384911001 6 5 0.0203631383026034 1737, 2180, 2194, 4831, 5836 GO:0019693 BP e ribose phosphate metabolic process 7/100 335/19669 0.0016148612960984 5 7 0.020556422845633 229, 1737, 2023, 2180, 2194, 4831, 5836 GO:0071872 BP e cellular response to epinephrine stimulus 2/100 12/19669 0.0016338424951994 8 2 0.020556422845633 6622, 9370 GO:0009650 BP e UV protection 2/100 12/19669 0.0016338424951994 6 2 0.020556422845633 847, 2876 GO:0051340 BP e regulation of ligase activity 2/100 12/19669 0.0016338424951994 4 2 0.020556422845633 9104, 11035 GO:0018158 BP e protein oxidation 2/100 12/19669 0.0016338424951994 7 2 0.020556422845633 335, 2876 GO:0045837 BP e negative regulation of membrane potential 2/100 12/19669 0.0016338424951994 4 2 0.020556422845633 581, 4137 GO:0010642 BP e negative regulation of platelet-derived growth factor receptor signaling pathway 2/100 12/19669 0.0016338424951994 7 2 0.020556422845633 6622, 9370 GO:0042762 BP e regulation of sulfur metabolic process 2/100 12/19669 0.0016338424951994 5 2 0.020556422845633 4780, 5166 GO:0071941 BP e nitrogen cycle metabolic process 2/100 12/19669 0.0016338424951994 3 2 0.020556422845633 383, 1559 GO:0046500 BP e S-adenosylmethionine metabolic process 2/100 12/19669 0.0016338424951994 4 2 0.020556422845633 4143, 4524 GO:0009410 BP e response to xenobiotic stimulus 2/100 12/19669 0.0016338424951994 3 2 0.020556422845633 196, 2876 GO:0015872 BP e dopamine transport 2/100 12/19669 0.0016338424951994 9 2 0.020556422845633 5071, 6622 GO:1903332 BP e regulation of protein folding 2/100 12/19669 0.0016338424951994 4 2 0.020556422845633 2896, 3309 GO:0033700 BP e phospholipid efflux 2/100 12/19669 0.0016338424951994 9 2 0.020556422845633 335, 348 GO:0006995 BP e cellular response to nitrogen starvation 2/100 12/19669 0.0016338424951994 7 2 0.020556422845633 9474, 81631 GO:0043562 BP e cellular response to nitrogen levels 2/100 12/19669 0.0016338424951994 6 2 0.020556422845633 9474, 81631 GO:0050667 BP e homocysteine metabolic process 2/100 12/19669 0.0016338424951994 8 2 0.020556422845633 4524, 50507 GO:0010988 BP e regulation of low-density lipoprotein particle clearance 2/100 12/19669 0.0016338424951994 5 2 0.020556422845633 302, 9971 GO:0019627 BP e urea metabolic process 2/100 12/19669 0.0016338424951994 5 2 0.020556422845633 383, 1559 GO:0009308 BP e amine metabolic process 4/100 99/19669 0.0016362324877128 4 4 0.020556422845633 1244, 5071, 6622, 136319 GO:1901343 BP e negative regulation of vasculature development 4/100 99/19669 0.0016362324877128 6 4 0.020556422845633 350, 3627, 5468, 729230 GO:0045639 BP e positive regulation of myeloid cell differentiation 4/100 99/19669 0.0016362324877128 7 4 0.020556422845633 1440, 3146, 3458, 5591 GO:0031638 BP e zymogen activation 3/100 46/19669 0.0016517634968864 7 3 0.0207346168165433 350, 2243, 5327 GO:0046634 BP e regulation of alpha-beta T cell activation 4/100 100/19669 0.0016978340889043 8 4 0.0212782301532887 3146, 3458, 4860, 729230 GO:1903707 BP e negative regulation of hemopoiesis 4/100 100/19669 0.0016978340889043 6 4 0.0212782301532887 3146, 3440, 4831, 9370 GO:0042742 BP e defense response to bacterium 6/100 249/19669 0.001713878276087 6 6 0.021461828046363 1401, 2243, 3569, 3934, 5580, 9971 GO:0016485 BP e protein processing 5/100 169/19669 0.0017220726812844 6 5 0.0215469094024122 350, 1510, 2243, 5327, 5663 GO:0002673 BP e regulation of acute inflammatory response 3/100 47/19669 0.0017579163437394 7 3 0.0219240944328608 3553, 3569, 5468 GO:0010718 BP e positive regulation of epithelial to mesenchymal transition 3/100 47/19669 0.0017579163437394 6 3 0.0219240944328608 3553, 3569, 4851 GO:2000351 BP e regulation of endothelial cell apoptotic process 3/100 47/19669 0.0017579163437394 8 3 0.0219240944328608 2243, 4780, 6347 GO:0035722 BP e interleukin-12-mediated signaling pathway 3/100 47/19669 0.0017579163437394 7 3 0.0219240944328608 302, 3458, 6888 GO:0043200 BP e response to amino acid 4/100 101/19669 0.0017610293479096 5 4 0.021927379987322 383, 4313, 4524, 83667 GO:0002224 BP e toll-like receptor signaling pathway 4/100 101/19669 0.0017610293479096 6 4 0.021927379987322 2243, 3146, 3654, 9971 GO:0031327 BP e negative regulation of cellular biosynthetic process 17/100 1501/19669 0.0017674567117043 6 17 0.0219896190728616 196, 1719, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971, 83667 GO:0033157 BP e regulation of intracellular protein transport 6/100 251/19669 0.0017844999837538 9 6 0.0221837275847918 3458, 3553, 5071, 5580, 5663, 9370 GO:0018130 BP e heterocycle biosynthetic process 13/100 1011/19669 0.0018133179611132 4 13 0.0225237800012374 581, 1719, 1737, 2180, 2194, 2876, 4199, 4831, 4851, 4860, 5465, 5468, 9971 GO:0045637 BP e regulation of myeloid cell differentiation 6/100 253/19669 0.0018573115511032 6 6 0.0230516328802253 1440, 3146, 3458, 4831, 5591, 9370 GO:0042149 BP e cellular response to glucose starvation 3/100 48/19669 0.0018682390132759 7 3 0.023168572453116 3309, 4780, 83667 GO:0046822 BP e regulation of nucleocytoplasmic transport 4/100 103/19669 0.0018922862526429 6 4 0.0234478948697058 3458, 3553, 5580, 5663 GO:0034380 BP e high-density lipoprotein particle assembly 2/100 13/19669 0.0019245147277365 8 2 0.0236190443858571 335, 348 GO:0034370 BP e triglyceride-rich lipoprotein particle remodeling 2/100 13/19669 0.0019245147277365 8 2 0.0236190443858571 335, 348 GO:1990776 BP e response to angiotensin 2/100 13/19669 0.0019245147277365 7 2 0.0236190443858571 4780, 5580 GO:0150079 BP e negative regulation of neuroinflammatory response 2/100 13/19669 0.0019245147277365 8 2 0.0236190443858571 2896, 3479 GO:0044090 BP e positive regulation of vacuole organization 2/100 13/19669 0.0019245147277365 7 2 0.0236190443858571 302, 2896 GO:1900103 BP e positive regulation of endoplasmic reticulum unfolded protein response 2/100 13/19669 0.0019245147277365 8 2 0.0236190443858571 581, 2081 GO:0051589 BP e negative regulation of neurotransmitter transport 2/100 13/19669 0.0019245147277365 6 2 0.0236190443858571 5071, 6622 GO:0038183 BP e bile acid signaling pathway 2/100 13/19669 0.0019245147277365 5 2 0.0236190443858571 1244, 9971 GO:2001140 BP e positive regulation of phospholipid transport 2/100 13/19669 0.0019245147277365 9 2 0.0236190443858571 335, 348 GO:0019430 BP e removal of superoxide radicals 2/100 13/19669 0.0019245147277365 5 2 0.0236190443858571 4846, 6649 GO:0010818 BP e T cell chemotaxis 2/100 13/19669 0.0019245147277365 9 2 0.0236190443858571 3627, 729230 GO:0044793 BP e negative regulation by host of viral process 2/100 13/19669 0.0019245147277365 6 2 0.0236190443858571 1401, 5071 GO:0046916 BP e cellular transition metal ion homeostasis 4/100 104/19669 0.0019603904740361 9 4 0.0240019167823522 351, 1356, 3162, 3934 GO:0061387 BP e regulation of extent of cell growth 4/100 104/19669 0.0019603904740361 6 4 0.0240019167823522 348, 4137, 6696, 7422 GO:0002285 BP e lymphocyte activation involved in immune response 4/100 104/19669 0.0019603904740361 5 4 0.0240019167823522 3146, 3440, 3569, 5663 GO:0050918 BP e positive chemotaxis 3/100 49/19669 0.0019827892071211 4 3 0.0241991482137936 3146, 3627, 7422 GO:0045661 BP e regulation of myoblast differentiation 3/100 49/19669 0.0019827892071211 5 3 0.0241991482137936 3627, 4217, 4851 GO:0048247 BP e lymphocyte chemotaxis 3/100 49/19669 0.0019827892071211 8 3 0.0241991482137936 3627, 6347, 729230 GO:0044088 BP e regulation of vacuole organization 3/100 49/19669 0.0019827892071211 6 3 0.0241991482137936 302, 2023, 2896 GO:0032386 BP e regulation of intracellular transport 7/100 348/19669 0.0020032747755768 5 7 0.0244297930238734 302, 3458, 3553, 5071, 5580, 5663, 9370 GO:0030217 BP e T cell differentiation 4/100 105/19669 0.002030173499188 7 4 0.0247382186480639 3146, 3569, 5591, 11035 GO:0030198 BP e extracellular matrix organization 7/100 349/19669 0.0020359092378667 5 7 0.0247884835211784 351, 2243, 4313, 4318, 6696, 7276, 7450 GO:0043062 BP e extracellular structure organization 7/100 350/19669 0.0020689547261506 4 7 0.025170919553722 351, 2243, 4313, 4318, 6696, 7276, 7450 GO:0043412 BP e macromolecule modification 28/100 3091/19669 0.0020862881629077 4 28 0.0253617494685225 60, 213, 335, 348, 351, 1356, 1737, 2081, 2243, 2876, 3569, 3654, 4137, 4217, 4780, 4831, 5071, 5166, 5327, 5580, 5591, 5663, 6347, 6696, 9474, 9971, 11035, 23476 GO:0045912 BP e negative regulation of carbohydrate metabolic process 3/100 50/19669 0.0021016234494815 6 3 0.0255280070146174 5071, 5465, 9370 GO:0050796 BP e regulation of insulin secretion 5/100 177/19669 0.0021078684919198 10 5 0.0255836719957784 3458, 3553, 3569, 5071, 9971 GO:0045229 BP e external encapsulating structure organization 7/100 352/19669 0.0021362927764213 4 7 0.0259082315438333 351, 2243, 4313, 4318, 6696, 7276, 7450 GO:1901361 BP e organic cyclic compound catabolic process 8/100 452/19669 0.0021520472269903 4 8 0.0260787455302213 348, 2081, 2876, 3146, 3162, 4780, 4860, 6696 GO:0048511 BP e rhythmic process 6/100 261/19669 0.0021713346930966 1 6 0.0262917709887947 196, 3309, 5465, 5468, 5591, 9370 GO:2000677 BP e regulation of transcription regulatory region DNA binding 3/100 51/19669 0.0022247970992282 5 3 0.0268436105418771 3458, 3479, 5663 GO:0046850 BP e regulation of bone remodeling 3/100 51/19669 0.0022247970992282 5 3 0.0268436105418771 3569, 5166, 6696 GO:0030002 BP e cellular anion homeostasis 2/100 14/19669 0.0022378396572598 7 2 0.0268436105418771 1152, 1244 GO:0034393 BP e positive regulation of smooth muscle cell apoptotic process 2/100 14/19669 0.0022378396572598 9 2 0.0268436105418771 3458, 5468 GO:0044794 BP e positive regulation by host of viral process 2/100 14/19669 0.0022378396572598 6 2 0.0268436105418771 348, 5091 GO:0070141 BP e response to UV-A 2/100 14/19669 0.0022378396572598 6 2 0.0268436105418771 4313, 4318 GO:0051937 BP e catecholamine transport 2/100 14/19669 0.0022378396572598 8 2 0.0268436105418771 5071, 6622 GO:0150078 BP e positive regulation of neuroinflammatory response 2/100 14/19669 0.0022378396572598 8 2 0.0268436105418771 3553, 3569 GO:1903727 BP e positive regulation of phospholipid metabolic process 2/100 14/19669 0.0022378396572598 8 2 0.0268436105418771 5580, 9971 GO:1903894 BP e regulation of IRE1-mediated unfolded protein response 2/100 14/19669 0.0022378396572598 8 2 0.0268436105418771 581, 3309 GO:0010889 BP e regulation of sequestering of triglyceride 2/100 14/19669 0.0022378396572598 5 2 0.0268436105418771 5465, 5468 GO:1903729 BP e regulation of plasma membrane organization 2/100 14/19669 0.0022378396572598 5 2 0.0268436105418771 2934, 5580 GO:0007033 BP e vacuole organization 4/100 108/19669 0.0022498065170986 5 4 0.0269661388614863 2896, 5663, 9474, 81631 GO:0006898 BP e receptor-mediated endocytosis 5/100 180/19669 0.0022676435710776 6 5 0.027158781757887 213, 335, 348, 821, 6622 GO:0022414 BP e reproductive process 16/100 1385/19669 0.0022826639541091 1 16 0.0273174169935769 351, 383, 581, 1244, 3309, 3553, 4313, 4318, 4851, 5468, 5591, 6652, 6696, 7422, 9104, 10096 GO:0030308 BP e negative regulation of cell growth 5/100 181/19669 0.0023228120818897 6 5 0.027754718897735 2023, 5465, 5468, 6696, 83667 GO:0008064 BP e regulation of actin polymerization or depolymerization 5/100 181/19669 0.0023228120818897 9 5 0.027754718897735 1440, 2934, 5580, 10096, 136319 GO:0002886 BP e regulation of myeloid leukocyte mediated immunity 3/100 52/19669 0.0023523643621324 6 3 0.0280642539017202 383, 3162, 729230 GO:0045428 BP e regulation of nitric oxide biosynthetic process 3/100 52/19669 0.0023523643621324 7 3 0.0280642539017202 3458, 3553, 9104 GO:0030832 BP e regulation of actin filament length 5/100 182/19669 0.0023789523259351 8 5 0.0282937220217485 1440, 2934, 5580, 10096, 136319 GO:0043123 BP e positive regulation of I-kappaB kinase/NF-kappaB signaling 5/100 182/19669 0.0023789523259351 8 5 0.0282937220217485 3162, 3654, 5071, 9370, 23476 GO:0050792 BP e regulation of viral process 5/100 182/19669 0.0023789523259351 4 5 0.0282937220217485 2934, 3440, 4851, 5091, 5465 GO:0061136 BP e regulation of proteasomal protein catabolic process 5/100 182/19669 0.0023789523259351 9 5 0.0282937220217485 348, 2876, 4780, 5071, 5663 GO:0048646 BP e anatomical structure formation involved in morphogenesis 10/100 680/19669 0.0024101292334436 2 10 0.0286423852530486 302, 2876, 3162, 4313, 4524, 4851, 5591, 5663, 6347, 7422 GO:0015908 BP e fatty acid transport 4/100 111/19669 0.0024853060395656 8 4 0.0295130092198425 348, 2180, 5468, 5663 GO:0016052 BP e carbohydrate catabolic process 4/100 112/19669 0.0025674290199722 4 4 0.0301886121710102 229, 2023, 5836, 6652 GO:0071482 BP e cellular response to light stimulus 4/100 112/19669 0.0025674290199722 6 4 0.0301886121710102 581, 4313, 4318, 5580 GO:0090287 BP e regulation of cellular response to growth factor stimulus 6/100 270/19669 0.0025708717270714 4 6 0.0301886121710102 183, 3309, 3553, 4851, 5465, 5468 GO:0007346 BP e regulation of mitotic cell cycle 9/100 573/19669 0.0025725980769969 5 9 0.0301886121710102 351, 581, 3479, 3553, 5591, 6347, 7846, 10383, 23476 GO:0043403 BP e skeletal muscle tissue regeneration 2/100 15/19669 0.0025735840915117 5 2 0.0301886121710102 2876, 136319 GO:0055064 BP e chloride ion homeostasis 2/100 15/19669 0.0025735840915117 8 2 0.0301886121710102 1152, 1244 GO:0051770 BP e positive regulation of nitric-oxide synthase biosynthetic process 2/100 15/19669 0.0025735840915117 7 2 0.0301886121710102 3458, 6347 GO:0006000 BP e fructose metabolic process 2/100 15/19669 0.0025735840915117 6 2 0.0301886121710102 229, 6652 GO:0055083 BP e monovalent inorganic anion homeostasis 2/100 15/19669 0.0025735840915117 7 2 0.0301886121710102 1152, 1244 GO:0046321 BP e positive regulation of fatty acid oxidation 2/100 15/19669 0.0025735840915117 8 2 0.0301886121710102 5465, 5468 GO:1901201 BP e regulation of extracellular matrix assembly 2/100 15/19669 0.0025735840915117 6 2 0.0301886121710102 183, 4851 GO:0003184 BP e pulmonary valve morphogenesis 2/100 15/19669 0.0025735840915117 4 2 0.0301886121710102 4846, 4851 GO:0060252 BP e positive regulation of glial cell proliferation 2/100 15/19669 0.0025735840915117 9 2 0.0301886121710102 3553, 3569 GO:0060561 BP e apoptotic process involved in morphogenesis 2/100 15/19669 0.0025735840915117 6 2 0.0301886121710102 581, 4851 GO:0071871 BP e response to epinephrine 2/100 15/19669 0.0025735840915117 7 2 0.0301886121710102 6622, 9370 GO:0002827 BP e positive regulation of T-helper 1 type immune response 2/100 15/19669 0.0025735840915117 8 2 0.0301886121710102 3553, 729230 GO:0050821 BP e protein stabilization 5/100 186/19669 0.0026134309319296 4 5 0.0306326748228469 335, 2896, 3479, 5071, 5580 GO:0006520 BP e cellular amino acid metabolic process 6/100 271/19669 0.002618457738573 6 6 0.0306500838546563 383, 1719, 4143, 4524, 4846, 50507 GO:0080164 BP e regulation of nitric oxide metabolic process 3/100 54/19669 0.0026208908611259 6 3 0.0306500838546563 3458, 3553, 9104 GO:0035065 BP e regulation of histone acetylation 3/100 54/19669 0.0026208908611259 10 3 0.0306500838546563 3553, 6622, 9474 GO:0051224 BP e negative regulation of protein transport 4/100 113/19669 0.0026513980514332 9 4 0.0309833075258597 348, 3553, 5071, 9370 GO:1901565 BP e organonitrogen compound catabolic process 11/100 810/19669 0.0027209427966408 4 11 0.0317718586041752 302, 348, 383, 2876, 3162, 3309, 4143, 4780, 4846, 4860, 5071 GO:0034341 BP e response to interferon-gamma 4/100 114/19669 0.0027372337032148 5 4 0.0319378519275791 2934, 6347, 6622, 10096 GO:0048844 BP e artery morphogenesis 3/100 55/19669 0.0027619528558033 5 3 0.0320803429817455 348, 4851, 7422 GO:0050805 BP e negative regulation of synaptic transmission 3/100 55/19669 0.0027619528558033 7 3 0.0320803429817455 3553, 5071, 9370 GO:0090303 BP e positive regulation of wound healing 3/100 55/19669 0.0027619528558033 7 3 0.0320803429817455 350, 3146, 4780 GO:0055021 BP e regulation of cardiac muscle tissue growth 3/100 55/19669 0.0027619528558033 7 3 0.0320803429817455 3479, 4851, 5465 GO:0000045 BP e autophagosome assembly 3/100 55/19669 0.0027619528558033 7 3 0.0320803429817455 5663, 9474, 81631 GO:0046324 BP e regulation of glucose import 3/100 55/19669 0.0027619528558033 9 3 0.0320803429817455 3479, 4780, 9370 GO:0007204 BP e positive regulation of cytosolic calcium ion concentration 6/100 275/19669 0.0028154547751215 11 6 0.0326771108515242 581, 3064, 3146, 3627, 6622, 729230 GO:0045667 BP e regulation of osteoblast differentiation 4/100 115/19669 0.0028249564617386 5 4 0.0327380120076486 3479, 3569, 4851, 5468 GO:0032273 BP e positive regulation of protein polymerization 4/100 115/19669 0.0028249564617386 7 4 0.0327380120076486 1440, 2934, 4137, 10096 GO:0009612 BP e response to mechanical stimulus 5/100 190/19669 0.0028642592846182 3 5 0.0331682978802806 2934, 3553, 3627, 5468, 136319 GO:0050890 BP e cognition 6/100 276/19669 0.0028663961131106 4 6 0.0331682978802806 348, 351, 3064, 4137, 5071, 5663 GO:0090181 BP e regulation of cholesterol metabolic process 3/100 56/19669 0.0029076140045864 7 3 0.0333451886151137 348, 2194, 9971 GO:0032720 BP e negative regulation of tumor necrosis factor production 3/100 56/19669 0.0029076140045864 9 3 0.0333451886151137 3479, 9370, 9971 GO:0042306 BP e regulation of protein import into nucleus 3/100 56/19669 0.0029076140045864 10 3 0.0333451886151137 3458, 5580, 5663 GO:0006633 BP e fatty acid biosynthetic process 4/100 116/19669 0.0029145867278138 8 4 0.0333451886151137 1559, 1571, 2194, 2944 GO:0009888 BP e tissue development 9/100 584/19669 0.0029198179301076 3 9 0.0333451886151137 847, 2876, 2934, 3479, 4851, 5465, 6696, 7422, 136319 GO:1901654 BP e response to ketone 5/100 191/19669 0.0029295963568177 4 5 0.0333451886151137 196, 383, 1244, 5468, 6696 GO:0006525 BP e arginine metabolic process 2/100 16/19669 0.0029315165819524 9 2 0.0333451886151137 383, 4846 GO:1903541 BP e regulation of exosomal secretion 2/100 16/19669 0.0029315165819524 8 2 0.0333451886151137 3458, 5071 GO:0010885 BP e regulation of cholesterol storage 2/100 16/19669 0.0029315165819524 5 2 0.0333451886151137 5465, 5468 GO:0034116 BP e positive regulation of heterotypic cell-cell adhesion 2/100 16/19669 0.0029315165819524 7 2 0.0333451886151137 2243, 3553 GO:0035067 BP e negative regulation of histone acetylation 2/100 16/19669 0.0029315165819524 11 2 0.0333451886151137 6622, 9474 GO:0034162 BP e toll-like receptor 9 signaling pathway 2/100 16/19669 0.0029315165819524 7 2 0.0333451886151137 3654, 9971 GO:0006555 BP e methionine metabolic process 2/100 16/19669 0.0029315165819524 9 2 0.0333451886151137 4143, 4524 GO:0010819 BP e regulation of T cell chemotaxis 2/100 16/19669 0.0029315165819524 11 2 0.0333451886151137 3627, 729230 GO:0055089 BP e fatty acid homeostasis 2/100 16/19669 0.0029315165819524 6 2 0.0333451886151137 348, 9971 GO:1903587 BP e regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 2/100 16/19669 0.0029315165819524 7 2 0.0333451886151137 3162, 7422 GO:0008631 BP e intrinsic apoptotic signaling pathway in response to oxidative stress 2/100 16/19669 0.0029315165819524 7 2 0.0333451886151137 4217, 5580 GO:0033599 BP e regulation of mammary gland epithelial cell proliferation 2/100 16/19669 0.0029315165819524 6 2 0.0333451886151137 581, 2876 GO:0060055 BP e angiogenesis involved in wound healing 2/100 16/19669 0.0029315165819524 4 2 0.0333451886151137 2876, 7422 GO:0051709 BP e regulation of killing of cells of other organism 2/100 16/19669 0.0029315165819524 5 2 0.0333451886151137 383, 3458 GO:0060047 BP e heart contraction 2/100 16/19669 0.0029315165819524 5 2 0.0333451886151137 2876, 9474 GO:0051580 BP e regulation of neurotransmitter uptake 2/100 16/19669 0.0029315165819524 6 2 0.0333451886151137 5071, 6622 GO:0033151 BP e V(D)J recombination 2/100 16/19669 0.0029315165819524 10 2 0.0333451886151137 3146, 5591 GO:0034654 BP e nucleobase-containing compound biosynthetic process 12/100 942/19669 0.002951060145586 5 12 0.0335426998822519 581, 1737, 2180, 2194, 2876, 4199, 4831, 4851, 4860, 5465, 5468, 9971 GO:1901888 BP e regulation of cell junction assembly 5/100 192/19669 0.0029960055285347 5 5 0.0340033370827059 183, 351, 3553, 6622, 7422 GO:1903792 BP e negative regulation of anion transport 5/100 192/19669 0.0029960055285347 7 5 0.0340033370827059 348, 3553, 5071, 6622, 9370 GO:0002064 BP e epithelial cell development 4/100 117/19669 0.0030061448148216 4 4 0.0340932709654426 2194, 2876, 2947, 4851 GO:0048857 BP e neural nucleus development 3/100 57/19669 0.0030579229332411 3 3 0.0346294583830619 60, 1152, 3309 GO:0006165 BP e nucleoside diphosphate phosphorylation 3/100 57/19669 0.0030579229332411 8 3 0.0346294583830619 229, 2023, 4831 GO:0045934 BP e negative regulation of nucleobase-containing compound metabolic process 16/100 1451/19669 0.0030603090129279 6 16 0.0346309968448246 196, 2023, 3146, 3440, 3458, 3569, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9104, 9370, 9971 GO:0009749 BP e response to glucose 4/100 118/19669 0.0030996509462358 7 4 0.0350504247337024 2081, 4831, 9370, 83667 GO:2001235 BP e positive regulation of apoptotic signaling pathway 4/100 119/19669 0.0031951252534339 8 4 0.036103507819639 183, 581, 5580, 11035 GO:0006635 BP e fatty acid beta-oxidation 3/100 58/19669 0.0032129271870985 9 3 0.0361718722819652 3030, 9370, 83667 GO:1903556 BP e negative regulation of tumor necrosis factor superfamily cytokine production 3/100 58/19669 0.0032129271870985 8 3 0.0361718722819652 3479, 9370, 9971 GO:0032663 BP e regulation of interleukin-2 production 3/100 58/19669 0.0032129271870985 7 3 0.0361718722819652 3553, 9971, 729230 GO:1905037 BP e autophagosome organization 3/100 58/19669 0.0032129271870985 6 3 0.0361718722819652 5663, 9474, 81631 GO:0046939 BP e nucleotide phosphorylation 3/100 58/19669 0.0032129271870985 6 3 0.0361718722819652 229, 2023, 4831 GO:0006766 BP e vitamin metabolic process 4/100 120/19669 0.0032925877738057 3 4 0.0369829899020076 1719, 4524, 5091, 9104 GO:0007597 BP e blood coagulation, intrinsic pathway 2/100 17/19669 0.0033114074129283 6 2 0.0369829899020076 350, 7450 GO:1901550 BP e regulation of endothelial cell development 2/100 17/19669 0.0033114074129283 7 2 0.0369829899020076 3553, 7422 GO:1903140 BP e regulation of establishment of endothelial barrier 2/100 17/19669 0.0033114074129283 8 2 0.0369829899020076 3553, 7422 GO:2000811 BP e negative regulation of anoikis 2/100 17/19669 0.0033114074129283 8 2 0.0369829899020076 4851, 5166 GO:0002407 BP e dendritic cell chemotaxis 2/100 17/19669 0.0033114074129283 8 2 0.0369829899020076 3146, 729230 GO:0090190 BP e positive regulation of branching involved in ureteric bud morphogenesis 2/100 17/19669 0.0033114074129283 7 2 0.0369829899020076 183, 7422 GO:1900221 BP e regulation of amyloid-beta clearance 2/100 17/19669 0.0033114074129283 4 2 0.0369829899020076 348, 3458 GO:0043691 BP e reverse cholesterol transport 2/100 17/19669 0.0033114074129283 10 2 0.0369829899020076 335, 348 GO:0033194 BP e response to hydroperoxide 2/100 17/19669 0.0033114074129283 4 2 0.0369829899020076 2876, 5580 GO:0034374 BP e low-density lipoprotein particle remodeling 2/100 17/19669 0.0033114074129283 8 2 0.0369829899020076 183, 348 GO:0051054 BP e positive regulation of DNA metabolic process 5/100 197/19669 0.0033444848255425 7 5 0.0373253237600437 581, 3146, 3569, 5580, 5591 GO:1904589 BP e regulation of protein import 3/100 59/19669 0.0033726732428411 9 3 0.0375310493183843 3458, 5580, 5663 GO:0033866 BP e nucleoside bisphosphate biosynthetic process 3/100 59/19669 0.0033726732428411 8 3 0.0375310493183843 1737, 2180, 2194 GO:0034030 BP e ribonucleoside bisphosphate biosynthetic process 3/100 59/19669 0.0033726732428411 9 3 0.0375310493183843 1737, 2180, 2194 GO:0034033 BP e purine nucleoside bisphosphate biosynthetic process 3/100 59/19669 0.0033726732428411 9 3 0.0375310493183843 1737, 2180, 2194 GO:0061024 BP e membrane organization 10/100 715/19669 0.0034514105844307 4 10 0.0383794861953677 60, 302, 335, 348, 581, 2934, 5243, 5580, 10096, 26762 GO:0014066 BP e regulation of phosphatidylinositol 3-kinase signaling 4/100 122/19669 0.0034935571192141 7 4 0.0388201040178375 183, 847, 1440, 3479 GO:0043271 BP e negative regulation of ion transport 6/100 288/19669 0.0035330546584901 6 6 0.0391919426635607 348, 3553, 4318, 5071, 6622, 9370 GO:0046888 BP e negative regulation of hormone secretion 3/100 60/19669 0.0035372065210971 8 3 0.0391919426635607 3553, 5071, 9370 GO:1905330 BP e regulation of morphogenesis of an epithelium 3/100 60/19669 0.0035372065210971 5 3 0.0391919426635607 183, 3627, 7422 GO:0016239 BP e positive regulation of macroautophagy 3/100 60/19669 0.0035372065210971 8 3 0.0391919426635607 3064, 3162, 83667 GO:0009746 BP e response to hexose 4/100 123/19669 0.0035971035292897 6 4 0.0398269232487546 2081, 4831, 9370, 83667 GO:0030098 BP e lymphocyte differentiation 5/100 201/19669 0.0036435914794504 6 5 0.0403126332629343 3146, 3440, 3569, 5591, 11035 GO:0002526 BP e acute inflammatory response 3/100 61/19669 0.0037065713973481 5 3 0.0406137242507814 1401, 3553, 3569 GO:2000272 BP e negative regulation of signaling receptor activity 3/100 61/19669 0.0037065713973481 7 3 0.0406137242507814 5465, 5468, 5663 GO:0050709 BP e negative regulation of protein secretion 3/100 61/19669 0.0037065713973481 10 3 0.0406137242507814 348, 3553, 5071 GO:0032963 BP e collagen metabolic process 3/100 61/19669 0.0037065713973481 2 3 0.0406137242507814 383, 4313, 4318 GO:0015909 BP e long-chain fatty acid transport 3/100 61/19669 0.0037065713973481 9 3 0.0406137242507814 348, 2180, 5468 GO:1903978 BP e regulation of microglial cell activation 2/100 18/19669 0.0037130285913482 8 2 0.0406137242507814 2896, 3569 GO:0061050 BP e regulation of cell growth involved in cardiac muscle cell development 2/100 18/19669 0.0037130285913482 8 2 0.0406137242507814 3479, 5465 GO:0003203 BP e endocardial cushion morphogenesis 2/100 18/19669 0.0037130285913482 5 2 0.0406137242507814 4846, 4851 GO:0010984 BP e regulation of lipoprotein particle clearance 2/100 18/19669 0.0037130285913482 4 2 0.0406137242507814 302, 9971 GO:0030851 BP e granulocyte differentiation 2/100 18/19669 0.0037130285913482 6 2 0.0406137242507814 1440, 2194 GO:0098810 BP e neurotransmitter reuptake 2/100 18/19669 0.0037130285913482 6 2 0.0406137242507814 5071, 6622 GO:0070875 BP e positive regulation of glycogen metabolic process 2/100 18/19669 0.0037130285913482 9 2 0.0406137242507814 3146, 3479 GO:1902430 BP e negative regulation of amyloid-beta formation 2/100 18/19669 0.0037130285913482 8 2 0.0406137242507814 348, 3479 GO:0045618 BP e positive regulation of keratinocyte differentiation 2/100 18/19669 0.0037130285913482 8 2 0.0406137242507814 4831, 4851 GO:0046653 BP e tetrahydrofolate metabolic process 2/100 18/19669 0.0037130285913482 6 2 0.0406137242507814 1719, 4524 GO:2001169 BP e regulation of ATP biosynthetic process 2/100 18/19669 0.0037130285913482 10 2 0.0406137242507814 2023, 5465 GO:1903829 BP e positive regulation of cellular protein localization 6/100 292/19669 0.0037790499978735 6 6 0.0413065195080066 3458, 4137, 5071, 5580, 5663, 83667 GO:0071356 BP e cellular response to tumor necrosis factor 4/100 125/19669 0.0038104180213733 6 4 0.0415903073396709 1244, 4217, 4780, 6347 GO:0097529 BP e myeloid leukocyte migration 4/100 125/19669 0.0038104180213733 6 4 0.0415903073396709 3569, 3627, 6347, 729230 GO:1903201 BP e regulation of oxidative stress-induced cell death 3/100 62/19669 0.0038808112129693 7 3 0.0422687081157803 2876, 4780, 5071 GO:2000756 BP e regulation of peptidyl-lysine acetylation 3/100 62/19669 0.0038808112129693 9 3 0.0422687081157803 3553, 6622, 9474 GO:0060420 BP e regulation of heart growth 3/100 62/19669 0.0038808112129693 6 3 0.0422687081157803 3479, 4851, 5465 GO:1903038 BP e negative regulation of leukocyte cell-cell adhesion 4/100 126/19669 0.0039202250686474 7 4 0.0426075309367824 383, 3146, 3440, 5465 GO:0002221 BP e pattern recognition receptor signaling pathway 4/100 126/19669 0.0039202250686474 5 4 0.0426075309367824 2243, 3146, 3654, 9971 GO:0090101 BP e negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4/100 126/19669 0.0039202250686474 7 4 0.0426075309367824 3309, 4851, 5465, 5468 GO:0016042 BP e lipid catabolic process 6/100 295/19669 0.0039717403838966 4 6 0.0431369686013894 348, 3030, 6696, 9370, 26061, 83667 GO:0022402 BP e cell cycle process 12/100 978/19669 0.003990584836192 2 12 0.0433110723758786 581, 1719, 2081, 3064, 3458, 4851, 5243, 5591, 7846, 10096, 10383, 23476 GO:1903052 BP e positive regulation of proteolysis involved in cellular protein catabolic process 4/100 127/19669 0.0040321577811865 9 4 0.0437314364006072 4780, 5071, 5663, 9104 GO:0045824 BP e negative regulation of innate immune response 3/100 63/19669 0.0040599682874465 7 3 0.0440020506646498 383, 2896, 5468 GO:0006352 BP e DNA-templated transcription, initiation 5/100 207/19669 0.0041276287493737 8 5 0.0445142709753173 581, 4851, 5465, 5468, 9971 GO:2000757 BP e negative regulation of peptidyl-lysine acetylation 2/100 19/19669 0.004136153833314 10 2 0.0445142709753173 6622, 9474 GO:0046655 BP e folic acid metabolic process 2/100 19/19669 0.004136153833314 7 2 0.0445142709753173 1719, 4524 GO:1905517 BP e macrophage migration 2/100 19/19669 0.004136153833314 7 2 0.0445142709753173 6347, 729230 GO:0019373 BP e epoxygenase P450 pathway 2/100 19/19669 0.004136153833314 10 2 0.0445142709753173 1559, 1571 GO:0051769 BP e regulation of nitric-oxide synthase biosynthetic process 2/100 19/19669 0.004136153833314 6 2 0.0445142709753173 3458, 6347 GO:0042730 BP e fibrinolysis 2/100 19/19669 0.004136153833314 9 2 0.0445142709753173 2243, 5327 GO:0060965 BP e negative regulation of gene silencing by miRNA 2/100 19/19669 0.004136153833314 9 2 0.0445142709753173 3569, 5468 GO:0015844 BP e monoamine transport 2/100 19/19669 0.004136153833314 7 2 0.0445142709753173 5071, 6622 GO:0045123 BP e cellular extravasation 2/100 19/19669 0.004136153833314 6 2 0.0445142709753173 6347, 729230 GO:0035303 BP e regulation of dephosphorylation 5/100 208/19669 0.0042125574173959 7 5 0.0452416319984113 3064, 3458, 5580, 9104, 11035 GO:0140546 BP e defense response to symbiont 5/100 208/19669 0.0042125574173959 6 5 0.0452416319984113 3440, 3458, 3569, 3627, 11035 GO:0051607 BP e defense response to virus 5/100 208/19669 0.0042125574173959 7 5 0.0452416319984113 3440, 3458, 3569, 3627, 11035 GO:1900076 BP e regulation of cellular response to insulin stimulus 3/100 64/19669 0.0042440839296606 4 3 0.0454849942043719 3553, 5580, 9971 GO:0046635 BP e positive regulation of alpha-beta T cell activation 3/100 64/19669 0.0042440839296606 9 3 0.0454849942043719 3458, 4860, 729230 GO:0006879 BP e cellular iron ion homeostasis 3/100 64/19669 0.0042440839296606 10 3 0.0454849942043719 1356, 3162, 3934 GO:1900180 BP e regulation of protein localization to nucleus 4/100 130/19669 0.0043809014699216 6 4 0.0469186316089731 3458, 5580, 5663, 83667 GO:0045685 BP e regulation of glial cell differentiation 3/100 65/19669 0.0044331984485106 5 3 0.0474457052312785 3569, 4851, 5468 GO:0019932 BP e second-messenger-mediated signaling 5/100 211/19669 0.0044748385591445 6 5 0.0478580718729915 183, 196, 348, 4846, 729230 GO:0022604 BP e regulation of cell morphogenesis 6/100 303/19669 0.0045212251554023 5 6 0.0483205938483622 335, 2243, 5071, 5591, 6347, 7422 GO:0033141 BP e positive regulation of peptidyl-serine phosphorylation of STAT protein 2/100 20/19669 0.0045805585541132 11 2 0.0484789058185174 3440, 3458 GO:0090050 BP e positive regulation of cell migration involved in sprouting angiogenesis 2/100 20/19669 0.0045805585541132 11 2 0.0484789058185174 3162, 7422 GO:0046597 BP e negative regulation of viral entry into host cell 2/100 20/19669 0.0045805585541132 7 2 0.0484789058185174 2934, 3440 GO:0060149 BP e negative regulation of posttranscriptional gene silencing 2/100 20/19669 0.0045805585541132 8 2 0.0484789058185174 3569, 5468 GO:1904752 BP e regulation of vascular associated smooth muscle cell migration 2/100 20/19669 0.0045805585541132 8 2 0.0484789058185174 4780, 9370 GO:0060967 BP e negative regulation of gene silencing by RNA 2/100 20/19669 0.0045805585541132 8 2 0.0484789058185174 3569, 5468 GO:0090189 BP e regulation of branching involved in ureteric bud morphogenesis 2/100 20/19669 0.0045805585541132 6 2 0.0484789058185174 183, 7422 GO:0002726 BP e positive regulation of T cell cytokine production 2/100 20/19669 0.0045805585541132 9 2 0.0484789058185174 3553, 3569 GO:1904996 BP e positive regulation of leukocyte adhesion to vascular endothelial cell 2/100 20/19669 0.0045805585541132 8 2 0.0484789058185174 3569, 3654 GO:0002360 BP e T cell lineage commitment 2/100 20/19669 0.0045805585541132 4 2 0.0484789058185174 3569, 5591 GO:0050900 BP e leukocyte migration 6/100 304/19669 0.0045936634355794 5 6 0.0484789058185174 3146, 3569, 3627, 4318, 6347, 729230 GO:0008630 BP e intrinsic apoptotic signaling pathway in response to DNA damage 3/100 66/19669 0.004627351164206 7 3 0.0484789058185174 581, 3162, 5591 GO:0046637 BP e regulation of alpha-beta T cell differentiation 3/100 66/19669 0.004627351164206 9 3 0.0484789058185174 3146, 3458, 4860 GO:0000122 BP e negative regulation of transcription by RNA polymerase II 11/100 872/19669 0.0047482095921385 11 11 0.0484789058185174 2023, 3146, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9971 GO:1901990 BP e regulation of mitotic cell cycle phase transition 7/100 407/19669 0.0047503822505723 7 7 0.0484789058185174 351, 581, 5591, 6347, 7846, 10383, 23476 GO:0046626 BP e regulation of insulin receptor signaling pathway 3/100 67/19669 0.0048265804190396 6 3 0.0484789058185174 3553, 5580, 9971 GO:0001822 BP e kidney development 4/100 134/19669 0.0048768049152329 4 4 0.0484789058185174 183, 581, 7422, 9104 GO:0009150 BP e purine ribonucleotide metabolic process 6/100 308/19669 0.0048920147515923 9 6 0.0484789058185174 229, 1737, 2023, 2180, 2194, 4831 GO:0002792 BP e negative regulation of peptide secretion 3/100 68/19669 0.0050309235891032 9 3 0.0484789058185174 348, 3553, 5071 GO:0051966 BP e regulation of synaptic transmission, glutamatergic 3/100 68/19669 0.0050309235891032 7 3 0.0484789058185174 5663, 6347, 729230 GO:1902992 BP e negative regulation of amyloid precursor protein catabolic process 2/100 21/19669 0.0050460198582378 7 2 0.0484789058185174 348, 3479 GO:0002052 BP e positive regulation of neuroblast proliferation 2/100 21/19669 0.0050460198582378 8 2 0.0484789058185174 4851, 7422 GO:0032682 BP e negative regulation of chemokine production 2/100 21/19669 0.0050460198582378 8 2 0.0484789058185174 3569, 9971 GO:2001026 BP e regulation of endothelial cell chemotaxis 2/100 21/19669 0.0050460198582378 9 2 0.0484789058185174 4851, 7422 GO:0048710 BP e regulation of astrocyte differentiation 2/100 21/19669 0.0050460198582378 6 2 0.0484789058185174 3569, 4851 GO:2000047 BP e regulation of cell-cell adhesion mediated by cadherin 2/100 21/19669 0.0050460198582378 6 2 0.0484789058185174 4851, 7422 GO:0070266 BP e necroptotic process 2/100 21/19669 0.0050460198582378 5 2 0.0484789058185174 5836, 11035 GO:2000737 BP e negative regulation of stem cell differentiation 2/100 21/19669 0.0050460198582378 6 2 0.0484789058185174 4780, 4851 GO:0014912 BP e negative regulation of smooth muscle cell migration 2/100 21/19669 0.0050460198582378 8 2 0.0484789058185174 4780, 9370 GO:0034142 BP e toll-like receptor 4 signaling pathway 2/100 21/19669 0.0050460198582378 7 2 0.0484789058185174 3654, 9971 GO:0042982 BP e amyloid precursor protein metabolic process 2/100 21/19669 0.0050460198582378 5 2 0.0484789058185174 348, 5663 GO:1903672 BP e positive regulation of sprouting angiogenesis 2/100 21/19669 0.0050460198582378 8 2 0.0484789058185174 3146, 7422 GO:0071453 BP e cellular response to oxygen levels 4/100 137/19669 0.0052725665267704 4 4 0.0502444574904005 3162, 3654, 5468, 7422 GO:0051480 BP e regulation of cytosolic calcium ion concentration 6/100 313/19669 0.0052847486398478 10 6 0.0503293821579564 581, 3064, 3146, 3627, 6622, 729230 GO:0045892 BP e negative regulation of transcription, DNA-templated 14/100 1239/19669 0.0054109308426654 10 14 0.051499211916278 196, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9370, 9971 GO:1903507 BP e negative regulation of nucleic acid-templated transcription 14/100 1241/19669 0.0054518370497289 9 14 0.0517914458599854 196, 2023, 3146, 3440, 3458, 4851, 5071, 5465, 5468, 5663, 6622, 7422, 9370, 9971 GO:0046579 BP e positive regulation of Ras protein signal transduction 3/100 70/19669 0.0054550964092941 9 3 0.0517914458599854 335, 3479, 4851 GO:1902930 BP e regulation of alcohol biosynthetic process 3/100 70/19669 0.0054550964092941 5 3 0.0517914458599854 348, 2194, 6622 GO:0051881 BP e regulation of mitochondrial membrane potential 3/100 70/19669 0.0054550964092941 4 3 0.0517914458599854 581, 4137, 5071 GO:0042738 BP e exogenous drug catabolic process 2/100 22/19669 0.0055323165254687 5 2 0.05207483261588 1559, 1571 GO:0055093 BP e response to hyperoxia 2/100 22/19669 0.0055323165254687 5 2 0.05207483261588 847, 5468 GO:0010640 BP e regulation of platelet-derived growth factor receptor signaling pathway 2/100 22/19669 0.0055323165254687 6 2 0.05207483261588 6622, 9370 GO:0090312 BP e positive regulation of protein deacetylation 2/100 22/19669 0.0055323165254687 9 2 0.05207483261588 3458, 7422 GO:0050886 BP e endocrine process 2/100 22/19669 0.0055323165254687 3 2 0.05207483261588 183, 4846 GO:0002710 BP e negative regulation of T cell mediated immunity 2/100 22/19669 0.0055323165254687 8 2 0.05207483261588 383, 3440 GO:0036336 BP e dendritic cell migration 2/100 22/19669 0.0055323165254687 7 2 0.05207483261588 3146, 729230 GO:0090208 BP e positive regulation of triglyceride metabolic process 2/100 22/19669 0.0055323165254687 7 2 0.05207483261588 335, 9104 GO:0051004 BP e regulation of lipoprotein lipase activity 2/100 22/19669 0.0055323165254687 6 2 0.05207483261588 335, 350 GO:0032069 BP e regulation of nuclease activity 2/100 22/19669 0.0055323165254687 5 2 0.05207483261588 3146, 5580 GO:0031103 BP e axon regeneration 2/100 22/19669 0.0055323165254687 8 2 0.05207483261588 335, 1719 GO:0042093 BP e T-helper cell differentiation 2/100 22/19669 0.0055323165254687 11 2 0.05207483261588 3146, 3569 GO:0001990 BP e regulation of systemic arterial blood pressure by hormone 2/100 22/19669 0.0055323165254687 6 2 0.05207483261588 183, 4846 GO:0002294 BP e CD4-positive, alpha-beta T cell differentiation involved in immune response 2/100 22/19669 0.0055323165254687 10 2 0.05207483261588 3146, 3569 GO:0007005 BP e mitochondrion organization 6/100 317/19669 0.005615238523773 5 6 0.0528230567731463 581, 4137, 4846, 5071, 9474, 81631 GO:0002433 BP e immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 3/100 71/19669 0.0056749960744232 7 3 0.0532549936496179 60, 5580, 10096 GO:1903008 BP e organelle disassembly 3/100 71/19669 0.0056749960744232 5 3 0.0532549936496179 5071, 9474, 81631 GO:0032272 BP e negative regulation of protein polymerization 3/100 71/19669 0.0056749960744232 7 3 0.0532549936496179 2934, 5580, 6622 GO:0038096 BP e Fc-gamma receptor signaling pathway involved in phagocytosis 3/100 71/19669 0.0056749960744232 10 3 0.0532549936496179 60, 5580, 10096 GO:0045165 BP e cell fate commitment 4/100 141/19669 0.0058329589005297 3 4 0.054703983838606 3569, 4851, 5468, 5591 GO:0038094 BP e Fc-gamma receptor signaling pathway 3/100 72/19669 0.0059001497050078 8 3 0.055300428721115 60, 5580, 10096 GO:0033139 BP e regulation of peptidyl-serine phosphorylation of STAT protein 2/100 23/19669 0.0060392290021592 10 2 0.056159356098629 3440, 3458 GO:0051000 BP e positive regulation of nitric-oxide synthase activity 2/100 23/19669 0.0060392290021592 7 2 0.056159356098629 348, 1719 GO:0002293 BP e alpha-beta T cell differentiation involved in immune response 2/100 23/19669 0.0060392290021592 9 2 0.056159356098629 3146, 3569 GO:1903901 BP e negative regulation of viral life cycle 2/100 23/19669 0.0060392290021592 6 2 0.056159356098629 2934, 3440 GO:0002287 BP e alpha-beta T cell activation involved in immune response 2/100 23/19669 0.0060392290021592 7 2 0.056159356098629 3146, 3569 GO:0002262 BP e myeloid cell homeostasis 2/100 23/19669 0.0060392290021592 5 2 0.056159356098629 581, 3162 GO:1901984 BP e negative regulation of protein acetylation 2/100 23/19669 0.0060392290021592 9 2 0.056159356098629 6622, 9474 GO:0030194 BP e positive regulation of blood coagulation 2/100 23/19669 0.0060392290021592 8 2 0.056159356098629 350, 4780 GO:0003044 BP e regulation of systemic arterial blood pressure mediated by a chemical signal 2/100 23/19669 0.0060392290021592 5 2 0.056159356098629 183, 4846 GO:0033032 BP e regulation of myeloid cell apoptotic process 2/100 23/19669 0.0060392290021592 7 2 0.056159356098629 350, 9370 GO:0072132 BP e mesenchyme morphogenesis 2/100 23/19669 0.0060392290021592 4 2 0.056159356098629 4846, 4851 GO:0140354 BP e lipid import into cell 2/100 23/19669 0.0060392290021592 8 2 0.056159356098629 2180, 5663 GO:1900048 BP e positive regulation of hemostasis 2/100 23/19669 0.0060392290021592 5 2 0.056159356098629 350, 4780 GO:0034103 BP e regulation of tissue remodeling 3/100 73/19669 0.0061305900038222 4 3 0.0569745049268266 3569, 5166, 6696 GO:0009259 BP e ribonucleotide metabolic process 6/100 325/19669 0.0063213201275787 8 6 0.0587115973225329 229, 1737, 2023, 2180, 2194, 4831 GO:1901983 BP e regulation of protein acetylation 3/100 74/19669 0.0063663487695111 8 3 0.0589874217716899 3553, 6622, 9474 GO:0072676 BP e lymphocyte migration 3/100 74/19669 0.0063663487695111 7 3 0.0589874217716899 3627, 6347, 729230 GO:0002431 BP e Fc receptor mediated stimulatory signaling pathway 3/100 74/19669 0.0063663487695111 9 3 0.0589874217716899 60, 5580, 10096 GO:0001678 BP e cellular glucose homeostasis 3/100 74/19669 0.0063663487695111 7 3 0.0589874217716899 2081, 4831, 9971 GO:0022607 BP e cellular component assembly 21/100 2258/19669 0.0065277095995868 4 21 0.0604461195774015 60, 229, 302, 335, 348, 351, 2243, 2934, 3146, 4137, 4143, 4851, 5071, 5591, 5663, 6622, 9131, 9474, 9971, 10096, 81631 GO:0042104 BP e positive regulation of activated T cell proliferation 2/100 24/19669 0.0065665393896087 10 2 0.0604781814518722 3146, 3479 GO:0001773 BP e myeloid dendritic cell activation 2/100 24/19669 0.0065665393896087 5 2 0.0604781814518722 3146, 5663 GO:0051354 BP e negative regulation of oxidoreductase activity 2/100 24/19669 0.0065665393896087 5 2 0.0604781814518722 5071, 6622 GO:0031338 BP e regulation of vesicle fusion 2/100 24/19669 0.0065665393896087 6 2 0.0604781814518722 302, 6622 GO:0045662 BP e negative regulation of myoblast differentiation 2/100 24/19669 0.0065665393896087 6 2 0.0604781814518722 3627, 4851 GO:0042737 BP e drug catabolic process 2/100 24/19669 0.0065665393896087 4 2 0.0604781814518722 1559, 1571 GO:2000209 BP e regulation of anoikis 2/100 24/19669 0.0065665393896087 7 2 0.0604781814518722 4851, 5166 GO:0034383 BP e low-density lipoprotein particle clearance 2/100 24/19669 0.0065665393896087 3 2 0.0604781814518722 3162, 9370 GO:0010954 BP e positive regulation of protein processing 2/100 24/19669 0.0065665393896087 9 2 0.0604781814518722 2023, 2934 GO:0009152 BP e purine ribonucleotide biosynthetic process 4/100 146/19669 0.0065876065273564 10 4 0.0606359237177129 1737, 2180, 2194, 4831 GO:0051494 BP e negative regulation of cytoskeleton organization 4/100 147/19669 0.0067459290592098 7 4 0.0620560957688222 2934, 5071, 5580, 6622 GO:0051057 BP e positive regulation of small GTPase mediated signal transduction 3/100 76/19669 0.0068539444438049 8 3 0.0629744507403926 335, 3479, 4851 GO:0070585 BP e protein localization to mitochondrion 3/100 76/19669 0.0068539444438049 6 3 0.0629744507403926 581, 5071, 9131 GO:0061418 BP e regulation of transcription from RNA polymerase II promoter in response to hypoxia 3/100 77/19669 0.0071058405258094 12 3 0.0649376890559158 4780, 4851, 7422 GO:0046651 BP e lymphocyte proliferation 3/100 77/19669 0.0071058405258094 5 3 0.0649376890559158 581, 3440, 5580 GO:0032481 BP e positive regulation of type I interferon production 3/100 77/19669 0.0071058405258094 8 3 0.0649376890559158 3146, 3654, 5591 GO:0045010 BP e actin nucleation 2/100 25/19669 0.0071140314326363 12 2 0.0649376890559158 2934, 10096 GO:0033344 BP e cholesterol efflux 2/100 25/19669 0.0071140314326363 10 2 0.0649376890559158 335, 348 GO:0033280 BP e response to vitamin D 2/100 25/19669 0.0071140314326363 7 2 0.0649376890559158 3627, 6696 GO:2000679 BP e positive regulation of transcription regulatory region DNA binding 2/100 25/19669 0.0071140314326363 6 2 0.0649376890559158 3458, 3479 GO:0001504 BP e neurotransmitter uptake 2/100 25/19669 0.0071140314326363 5 2 0.0649376890559158 5071, 6622 GO:0009065 BP e glutamine family amino acid catabolic process 2/100 25/19669 0.0071140314326363 9 2 0.0649376890559158 383, 4846 GO:0002292 BP e T cell differentiation involved in immune response 2/100 25/19669 0.0071140314326363 8 2 0.0649376890559158 3146, 3569 GO:0071887 BP e leukocyte apoptotic process 2/100 25/19669 0.0071140314326363 5 2 0.0649376890559158 581, 3569 GO:0032943 BP e mononuclear cell proliferation 3/100 78/19669 0.0073631734422328 4 3 0.0671322507559027 581, 3440, 5580 GO:0010770 BP e positive regulation of cell morphogenesis involved in differentiation 3/100 78/19669 0.0073631734422328 7 3 0.0671322507559027 335, 2243, 5591 GO:0051604 BP e protein maturation 5/100 238/19669 0.0073824386823234 5 5 0.0672680469632669 350, 1510, 2243, 5327, 5663 GO:0050770 BP e regulation of axonogenesis 4/100 151/19669 0.0074044201451724 8 4 0.0674284177717182 4137, 5663, 6696, 7422 GO:1901987 BP e regulation of cell cycle phase transition 7/100 443/19669 0.0074531519108609 6 7 0.0678320567168246 351, 581, 5591, 6347, 7846, 10383, 23476 GO:1903708 BP e positive regulation of hemopoiesis 4/100 152/19669 0.0075754248780204 6 4 0.06886343111207 3146, 3458, 4860, 5591 GO:1902107 BP e positive regulation of leukocyte differentiation 4/100 152/19669 0.0075754248780204 7 4 0.06886343111207 3146, 3458, 4860, 5591 GO:0051153 BP e regulation of striated muscle cell differentiation 3/100 79/19669 0.0076259706273854 6 3 0.0692143670690101 3479, 4851, 5465 GO:0042632 BP e cholesterol homeostasis 3/100 79/19669 0.0076259706273854 7 3 0.0692143670690101 335, 348, 9971 GO:0002250 BP e adaptive immune response 5/100 240/19669 0.0076399779411979 3 5 0.0692143670690101 383, 2243, 3440, 3458, 5580 GO:1904019 BP e epithelial cell apoptotic process 2/100 26/19669 0.0076814905103228 5 2 0.0692143670690101 2934, 4217 GO:0045606 BP e positive regulation of epidermal cell differentiation 2/100 26/19669 0.0076814905103228 7 2 0.0692143670690101 4831, 4851 GO:1903579 BP e negative regulation of ATP metabolic process 2/100 26/19669 0.0076814905103228 5 2 0.0692143670690101 5465, 6622 GO:0002675 BP e positive regulation of acute inflammatory response 2/100 26/19669 0.0076814905103228 8 2 0.0692143670690101 3553, 3569 GO:0048679 BP e regulation of axon regeneration 2/100 26/19669 0.0076814905103228 9 2 0.0692143670690101 2896, 6696 GO:0018904 BP e ether metabolic process 2/100 26/19669 0.0076814905103228 3 2 0.0692143670690101 2052, 2194 GO:0006760 BP e folic acid-containing compound metabolic process 2/100 26/19669 0.0076814905103228 5 2 0.0692143670690101 1719, 4524 GO:0006706 BP e steroid catabolic process 2/100 26/19669 0.0076814905103228 5 2 0.0692143670690101 348, 6696 GO:0070633 BP e transepithelial transport 2/100 26/19669 0.0076814905103228 4 2 0.0692143670690101 1244, 5243 GO:1903319 BP e positive regulation of protein maturation 2/100 26/19669 0.0076814905103228 7 2 0.0692143670690101 2023, 2934 GO:0014904 BP e myotube cell development 2/100 26/19669 0.0076814905103228 5 2 0.0692143670690101 2876, 3479 GO:0010614 BP e negative regulation of cardiac muscle hypertrophy 2/100 26/19669 0.0076814905103228 8 2 0.0692143670690101 4851, 5465 GO:0071695 BP e anatomical structure maturation 4/100 153/19669 0.0077490145878566 3 4 0.0697819394424308 351, 4313, 5468, 7422 GO:0030838 BP e positive regulation of actin filament polymerization 3/100 80/19669 0.0078942586734144 11 3 0.070882520994077 1440, 2934, 10096 GO:0055072 BP e iron ion homeostasis 3/100 80/19669 0.0078942586734144 9 3 0.070882520994077 1356, 3162, 3934 GO:0070098 BP e chemokine-mediated signaling pathway 3/100 80/19669 0.0078942586734144 7 3 0.070882520994077 3627, 6347, 729230 GO:0009914 BP e hormone transport 3/100 80/19669 0.0078942586734144 4 3 0.070882520994077 1244, 3569, 7276 GO:0055092 BP e sterol homeostasis 3/100 80/19669 0.0078942586734144 6 3 0.070882520994077 335, 348, 9971 GO:0034249 BP e negative regulation of cellular amide metabolic process 4/100 154/19669 0.0079252051191195 6 4 0.0711188960835277 348, 1719, 3479, 83667 GO:0003012 BP e muscle system process 5/100 243/19669 0.0080379458029031 3 5 0.0720885698756871 2934, 3162, 3479, 3553, 4846 GO:0051726 BP e regulation of cell cycle 13/100 1159/19669 0.008081519039359 4 13 0.0724371450295489 60, 351, 581, 2081, 3458, 3479, 3553, 4851, 5591, 6347, 7846, 10383, 23476 GO:0006164 BP e purine nucleotide biosynthetic process 4/100 155/19669 0.0081040121714269 9 4 0.0725542450949745 1737, 2180, 2194, 4831 GO:2000241 BP e regulation of reproductive process 4/100 155/19669 0.0081040121714269 3 4 0.0725542450949745 3479, 4851, 7422, 9104 GO:0007167 BP e enzyme linked receptor protein signaling pathway 9/100 685/19669 0.0081420044717592 6 9 0.0728520051281245 60, 3479, 4313, 4318, 5166, 5327, 5663, 7422, 10096 GO:0048514 BP e blood vessel morphogenesis 3/100 81/19669 0.0081680633376404 4 3 0.0730427046869765 348, 4851, 7422 GO:0010575 BP e positive regulation of vascular endothelial growth factor production 2/100 27/19669 0.0082687036241488 8 2 0.073346022349078 3553, 3569 GO:0061718 BP e glucose catabolic process to pyruvate 2/100 27/19669 0.0082687036241488 8 2 0.073346022349078 229, 2023 GO:0002825 BP e regulation of T-helper 1 type immune response 2/100 27/19669 0.0082687036241488 7 2 0.073346022349078 3553, 729230 GO:0001659 BP e temperature homeostasis 2/100 27/19669 0.0082687036241488 5 2 0.073346022349078 2876, 3553 GO:0090200 BP e positive regulation of release of cytochrome c from mitochondria 2/100 27/19669 0.0082687036241488 8 2 0.073346022349078 581, 4318 GO:0010971 BP e positive regulation of G2/M transition of mitotic cell cycle 2/100 27/19669 0.0082687036241488 9 2 0.073346022349078 351, 23476 GO:1902742 BP e apoptotic process involved in development 2/100 27/19669 0.0082687036241488 5 2 0.073346022349078 581, 4851 GO:0061621 BP e canonical glycolysis 2/100 27/19669 0.0082687036241488 15 2 0.073346022349078 229, 2023 GO:0019079 BP e viral genome replication 2/100 27/19669 0.0082687036241488 4 2 0.073346022349078 6347, 9474 GO:0090140 BP e regulation of mitochondrial fission 2/100 27/19669 0.0082687036241488 7 2 0.073346022349078 4137, 5071 GO:0006735 BP e NADH regeneration 2/100 27/19669 0.0082687036241488 3 2 0.073346022349078 229, 2023 GO:0043367 BP e CD4-positive, alpha-beta T cell differentiation 2/100 27/19669 0.0082687036241488 9 2 0.073346022349078 3146, 3569 GO:0031102 BP e neuron projection regeneration 2/100 27/19669 0.0082687036241488 7 2 0.073346022349078 335, 1719 GO:1904994 BP e regulation of leukocyte adhesion to vascular endothelial cell 2/100 27/19669 0.0082687036241488 7 2 0.073346022349078 3569, 3654 GO:0042113 BP e B cell activation 4/100 156/19669 0.0082854512996349 5 4 0.073452243952409 581, 3440, 3569, 5580 GO:0009132 BP e nucleoside diphosphate metabolic process 3/100 82/19669 0.0084474095561549 7 3 0.0748449240467612 229, 2023, 4831 GO:0006839 BP e mitochondrial transport 4/100 157/19669 0.0084695379114458 4 4 0.0749978069373718 581, 5071, 5663, 9131 GO:0009260 BP e ribonucleotide biosynthetic process 4/100 159/19669 0.0088457144786927 9 4 0.0780201785973237 1737, 2180, 2194, 4831 GO:1903427 BP e negative regulation of reactive oxygen species biosynthetic process 2/100 28/19669 0.0088754593849333 7 2 0.0780201785973237 5465, 9104 GO:0061615 BP e glycolytic process through fructose-6-phosphate 2/100 28/19669 0.0088754593849333 13 2 0.0780201785973237 229, 2023 GO:0071480 BP e cellular response to gamma radiation 2/100 28/19669 0.0088754593849333 7 2 0.0780201785973237 3309, 50507 GO:0061620 BP e glycolytic process through glucose-6-phosphate 2/100 28/19669 0.0088754593849333 14 2 0.0780201785973237 229, 2023 GO:0014741 BP e negative regulation of muscle hypertrophy 2/100 28/19669 0.0088754593849333 7 2 0.0780201785973237 4851, 5465 GO:0019915 BP e lipid storage 2/100 28/19669 0.0088754593849333 4 2 0.0780201785973237 335, 3553 GO:0042744 BP e hydrogen peroxide catabolic process 2/100 28/19669 0.0088754593849333 5 2 0.0780201785973237 847, 2876 GO:0035987 BP e endodermal cell differentiation 2/100 28/19669 0.0088754593849333 4 2 0.0780201785973237 4313, 4318 GO:0032691 BP e negative regulation of interleukin-1 beta production 2/100 28/19669 0.0088754593849333 9 2 0.0780201785973237 335, 3479 GO:0046685 BP e response to arsenic-containing substance 2/100 28/19669 0.0088754593849333 3 2 0.0780201785973237 1244, 3162 GO:0034377 BP e plasma lipoprotein particle assembly 2/100 28/19669 0.0088754593849333 7 2 0.0780201785973237 335, 348 GO:0031330 BP e negative regulation of cellular catabolic process 5/100 249/19669 0.0088767597611379 6 5 0.0780201785973237 302, 3162, 5663, 6622, 9104 GO:1901606 BP e alpha-amino acid catabolic process 3/100 84/19669 0.0090228223317906 8 3 0.0792586961679551 383, 4143, 4846 GO:0016241 BP e regulation of macroautophagy 4/100 160/19669 0.0090378345092523 7 4 0.0793452784354782 2081, 3064, 3162, 83667 GO:0043433 BP e negative regulation of DNA-binding transcription factor activity 4/100 161/19669 0.0092326621739712 11 4 0.0810095044797135 847, 3162, 3654, 9971 GO:0032088 BP e negative regulation of NF-kappaB transcription factor activity 3/100 85/19669 0.0093189347258291 12 3 0.0815875947703182 847, 3654, 9971 GO:0002443 BP e leukocyte mediated immunity 3/100 85/19669 0.0093189347258291 3 3 0.0815875947703182 3569, 5580, 10383 GO:0045921 BP e positive regulation of exocytosis 3/100 85/19669 0.0093189347258291 8 3 0.0815875947703182 2243, 3458, 6622 GO:0010665 BP e regulation of cardiac muscle cell apoptotic process 2/100 29/19669 0.0095015480084472 9 2 0.0815875947703182 4217, 4780 GO:0042417 BP e dopamine metabolic process 2/100 29/19669 0.0095015480084472 8 2 0.0815875947703182 5071, 6622 GO:0071549 BP e cellular response to dexamethasone stimulus 2/100 29/19669 0.0095015480084472 9 2 0.0815875947703182 383, 1244 GO:0036296 BP e response to increased oxygen levels 2/100 29/19669 0.0095015480084472 4 2 0.0815875947703182 847, 5468 GO:0034405 BP e response to fluid shear stress 2/100 29/19669 0.0095015480084472 3 2 0.0815875947703182 4780, 4846 GO:0042310 BP e vasoconstriction 2/100 29/19669 0.0095015480084472 7 2 0.0815875947703182 183, 1401 GO:0070570 BP e regulation of neuron projection regeneration 2/100 29/19669 0.0095015480084472 8 2 0.0815875947703182 2896, 6696 GO:0070168 BP e negative regulation of biomineral tissue development 2/100 29/19669 0.0095015480084472 6 2 0.0815875947703182 4846, 4851 GO:1903409 BP e reactive oxygen species biosynthetic process 2/100 29/19669 0.0095015480084472 4 2 0.0815875947703182 4846, 50507 GO:2000352 BP e negative regulation of endothelial cell apoptotic process 2/100 29/19669 0.0095015480084472 9 2 0.0815875947703182 2243, 4780 GO:0051781 BP e positive regulation of cell division 3/100 86/19669 0.0096206803658355 5 3 0.0815875947703182 847, 3553, 7422 GO:0042058 BP e regulation of epidermal growth factor receptor signaling pathway 3/100 86/19669 0.0096206803658355 7 3 0.0815875947703182 183, 4318, 5663 GO:0031058 BP e positive regulation of histone modification 3/100 86/19669 0.0096206803658355 9 3 0.0815875947703182 3553, 7422, 23476 GO:0007267 BP e cell-cell signaling 8/100 582/19669 0.0096435859249626 3 8 0.0815875947703182 183, 348, 3440, 3553, 3627, 4137, 5071, 6622 GO:0072330 BP e monocarboxylic acid biosynthetic process 4/100 164/19669 0.0098335368482718 7 4 0.0815875947703182 1559, 1571, 2194, 2944 GO:0046620 BP e regulation of organ growth 3/100 87/19669 0.0099280802099901 5 3 0.0815875947703182 3479, 4851, 5465 GO:0031214 BP e biomineral tissue development 3/100 87/19669 0.0099280802099901 4 3 0.0815875947703182 3479, 5465, 6696 GO:0110148 BP e biomineralization 3/100 87/19669 0.0099280802099901 1 3 0.0815875947703182 3479, 5465, 6696 GO:0002833 BP e positive regulation of response to biotic stimulus 5/100 256/19669 0.0099298156628014 5 5 0.0815875947703182 383, 2896, 3146, 5580, 5591 GO:0006417 BP e regulation of translation 6/100 359/19669 0.0100580695272042 7 6 0.0815875947703182 351, 1719, 3569, 5591, 83667, 136319 GO:0099174 BP e regulation of presynapse organization 2/100 30/19669 0.0101467612989206 6 2 0.0815875947703182 351, 6622 GO:0055023 BP e positive regulation of cardiac muscle tissue growth 2/100 30/19669 0.0101467612989206 8 2 0.0815875947703182 3479, 4851 GO:0006084 BP e acetyl-CoA metabolic process 2/100 30/19669 0.0101467612989206 11 2 0.0815875947703182 1737, 2194 GO:0035633 BP e maintenance of blood-brain barrier 2/100 30/19669 0.0101467612989206 6 2 0.0815875947703182 60, 3569 GO:1902751 BP e positive regulation of cell cycle G2/M phase transition 2/100 30/19669 0.0101467612989206 8 2 0.0815875947703182 351, 23476 GO:1902692 BP e regulation of neuroblast proliferation 2/100 30/19669 0.0101467612989206 6 2 0.0815875947703182 4851, 7422 GO:0007176 BP e regulation of epidermal growth factor-activated receptor activity 2/100 30/19669 0.0101467612989206 11 2 0.0815875947703182 351, 5663 GO:0051968 BP e positive regulation of synaptic transmission, glutamatergic 2/100 30/19669 0.0101467612989206 8 2 0.0815875947703182 6347, 729230 GO:0110150 BP e negative regulation of biomineralization 2/100 30/19669 0.0101467612989206 4 2 0.0815875947703182 4846, 4851 GO:1905606 BP e regulation of presynapse assembly 2/100 30/19669 0.0101467612989206 7 2 0.0815875947703182 351, 6622 GO:0048147 BP e negative regulation of fibroblast proliferation 2/100 30/19669 0.0101467612989206 6 2 0.0815875947703182 581, 5468 GO:0032743 BP e positive regulation of interleukin-2 production 2/100 30/19669 0.0101467612989206 8 2 0.0815875947703182 3553, 729230 GO:0055013 BP e cardiac muscle cell development 2/100 30/19669 0.0101467612989206 5 2 0.0815875947703182 7422, 9474 GO:0032436 BP e positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3/100 88/19669 0.0102411544490303 11 3 0.0823035858854188 4780, 5071, 5663 GO:0015914 BP e phospholipid transport 3/100 89/19669 0.0105599225152043 8 3 0.0847768427276967 335, 348, 5243 GO:1901532 BP e regulation of hematopoietic progenitor cell differentiation 3/100 89/19669 0.0105599225152043 5 3 0.0847768427276967 4780, 4851, 5591 GO:1903146 BP e regulation of autophagy of mitochondrion 2/100 31/19669 0.0108108926405513 7 2 0.0862517562146633 3064, 5071 GO:0051955 BP e regulation of amino acid transport 2/100 31/19669 0.0108108926405513 8 2 0.0862517562146633 383, 5663 GO:0010662 BP e regulation of striated muscle cell apoptotic process 2/100 31/19669 0.0108108926405513 8 2 0.0862517562146633 4217, 4780 GO:0002040 BP e sprouting angiogenesis 2/100 31/19669 0.0108108926405513 4 2 0.0862517562146633 4851, 7422 GO:0046427 BP e positive regulation of receptor signaling pathway via JAK-STAT 2/100 31/19669 0.0108108926405513 8 2 0.0862517562146633 3569, 4851 GO:0006007 BP e glucose catabolic process 2/100 31/19669 0.0108108926405513 7 2 0.0862517562146633 229, 2023 GO:0003180 BP e aortic valve morphogenesis 2/100 31/19669 0.0108108926405513 4 2 0.0862517562146633 4846, 4851 GO:0035710 BP e CD4-positive, alpha-beta T cell activation 2/100 31/19669 0.0108108926405513 7 2 0.0862517562146633 3146, 3569 GO:0045070 BP e positive regulation of viral genome replication 2/100 31/19669 0.0108108926405513 7 2 0.0862517562146633 4851, 5465 GO:0045684 BP e positive regulation of epidermis development 2/100 31/19669 0.0108108926405513 5 2 0.0862517562146633 4831, 4851 GO:0046949 BP e fatty-acyl-CoA biosynthetic process 2/100 31/19669 0.0108108926405513 12 2 0.0862517562146633 2180, 2194 GO:0032660 BP e regulation of interleukin-17 production 2/100 31/19669 0.0108108926405513 7 2 0.0862517562146633 3458, 3569 GO:0043648 BP e dicarboxylic acid metabolic process 3/100 91/19669 0.0112146141216626 6 3 0.0891953030141543 1719, 4199, 4524 GO:0071346 BP e cellular response to interferon-gamma 3/100 91/19669 0.0112146141216626 6 3 0.0891953030141543 2934, 6347, 10096 GO:0010717 BP e regulation of epithelial to mesenchymal transition 3/100 91/19669 0.0112146141216626 5 3 0.0891953030141543 3553, 3569, 4851 GO:0070661 BP e leukocyte proliferation 3/100 91/19669 0.0112146141216626 3 3 0.0891953030141543 581, 3440, 5580 GO:0048524 BP e positive regulation of viral process 3/100 91/19669 0.0112146141216626 5 3 0.0891953030141543 4851, 5091, 5465 GO:0062014 BP e negative regulation of small molecule metabolic process 3/100 91/19669 0.0112146141216626 5 3 0.0891953030141543 348, 5465, 9370 GO:0042558 BP e pteridine-containing compound metabolic process 2/100 32/19669 0.0114937369880352 4 2 0.0911796970339493 1719, 4524 GO:0015721 BP e bile acid and bile salt transport 2/100 32/19669 0.0114937369880352 10 2 0.0911796970339493 1244, 9971 GO:0065005 BP e protein-lipid complex assembly 2/100 32/19669 0.0114937369880352 6 2 0.0911796970339493 335, 348 GO:0098801 BP e regulation of renal system process 2/100 32/19669 0.0114937369880352 5 2 0.0911796970339493 183, 9370 GO:0033077 BP e T cell differentiation in thymus 2/100 32/19669 0.0114937369880352 8 2 0.0911796970339493 5591, 11035 GO:0030516 BP e regulation of axon extension 3/100 92/19669 0.0115505728143052 7 3 0.0915833671366087 348, 4137, 7422 GO:0048167 BP e regulation of synaptic plasticity 4/100 173/19669 0.0117869748403393 7 4 0.0934096512836368 348, 351, 4137, 5663 GO:1901184 BP e regulation of ERBB signaling pathway 3/100 93/19669 0.0118922956590187 6 3 0.0941473406338986 183, 4318, 5663 GO:0006576 BP e cellular biogenic amine metabolic process 3/100 93/19669 0.0118922956590187 6 3 0.0941473406338986 5071, 6622, 136319 GO:0010921 BP e regulation of phosphatase activity 4/100 174/19669 0.0120182806093729 8 4 0.0950958038962721 3064, 3458, 9104, 11035 GO:0016444 BP e somatic cell DNA recombination 2/100 33/19669 0.0121950908555297 8 2 0.0960012523102831 3146, 5591 GO:1905332 BP e positive regulation of morphogenesis of an epithelium 2/100 33/19669 0.0121950908555297 6 2 0.0960012523102831 183, 7422 GO:0002562 BP e somatic diversification of immune receptors via germline recombination within a single locus 2/100 33/19669 0.0121950908555297 9 2 0.0960012523102831 3146, 5591 GO:0048536 BP e spleen development 2/100 33/19669 0.0121950908555297 5 2 0.0960012523102831 5591, 11035 GO:0002691 BP e regulation of cellular extravasation 2/100 33/19669 0.0121950908555297 8 2 0.0960012523102831 11035, 729230 GO:0014059 BP e regulation of dopamine secretion 2/100 33/19669 0.0121950908555297 9 2 0.0960012523102831 5071, 6622 GO:0060969 BP e negative regulation of gene silencing 2/100 33/19669 0.0121950908555297 7 2 0.0960012523102831 3569, 5468 GO:0070050 BP e neuron cellular homeostasis 2/100 33/19669 0.0121950908555297 5 2 0.0960012523102831 3569, 5071 GO:0051154 BP e negative regulation of striated muscle cell differentiation 2/100 33/19669 0.0121950908555297 7 2 0.0960012523102831 4851, 5465 GO:0002437 BP e inflammatory response to antigenic stimulus 2/100 33/19669 0.0121950908555297 5 2 0.0960012523102831 3146, 4851 GO:0045444 BP e fat cell differentiation 3/100 94/19669 0.0122397984284959 4 3 0.0962547255056474 2876, 5468, 9370 GO:0010769 BP e regulation of cell morphogenesis involved in differentiation 3/100 94/19669 0.0122397984284959 6 3 0.0962547255056474 335, 2243, 5591 GO:0031345 BP e negative regulation of cell projection organization 4/100 175/19669 0.0122524853621403 6 4 0.0963052858648315 348, 5580, 5663, 6696 GO:0022411 BP e cellular component disassembly 6/100 375/19669 0.0122738531753608 4 6 0.0964239920208289 2934, 4313, 4318, 5071, 9474, 81631 GO:0032535 BP e regulation of cellular component size 5/100 270/19669 0.0122879352898851 4 5 0.0964853694445575 1440, 2934, 5580, 10096, 136319 GO:0060191 BP e regulation of lipase activity 3/100 95/19669 0.012593096191364 5 3 0.0988310812774563 335, 350, 6622 GO:0000083 BP e regulation of transcription involved in G1/S transition of mitotic cell cycle 2/100 34/19669 0.0129147523048608 10 2 0.1011491287388339 1719, 23476 GO:0060421 BP e positive regulation of heart growth 2/100 34/19669 0.0129147523048608 7 2 0.1011491287388339 3479, 4851 GO:0055081 BP e anion homeostasis 2/100 34/19669 0.0129147523048608 6 2 0.1011491287388339 1152, 1244 GO:0048008 BP e platelet-derived growth factor receptor signaling pathway 2/100 34/19669 0.0129147523048608 8 2 0.1011491287388339 5327, 7422 GO:0090288 BP e negative regulation of cellular response to growth factor stimulus 3/100 96/19669 0.0129522033175761 5 3 0.1012878094804355 183, 4851, 5468 GO:0006637 BP e acyl-CoA metabolic process 3/100 96/19669 0.0129522033175761 10 3 0.1012878094804355 1737, 2180, 2194 GO:0035383 BP e thioester metabolic process 3/100 96/19669 0.0129522033175761 4 3 0.1012878094804355 1737, 2180, 2194 GO:0090316 BP e positive regulation of intracellular protein transport 4/100 179/19669 0.0132185419019364 10 4 0.1032656649090365 3458, 3553, 5580, 5663 GO:0021700 BP e developmental maturation 4/100 179/19669 0.0132185419019364 2 4 0.1032656649090365 351, 4313, 5468, 7422 GO:0002832 BP e negative regulation of response to biotic stimulus 3/100 97/19669 0.0133171334911331 5 3 0.103877691043355 383, 2896, 5468 GO:0002824 BP e positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/100 97/19669 0.0133171334911331 7 3 0.103877691043355 3553, 3569, 729230 GO:0032869 BP e cellular response to insulin stimulus 3/100 97/19669 0.0133171334911331 8 3 0.103877691043355 5468, 5591, 9370 GO:0048589 BP e developmental growth 5/100 276/19669 0.0134059284203626 2 5 0.1045173446754715 351, 2876, 2934, 4851, 136319 GO:0098657 BP e import into cell 4/100 180/19669 0.0134674259542131 4 4 0.104943638195109 2180, 5071, 5663, 6622 GO:1903047 BP e mitotic cell cycle process 8/100 618/19669 0.0134797531452232 3 8 0.1049865389195275 581, 1719, 3064, 5243, 5591, 7846, 10383, 23476 GO:0071702 BP e organic substance transport 19/100 2109/19669 0.013606498627186 6 19 0.1059200879475941 335, 348, 350, 581, 821, 847, 1244, 2180, 3309, 3569, 5071, 5243, 5468, 5663, 6622, 9131, 9971, 26061, 83667 GO:1904894 BP e positive regulation of receptor signaling pathway via STAT 2/100 35/19669 0.0136525209385889 7 2 0.1059567812631786 3569, 4851 GO:1903725 BP e regulation of phospholipid metabolic process 2/100 35/19669 0.0136525209385889 7 2 0.1059567812631786 5580, 9971 GO:0006656 BP e phosphatidylcholine biosynthetic process 2/100 35/19669 0.0136525209385889 8 2 0.1059567812631786 335, 5130 GO:0046627 BP e negative regulation of insulin receptor signaling pathway 2/100 35/19669 0.0136525209385889 7 2 0.1059567812631786 3553, 5580 GO:0045429 BP e positive regulation of nitric oxide biosynthetic process 2/100 35/19669 0.0136525209385889 8 2 0.1059567812631786 3458, 3553 GO:0044275 BP e cellular carbohydrate catabolic process 2/100 35/19669 0.0136525209385889 5 2 0.1059567812631786 5836, 6652 GO:0032231 BP e regulation of actin filament bundle assembly 3/100 98/19669 0.0136878997134023 9 3 0.1061778107808783 335, 5071, 50507 GO:0006897 BP e endocytosis 6/100 386/19669 0.0139839846694878 5 6 0.1084199113669611 213, 335, 348, 351, 821, 6622 GO:0010564 BP e regulation of cell cycle process 9/100 749/19669 0.0140177662343414 5 9 0.1086271008794134 351, 581, 3479, 3553, 5591, 6347, 7846, 10383, 23476 GO:0040007 BP e growth 5/100 281/19669 0.0143886312402524 1 5 0.1109423577701444 351, 2876, 2934, 4851, 136319 GO:1904407 BP e positive regulation of nitric oxide metabolic process 2/100 36/19669 0.0144081978868115 7 2 0.1109423577701444 3458, 3553 GO:0032965 BP e regulation of collagen biosynthetic process 2/100 36/19669 0.0144081978868115 5 2 0.1109423577701444 3569, 5468 GO:0048488 BP e synaptic vesicle endocytosis 2/100 36/19669 0.0144081978868115 7 2 0.1109423577701444 821, 6622 GO:0140238 BP e presynaptic endocytosis 2/100 36/19669 0.0144081978868115 6 2 0.1109423577701444 821, 6622 GO:0014911 BP e positive regulation of smooth muscle cell migration 2/100 36/19669 0.0144081978868115 8 2 0.1109423577701444 3479, 50507 GO:0007610 BP e behavior 7/100 504/19669 0.0144232630902414 1 7 0.1109423577701444 348, 351, 3064, 4137, 5071, 5465, 5663 GO:0042770 BP e signal transduction in response to DNA damage 3/100 100/19669 0.0144469889598269 6 3 0.1109423577701444 581, 5591, 83667 GO:0045621 BP e positive regulation of lymphocyte differentiation 3/100 100/19669 0.0144469889598269 8 3 0.1109423577701444 3458, 4860, 5591 GO:0001649 BP e osteoblast differentiation 3/100 100/19669 0.0144469889598269 4 3 0.1109423577701444 847, 2194, 6696 GO:1905269 BP e positive regulation of chromatin organization 3/100 100/19669 0.0144469889598269 8 3 0.1109423577701444 3553, 7422, 23476 GO:0048259 BP e regulation of receptor-mediated endocytosis 3/100 100/19669 0.0144469889598269 7 3 0.1109423577701444 302, 7422, 9370 GO:0120032 BP e regulation of plasma membrane bounded cell projection assembly 4/100 184/19669 0.0144927931719047 7 4 0.1109423577701444 3064, 5580, 9474, 10096 GO:0007596 BP e blood coagulation 4/100 185/19669 0.0147566492948536 5 4 0.1109423577701444 2243, 3440, 5327, 7450 GO:2000134 BP e negative regulation of G1/S transition of mitotic cell cycle 3/100 101/19669 0.0148353346621735 9 3 0.1109423577701444 581, 5591, 6347 GO:0030168 BP e platelet activation 3/100 101/19669 0.0148353346621735 3 3 0.1109423577701444 3569, 5580, 7450 GO:0060491 BP e regulation of cell projection assembly 4/100 186/19669 0.0150235332155873 6 4 0.1109423577701444 3064, 5580, 9474, 10096 GO:0070873 BP e regulation of glycogen metabolic process 2/100 37/19669 0.015181585800125 8 2 0.1109423577701444 3146, 3479 GO:1901021 BP e positive regulation of calcium ion transmembrane transporter activity 2/100 37/19669 0.015181585800125 10 2 0.1109423577701444 3064, 9104 GO:0003073 BP e regulation of systemic arterial blood pressure 2/100 37/19669 0.015181585800125 4 2 0.1109423577701444 183, 4846 GO:0001895 BP e retina homeostasis 2/100 37/19669 0.015181585800125 6 2 0.1109423577701444 60, 213 GO:0048713 BP e regulation of oligodendrocyte differentiation 2/100 37/19669 0.015181585800125 6 2 0.1109423577701444 4851, 5468 GO:0033762 BP e response to glucagon 2/100 37/19669 0.015181585800125 7 2 0.1109423577701444 383, 1244 GO:1900077 BP e negative regulation of cellular response to insulin stimulus 2/100 37/19669 0.015181585800125 5 2 0.1109423577701444 3553, 5580 GO:1903670 BP e regulation of sprouting angiogenesis 2/100 37/19669 0.015181585800125 7 2 0.1109423577701444 3146, 7422 GO:0032733 BP e positive regulation of interleukin-10 production 2/100 37/19669 0.015181585800125 8 2 0.1109423577701444 3146, 3569 GO:0002821 BP e positive regulation of adaptive immune response 3/100 102/19669 0.0152295617842926 6 3 0.111187360465021 3553, 3569, 729230 GO:0009063 BP e cellular amino acid catabolic process 3/100 102/19669 0.0152295617842926 7 3 0.111187360465021 383, 4143, 4846 GO:0050817 BP e coagulation 4/100 187/19669 0.0152934556872903 2 4 0.1116008928531999 2243, 3440, 5327, 7450 GO:0030705 BP e cytoskeleton-dependent intracellular transport 4/100 188/19669 0.0155664273055582 5 4 0.1135390124324844 351, 3064, 4137, 7846 GO:1902807 BP e negative regulation of cell cycle G1/S phase transition 3/100 103/19669 0.0156296800506946 8 3 0.113946364746656 581, 5591, 6347 GO:0010608 BP e posttranscriptional regulation of gene expression 7/100 513/19669 0.0157504289178821 6 7 0.1147723016317261 351, 1719, 3569, 5580, 5591, 83667, 136319 GO:0046578 BP e regulation of Ras protein signal transduction 4/100 189/19669 0.0158424585071915 8 4 0.1153469916619592 335, 348, 3479, 4851 GO:0090068 BP e positive regulation of cell cycle process 5/100 288/19669 0.0158442846246511 6 5 0.1153469916619592 351, 581, 3479, 3553, 23476 GO:0045742 BP e positive regulation of epidermal growth factor receptor signaling pathway 2/100 38/19669 0.015972488832846 8 2 0.1160059476816894 183, 4318 GO:0071548 BP e response to dexamethasone 2/100 38/19669 0.015972488832846 8 2 0.1160059476816894 383, 1244 GO:0001541 BP e ovarian follicle development 2/100 38/19669 0.015972488832846 4 2 0.1160059476816894 581, 7422 GO:0046632 BP e alpha-beta T cell differentiation 2/100 38/19669 0.015972488832846 8 2 0.1160059476816894 3146, 3569 GO:0006734 BP e NADH metabolic process 2/100 38/19669 0.015972488832846 2 2 0.1160059476816894 229, 2023 GO:0007219 BP e Notch signaling pathway 3/100 104/19669 0.0160356985526329 6 3 0.1163552101485247 351, 4851, 9971 GO:2000060 BP e positive regulation of ubiquitin-dependent protein catabolic process 3/100 104/19669 0.0160356985526329 10 3 0.1163552101485247 4780, 5071, 5663 GO:0007599 BP e hemostasis 4/100 190/19669 0.0161215595655013 4 4 0.1169230922304736 2243, 3440, 5327, 7450 GO:0046777 BP e protein autophosphorylation 4/100 192/19669 0.016689011555693 8 4 0.1209815769392919 2081, 3654, 4831, 11035 GO:0032689 BP e negative regulation of interferon-gamma production 2/100 39/19669 0.0167807126444461 8 2 0.1214746790207083 3146, 9971 GO:0007257 BP e activation of JUN kinase activity 2/100 39/19669 0.0167807126444461 14 2 0.1214746790207083 2081, 4217 GO:0045773 BP e positive regulation of axon extension 2/100 39/19669 0.0167807126444461 10 2 0.1214746790207083 4137, 7422 GO:0046700 BP e heterocycle catabolic process 6/100 403/19669 0.0169448671651655 4 6 0.1226053153135389 2081, 2876, 3146, 3162, 4780, 4860 GO:1905475 BP e regulation of protein localization to membrane 4/100 193/19669 0.016977382236825 6 4 0.1227251820689228 60, 2934, 3458, 5071 GO:0050808 BP e synapse organization 4/100 193/19669 0.016977382236825 5 4 0.1227251820689228 351, 4137, 5663, 6622 GO:0007613 BP e memory 3/100 107/19669 0.0172892370953452 6 3 0.1248036392576751 348, 4137, 5663 GO:2000278 BP e regulation of DNA biosynthetic process 3/100 107/19669 0.0172892370953452 7 3 0.1248036392576751 5468, 9104, 9370 GO:2001022 BP e positive regulation of response to DNA damage stimulus 3/100 107/19669 0.0172892370953452 7 3 0.1248036392576751 3146, 5580, 5591 GO:0006096 BP e glycolytic process 2/100 40/19669 0.0176060643764754 12 2 0.1267933227674106 229, 2023 GO:0042743 BP e hydrogen peroxide metabolic process 2/100 40/19669 0.0176060643764754 4 2 0.1267933227674106 847, 2876 GO:1901186 BP e positive regulation of ERBB signaling pathway 2/100 40/19669 0.0176060643764754 7 2 0.1267933227674106 183, 4318 GO:0042908 BP e xenobiotic transport 2/100 40/19669 0.0176060643764754 4 2 0.1267933227674106 1244, 5243 GO:0032735 BP e positive regulation of interleukin-12 production 2/100 40/19669 0.0176060643764754 8 2 0.1267933227674106 3146, 3458 GO:0034330 BP e cell junction organization 6/100 407/19669 0.017699938207399 4 6 0.1274097516425963 60, 351, 4137, 5663, 6622, 9971 GO:0001523 BP e retinoid metabolic process 3/100 108/19669 0.0177189351107988 8 3 0.1274868683287493 335, 348, 7276 GO:1901800 BP e positive regulation of proteasomal protein catabolic process 3/100 109/19669 0.0181545696271015 10 3 0.1304992183844435 4780, 5071, 5663 GO:0001764 BP e neuron migration 3/100 109/19669 0.0181545696271015 5 3 0.1304992183844435 581, 5663, 7422 GO:0033003 BP e regulation of mast cell activation 2/100 41/19669 0.0184483526542674 6 2 0.1319331539726654 3162, 26762 GO:0045616 BP e regulation of keratinocyte differentiation 2/100 41/19669 0.0184483526542674 7 2 0.1319331539726654 4831, 4851 GO:0048592 BP e eye morphogenesis 2/100 41/19669 0.0184483526542674 5 2 0.1319331539726654 581, 7422 GO:0002200 BP e somatic diversification of immune receptors 2/100 41/19669 0.0184483526542674 2 2 0.1319331539726654 3146, 5591 GO:1900026 BP e positive regulation of substrate adhesion-dependent cell spreading 2/100 41/19669 0.0184483526542674 8 2 0.1319331539726654 335, 2243 GO:0003151 BP e outflow tract morphogenesis 2/100 41/19669 0.0184483526542674 3 2 0.1319331539726654 4851, 7422 GO:0010712 BP e regulation of collagen metabolic process 2/100 41/19669 0.0184483526542674 4 2 0.1319331539726654 3569, 5468 GO:0046596 BP e regulation of viral entry into host cell 2/100 41/19669 0.0184483526542674 6 2 0.1319331539726654 2934, 3440 GO:0006911 BP e phagocytosis, engulfment 2/100 41/19669 0.0184483526542674 7 2 0.1319331539726654 2934, 26762 GO:0045687 BP e positive regulation of glial cell differentiation 2/100 41/19669 0.0184483526542674 9 2 0.1319331539726654 4851, 5468 GO:0006757 BP e ATP generation from ADP 2/100 41/19669 0.0184483526542674 11 2 0.1319331539726654 229, 2023 GO:0044242 BP e cellular lipid catabolic process 4/100 198/19669 0.0184660630947537 5 4 0.1319984723772691 3030, 9370, 26061, 83667 GO:2000736 BP e regulation of stem cell differentiation 3/100 111/19669 0.0190436694435722 5 3 0.1360641006205092 4780, 4851, 5591 GO:0010389 BP e regulation of G2/M transition of mitotic cell cycle 4/100 200/19669 0.0190835583849103 8 4 0.1362858299507058 351, 7846, 10383, 23476 GO:0061515 BP e myeloid cell development 2/100 42/19669 0.0193073875703792 4 2 0.1366584046643474 302, 351 GO:0106027 BP e neuron projection organization 2/100 42/19669 0.0193073875703792 6 2 0.1366584046643474 351, 5663 GO:0001756 BP e somitogenesis 2/100 42/19669 0.0193073875703792 5 2 0.1366584046643474 5591, 5663 GO:0035337 BP e fatty-acyl-CoA metabolic process 2/100 42/19669 0.0193073875703792 11 2 0.1366584046643474 2180, 2194 GO:0060999 BP e positive regulation of dendritic spine development 2/100 42/19669 0.0193073875703792 5 2 0.1366584046643474 348, 5663 GO:0098586 BP e cellular response to virus 2/100 42/19669 0.0193073875703792 6 2 0.1366584046643474 581, 3569 GO:0007507 BP e heart development 4/100 201/19669 0.0193970602505378 4 4 0.1366584046643474 4851, 5465, 5468, 5591 GO:0023052 BP e signaling 8/100 661/19669 0.019408662820377 1 8 0.1366584046643474 183, 348, 3440, 3553, 3627, 4137, 5071, 6622 GO:0035148 BP e tube formation 3/100 112/19669 0.0194971439511946 3 3 0.1366584046643474 4524, 4851, 7422 GO:0071456 BP e cellular response to hypoxia 3/100 112/19669 0.0194971439511946 6 3 0.1366584046643474 3162, 3654, 7422 GO:0031396 BP e regulation of protein ubiquitination 4/100 202/19669 0.0197137427913641 9 4 0.1366584046643474 3309, 5071, 5663, 9474 GO:0050807 BP e regulation of synapse organization 4/100 202/19669 0.0197137427913641 5 4 0.1366584046643474 348, 351, 6622, 7846 GO:0070925 BP e organelle assembly 7/100 538/19669 0.0198912084092879 5 7 0.1366584046643474 2934, 4137, 4851, 5663, 9474, 10096, 81631 GO:0034404 BP e nucleobase-containing small molecule biosynthetic process 3/100 113/19669 0.0199565733849692 6 3 0.1366584046643474 2876, 4831, 4860 GO:0002260 BP e lymphocyte homeostasis 2/100 43/19669 0.020182980673916 6 2 0.1366584046643474 581, 11035 GO:0043300 BP e regulation of leukocyte degranulation 2/100 43/19669 0.020182980673916 9 2 0.1366584046643474 3162, 729230 GO:0045540 BP e regulation of cholesterol biosynthetic process 2/100 43/19669 0.020182980673916 9 2 0.1366584046643474 348, 2194 GO:0021549 BP e cerebellum development 2/100 43/19669 0.020182980673916 3 2 0.1366584046643474 1152, 5663 GO:0030574 BP e collagen catabolic process 2/100 43/19669 0.020182980673916 3 2 0.1366584046643474 4313, 4318 GO:0045840 BP e positive regulation of mitotic nuclear division 2/100 43/19669 0.020182980673916 8 2 0.1366584046643474 3479, 3553 GO:0002548 BP e monocyte chemotaxis 2/100 43/19669 0.020182980673916 7 2 0.1366584046643474 3569, 6347 GO:0106118 BP e regulation of sterol biosynthetic process 2/100 43/19669 0.020182980673916 8 2 0.1366584046643474 348, 2194 GO:0042398 BP e cellular modified amino acid biosynthetic process 2/100 43/19669 0.020182980673916 5 2 0.1366584046643474 1152, 1719 GO:0002686 BP e negative regulation of leukocyte migration 2/100 43/19669 0.020182980673916 8 2 0.1366584046643474 3162, 6347 GO:0016101 BP e diterpenoid metabolic process 3/100 114/19669 0.0204219609434497 7 3 0.1381511995251391 335, 348, 7276 GO:0016236 BP e macroautophagy 3/100 114/19669 0.0204219609434497 5 3 0.1381511995251391 5071, 9474, 81631 GO:0050868 BP e negative regulation of T cell activation 3/100 115/19669 0.0208933092779948 8 3 0.1412156476892142 383, 3146, 3440 GO:0002761 BP e regulation of myeloid leukocyte differentiation 3/100 115/19669 0.0208933092779948 7 3 0.1412156476892142 3458, 4831, 9370 GO:0043124 BP e negative regulation of I-kappaB kinase/NF-kappaB signaling 2/100 44/19669 0.0210749449676816 8 2 0.1419445965219345 9370, 9971 GO:1903573 BP e negative regulation of response to endoplasmic reticulum stress 2/100 44/19669 0.0210749449676816 7 2 0.1419445965219345 3309, 5071 GO:0046622 BP e positive regulation of organ growth 2/100 44/19669 0.0210749449676816 6 2 0.1419445965219345 3479, 4851 GO:0048168 BP e regulation of neuronal synaptic plasticity 2/100 44/19669 0.0210749449676816 8 2 0.1419445965219345 348, 351 GO:0031057 BP e negative regulation of histone modification 2/100 44/19669 0.0210749449676816 9 2 0.1419445965219345 6622, 9474 GO:0070527 BP e platelet aggregation 2/100 44/19669 0.0210749449676816 5 2 0.1419445965219345 60, 2243 GO:0048747 BP e muscle fiber development 2/100 44/19669 0.0210749449676816 6 2 0.1419445965219345 2876, 7422 GO:1900271 BP e regulation of long-term synaptic potentiation 2/100 44/19669 0.0210749449676816 8 2 0.1419445965219345 348, 351 GO:0019439 BP e aromatic compound catabolic process 6/100 424/19669 0.0211680767168645 4 6 0.1425094928576317 2052, 2081, 2876, 3146, 3162, 4860 GO:0042752 BP e regulation of circadian rhythm 3/100 117/19669 0.0218538961713159 3 3 0.1469980166418498 5465, 5468, 5591 GO:0030534 BP e adult behavior 3/100 117/19669 0.0218538961713159 2 3 0.1469980166418498 351, 5071, 5465 GO:0045668 BP e negative regulation of osteoblast differentiation 2/100 45/19669 0.0219830948925297 6 2 0.1472876928149903 4851, 5468 GO:2000179 BP e positive regulation of neural precursor cell proliferation 2/100 45/19669 0.0219830948925297 6 2 0.1472876928149903 4851, 7422 GO:0035282 BP e segmentation 2/100 45/19669 0.0219830948925297 4 2 0.1472876928149903 5591, 5663 GO:0120009 BP e intermembrane lipid transfer 2/100 45/19669 0.0219830948925297 8 2 0.1472876928149903 335, 348 GO:0002707 BP e negative regulation of lymphocyte mediated immunity 2/100 45/19669 0.0219830948925297 7 2 0.1472876928149903 383, 3440 GO:0055002 BP e striated muscle cell development 2/100 45/19669 0.0219830948925297 5 2 0.1472876928149903 2876, 7422 GO:0030900 BP e forebrain development 2/100 45/19669 0.0219830948925297 3 2 0.1472876928149903 351, 4851 GO:0045581 BP e negative regulation of T cell differentiation 2/100 45/19669 0.0219830948925297 9 2 0.1472876928149903 3146, 3440 GO:0032881 BP e regulation of polysaccharide metabolic process 2/100 45/19669 0.0219830948925297 6 2 0.1472876928149903 3146, 3479 GO:0002757 BP e immune response-activating signal transduction 5/100 315/19669 0.0223735975640411 7 5 0.1497736696435812 60, 581, 5580, 5663, 10096 GO:0002429 BP e immune response-activating cell surface receptor signaling pathway 5/100 315/19669 0.0223735975640411 8 5 0.1497736696435812 60, 581, 5580, 5663, 10096 GO:0019748 BP e secondary metabolic process 2/100 46/19669 0.0229072463204458 2 2 0.1530132469061033 1244, 4780 GO:0006195 BP e purine nucleotide catabolic process 2/100 46/19669 0.0229072463204458 9 2 0.1530132469061033 2876, 4860 GO:0034198 BP e cellular response to amino acid starvation 2/100 46/19669 0.0229072463204458 7 2 0.1530132469061033 4217, 83667 GO:0009409 BP e response to cold 2/100 46/19669 0.0229072463204458 4 2 0.1530132469061033 3627, 5468 GO:0019674 BP e NAD metabolic process 2/100 46/19669 0.0229072463204458 2 2 0.1530132469061033 229, 2023 GO:0010810 BP e regulation of cell-substrate adhesion 4/100 212/19669 0.0230572296230923 5 4 0.1539482706721873 335, 2243, 4851, 7422 GO:0036294 BP e cellular response to decreased oxygen levels 3/100 120/19669 0.023339517811428 5 3 0.1556979536705145 3162, 3654, 7422 GO:0051053 BP e negative regulation of DNA metabolic process 3/100 120/19669 0.023339517811428 7 3 0.1556979536705145 5468, 9104, 9370 GO:0043933 BP e protein-containing complex subunit organization 14/100 1512/19669 0.0237033055644683 4 14 0.1580562706400205 183, 213, 229, 335, 348, 2243, 2934, 4137, 4143, 5071, 5591, 6622, 9131, 81631 GO:0000041 BP e transition metal ion transport 3/100 121/19669 0.0238466566083813 6 3 0.1582616052535217 1244, 1356, 3934 GO:0010811 BP e positive regulation of cell-substrate adhesion 3/100 121/19669 0.0238466566083813 6 3 0.1582616052535217 335, 2243, 7422 GO:0042177 BP e negative regulation of protein catabolic process 3/100 121/19669 0.0238466566083813 7 3 0.1582616052535217 302, 5663, 6622 GO:0045599 BP e negative regulation of fat cell differentiation 2/100 47/19669 0.0238472165420998 6 2 0.1582616052535217 3569, 9370 GO:0031279 BP e regulation of cyclase activity 2/100 47/19669 0.0238472165420998 4 2 0.1582616052535217 4846, 729230 GO:0031952 BP e regulation of protein autophosphorylation 2/100 47/19669 0.0238472165420998 9 2 0.1582616052535217 7422, 9370 GO:0002823 BP e negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/100 47/19669 0.0238472165420998 7 2 0.1582616052535217 383, 3440 GO:0051646 BP e mitochondrion localization 2/100 47/19669 0.0238472165420998 4 2 0.1582616052535217 213, 4137 GO:1900015 BP e regulation of cytokine production involved in inflammatory response 2/100 47/19669 0.0238472165420998 7 2 0.1582616052535217 3569, 5465 GO:0120163 BP e negative regulation of cold-induced thermogenesis 2/100 47/19669 0.0238472165420998 5 2 0.1582616052535217 4851, 9370 GO:0002762 BP e negative regulation of myeloid leukocyte differentiation 2/100 47/19669 0.0238472165420998 8 2 0.1582616052535217 4831, 9370 GO:1902749 BP e regulation of cell cycle G2/M phase transition 4/100 216/19669 0.0244855696221625 7 4 0.1599115782949133 351, 7846, 10383, 23476 GO:0006820 BP e anion transport 19/100 2223/19669 0.024737520594037 5 19 0.1599115782949133 335, 348, 350, 581, 821, 847, 1244, 2180, 3309, 3569, 5071, 5243, 5468, 5663, 6622, 9131, 9971, 26061, 83667 GO:0046031 BP e ADP metabolic process 2/100 48/19669 0.0248028242599885 10 2 0.1599115782949133 229, 2023 GO:0019233 BP e sensory perception of pain 2/100 48/19669 0.0248028242599885 5 2 0.1599115782949133 6347, 729230 GO:0060688 BP e regulation of morphogenesis of a branching structure 2/100 48/19669 0.0248028242599885 5 2 0.1599115782949133 183, 7422 GO:1903428 BP e positive regulation of reactive oxygen species biosynthetic process 2/100 48/19669 0.0248028242599885 7 2 0.1599115782949133 3458, 3553 GO:0046638 BP e positive regulation of alpha-beta T cell differentiation 2/100 48/19669 0.0248028242599885 10 2 0.1599115782949133 3458, 4860 GO:0052372 BP e modulation by symbiont of entry into host 2/100 48/19669 0.0248028242599885 4 2 0.1599115782949133 2934, 3440 GO:0007018 BP e microtubule-based movement 5/100 324/19669 0.0248875587407266 3 5 0.1599115782949133 351, 3064, 4137, 6652, 10096 GO:0046887 BP e positive regulation of hormone secretion 3/100 124/19669 0.0254038538659904 8 3 0.1612893197184787 2243, 6696, 9971 GO:0002705 BP e positive regulation of leukocyte mediated immunity 3/100 124/19669 0.0254038538659904 6 3 0.1612893197184787 383, 3553, 3569 GO:2001020 BP e regulation of response to DNA damage stimulus 4/100 219/19669 0.0255913155272506 6 4 0.1624125137997476 3146, 4137, 5580, 5591 GO:0030514 BP e negative regulation of BMP signaling pathway 2/100 49/19669 0.0257738895811364 8 2 0.163033358262922 4851, 5468 GO:0003179 BP e heart valve morphogenesis 2/100 49/19669 0.0257738895811364 3 2 0.163033358262922 4846, 4851 GO:0065002 BP e intracellular protein transmembrane transport 2/100 49/19669 0.0257738895811364 10 2 0.163033358262922 3309, 9131 GO:0009066 BP e aspartate family amino acid metabolic process 2/100 49/19669 0.0257738895811364 8 2 0.163033358262922 4143, 4524 GO:0019935 BP e cyclic-nucleotide-mediated signaling 2/100 49/19669 0.0257738895811364 7 2 0.163033358262922 196, 348 GO:0051339 BP e regulation of lyase activity 2/100 49/19669 0.0257738895811364 4 2 0.163033358262922 4846, 729230 GO:1990928 BP e response to amino acid starvation 2/100 49/19669 0.0257738895811364 6 2 0.163033358262922 4217, 83667 GO:0021782 BP e glial cell development 2/100 49/19669 0.0257738895811364 4 2 0.163033358262922 351, 2934 GO:0097435 BP e supramolecular fiber organization 6/100 445/19669 0.0260563327120628 4 6 0.164752243401252 351, 2934, 4137, 6622, 10096, 11035 GO:0006139 BP e nucleobase-containing compound metabolic process 21/100 2599/19669 0.0261767451857954 4 21 0.1654456297369164 229, 351, 581, 1737, 2023, 2081, 2180, 2194, 2876, 3146, 4137, 4199, 4831, 4851, 4860, 5465, 5468, 5591, 7276, 9971, 83667 GO:0032479 BP e regulation of type I interferon production 3/100 126/19669 0.026471781820416 7 3 0.1671044799902392 3146, 3654, 5591 GO:0050806 BP e positive regulation of synaptic transmission 3/100 126/19669 0.026471781820416 7 3 0.1671044799902392 351, 6347, 729230 GO:0019730 BP e antimicrobial humoral response 3/100 126/19669 0.026471781820416 5 3 0.1671044799902392 2243, 3627, 3934 GO:0007155 BP e cell adhesion 10/100 918/19669 0.026587195057467 2 10 0.1677642197353089 60, 302, 351, 2243, 3553, 4831, 5663, 6347, 6696, 7450 GO:0031113 BP e regulation of microtubule polymerization 2/100 50/19669 0.0267602340028999 9 2 0.1683728541719666 4137, 6622 GO:0090596 BP e sensory organ morphogenesis 2/100 50/19669 0.0267602340028999 4 2 0.1683728541719666 581, 7422 GO:0099024 BP e plasma membrane invagination 2/100 50/19669 0.0267602340028999 6 2 0.1683728541719666 2934, 26762 GO:0043370 BP e regulation of CD4-positive, alpha-beta T cell differentiation 2/100 50/19669 0.0267602340028999 10 2 0.1683728541719666 3146, 3458 GO:0007254 BP e JNK cascade 2/100 50/19669 0.0267602340028999 8 2 0.1683728541719666 3654, 4217 GO:0006956 BP e complement activation 2/100 50/19669 0.0267602340028999 7 2 0.1683728541719666 1401, 3075 GO:0046631 BP e alpha-beta T cell activation 2/100 50/19669 0.0267602340028999 6 2 0.1683728541719666 3146, 3569 GO:0045598 BP e regulation of fat cell differentiation 3/100 127/19669 0.0270146759500083 5 3 0.1697655626258183 3569, 5468, 9370 GO:0009755 BP e hormone-mediated signaling pathway 3/100 127/19669 0.0270146759500083 5 3 0.1697655626258183 2180, 5465, 5468 GO:0034754 BP e cellular hormone metabolic process 3/100 127/19669 0.0270146759500083 5 3 0.1697655626258183 1559, 6696, 7276 GO:0022610 BP e biological adhesion 10/100 924/19669 0.0270818408362397 1 10 0.1701181757019307 60, 302, 351, 2243, 3553, 4831, 5663, 6347, 6696, 7450 GO:0008610 BP e lipid biosynthetic process 7/100 574/19669 0.0271163801541714 4 7 0.1702656428285184 335, 1559, 1571, 2180, 2194, 2944, 5130 GO:0015748 BP e organophosphate ester transport 3/100 128/19669 0.0275635185238215 7 3 0.1729321443463572 335, 348, 5243 GO:0050714 BP e positive regulation of protein secretion 3/100 128/19669 0.0275635185238215 10 3 0.1729321443463572 2243, 3479, 9971 GO:0019320 BP e hexose catabolic process 2/100 51/19669 0.0277616804071664 6 2 0.1737504113323676 229, 2023 GO:0048260 BP e positive regulation of receptor-mediated endocytosis 2/100 51/19669 0.0277616804071664 8 2 0.1737504113323676 302, 7422 GO:0043525 BP e positive regulation of neuron apoptotic process 2/100 51/19669 0.0277616804071664 8 2 0.1737504113323676 581, 2896 GO:1902893 BP e regulation of pri-miRNA transcription by RNA polymerase II 2/100 51/19669 0.0277616804071664 11 2 0.1737504113323676 5465, 5468 GO:0002711 BP e positive regulation of T cell mediated immunity 2/100 51/19669 0.0277616804071664 8 2 0.1737504113323676 3553, 3569 GO:0000186 BP e activation of MAPKK activity 2/100 51/19669 0.0277616804071664 12 2 0.1737504113323676 4217, 5663 GO:0048469 BP e cell maturation 3/100 129/19669 0.0281183052286932 4 3 0.1759108607599957 351, 5468, 7422 GO:0007612 BP e learning 3/100 130/19669 0.0286790313014472 6 3 0.1792730673148959 351, 3064, 5071 GO:0010977 BP e negative regulation of neuron projection development 3/100 130/19669 0.0286790313014472 8 3 0.1792730673148959 348, 5663, 6696 GO:0072523 BP e purine-containing compound catabolic process 2/100 52/19669 0.0287780530487651 5 2 0.1793094074576905 2876, 4860 GO:0051496 BP e positive regulation of stress fiber assembly 2/100 52/19669 0.0287780530487651 11 2 0.1793094074576905 335, 50507 GO:0140115 BP e export across plasma membrane 2/100 52/19669 0.0287780530487651 5 2 0.1793094074576905 1244, 5243 GO:0030858 BP e positive regulation of epithelial cell differentiation 2/100 52/19669 0.0287780530487651 6 2 0.1793094074576905 4831, 4851 GO:0002820 BP e negative regulation of adaptive immune response 2/100 52/19669 0.0287780530487651 6 2 0.1793094074576905 383, 3440 GO:0030449 BP e regulation of complement activation 2/100 52/19669 0.0287780530487651 6 2 0.1793094074576905 3075, 3553 GO:0050433 BP e regulation of catecholamine secretion 2/100 52/19669 0.0287780530487651 8 2 0.1793094074576905 5071, 6622 GO:0043392 BP e negative regulation of DNA binding 2/100 52/19669 0.0287780530487651 5 2 0.1793094074576905 3162, 5663 GO:0034032 BP e purine nucleoside bisphosphate metabolic process 3/100 131/19669 0.0292456915375893 8 3 0.181094169247881 1737, 2180, 2194 GO:0033865 BP e nucleoside bisphosphate metabolic process 3/100 131/19669 0.0292456915375893 7 3 0.181094169247881 1737, 2180, 2194 GO:0033875 BP e ribonucleoside bisphosphate metabolic process 3/100 131/19669 0.0292456915375893 8 3 0.181094169247881 1737, 2180, 2194 GO:0070228 BP e regulation of lymphocyte apoptotic process 2/100 53/19669 0.0298091775491543 8 2 0.181094169247881 581, 11035 GO:0072073 BP e kidney epithelium development 2/100 53/19669 0.0298091775491543 5 2 0.181094169247881 847, 4851 GO:0002720 BP e positive regulation of cytokine production involved in immune response 2/100 53/19669 0.0298091775491543 8 2 0.181094169247881 3553, 3569 GO:0045620 BP e negative regulation of lymphocyte differentiation 2/100 53/19669 0.0298091775491543 8 2 0.181094169247881 3146, 3440 GO:0051653 BP e spindle localization 2/100 53/19669 0.0298091775491543 4 2 0.181094169247881 3064, 10096 GO:0050732 BP e negative regulation of peptidyl-tyrosine phosphorylation 2/100 53/19669 0.0298091775491543 10 2 0.181094169247881 5580, 5663 GO:0032434 BP e regulation of proteasomal ubiquitin-dependent protein catabolic process 3/100 132/19669 0.029818280299307 10 3 0.181094169247881 4780, 5071, 5663 GO:0006518 BP e peptide metabolic process 5/100 341/19669 0.0301178837670566 5 5 0.181094169247881 2876, 2941, 2944, 2947, 5663 GO:0048729 BP e tissue morphogenesis 5/100 341/19669 0.0301178837670566 3 5 0.181094169247881 60, 4846, 4851, 5663, 7422 GO:0000086 BP e G2/M transition of mitotic cell cycle 3/100 133/19669 0.0303967915144156 5 3 0.1825943096826139 5243, 7846, 10383 GO:0051147 BP e regulation of muscle cell differentiation 3/100 133/19669 0.0303967915144156 5 3 0.1825943096826139 3479, 4851, 5465 GO:0000165 BP e MAPK cascade 5/100 343/19669 0.0307754499713913 6 5 0.1847967908933724 3479, 3553, 3654, 4217, 6347 GO:0051148 BP e negative regulation of muscle cell differentiation 2/100 54/19669 0.0308548808848184 6 2 0.1849850474551443 4851, 5465 GO:0030834 BP e regulation of actin filament depolymerization 2/100 54/19669 0.0308548808848184 10 2 0.1849850474551443 2934, 136319 GO:0001776 BP e leukocyte homeostasis 2/100 54/19669 0.0308548808848184 5 2 0.1849850474551443 581, 11035 GO:0071560 BP e cellular response to transforming growth factor beta stimulus 2/100 54/19669 0.0308548808848184 6 2 0.1849850474551443 383, 50507 GO:0006811 BP e ion transport 22/100 2805/19669 0.0314256643746364 4 22 0.1883337128993981 302, 335, 348, 350, 581, 821, 847, 1244, 1356, 2180, 3309, 3569, 3934, 5071, 5243, 5468, 5663, 6622, 9131, 9971, 26061, 83667 GO:1903320 BP e regulation of protein modification by small protein conjugation or removal 4/100 234/19669 0.0315686973054312 8 4 0.1889872540052706 3309, 5071, 5663, 9474 GO:0044839 BP e cell cycle G2/M phase transition 3/100 135/19669 0.0315715549088727 4 3 0.1889872540052706 5243, 7846, 10383 GO:1903305 BP e regulation of regulated secretory pathway 3/100 135/19669 0.0315715549088727 8 3 0.1889872540052706 3162, 4851, 729230 GO:0071385 BP e cellular response to glucocorticoid stimulus 2/100 55/19669 0.0319149913756998 8 2 0.1904504526064448 383, 1244 GO:0046164 BP e alcohol catabolic process 2/100 55/19669 0.0319149913756998 5 2 0.1904504526064448 348, 6652 GO:0071333 BP e cellular response to glucose stimulus 2/100 55/19669 0.0319149913756998 8 2 0.1904504526064448 2081, 4831 GO:0097035 BP e regulation of membrane lipid distribution 2/100 55/19669 0.0319149913756998 5 2 0.1904504526064448 5243, 5580 GO:0032653 BP e regulation of interleukin-10 production 2/100 55/19669 0.0319149913756998 7 2 0.1904504526064448 3146, 3569 GO:0045747 BP e positive regulation of Notch signaling pathway 2/100 55/19669 0.0319149913756998 7 2 0.1904504526064448 4846, 4851 GO:0043030 BP e regulation of macrophage activation 2/100 55/19669 0.0319149913756998 6 2 0.1904504526064448 2896, 3569 GO:2000242 BP e negative regulation of reproductive process 2/100 55/19669 0.0319149913756998 4 2 0.1904504526064448 3479, 9104 GO:0002768 BP e immune response-regulating cell surface receptor signaling pathway 5/100 349/19669 0.0328023129738499 6 5 0.1956696111114538 60, 581, 5580, 5663, 10096 GO:0036498 BP e IRE1-mediated unfolded protein response 2/100 56/19669 0.0329893386848038 6 2 0.1965566869373328 2081, 3309 GO:0006081 BP e cellular aldehyde metabolic process 2/100 56/19669 0.0329893386848038 3 2 0.1965566869373328 229, 6888 GO:0030301 BP e cholesterol transport 2/100 56/19669 0.0329893386848038 9 2 0.1965566869373328 335, 348 GO:0002764 BP e immune response-regulating signaling pathway 5/100 352/19669 0.033846392152306 5 5 0.200711372723771 60, 581, 5580, 5663, 10096 GO:0007623 BP e circadian rhythm 3/100 139/19669 0.0339918377005583 2 3 0.200711372723771 196, 5465, 9370 GO:2001244 BP e positive regulation of intrinsic apoptotic signaling pathway 2/100 57/19669 0.0340777538036996 9 2 0.200711372723771 581, 11035 GO:0046128 BP e purine ribonucleoside metabolic process 2/100 57/19669 0.0340777538036996 8 2 0.200711372723771 4831, 4860 GO:0046365 BP e monosaccharide catabolic process 2/100 57/19669 0.0340777538036996 5 2 0.200711372723771 229, 2023 GO:0072431 BP e signal transduction involved in mitotic G1 DNA damage checkpoint 2/100 57/19669 0.0340777538036996 10 2 0.200711372723771 581, 5591 GO:0051785 BP e positive regulation of nuclear division 2/100 57/19669 0.0340777538036996 7 2 0.200711372723771 3479, 3553 GO:1900024 BP e regulation of substrate adhesion-dependent cell spreading 2/100 57/19669 0.0340777538036996 7 2 0.200711372723771 335, 2243 GO:0032781 BP e positive regulation of ATPase activity 2/100 57/19669 0.0340777538036996 6 2 0.200711372723771 229, 9104 GO:0010324 BP e membrane invagination 2/100 57/19669 0.0340777538036996 5 2 0.200711372723771 2934, 26762 GO:1902400 BP e intracellular signal transduction involved in G1 DNA damage checkpoint 2/100 57/19669 0.0340777538036996 9 2 0.200711372723771 581, 5591 GO:1902403 BP e signal transduction involved in mitotic DNA integrity checkpoint 2/100 57/19669 0.0340777538036996 8 2 0.200711372723771 581, 5591 GO:0071331 BP e cellular response to hexose stimulus 2/100 57/19669 0.0340777538036996 7 2 0.200711372723771 2081, 4831 GO:0030837 BP e negative regulation of actin filament polymerization 2/100 57/19669 0.0340777538036996 11 2 0.200711372723771 2934, 5580 GO:1902402 BP e signal transduction involved in mitotic DNA damage checkpoint 2/100 57/19669 0.0340777538036996 9 2 0.200711372723771 581, 5591 GO:0090092 BP e regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4/100 240/19669 0.0341711285812767 6 4 0.200711372723771 3309, 4851, 5465, 5468 GO:0048666 BP e neuron development 3/100 140/19669 0.0346116012410504 4 3 0.200711372723771 4137, 5663, 7422 GO:0007050 BP e cell cycle arrest 3/100 140/19669 0.0346116012410504 6 3 0.200711372723771 2081, 3458, 4851 GO:0035304 BP e regulation of protein dephosphorylation 3/100 140/19669 0.0346116012410504 8 3 0.200711372723771 3064, 5580, 9104 GO:0071326 BP e cellular response to monosaccharide stimulus 2/100 58/19669 0.0351800690394518 6 2 0.2011970503594066 2081, 4831 GO:0071806 BP e protein transmembrane transport 2/100 58/19669 0.0351800690394518 9 2 0.2011970503594066 3309, 9131 GO:0050922 BP e negative regulation of chemotaxis 2/100 58/19669 0.0351800690394518 6 2 0.2011970503594066 4851, 6347 GO:0030111 BP e regulation of Wnt signaling pathway 5/100 357/19669 0.0356322442189763 6 5 0.203707369439096 348, 351, 4851, 5071, 5663 GO:0045669 BP e positive regulation of osteoblast differentiation 2/100 59/19669 0.0362961180135385 6 2 0.2071180037924949 3479, 3569 GO:0072413 BP e signal transduction involved in mitotic cell cycle checkpoint 2/100 59/19669 0.0362961180135385 7 2 0.2071180037924949 581, 5591 GO:0034109 BP e homotypic cell-cell adhesion 2/100 59/19669 0.0362961180135385 4 2 0.2071180037924949 60, 2243 GO:1902017 BP e regulation of cilium assembly 2/100 59/19669 0.0362961180135385 8 2 0.2071180037924949 3064, 9474 GO:0032655 BP e regulation of interleukin-12 production 2/100 59/19669 0.0362961180135385 7 2 0.2071180037924949 3146, 3458 GO:0061919 BP e process utilizing autophagic mechanism 4/100 245/19669 0.036432871341225 2 4 0.2077443089816424 3146, 5071, 9474, 81631 GO:0006914 BP e autophagy 4/100 245/19669 0.036432871341225 4 4 0.2077443089816424 3146, 5071, 9474, 81631 GO:0071384 BP e cellular response to corticosteroid stimulus 2/100 60/19669 0.0374257356530804 7 2 0.212775054193169 383, 1244 GO:0071230 BP e cellular response to amino acid stimulus 2/100 60/19669 0.0374257356530804 6 2 0.212775054193169 4313, 83667 GO:0019229 BP e regulation of vasoconstriction 2/100 60/19669 0.0374257356530804 7 2 0.212775054193169 183, 2243 GO:0061098 BP e positive regulation of protein tyrosine kinase activity 2/100 60/19669 0.0374257356530804 11 2 0.212775054193169 183, 50507 GO:0046425 BP e regulation of receptor signaling pathway via JAK-STAT 2/100 60/19669 0.0374257356530804 7 2 0.212775054193169 3569, 4851 GO:0060998 BP e regulation of dendritic spine development 2/100 60/19669 0.0374257356530804 4 2 0.212775054193169 348, 5663 GO:0042278 BP e purine nucleoside metabolic process 2/100 60/19669 0.0374257356530804 7 2 0.212775054193169 4831, 4860 GO:0040014 BP e regulation of multicellular organism growth 2/100 60/19669 0.0374257356530804 5 2 0.212775054193169 351, 3479 GO:2000045 BP e regulation of G1/S transition of mitotic cell cycle 3/100 145/19669 0.0377981066358277 8 3 0.2148127256740725 581, 5591, 6347 GO:0045604 BP e regulation of epidermal cell differentiation 2/100 61/19669 0.0385687581683813 6 2 0.2187078806969007 4831, 4851 GO:0031060 BP e regulation of histone methylation 2/100 61/19669 0.0385687581683813 9 2 0.2187078806969007 4524, 23476 GO:1901570 BP e fatty acid derivative biosynthetic process 2/100 61/19669 0.0385687581683813 4 2 0.2187078806969007 2180, 2194 GO:0070613 BP e regulation of protein processing 2/100 61/19669 0.0385687581683813 7 2 0.2187078806969007 2023, 2934 GO:0009179 BP e purine ribonucleoside diphosphate metabolic process 2/100 61/19669 0.0385687581683813 9 2 0.2187078806969007 229, 2023 GO:0009135 BP e purine nucleoside diphosphate metabolic process 2/100 61/19669 0.0385687581683813 8 2 0.2187078806969007 229, 2023 GO:0015718 BP e monocarboxylic acid transport 3/100 147/19669 0.0391134336934949 9 3 0.220208036906855 1244, 5663, 9971 GO:0009952 BP e anterior/posterior pattern specification 3/100 147/19669 0.0391134336934949 4 3 0.220208036906855 4851, 5591, 5663 GO:0032233 BP e positive regulation of actin filament bundle assembly 2/100 62/19669 0.0397250230699007 10 2 0.220208036906855 335, 50507 GO:1905268 BP e negative regulation of chromatin organization 2/100 62/19669 0.0397250230699007 6 2 0.220208036906855 6622, 9474 GO:1901607 BP e alpha-amino acid biosynthetic process 2/100 62/19669 0.0397250230699007 8 2 0.220208036906855 1719, 4524 GO:0071559 BP e response to transforming growth factor beta 2/100 62/19669 0.0397250230699007 5 2 0.220208036906855 383, 50507 GO:0001947 BP e heart looping 2/100 62/19669 0.0397250230699007 7 2 0.220208036906855 4851, 5663 GO:0031343 BP e positive regulation of cell killing 2/100 62/19669 0.0397250230699007 5 2 0.220208036906855 383, 3458 GO:0007569 BP e cell aging 2/100 62/19669 0.0397250230699007 3 2 0.220208036906855 5580, 50507 GO:0008344 BP e adult locomotory behavior 2/100 62/19669 0.0397250230699007 3 2 0.220208036906855 351, 5071 GO:0002218 BP e activation of innate immune response 3/100 148/19669 0.0397797787662478 8 3 0.220208036906855 3146, 5580, 5591 GO:0010970 BP e transport along microtubule 3/100 149/19669 0.0404518954213945 6 3 0.2227387014437429 351, 3064, 4137 GO:0051250 BP e negative regulation of lymphocyte activation 3/100 149/19669 0.0404518954213945 7 3 0.2227387014437429 383, 3146, 3440 GO:0071479 BP e cellular response to ionizing radiation 2/100 63/19669 0.0408943691253493 6 2 0.224853283615265 3309, 50507 GO:0045665 BP e negative regulation of neuron differentiation 2/100 63/19669 0.0408943691253493 6 2 0.224853283615265 351, 4851 GO:1903317 BP e regulation of protein maturation 2/100 63/19669 0.0408943691253493 6 2 0.224853283615265 2023, 2934 GO:0001570 BP e vasculogenesis 2/100 63/19669 0.0408943691253493 4 2 0.224853283615265 4851, 7422 GO:0002793 BP e positive regulation of peptide secretion 3/100 150/19669 0.0411297711560723 9 3 0.2260668493185546 2243, 3479, 9971 GO:0030182 BP e neuron differentiation 4/100 256/19669 0.0417075945900881 4 4 0.2291609713464677 3309, 5663, 7422, 136319 GO:0032507 BP e maintenance of protein location in cell 2/100 64/19669 0.042076636390235 5 2 0.2308589782694178 2934, 3309 GO:0009185 BP e ribonucleoside diphosphate metabolic process 2/100 64/19669 0.042076636390235 8 2 0.2308589782694178 229, 2023 GO:0071322 BP e cellular response to carbohydrate stimulus 2/100 64/19669 0.042076636390235 5 2 0.2308589782694178 2081, 4831 GO:0022617 BP e extracellular matrix disassembly 2/100 64/19669 0.042076636390235 6 2 0.2308589782694178 4313, 4318 GO:0035239 BP e tube morphogenesis 4/100 258/19669 0.0427108596517442 3 4 0.2342552138418904 348, 4851, 5663, 7422 GO:0007626 BP e locomotory behavior 3/100 153/19669 0.0431978228748773 2 3 0.2368416437635777 348, 351, 5071 GO:0008088 BP e axo-dendritic transport 2/100 65/19669 0.0432716661676948 7 2 0.2369089086875929 351, 4137 GO:1904892 BP e regulation of receptor signaling pathway via STAT 2/100 65/19669 0.0432716661676948 6 2 0.2369089086875929 3569, 4851 GO:0032729 BP e positive regulation of interferon-gamma production 2/100 65/19669 0.0432716661676948 8 2 0.2369089086875929 3553, 729230 GO:0071229 BP e cellular response to acid chemical 2/100 65/19669 0.0432716661676948 4 2 0.2369089086875929 4313, 83667 GO:0045787 BP e positive regulation of cell cycle 5/100 377/19669 0.0433537982262421 5 5 0.2372741659679466 351, 581, 3479, 3553, 23476 GO:0060337 BP e type I interferon signaling pathway 2/100 66/19669 0.0444793010113596 7 2 0.2408198220511809 3440, 3654 GO:0050771 BP e negative regulation of axonogenesis 2/100 66/19669 0.0444793010113596 9 2 0.2408198220511809 5663, 6696 GO:2000514 BP e regulation of CD4-positive, alpha-beta T cell activation 2/100 66/19669 0.0444793010113596 9 2 0.2408198220511809 3146, 3458 GO:0140029 BP e exocytic process 2/100 66/19669 0.0444793010113596 2 2 0.2408198220511809 5663, 6622 GO:0007187 BP e G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 2/100 66/19669 0.0444793010113596 6 2 0.2408198220511809 183, 6347 GO:0051640 BP e organelle localization 6/100 508/19669 0.0450591508822537 3 6 0.2418766418130048 213, 3064, 4137, 7846, 10096, 10383 GO:0050877 BP e nervous system process 9/100 882/19669 0.0455556946749393 3 9 0.2444568134753542 348, 351, 2876, 3064, 4137, 5071, 5663, 6347, 729230 GO:0032922 BP e circadian regulation of gene expression 2/100 67/19669 0.0456993847193839 6 2 0.2447159119106887 196, 5465 GO:0002637 BP e regulation of immunoglobulin production 2/100 67/19669 0.0456993847193839 7 2 0.2447159119106887 3569, 5591 GO:0072662 BP e protein localization to peroxisome 2/100 67/19669 0.0456993847193839 6 2 0.2447159119106887 847, 26061 GO:0006625 BP e protein targeting to peroxisome 2/100 67/19669 0.0456993847193839 11 2 0.2447159119106887 847, 26061 GO:0072663 BP e establishment of protein localization to peroxisome 2/100 67/19669 0.0456993847193839 7 2 0.2447159119106887 847, 26061 GO:0043507 BP e positive regulation of JUN kinase activity 2/100 67/19669 0.0456993847193839 13 2 0.2447159119106887 2081, 4217 GO:0009064 BP e glutamine family amino acid metabolic process 2/100 68/19669 0.0469317623323606 8 2 0.250878715628701 383, 4846 GO:0045682 BP e regulation of epidermis development 2/100 68/19669 0.0469317623323606 4 2 0.250878715628701 4831, 4851 GO:0002449 BP e lymphocyte mediated immunity 2/100 68/19669 0.0469317623323606 4 2 0.250878715628701 5580, 10383 GO:0050905 BP e neuromuscular process 2/100 68/19669 0.0469317623323606 4 2 0.250878715628701 351, 5071 GO:0003143 BP e embryonic heart tube morphogenesis 2/100 68/19669 0.0469317623323606 6 2 0.250878715628701 4851, 5663 GO:0072655 BP e establishment of protein localization to mitochondrion 2/100 69/19669 0.048176280100726 7 2 0.2574419967882548 581, 9131 GO:2000058 BP e regulation of ubiquitin-dependent protein catabolic process 3/100 161/19669 0.0489626069914482 9 3 0.2601019225938792 4780, 5071, 5663 GO:0060333 BP e interferon-gamma-mediated signaling pathway 2/100 70/19669 0.0494327854999324 7 2 0.2601019225938792 3458, 5580 GO:0033044 BP e regulation of chromosome organization 4/100 271/19669 0.0495636340254292 6 4 0.2601019225938792 3553, 4137, 7422, 23476 GO:1902806 BP e regulation of cell cycle G1/S phase transition 3/100 163/19669 0.0504599637754478 7 3 0.263962896840293 581, 5591, 6347 GO:0009119 BP e ribonucleoside metabolic process 2/100 71/19669 0.0507011272251925 7 2 0.2647744648780837 4831, 4860 GO:0072401 BP e signal transduction involved in DNA integrity checkpoint 2/100 71/19669 0.0507011272251925 7 2 0.2647744648780837 581, 5591 GO:0043574 BP e peroxisomal transport 2/100 71/19669 0.0507011272251925 5 2 0.2647744648780837 847, 26061 GO:0072422 BP e signal transduction involved in DNA damage checkpoint 2/100 71/19669 0.0507011272251925 8 2 0.2647744648780837 581, 5591 GO:0001708 BP e cell fate specification 2/100 71/19669 0.0507011272251925 3 2 0.2647744648780837 4851, 5663 GO:2001252 BP e positive regulation of chromosome organization 3/100 164/19669 0.0512169779426767 7 3 0.2673776426518982 3553, 7422, 23476 GO:0048534 BP e hematopoietic or lymphoid organ development 3/100 165/19669 0.0519795267907155 4 3 0.2706326041413051 5591, 5663, 11035 GO:0006826 BP e iron ion transport 2/100 72/19669 0.0519811551554059 7 2 0.2706326041413051 1356, 3934 GO:0060193 BP e positive regulation of lipase activity 2/100 72/19669 0.0519811551554059 6 2 0.2706326041413051 335, 350 GO:0015918 BP e sterol transport 2/100 72/19669 0.0519811551554059 8 2 0.2706326041413051 335, 348 GO:0009166 BP e nucleotide catabolic process 2/100 72/19669 0.0519811551554059 8 2 0.2706326041413051 2876, 4860 GO:0018107 BP e peptidyl-threonine phosphorylation 2/100 72/19669 0.0519811551554059 9 2 0.2706326041413051 5580, 5591 GO:1903747 BP e regulation of establishment of protein localization to mitochondrion 2/100 72/19669 0.0519811551554059 6 2 0.2706326041413051 4137, 5071 GO:0002009 BP e morphogenesis of an epithelium 4/100 276/19669 0.0523519866454663 4 4 0.2724711107452576 60, 4851, 5663, 7422 GO:0035113 BP e embryonic appendage morphogenesis 2/100 73/19669 0.0532727203694326 4 2 0.2769821508397191 4851, 5663 GO:0008652 BP e cellular amino acid biosynthetic process 2/100 73/19669 0.0532727203694326 7 2 0.2769821508397191 1719, 4524 GO:0030326 BP e embryonic limb morphogenesis 2/100 73/19669 0.0532727203694326 5 2 0.2769821508397191 4851, 5663 GO:0072395 BP e signal transduction involved in cell cycle checkpoint 2/100 74/19669 0.0545756751335544 6 2 0.2776593852249264 581, 5591 GO:0051403 BP e stress-activated MAPK cascade 2/100 74/19669 0.0545756751335544 7 2 0.2776593852249264 3654, 4217 GO:0071260 BP e cellular response to mechanical stimulus 2/100 74/19669 0.0545756751335544 5 2 0.2776593852249264 3553, 136319 GO:0045739 BP e positive regulation of DNA repair 2/100 74/19669 0.0545756751335544 8 2 0.2776593852249264 3146, 5591 GO:0006970 BP e response to osmotic stress 2/100 74/19669 0.0545756751335544 3 2 0.2776593852249264 581, 6652 GO:1902036 BP e regulation of hematopoietic stem cell differentiation 2/100 74/19669 0.0545756751335544 6 2 0.2776593852249264 4780, 5591 GO:0072384 BP e organelle transport along microtubule 2/100 74/19669 0.0545756751335544 7 2 0.2776593852249264 3064, 4137 GO:0060828 BP e regulation of canonical Wnt signaling pathway 4/100 280/19669 0.0546434805563167 7 4 0.2779124804235673 348, 4851, 5071, 5663 GO:0038093 BP e Fc receptor signaling pathway 3/100 169/19669 0.0550847212012097 7 3 0.2799715519440615 60, 5580, 10096 GO:1901617 BP e organic hydroxy compound biosynthetic process 3/100 169/19669 0.0550847212012097 4 3 0.2799715519440615 335, 1719, 6622 GO:0051302 BP e regulation of cell division 3/100 170/19669 0.0558746804293121 4 3 0.2836890316158607 847, 3553, 7422 GO:0071383 BP e cellular response to steroid hormone stimulus 2/100 75/19669 0.0558898728953404 6 2 0.2836890316158607 383, 1244 GO:0032410 BP e negative regulation of transporter activity 2/100 75/19669 0.0558898728953404 6 2 0.2836890316158607 4318, 6622 GO:0002920 BP e regulation of humoral immune response 2/100 75/19669 0.0558898728953404 5 2 0.2836890316158607 3075, 3553 GO:0044270 BP e cellular nitrogen compound catabolic process 5/100 408/19669 0.057178573935512 4 5 0.2897471008508711 2081, 2876, 3146, 3162, 4860 GO:0006835 BP e dicarboxylic acid transport 2/100 76/19669 0.0572151682576866 9 2 0.2897471008508711 1244, 5663 GO:0006303 BP e double-strand break repair via nonhomologous end joining 2/100 76/19669 0.0572151682576866 9 2 0.2897471008508711 3146, 5591 GO:2000177 BP e regulation of neural precursor cell proliferation 2/100 76/19669 0.0572151682576866 5 2 0.2897471008508711 4851, 7422 GO:0033238 BP e regulation of cellular amine metabolic process 2/100 76/19669 0.0572151682576866 5 2 0.2897471008508711 5071, 9971 GO:0002244 BP e hematopoietic progenitor cell differentiation 2/100 76/19669 0.0572151682576866 4 2 0.2897471008508711 5591, 5663 GO:1901616 BP e organic hydroxy compound catabolic process 2/100 76/19669 0.0572151682576866 4 2 0.2897471008508711 348, 6652 GO:0030330 BP e DNA damage response, signal transduction by p53 class mediator 2/100 77/19669 0.0585514170007986 7 2 0.2951122210194456 581, 83667 GO:1903363 BP e negative regulation of cellular protein catabolic process 2/100 77/19669 0.0585514170007986 8 2 0.2951122210194456 302, 5663 GO:0031397 BP e negative regulation of protein ubiquitination 2/100 77/19669 0.0585514170007986 10 2 0.2951122210194456 5663, 9474 GO:0007031 BP e peroxisome organization 2/100 77/19669 0.0585514170007986 5 2 0.2951122210194456 847, 26061 GO:0030593 BP e neutrophil chemotaxis 2/100 77/19669 0.0585514170007986 9 2 0.2951122210194456 3627, 6347 GO:0048015 BP e phosphatidylinositol-mediated signaling 2/100 78/19669 0.0598984760404211 7 2 0.2973669504071231 2934, 3479 GO:0001910 BP e regulation of leukocyte mediated cytotoxicity 2/100 78/19669 0.0598984760404211 6 2 0.2973669504071231 383, 11035 GO:0071347 BP e cellular response to interleukin-1 2/100 78/19669 0.0598984760404211 6 2 0.2973669504071231 1244, 6347 GO:0000726 BP e non-recombinational repair 2/100 78/19669 0.0598984760404211 8 2 0.2973669504071231 3146, 5591 GO:0050772 BP e positive regulation of axonogenesis 2/100 78/19669 0.0598984760404211 9 2 0.2973669504071231 4137, 7422 GO:0090090 BP e negative regulation of canonical Wnt signaling pathway 3/100 176/19669 0.0607277575021757 8 3 0.3013867100801307 348, 4851, 5071 GO:0006508 BP e proteolysis 11/100 1238/19669 0.0610813712520374 5 11 0.3030439405444413 60, 350, 1510, 2243, 3309, 4313, 4318, 4780, 5071, 5327, 5663 GO:2000106 BP e regulation of leukocyte apoptotic process 2/100 79/19669 0.0612562034548363 7 2 0.303617704080493 581, 11035 GO:1901992 BP e positive regulation of mitotic cell cycle phase transition 2/100 79/19669 0.0612562034548363 8 2 0.303617704080493 351, 23476 GO:0099003 BP e vesicle-mediated transport in synapse 2/100 79/19669 0.0612562034548363 5 2 0.303617704080493 821, 6622 GO:0045786 BP e negative regulation of cell cycle 6/100 551/19669 0.0620166456339422 5 6 0.3072878867695979 581, 2081, 3458, 4851, 5591, 6347 GO:0030512 BP e negative regulation of transforming growth factor beta receptor signaling pathway 2/100 80/19669 0.062624458449734 8 2 0.3100998763003239 3309, 5465 GO:0043462 BP e regulation of ATPase activity 2/100 80/19669 0.062624458449734 5 2 0.3100998763003239 229, 9104 GO:0018105 BP e peptidyl-serine phosphorylation 3/100 179/19669 0.0632262758427036 9 3 0.3120513734570717 2081, 5580, 5591 GO:0018210 BP e peptidyl-threonine modification 2/100 81/19669 0.0640031013596308 8 2 0.3120513734570717 5580, 5591 GO:1901568 BP e fatty acid derivative metabolic process 2/100 81/19669 0.0640031013596308 3 2 0.3120513734570717 2180, 2194 GO:0032945 BP e negative regulation of mononuclear cell proliferation 2/100 81/19669 0.0640031013596308 7 2 0.3120513734570717 383, 1401 GO:0010507 BP e negative regulation of autophagy 2/100 81/19669 0.0640031013596308 7 2 0.3120513734570717 3162, 6622 GO:0099111 BP e microtubule-based transport 3/100 181/19669 0.0649182478293143 4 3 0.3157685948461275 351, 3064, 4137 GO:0042391 BP e regulation of membrane potential 5/100 424/19669 0.0652036079508996 3 5 0.3170564064342325 351, 581, 4137, 5071, 5663 GO:0071621 BP e granulocyte chemotaxis 2/100 82/19669 0.0653919936577142 8 2 0.3172707384590862 3627, 6347 GO:0043506 BP e regulation of JUN kinase activity 2/100 82/19669 0.0653919936577142 12 2 0.3172707384590862 2081, 4217 GO:0031110 BP e regulation of microtubule polymerization or depolymerization 2/100 82/19669 0.0653919936577142 8 2 0.3172707384590862 4137, 6622 GO:0045069 BP e regulation of viral genome replication 2/100 82/19669 0.0653919936577142 6 2 0.3172707384590862 4851, 5465 GO:1901292 BP e nucleoside phosphate catabolic process 2/100 82/19669 0.0653919936577142 7 2 0.3172707384590862 2876, 4860 GO:0048017 BP e inositol lipid-mediated signaling 2/100 82/19669 0.0653919936577142 6 2 0.3172707384590862 2934, 3479 GO:1901019 BP e regulation of calcium ion transmembrane transporter activity 2/100 82/19669 0.0653919936577142 9 2 0.3172707384590862 3064, 9104 GO:0034622 BP e cellular protein-containing complex assembly 8/100 796/19669 0.0656849092766572 6 8 0.3185914761322897 229, 2243, 2934, 4137, 5071, 5591, 6622, 9131 GO:0046470 BP e phosphatidylcholine metabolic process 2/100 83/19669 0.0667909979095039 7 2 0.3236503330690385 335, 5130 GO:0051262 BP e protein tetramerization 2/100 83/19669 0.0667909979095039 7 2 0.3236503330690385 4143, 6622 GO:0035023 BP e regulation of Rho protein signal transduction 2/100 83/19669 0.0667909979095039 9 2 0.3236503330690385 335, 348 GO:0030163 BP e protein catabolic process 5/100 428/19669 0.0673043216065987 5 5 0.3260350990008043 302, 348, 3309, 4780, 5071 GO:0097306 BP e cellular response to alcohol 2/100 85/19669 0.0696187981172229 5 2 0.3320214759913421 196, 5468 GO:0021953 BP e central nervous system neuron differentiation 2/100 85/19669 0.0696187981172229 5 2 0.3320214759913421 5663, 136319 GO:0051492 BP e regulation of stress fiber assembly 2/100 85/19669 0.0696187981172229 10 2 0.3320214759913421 335, 50507 GO:1901879 BP e regulation of protein depolymerization 2/100 85/19669 0.0696187981172229 6 2 0.3320214759913421 2934, 136319 GO:0034308 BP e primary alcohol metabolic process 2/100 85/19669 0.0696187981172229 5 2 0.3320214759913421 3479, 7276 GO:1902115 BP e regulation of organelle assembly 3/100 187/19669 0.0701185389582571 6 3 0.3343012126913191 2934, 3064, 9474 GO:0036503 BP e ERAD pathway 2/100 86/19669 0.07104732473034 8 2 0.3385196060680907 3309, 5071 GO:0150104 BP e transport across blood-brain barrier 2/100 86/19669 0.07104732473034 6 2 0.3385196060680907 1244, 5243 GO:0070664 BP e negative regulation of leukocyte proliferation 2/100 87/19669 0.0724854246006633 6 2 0.3446248639494004 383, 1401 GO:0045582 BP e positive regulation of T cell differentiation 2/100 87/19669 0.0724854246006633 9 2 0.3446248639494004 3458, 4860 GO:0035108 BP e limb morphogenesis 2/100 87/19669 0.0724854246006633 4 2 0.3446248639494004 4851, 5663 GO:0010232 BP e vascular transport 2/100 87/19669 0.0724854246006633 5 2 0.3446248639494004 1244, 5243 GO:0048525 BP e negative regulation of viral process 2/100 87/19669 0.0724854246006633 5 2 0.3446248639494004 2934, 3440 GO:0035107 BP e appendage morphogenesis 2/100 87/19669 0.0724854246006633 3 2 0.3446248639494004 4851, 5663 GO:1990266 BP e neutrophil migration 2/100 87/19669 0.0724854246006633 8 2 0.3446248639494004 3627, 6347 GO:0042445 BP e hormone metabolic process 3/100 190/19669 0.0727875833469511 4 3 0.344856938092906 1559, 6696, 7276 GO:0040029 BP e regulation of gene expression, epigenetic 3/100 191/19669 0.0736873255193165 6 3 0.3450100212176091 60, 2876, 3146 GO:0097191 BP e extrinsic apoptotic signaling pathway 2/100 88/19669 0.0739329657677904 6 2 0.3459496330697156 581, 3458 GO:0030510 BP e regulation of BMP signaling pathway 2/100 88/19669 0.0739329657677904 7 2 0.3459496330697156 4851, 5468 GO:1903321 BP e negative regulation of protein modification by small protein conjugation or removal 2/100 89/19669 0.0753898173332788 9 2 0.3526593582854593 5663, 9474 GO:0098656 BP e anion transmembrane transport 5/100 443/19669 0.0755164327129367 6 5 0.3531443024770878 3309, 5243, 5663, 9131, 83667 GO:0071705 BP e nitrogen compound transport 14/100 1746/19669 0.0771484038848649 4 14 0.3606664446500823 348, 581, 821, 847, 1244, 3309, 3569, 5071, 5243, 5468, 5663, 6622, 9131, 26061 GO:0045638 BP e negative regulation of myeloid cell differentiation 2/100 91/19669 0.0783309334163243 7 2 0.3618663932929793 4831, 9370 GO:0031098 BP e stress-activated protein kinase signaling cascade 2/100 91/19669 0.0783309334163243 6 2 0.3618663932929793 3654, 4217 GO:0001654 BP e eye development 2/100 91/19669 0.0783309334163243 5 2 0.3618663932929793 3146, 7422 GO:0045833 BP e negative regulation of lipid metabolic process 2/100 91/19669 0.0783309334163243 6 2 0.3618663932929793 348, 3553 GO:0051056 BP e regulation of small GTPase mediated signal transduction 4/100 318/19669 0.0790622322887392 7 4 0.3650668331604251 335, 348, 3479, 4851 GO:0043279 BP e response to alkaloid 2/100 92/19669 0.0798149414328678 5 2 0.3683214238836089 3309, 5468 GO:0045185 BP e maintenance of protein location 2/100 92/19669 0.0798149414328678 4 2 0.3683214238836089 2934, 3309 GO:0070167 BP e regulation of biomineral tissue development 2/100 93/19669 0.0813077468325539 5 2 0.3748730448630931 4846, 4851 GO:0110020 BP e regulation of actomyosin structure organization 2/100 93/19669 0.0813077468325539 8 2 0.3748730448630931 335, 50507 GO:0007229 BP e integrin-mediated signaling pathway 2/100 93/19669 0.0813077468325539 6 2 0.3748730448630931 335, 4831 GO:0051963 BP e regulation of synapse assembly 2/100 94/19669 0.0828092239731196 6 2 0.379878816524546 351, 6622 GO:0018209 BP e peptidyl-serine modification 3/100 202/19669 0.0839089670177555 8 3 0.383761962081206 2081, 5580, 5591 GO:0090277 BP e positive regulation of peptide hormone secretion 2/100 95/19669 0.0843192482286918 10 2 0.3849520113436864 2243, 9971 GO:0097530 BP e granulocyte migration 2/100 95/19669 0.0843192482286918 7 2 0.3849520113436864 3627, 6347 GO:0110149 BP e regulation of biomineralization 2/100 95/19669 0.0843192482286918 3 2 0.3849520113436864 4846, 4851 GO:1901989 BP e positive regulation of cell cycle phase transition 2/100 95/19669 0.0843192482286918 7 2 0.3849520113436864 351, 23476 GO:0097711 BP e ciliary basal body-plasma membrane docking 2/100 95/19669 0.0843192482286918 5 2 0.3849520113436864 7846, 10383 GO:0070498 BP e interleukin-1-mediated signaling pathway 2/100 95/19669 0.0843192482286918 7 2 0.3849520113436864 3553, 3654 GO:0050830 BP e defense response to Gram-positive bacterium 2/100 96/19669 0.0858376959884713 7 2 0.3916519837718868 1401, 3569 GO:1901890 BP e positive regulation of cell junction assembly 2/100 96/19669 0.0858376959884713 6 2 0.3916519837718868 183, 7422 GO:0046165 BP e alcohol biosynthetic process 2/100 97/19669 0.0873644446753661 5 2 0.3955809700925346 335, 1719 GO:0051588 BP e regulation of neurotransmitter transport 2/100 98/19669 0.0888993726952073 5 2 0.4007502477385004 5071, 6622 GO:0006836 BP e neurotransmitter transport 2/100 98/19669 0.0888993726952073 4 2 0.4007502477385004 5071, 6622 GO:0043604 BP e amide biosynthetic process 4/100 332/19669 0.0892308520351489 5 4 0.4021267387469818 383, 1737, 2180, 2194 GO:1903076 BP e regulation of protein localization to plasma membrane 2/100 99/19669 0.0904423594676325 7 2 0.4072287630798316 60, 3458 GO:0002702 BP e positive regulation of production of molecular mediator of immune response 2/100 99/19669 0.0904423594676325 7 2 0.4072287630798316 3553, 3569 GO:0019886 BP e antigen processing and presentation of exogenous peptide antigen via MHC class II 2/100 99/19669 0.0904423594676325 5 2 0.4072287630798316 821, 1510 GO:0030178 BP e negative regulation of Wnt signaling pathway 3/100 209/19669 0.0907139717761075 7 3 0.4083322683925988 348, 4851, 5071 GO:0060560 BP e developmental growth involved in morphogenesis 2/100 100/19669 0.0919932853904139 3 2 0.410980459491791 351, 4851 GO:0048640 BP e negative regulation of developmental growth 2/100 100/19669 0.0919932853904139 5 2 0.410980459491791 5465, 6696 GO:0060562 BP e epithelial tube morphogenesis 2/100 101/19669 0.09355203187189 5 2 0.4158768834512961 4851, 5663 GO:0002495 BP e antigen processing and presentation of peptide antigen via MHC class II 2/100 101/19669 0.09355203187189 4 2 0.4158768834512961 821, 1510 GO:0003014 BP e renal system process 2/100 101/19669 0.09355203187189 3 2 0.4158768834512961 183, 2934 GO:0002504 BP e antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2/100 101/19669 0.09355203187189 3 2 0.4158768834512961 821, 1510 GO:0007017 BP e microtubule-based process 7/100 711/19669 0.0952765740788617 2 7 0.4234208706536765 351, 3064, 4137, 6652, 7846, 10096, 10383 GO:0009116 BP e nucleoside metabolic process 2/100 103/19669 0.0966925169462627 6 2 0.4266033791101036 4831, 4860 GO:0065003 BP e protein-containing complex assembly 11/100 1269/19669 0.0968976775771977 5 11 0.4266033791101036 229, 335, 348, 2243, 2934, 4137, 4143, 5071, 5591, 6622, 9131 GO:0006885 BP e regulation of pH 2/100 104/19669 0.0982740231804379 8 2 0.4321249190705541 2896, 5166 GO:0097549 BP e chromatin organization involved in negative regulation of transcription 2/100 104/19669 0.0982740231804379 6 2 0.4321249190705541 3146, 4524 GO:1901991 BP e negative regulation of mitotic cell cycle phase transition 3/100 217/19669 0.0987644617369885 8 3 0.4340334283644357 581, 5591, 6347 GO:0019882 BP e antigen processing and presentation 3/100 217/19669 0.0987644617369885 2 3 0.4340334283644357 821, 1510, 9474 GO:0008593 BP e regulation of Notch signaling pathway 2/100 105/19669 0.0998628852744821 6 2 0.4386101039880938 4846, 4851 GO:0030183 BP e B cell differentiation 2/100 105/19669 0.0998628852744821 7 2 0.4386101039880938 3440, 3569 GO:0007041 BP e lysosomal transport 2/100 106/19669 0.1014589894217996 5 2 0.4422718276503697 2896, 5071 GO:0120034 BP e positive regulation of plasma membrane bounded cell projection assembly 2/100 106/19669 0.1014589894217996 8 2 0.4422718276503697 3064, 10096 GO:0045931 BP e positive regulation of mitotic cell cycle 2/100 106/19669 0.1014589894217996 6 2 0.4422718276503697 351, 23476 GO:0051896 BP e regulation of protein kinase B signaling 3/100 221/19669 0.1028952192576782 7 3 0.4478386381152908 1440, 2876, 5465 GO:0045089 BP e positive regulation of innate immune response 3/100 221/19669 0.1028952192576782 7 3 0.4478386381152908 3146, 5580, 5591 GO:0001568 BP e blood vessel development 2/100 107/19669 0.1030622227977693 3 2 0.448311930146317 196, 5663 GO:0002708 BP e positive regulation of lymphocyte mediated immunity 2/100 107/19669 0.1030622227977693 7 2 0.448311930146317 3553, 3569 GO:0007517 BP e muscle organ development 2/100 108/19669 0.1046724735091599 4 2 0.4551877274105599 3479, 3627 GO:0060271 BP e cilium assembly 3/100 223/19669 0.1049862591248792 7 3 0.4564233129751108 2934, 4851, 10096 GO:0007088 BP e regulation of mitotic nuclear division 2/100 109/19669 0.106289630589969 7 2 0.4583349439001467 3479, 3553 GO:0034766 BP e negative regulation of ion transmembrane transport 2/100 110/19669 0.1079135840049762 7 2 0.4649468247022915 3553, 4318 GO:0007409 BP e axonogenesis 2/100 110/19669 0.1079135840049762 9 2 0.4649468247022915 60, 351 GO:0048754 BP e branching morphogenesis of an epithelial tube 2/100 110/19669 0.1079135840049762 6 2 0.4649468247022915 4851, 7422 GO:0034763 BP e negative regulation of transmembrane transport 2/100 111/19669 0.1095442246411146 6 2 0.4718403630637433 3553, 4318 GO:0009653 BP e anatomical structure morphogenesis 11/100 1351/19669 0.1098586196497591 2 11 0.4726363196703755 60, 348, 351, 581, 4313, 4846, 4851, 5663, 6347, 7422, 50507 GO:0032886 BP e regulation of microtubule-based process 3/100 228/19669 0.1102870384339455 4 3 0.4726363196703755 4137, 6622, 9104 GO:0045017 BP e glycerolipid biosynthetic process 3/100 228/19669 0.1102870384339455 6 3 0.4726363196703755 335, 2180, 5130 GO:0006974 BP e cellular response to DNA damage stimulus 7/100 757/19669 0.1104546484927315 4 7 0.4726363196703755 581, 3146, 3162, 5591, 5663, 23476, 83667 GO:1903828 BP e negative regulation of cellular protein localization 2/100 112/19669 0.1111814442940602 6 2 0.4746414501208288 4137, 9370 GO:1901988 BP e negative regulation of cell cycle phase transition 3/100 232/19669 0.1146012043121477 7 3 0.4891049734786341 581, 5591, 6347 GO:0003002 BP e regionalization 3/100 234/19669 0.1167822215510824 3 3 0.4959377454942489 4851, 5591, 5663 GO:0098609 BP e cell-cell adhesion 5/100 508/19669 0.1170170330260742 3 5 0.4967978312472502 60, 302, 2243, 3553, 5663 GO:0034401 BP e chromatin organization involved in regulation of transcription 2/100 116/19669 0.1177939805870555 5 2 0.4998206124165383 3146, 4524 GO:0019751 BP e polyol metabolic process 2/100 116/19669 0.1177939805870555 5 2 0.4998206124165383 1719, 6652 GO:0034655 BP e nucleobase-containing compound catabolic process 4/100 368/19669 0.118079875879748 5 4 0.5008956146056567 2081, 2876, 3146, 4860 GO:0032989 BP e cellular component morphogenesis 3/100 236/19669 0.118978912215777 4 3 0.5035153284259443 60, 351, 581 GO:0032990 BP e cell part morphogenesis 3/100 236/19669 0.118978912215777 5 3 0.5035153284259443 60, 351, 581 GO:0031398 BP e positive regulation of protein ubiquitination 2/100 117/19669 0.1194625037962025 10 2 0.5035153284259443 3309, 5071 GO:0002790 BP e peptide secretion 2/100 117/19669 0.1194625037962025 8 2 0.5035153284259443 821, 3569 GO:0072331 BP e signal transduction by p53 class mediator 2/100 117/19669 0.1194625037962025 6 2 0.5035153284259443 581, 83667 GO:0043666 BP e regulation of phosphoprotein phosphatase activity 2/100 117/19669 0.1194625037962025 9 2 0.5035153284259443 3064, 9104 GO:0061061 BP e muscle structure development 2/100 118/19669 0.1211369756325959 3 2 0.5093710532747682 3479, 3627 GO:0001503 BP e ossification 2/100 119/19669 0.1228172941090793 2 2 0.5160136926941662 4313, 4318 GO:0060964 BP e regulation of gene silencing by miRNA 2/100 119/19669 0.1228172941090793 8 2 0.5160136926941662 3569, 5468 GO:0017015 BP e regulation of transforming growth factor beta receptor signaling pathway 2/100 119/19669 0.1228172941090793 7 2 0.5160136926941662 3309, 5465 GO:0046942 BP e carboxylic acid transport 3/100 240/19669 0.1234184617107386 8 3 0.5183979600786758 1244, 5663, 9971 GO:0050864 BP e regulation of B cell activation 2/100 120/19669 0.1245033581148999 7 2 0.5194108651093277 196, 3569 GO:1904375 BP e regulation of protein localization to cell periphery 2/100 120/19669 0.1245033581148999 6 2 0.5194108651093277 60, 3458 GO:0043244 BP e regulation of protein-containing complex disassembly 2/100 120/19669 0.1245033581148999 5 2 0.5194108651093277 2934, 136319 GO:0060147 BP e regulation of posttranscriptional gene silencing 2/100 121/19669 0.1261950673848805 7 2 0.5261831717836118 3569, 5468 GO:0046034 BP e ATP metabolic process 2/100 121/19669 0.1261950673848805 2 2 0.5261831717836118 229, 2023 GO:0060966 BP e regulation of gene silencing by RNA 2/100 122/19669 0.1278923225084083 7 2 0.532682772233939 3569, 5468 GO:0007423 BP e sensory organ development 2/100 122/19669 0.1278923225084083 4 2 0.532682772233939 3146, 7422 GO:0007043 BP e cell-cell junction assembly 2/100 122/19669 0.1278923225084083 6 2 0.532682772233939 60, 9971 GO:1903844 BP e regulation of cellular response to transforming growth factor beta stimulus 2/100 122/19669 0.1278923225084083 5 2 0.532682772233939 3309, 5465 GO:0015980 BP e energy derivation by oxidation of organic compounds 2/100 123/19669 0.1295950249273949 4 2 0.536868757370823 847, 5836 GO:0098727 BP e maintenance of cell number 2/100 123/19669 0.1295950249273949 2 2 0.536868757370823 3479, 4851 GO:0032355 BP e response to estradiol 2/100 124/19669 0.1313030769147593 5 2 0.5437689590959202 847, 1244 GO:0044782 BP e cilium organization 3/100 247/19669 0.1313313333956813 6 3 0.5437689590959202 2934, 4851, 10096 GO:0006812 BP e cation transport 7/100 808/19669 0.132211598822847 5 7 0.547266408252721 302, 1244, 1356, 3934, 5071, 5663, 6622 GO:1905477 BP e positive regulation of protein localization to membrane 2/100 126/19669 0.1347348428639989 7 2 0.5550238842818371 3458, 5071 GO:1901657 BP e glycosyl compound metabolic process 2/100 127/19669 0.1364583655281612 4 2 0.5619733062559277 4831, 4860 GO:0034329 BP e cell junction assembly 3/100 253/19669 0.1382533836901117 5 3 0.567240622498219 60, 351, 9971 GO:0006282 BP e regulation of DNA repair 2/100 129/19669 0.1399202181577496 7 2 0.5739264811961 3146, 5591 GO:0044772 BP e mitotic cell cycle phase transition 3/100 255/19669 0.1405882897421593 4 3 0.5765131305973441 5243, 7846, 10383 GO:0045727 BP e positive regulation of translation 2/100 130/19669 0.1416583616983834 8 2 0.5767915810177926 3569, 5591 GO:0061138 BP e morphogenesis of a branching epithelium 2/100 131/19669 0.1434011937951894 5 2 0.5826146706726415 4851, 7422 GO:0007189 BP e adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/100 131/19669 0.1434011937951894 7 2 0.5826146706726415 3627, 4831 GO:0017148 BP e negative regulation of translation 2/100 132/19669 0.1451486232336259 8 2 0.5895585409251791 1719, 83667 GO:0044770 BP e cell cycle phase transition 3/100 263/19669 0.1500599376259473 3 3 0.606934837873269 5243, 7846, 10383 GO:0051783 BP e regulation of nuclear division 2/100 135/19669 0.1504175953261602 6 2 0.606934837873269 3479, 3553 GO:0048608 BP e reproductive structure development 3/100 264/19669 0.1512583011387674 3 3 0.6093888100852436 581, 5468, 7422 GO:0000278 BP e mitotic cell cycle 2/100 136/19669 0.1521825177535301 3 2 0.6123108361377332 7846, 10383 GO:1903322 BP e positive regulation of protein modification by small protein conjugation or removal 2/100 136/19669 0.1521825177535301 9 2 0.6123108361377332 3309, 5071 GO:0048871 BP e multicellular organismal homeostasis 2/100 136/19669 0.1521825177535301 4 2 0.6123108361377332 2876, 3553 GO:0031644 BP e regulation of nervous system process 2/100 136/19669 0.1521825177535301 5 2 0.6123108361377332 351, 4846 GO:0007417 BP e central nervous system development 2/100 136/19669 0.1521825177535301 4 2 0.6123108361377332 2934, 5071 GO:0060429 BP e epithelium development 2/100 137/19669 0.1539515931990085 4 2 0.6191050481663812 847, 4851 GO:1905039 BP e carboxylic acid transmembrane transport 2/100 137/19669 0.1539515931990085 9 2 0.6191050481663812 5243, 5663 GO:0000226 BP e microtubule cytoskeleton organization 4/100 408/19669 0.1542496939584449 6 4 0.620141794676193 3064, 4137, 7846, 10383 GO:1903825 BP e organic acid transmembrane transport 2/100 138/19669 0.1557247351287242 8 2 0.6231418808193101 5243, 5663 GO:0017038 BP e protein import 2/100 138/19669 0.1557247351287242 9 2 0.6231418808193101 348, 9131 GO:0070507 BP e regulation of microtubule cytoskeleton organization 2/100 138/19669 0.1557247351287242 7 2 0.6231418808193101 4137, 6622 GO:0001763 BP e morphogenesis of a branching structure 2/100 139/19669 0.1575018577161754 3 2 0.6300893138164648 4851, 7422 GO:0060968 BP e regulation of gene silencing 2/100 140/19669 0.1592828759255446 6 2 0.6334272507736777 3569, 5468 GO:0072594 BP e establishment of protein localization to organelle 4/100 418/19669 0.1638893630840305 6 4 0.6485619176814682 581, 847, 9131, 26061 GO:0009057 BP e macromolecule catabolic process 8/100 985/19669 0.1647391328193359 4 8 0.6517571347273984 302, 348, 2081, 3146, 3309, 4780, 5071, 5836 GO:0042886 BP e amide transport 11/100 1394/19669 0.1659809539087464 5 11 0.6565013828464683 348, 581, 821, 847, 3309, 3569, 5243, 5468, 5663, 9131, 26061 GO:0023061 BP e signal release 2/100 145/19669 0.168243476433682 6 2 0.6635743470821033 3569, 6622 GO:0051592 BP e response to calcium ion 2/100 145/19669 0.168243476433682 5 2 0.6635743470821033 2243, 3309 GO:0046434 BP e organophosphate catabolic process 2/100 147/19669 0.1718520918640944 5 2 0.6760440836660774 2876, 4860 GO:0055067 BP e monovalent inorganic cation homeostasis 2/100 147/19669 0.1718520918640944 7 2 0.6760440836660774 2896, 5166 GO:0051656 BP e establishment of organelle localization 3/100 283/19669 0.1745878401313933 4 3 0.6859603930615633 3064, 4137, 10096 GO:0051276 BP e chromosome organization 4/100 429/19669 0.174740639481147 5 4 0.686385513429008 3146, 4524, 5591, 9131 GO:0007034 BP e vacuolar transport 2/100 149/19669 0.1754736744980571 4 2 0.6890890151888488 2896, 5071 GO:0051701 BP e biological process involved in interaction with host 2/100 150/19669 0.1772891326561784 3 2 0.6944463607988255 9474, 26762 GO:0008360 BP e regulation of cell shape 2/100 150/19669 0.1772891326561784 6 2 0.6944463607988255 6347, 7422 GO:0001501 BP e skeletal system development 2/100 151/19669 0.1791075989602915 4 2 0.7012124009155144 3479, 4318 GO:0006325 BP e chromatin organization 6/100 713/19669 0.1799461672630904 4 6 0.7035409184767298 60, 3146, 4524, 5580, 9971, 23476 GO:0045930 BP e negative regulation of mitotic cell cycle 3/100 288/19669 0.1808908765215517 6 3 0.7051445262580246 581, 5591, 6347 GO:0030855 BP e epithelial cell differentiation 3/100 290/19669 0.183429579102415 4 3 0.7146787904775107 4851, 5468, 7422 GO:0007163 BP e establishment or maintenance of cell polarity 2/100 155/19669 0.1864100270736096 2 2 0.7237261141934542 60, 10096 GO:0031589 BP e cell-substrate adhesion 2/100 158/19669 0.1919147558480376 3 2 0.742289040588414 2243, 7450 GO:0009059 BP e macromolecule biosynthetic process 9/100 1150/19669 0.1935205278470859 4 9 0.7466234453664209 335, 348, 581, 3479, 3553, 4851, 5465, 5468, 9971 GO:0022900 BP e electron transport chain 2/100 160/19669 0.195596773327613 4 2 0.7544446971207933 4199, 50507 GO:0007268 BP e chemical synaptic transmission 3/100 300/19669 0.1962640926151397 7 3 0.7566393750869238 348, 5071, 6622 GO:0098916 BP e anterograde trans-synaptic signaling 3/100 300/19669 0.1962640926151397 6 3 0.7566393750869238 348, 5071, 6622 GO:0032774 BP e RNA biosynthetic process 5/100 533/19669 0.1990408897569232 7 5 0.7656184187350784 581, 4851, 5465, 5468, 9971 GO:0071103 BP e DNA conformation change 2/100 163/19669 0.2011366814154649 6 2 0.7721360755759555 3146, 9131 GO:0051897 BP e positive regulation of protein kinase B signaling 2/100 164/19669 0.2029875419524368 8 2 0.7790469502862852 1440, 2876 GO:0044262 BP e cellular carbohydrate metabolic process 2/100 165/19669 0.2048404010448343 4 2 0.7859620473896785 5836, 6652 GO:0120031 BP e plasma membrane bounded cell projection assembly 3/100 313/19669 0.2132681380563596 6 3 0.8114206785382878 2934, 4851, 10096 GO:0140056 BP e organelle localization by membrane tethering 2/100 171/19669 0.2159958000440358 4 2 0.8213924790406997 7846, 10383 GO:0035295 BP e tube development 2/100 171/19669 0.2159958000440358 3 2 0.8213924790406997 847, 4851 GO:0007010 BP e cytoskeleton organization 7/100 876/19669 0.2170816236738376 5 7 0.8243671863430486 60, 348, 3064, 4137, 6347, 7846, 10383 GO:0043161 BP e proteasome-mediated ubiquitin-dependent protein catabolic process 3/100 316/19669 0.2172380991632322 9 3 0.8243671863430486 3309, 4780, 5071 GO:0099537 BP e trans-synaptic signaling 3/100 316/19669 0.2172380991632322 5 3 0.8243671863430486 348, 5071, 6622 GO:2000027 BP e regulation of animal organ morphogenesis 2/100 173/19669 0.2197272759020458 5 2 0.8335229914055917 183, 7422 GO:0099536 BP e synaptic signaling 3/100 320/19669 0.2225558535361544 4 3 0.8419701538646552 348, 5071, 6622 GO:0001701 BP e in utero embryonic development 2/100 175/19669 0.2234644119162107 7 2 0.8449919654522071 4851, 7422 GO:0002478 BP e antigen processing and presentation of exogenous peptide antigen 2/100 175/19669 0.2234644119162107 4 2 0.8449919654522071 821, 1510 GO:0006650 BP e glycerophospholipid metabolic process 3/100 322/19669 0.2252247757417754 6 3 0.8510211879857412 335, 3030, 5130 GO:0003006 BP e developmental process involved in reproduction 7/100 898/19669 0.2261201611389463 2 7 0.8541947177045617 581, 4851, 5468, 5591, 6696, 7422, 9104 GO:0001505 BP e regulation of neurotransmitter levels 2/100 177/19669 0.227206715459768 3 2 0.8580886750738231 5071, 6622 GO:0010948 BP e negative regulation of cell cycle process 3/100 324/19669 0.2279001338917417 6 3 0.8604963347875138 581, 5591, 6347 GO:0045216 BP e cell-cell junction organization 2/100 179/19669 0.2309537030799099 5 2 0.8698917010278546 60, 9971 GO:0043009 BP e chordate embryonic development 2/100 179/19669 0.2309537030799099 6 2 0.8698917010278546 4851, 7422 GO:0015833 BP e peptide transport 10/100 1362/19669 0.2316991402413244 7 10 0.8724858743122053 348, 581, 821, 847, 3309, 3569, 5468, 5663, 9131, 26061 GO:0022406 BP e membrane docking 2/100 180/19669 0.232828804848095 2 2 0.8762486149355482 7846, 10383 GO:0030031 BP e cell projection assembly 3/100 329/19669 0.2346154148383833 5 3 0.8817414491728254 2934, 4851, 10096 GO:0051704 BP e multi-organism process 2/100 181/19669 0.2347049004509393 1 2 0.8818624067236223 302, 1244 GO:0015711 BP e organic anion transport 3/100 331/19669 0.2373117768818079 7 3 0.8899191633067798 1244, 5663, 9971 GO:0070588 BP e calcium ion transmembrane transport 2/100 183/19669 0.2384598421742121 8 2 0.8937888385438686 302, 5663 GO:0019884 BP e antigen processing and presentation of exogenous antigen 2/100 183/19669 0.2384598421742121 3 2 0.8937888385438686 821, 1510 GO:0010498 BP e proteasomal protein catabolic process 3/100 336/19669 0.2440766420023907 7 3 0.912699833638867 3309, 4780, 5071 GO:0048002 BP e antigen processing and presentation of peptide antigen 2/100 186/19669 0.2440982790940595 3 2 0.912699833638867 821, 1510 GO:0045664 BP e regulation of neuron differentiation 2/100 186/19669 0.2440982790940595 5 2 0.912699833638867 351, 4851 GO:0034220 BP e ion transmembrane transport 8/100 1028/19669 0.2520615279500273 5 8 0.939735202313692 302, 581, 1244, 3309, 5243, 5663, 9131, 83667 GO:0051641 BP e cellular localization 15/100 2220/19669 0.2645744857617181 2 15 0.9828147081517842 213, 348, 351, 581, 847, 3064, 3309, 4137, 5071, 7846, 9131, 9370, 10096, 10383, 26061 GO:0006310 BP e DNA recombination 2/100 197/19669 0.2648120046761496 7 2 0.9834596409184224 3146, 5591 GO:0009792 BP e embryo development ending in birth or egg hatching 2/100 198/19669 0.2666965757086584 5 2 0.9899807766898826 4851, 7422 GO:0050851 BP e antigen receptor-mediated signaling pathway 2/100 198/19669 0.2666965757086584 9 2 0.9899807766898826 581, 5663 GO:0006302 BP e double-strand break repair 2/100 200/19669 0.2704657679534894 8 2 1.0 3146, 5591 GO:0048812 BP e neuron projection morphogenesis 2/100 208/19669 0.2855362415388915 8 2 1.0 60, 351 GO:0007049 BP e cell cycle 4/100 441/19669 0.2898151818217891 2 4 1.0 196, 5580, 7846, 10383 GO:0046474 BP e glycerophospholipid biosynthetic process 2/100 211/19669 0.2911817945891264 7 2 1.0 335, 5130 GO:0120039 BP e plasma membrane bounded cell projection morphogenesis 2/100 213/19669 0.2949427604864531 7 2 1.0 60, 351 GO:0009790 BP e embryo development 2/100 214/19669 0.2968222949227186 4 2 1.0 4851, 7422 GO:0006457 BP e protein folding 2/100 215/19669 0.2987011413002958 2 2 1.0 821, 3309 GO:0055085 BP e transmembrane transport 9/100 1259/19669 0.3002640074891191 4 9 1.0 302, 335, 581, 1244, 3309, 5243, 5663, 9131, 83667 GO:0007188 BP e adenylate cyclase-modulating G protein-coupled receptor signaling pathway 2/100 216/19669 0.3005792583688197 6 2 1.0 3627, 4831 GO:0007186 BP e G protein-coupled receptor signaling pathway 9/100 1261/19669 0.3007330155479802 5 9 1.0 183, 335, 348, 351, 3627, 4831, 5468, 6347, 729230 GO:0048858 BP e cell projection morphogenesis 2/100 217/19669 0.302456605301022 6 2 1.0 60, 351 GO:0032984 BP e protein-containing complex disassembly 2/100 223/19669 0.3137022816394921 5 2 1.0 2934, 81631 GO:0033036 BP e macromolecule localization 13/100 1973/19669 0.3152961015936528 2 13 1.0 60, 348, 581, 821, 847, 3309, 5071, 5465, 5468, 5663, 9131, 9370, 26061 GO:0016072 BP e rRNA metabolic process 2/100 224/19669 0.3155731300909317 8 2 1.0 4137, 5591 GO:0009887 BP e animal organ morphogenesis 4/100 493/19669 0.3206406010454233 3 4 1.0 581, 5663, 6347, 7422 GO:0051259 BP e protein complex oligomerization 2/100 227/19669 0.3211790376295371 6 2 1.0 4143, 6622 GO:0046907 BP e intracellular transport 10/100 1445/19669 0.3318373750857377 4 10 1.0 348, 351, 581, 847, 3064, 3309, 4137, 7846, 9131, 26061 GO:0006816 BP e calcium ion transport 2/100 234/19669 0.3342161323318546 7 2 1.0 302, 5663 GO:0008654 BP e phospholipid biosynthetic process 2/100 248/19669 0.3600685342852273 6 2 1.0 335, 5130 GO:0048609 BP e multicellular organismal reproductive process 4/100 549/19669 0.3638241732476946 2 4 1.0 351, 383, 4851, 9104 GO:0007411 BP e axon guidance 2/100 255/19669 0.3728626080074967 4 2 1.0 4851, 7422 GO:0097485 BP e neuron projection guidance 2/100 256/19669 0.3746823073898545 3 2 1.0 4851, 7422 GO:0007264 BP e small GTPase mediated signal transduction 2/100 257/19669 0.3764999206715037 6 2 1.0 3162, 3479 GO:0007015 BP e actin filament organization 2/100 259/19669 0.3801287861368461 5 2 1.0 2934, 10096 GO:0033365 BP e protein localization to organelle 5/100 693/19669 0.4051869466389541 5 5 1.0 581, 847, 5071, 9131, 26061 GO:1903522 BP e regulation of blood circulation 2/100 273/19669 0.4052779130181112 5 2 1.0 183, 2243 GO:0048731 BP e system development 5/100 707/19669 0.4117863266382171 3 5 1.0 2934, 3479, 4318, 5071, 7422 GO:0015031 BP e protein transport 9/100 1336/19669 0.4207448400859748 8 9 1.0 348, 581, 821, 847, 3309, 5468, 5663, 9131, 26061 GO:0007389 BP e pattern specification process 3/100 359/19669 0.4333082285711253 2 3 1.0 4851, 5591, 5663 GO:0045184 BP e establishment of protein localization 9/100 1419/19669 0.4386653138365752 4 9 1.0 348, 581, 821, 847, 3309, 5468, 5663, 9131, 26061 GO:0006644 BP e phospholipid metabolic process 3/100 388/19669 0.4514853395146709 5 3 1.0 335, 3030, 5130 GO:0018193 BP e peptidyl-amino acid modification 6/100 857/19669 0.453349441073578 7 6 1.0 335, 2081, 4831, 5580, 5591, 9971 GO:0051301 BP e cell division 3/100 392/19669 0.4542650191964016 2 3 1.0 4851, 7846, 10096 GO:0008104 BP e protein localization 12/100 1951/19669 0.4999749645220321 3 12 1.0 60, 348, 581, 821, 847, 3309, 5071, 5468, 5663, 9131, 9370, 26061 GO:0034613 BP e cellular protein localization 7/100 1105/19669 0.5105027444970809 4 7 1.0 348, 581, 847, 5071, 9131, 9370, 26061 GO:0070727 BP e cellular macromolecule localization 7/100 1113/19669 0.5128021222714222 3 7 1.0 348, 581, 847, 5071, 9131, 9370, 26061 GO:0016070 BP e RNA metabolic process 9/100 1524/19669 0.5743564262725067 6 9 1.0 351, 581, 2081, 4137, 4851, 5465, 5468, 5591, 9971 GO:0044265 BP e cellular macromolecule catabolic process 5/100 832/19669 0.6163733332546654 5 5 1.0 2081, 3146, 3309, 4780, 5071 GO:0006886 BP e intracellular protein transport 5/100 850/19669 0.6228421775320823 9 5 1.0 581, 847, 3309, 9131, 26061 GO:0016579 BP e protein deubiquitination 2/100 275/19669 0.6525887061633906 9 2 1.0 60, 5071 GO:0090305 BP e nucleic acid phosphodiester bond hydrolysis 2/100 288/19669 0.6595911425214608 6 2 1.0 2081, 3146 GO:0070646 BP e protein modification by small protein removal 2/100 292/19669 0.6618618960221356 8 2 1.0 60, 5071 GO:0032259 BP e methylation 2/100 294/19669 0.6630159462233864 2 2 1.0 4143, 9971 GO:0030001 BP e metal ion transport 2/100 314/19669 0.6751567035338448 6 2 1.0 302, 5663 GO:0006605 BP e protein targeting 2/100 322/19669 0.6802724096664763 10 2 1.0 847, 26061 GO:0016570 BP e histone modification 2/100 351/19669 0.6996886063393146 7 2 1.0 5580, 9971 GO:0016569 BP e covalent chromatin modification 2/100 355/19669 0.7024452748118433 5 2 1.0 5580, 9971 GO:0048598 BP e embryonic morphogenesis 2/100 385/19669 0.723437283636155 3 2 1.0 4851, 5663 GO:0072657 BP e protein localization to membrane 3/100 489/19669 0.7400169710775193 5 3 1.0 348, 581, 9370 GO:0006511 BP e ubiquitin-dependent protein catabolic process 3/100 512/19669 0.7466567283880972 8 3 1.0 3309, 4780, 5071 GO:0019941 BP e modification-dependent protein catabolic process 3/100 518/19669 0.7485377874752542 7 3 1.0 3309, 4780, 5071 GO:0007600 BP e sensory perception 3/100 520/19669 0.7491773010105987 4 3 1.0 2876, 6347, 729230 GO:0043632 BP e modification-dependent macromolecule catabolic process 3/100 528/19669 0.7517948270850191 6 3 1.0 3309, 4780, 5071 GO:0098662 BP e inorganic cation transmembrane transport 3/100 561/19669 0.7634679399030054 7 3 1.0 302, 1244, 5663 GO:0051603 BP e proteolysis involved in cellular protein catabolic process 3/100 580/19669 0.7707040228922672 6 3 1.0 3309, 4780, 5071 GO:0090304 BP e nucleic acid metabolic process 11/100 2124/19669 0.8722424456730811 5 11 1.0 351, 581, 2081, 3146, 4137, 4851, 5465, 5468, 5591, 9971, 83667 GO:0034645 BP p cellular macromolecule biosynthetic process 3/100 897/19669 0.6309182123830651 5 3 1.0 335, 348, 3479 GO:0016071 BP p mRNA metabolic process 2/100 647/19669 0.7750805152558627 7 2 1.0 351, 2081 GO:0032446 BP p protein modification by small protein conjugation 3/100 808/19669 0.800415312984583 8 3 1.0 4780, 5071, 5591 GO:0006396 BP p RNA processing 3/100 838/19669 0.8018299845029767 7 3 1.0 351, 2081, 5591 GO:0070647 BP p protein modification by small protein conjugation or removal 4/100 1016/19669 0.8200483212078151 7 4 1.0 60, 4780, 5071, 5591 GO:0007275 BP p multicellular organism development 3/100 697/19669 1.0 3 3 1.0 1440, 4851, 7422 GO:0098655 BP p cation transmembrane transport 3/100 625/19669 1.0 6 3 1.0 302, 1244, 5663 GO:0007283 BP p spermatogenesis 2/100 403/19669 1.0 5 2 1.0 4851, 9104 GO:0007276 BP p gamete generation 2/100 451/19669 1.0 3 2 1.0 4851, 9104 GO:0098660 BP p inorganic ion transmembrane transport 3/100 651/19669 1.0 6 3 1.0 302, 1244, 5663 GO:0030029 BP p actin filament-based process 2/100 395/19669 1.0 2 2 1.0 60, 2934 GO:0043087 BP p regulation of GTPase activity 2/100 483/19669 1.0 5 2 1.0 6347, 9104 GO:0006397 BP p mRNA processing 2/100 442/19669 1.0 8 2 1.0 351, 2081 GO:0048232 BP p male gamete generation 2/100 407/19669 1.0 4 2 1.0 4851, 9104 GO:0034660 BP p ncRNA metabolic process 2/100 464/19669 1.0 7 2 1.0 4137, 5591 GO:0043547 BP p positive regulation of GTPase activity 2/100 409/19669 1.0 6 2 1.0 6347, 9104 GO:0006259 BP p DNA metabolic process 3/100 748/19669 1.0 6 3 1.0 3146, 5591, 83667 GO:0016567 BP p protein ubiquitination 3/100 731/19669 1.0 9 3 1.0 4780, 5071, 5591 GO:0006281 BP p DNA repair 2/100 502/19669 1.0 7 2 1.0 3146, 5591